| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Or Burstein, Motty Franko, Eyal Gale, Assaf Handelsman, Segev Barak, Shai Motsan, Alon Shamir, Roni Toledano, Omri Simhon, Yafit Hirshler, Gang Chen, Ravid Doro. Escitalopram and NHT normalized stress-induced anhedonia and molecular neuroadaptations in a mouse model of depression. PloS one. vol 12. issue 11. 2017-12-26. PMID:29141007. |
on a neurobiological aspect, ucms-induced reduction in hippocampal bdnf levels was normalized by escitalopram or nht, while ucms-induced reduction in striatal drd2 mrna levels was normalized solely by nht. |
2017-12-26 |
2023-08-13 |
mouse |
| Andiara E Freitas, Javier Egea, Izaskun Buendia, Vanessa Gómez-Rangel, Esther Parada, Elisa Navarro, Ana Isabel Casas, Aneta Wojnicz, José Avendaño Ortiz, Antonio Cuadrado, Ana Ruiz-Nuño, Ana Lúcia S Rodrigues, Manuela G Lope. Agmatine, by Improving Neuroplasticity Markers and Inducing Nrf2, Prevents Corticosterone-Induced Depressive-Like Behavior in Mice. Molecular neurobiology. vol 53. issue 5. 2017-12-25. PMID:25966970. |
in addition, agmatine treatment in control mice increased noradrenaline, serotonin, and dopamine levels, creb phosphorylation, mature bdnf and synaptotagmin i immunocontents, and reduced pro-bdnf immunocontent in the hippocampus. |
2017-12-25 |
2023-08-13 |
mouse |
| S Abad, J Camarasa, D Pubill, A Camins, E Escubed. Adaptive Plasticity in the Hippocampus of Young Mice Intermittently Exposed to MDMA Could Be the Origin of Memory Deficits. Molecular neurobiology. vol 53. issue 10. 2017-12-25. PMID:26687233. |
we cannot rule out the absence of mdma injury in the hippocampus being due to the generation of bdnf. |
2017-12-25 |
2023-08-13 |
mouse |
| Munder A Zagaar, An T Dao, Ibrahim A Alhaider, Karim A Alkadh. Prevention by Regular Exercise of Acute Sleep Deprivation-Induced Impairment of Late Phase LTP and Related Signaling Molecules in the Dentate Gyrus. Molecular neurobiology. vol 53. issue 5. 2017-12-22. PMID:25902862. |
sleep deprivation reduced the basal levels of phosphorylated camp response element-binding protein (p-creb) as well as other upstream modulators including calcium/calmodulin kinase iv (camkiv) and brain-derived neurotrophic factor (bdnf) in the dg of the hippocampus. |
2017-12-22 |
2023-08-13 |
rat |
| Francis L Pazini, Mauricio P Cunha, Julia M Rosa, André R S Colla, Vicente Lieberknecht, Ágatha Oliveira, Ana Lúcia S Rodrigue. Creatine, Similar to Ketamine, Counteracts Depressive-Like Behavior Induced by Corticosterone via PI3K/Akt/mTOR Pathway. Molecular neurobiology. vol 53. issue 10. 2017-12-22. PMID:26660117. |
moreover, corticosterone-treated mice presented a decreased hippocampal brain-derived neurotrophic factor (bdnf) level, an effect abolished by creatine or ketamine. |
2017-12-22 |
2023-08-13 |
mouse |
| Francis L Pazini, Mauricio P Cunha, Julia M Rosa, André R S Colla, Vicente Lieberknecht, Ágatha Oliveira, Ana Lúcia S Rodrigue. Creatine, Similar to Ketamine, Counteracts Depressive-Like Behavior Induced by Corticosterone via PI3K/Akt/mTOR Pathway. Molecular neurobiology. vol 53. issue 10. 2017-12-22. PMID:26660117. |
altogether, the results indicate that creatine shares with ketamine the ability to acutely reverse the corticosterone-induced depressive-like behavior by a mechanism dependent on pi3k/akt/mtor pathway, and modulation of the synaptic protein psd95 as well as bdnf in the hippocampus, indicating the relevance of targeting these proteins for the management of depressive disorders. |
2017-12-22 |
2023-08-13 |
mouse |
| A Luoni, A Berry, C Raggi, V Bellisario, F Cirulli, M A Riv. Sex-Specific Effects of Prenatal Stress on Bdnf Expression in Response to an Acute Challenge in Rats: a Role for Gadd45β. Molecular neurobiology. vol 53. issue 10. 2017-12-22. PMID:26676568. |
indeed, exposure to an acute stress upregulates bdnf expression in the prefrontal cortex, but not in the hippocampus, of control animals. |
2017-12-22 |
2023-08-13 |
rat |
| Hayat Banoujaafar, Alice Monnier, Nicolas Pernet, Aurore Quirié, Philippe Garnier, Anne Prigent-Tessier, Christine Mari. Brain BDNF levels are dependent on cerebrovascular endothelium-derived nitric oxide. The European journal of neuroscience. vol 44. issue 5. 2017-12-22. PMID:27306299. |
for this purpose, levels of bdnf and the phosphorylated form of endothelial no synthase at serine 1177 (p-enos) were simultaneously measured in the cortex and hippocampus of rats subjected to either bilateral common carotid occlusion (n = 6), physical exercise (n = 6) or a combination of both (n = 6) as experimental approaches to modulate flow-induced no production by the cerebrovasculature. |
2017-12-22 |
2023-08-13 |
rat |
| Ligia Mendes Soares, Erika Meyer, Humberto Milani, Harry W M Steinbusch, Jos Prickaerts, Rúbia M Weffort de Oliveir. The phosphodiesterase type 2 inhibitor BAY 60-7550 reverses functional impairments induced by brain ischemia by decreasing hippocampal neurodegeneration and enhancing hippocampal neuronal plasticity. The European journal of neuroscience. vol 45. issue 4. 2017-12-22. PMID:27813297. |
the effects of bay 60-7550 were evaluated on neuronal nuclei (neun), caspase-9, camp response element-binding protein (creb), phosphorylated creb (pcreb) and brain-derived neurotrophic factor (bdnf) expression in the hippocampus. |
2017-12-22 |
2023-08-13 |
mouse |
| Ligia Mendes Soares, Erika Meyer, Humberto Milani, Harry W M Steinbusch, Jos Prickaerts, Rúbia M Weffort de Oliveir. The phosphodiesterase type 2 inhibitor BAY 60-7550 reverses functional impairments induced by brain ischemia by decreasing hippocampal neurodegeneration and enhancing hippocampal neuronal plasticity. The European journal of neuroscience. vol 45. issue 4. 2017-12-22. PMID:27813297. |
ischemic mice also showed low bdnf protein levels in the hippocampus. |
2017-12-22 |
2023-08-13 |
mouse |
| Ligia Mendes Soares, Erika Meyer, Humberto Milani, Harry W M Steinbusch, Jos Prickaerts, Rúbia M Weffort de Oliveir. The phosphodiesterase type 2 inhibitor BAY 60-7550 reverses functional impairments induced by brain ischemia by decreasing hippocampal neurodegeneration and enhancing hippocampal neuronal plasticity. The European journal of neuroscience. vol 45. issue 4. 2017-12-22. PMID:27813297. |
concomitantly, bay 60-7550 enhanced expression of pcreb and bdnf protein levels in the hippocampus of ischemic mice. |
2017-12-22 |
2023-08-13 |
mouse |
| Mason L Yeh, Rajamani Selvam, Eric S Levin. BDNF-induced endocannabinoid release modulates neocortical glutamatergic neurotransmission. Synapse (New York, N.Y.). vol 71. issue 5. 2017-12-22. PMID:28164368. |
surprisingly, bdnf did not increase the frequency of spontaneous miniature excitatory postsynaptic currents (mepscs) onto layer 5 pyramidal neurons in somatosensory cortex, in contrast to its effects in the hippocampus and visual cortex. |
2017-12-22 |
2023-08-13 |
Not clear |
| b' Valentina Di Liberto, Monica Frinchi, Vincenzo Verdi, Angela Vitale, Fulvio Plescia, Carla Cannizzaro, Maria F Massenti, Natale Belluardo, Giuseppa Mud\\xc3\\xb. Anxiolytic effects of muscarinic acetylcholine receptors agonist oxotremorine in chronically stressed rats and related changes in BDNF and FGF2 levels in the hippocampus and prefrontal cortex. Psychopharmacology. vol 234. issue 4. 2017-12-21. PMID:27957715.' |
anxiolytic effects of muscarinic acetylcholine receptors agonist oxotremorine in chronically stressed rats and related changes in bdnf and fgf2 levels in the hippocampus and prefrontal cortex. |
2017-12-21 |
2023-08-13 |
rat |
| Alline C Campos, Natalia P Rocha, Jacques R Nicoli, Leda Q Vieira, Mauro M Teixeira, Antonio L Teixeir. Absence of gut microbiota influences lipopolysaccharide-induced behavioral changes in mice. Behavioural brain research. vol 312. 2017-12-19. PMID:27316342. |
after behavioral evaluation, animals were analyzed for possible changes in neuroplasticity by means of bdnf, ngf and cytokines levels in prefrontal cortex and hippocampus, and the expression of iba-1 (microglial activation marker) in the hippocampus, and the cellular activity marker, Δfosb, in the dorsal raphe nucleus. |
2017-12-19 |
2023-08-13 |
mouse |
| Phillip A Geist, Brooke N Dulka, Abigail Barnes, Michael Totty, Subimal Datt. BNDF heterozygosity is associated with memory deficits and alterations in cortical and hippocampal EEG power. Behavioural brain research. vol 332. 2017-12-19. PMID:28576309. |
we also examined the effects of bdnf reduction on cortical and hippocampal eeg spectral power via chronically implanted electrodes in the motor cortex and dorsal hippocampus. |
2017-12-19 |
2023-08-13 |
rat |
| Phillip A Geist, Brooke N Dulka, Abigail Barnes, Michael Totty, Subimal Datt. BNDF heterozygosity is associated with memory deficits and alterations in cortical and hippocampal EEG power. Behavioural brain research. vol 332. 2017-12-19. PMID:28576309. |
we found that bdnf ko rats were impaired in novelty recognition and fear memory retention, while hippocampal eeg power was decreased in slow waves and increased in fast waves. |
2017-12-19 |
2023-08-13 |
rat |
| G Hajiluian, G Nameni, P Shahabi, M Mesgari-Abbasi, S Sadigh-Eteghad, M A Farhang. Vitamin D administration, cognitive function, BBB permeability and neuroinflammatory factors in high-fat diet-induced obese rats. International journal of obesity (2005). vol 41. issue 4. 2017-12-18. PMID:28093570. |
the purpose of this research was to investigate the effects of vitamin d administration on cognitive function, nuclear factor-κb (nf-κb), brain-derived neurotrophic factor (bdnf) concentration in the hippocampus and blood-brain barrier (bbb) permeability in high-fat diet (hfd)-induced obese rats. |
2017-12-18 |
2023-08-13 |
rat |
| Shintaro Otsuka, Taro Ohkido, Makoto Itakura, Shigeru Watanabe, Saori Yamamori, Yuuki Iida, Masanori Saito, Hitoshi Miyaoka, Masami Takahash. Dual mechanisms of rapid expression of anxiety-related behavior in pilocarpine-treated epileptic mice. Epilepsy research. vol 123. 2017-12-15. PMID:27132018. |
among the hippocampal proteins tested, only brain derived-neurotrophic factor (bdnf) exhibited altered expression in parallel with anxiety-related behavior. |
2017-12-15 |
2023-08-13 |
mouse |
| Shintaro Otsuka, Taro Ohkido, Makoto Itakura, Shigeru Watanabe, Saori Yamamori, Yuuki Iida, Masanori Saito, Hitoshi Miyaoka, Masami Takahash. Dual mechanisms of rapid expression of anxiety-related behavior in pilocarpine-treated epileptic mice. Epilepsy research. vol 123. 2017-12-15. PMID:27132018. |
these results showed the possibility that bdnf expression in the hippocampus might cause anxiety-related behavior in adulthood. |
2017-12-15 |
2023-08-13 |
mouse |
| Jacobus C Schoeman, Stephanus F Steyn, Brian H Harvey, Christiaan B Brin. Long-lasting effects of fluoxetine and/or exercise augmentation on bio-behavioural markers of depression in pre-pubertal stress sensitive rats. Behavioural brain research. vol 323. 2017-12-13. PMID:28143768. |
furthermore, the combination of fluoxetine plus exercise reduced hippocampal bdnf levels as compared to exercise alone, which may explain the latter findings. |
2017-12-13 |
2023-08-13 |
rat |