| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Janna Aarse, Stefan Herlitze, Denise Manahan-Vaugha. The requirement of BDNF for hippocampal synaptic plasticity is experience-dependent. Hippocampus. vol 26. issue 6. 2018-01-08. PMID:26662461. |
in vitro, a specific role in hippocampal synaptic plasticity has been described, although not all experience-dependent forms of synaptic plasticity critically depend on bdnf. |
2018-01-08 |
2023-08-13 |
mouse |
| Junming Wang, Peili Duan, Ying Cui, Qing Li, Yanran Sh. Geniposide alleviates depression-like behavior via enhancing BDNF expression in hippocampus of streptozotocin-evoked mice. Metabolic brain disease. vol 31. issue 5. 2018-01-08. PMID:27311609. |
geniposide alleviates depression-like behavior via enhancing bdnf expression in hippocampus of streptozotocin-evoked mice. |
2018-01-08 |
2023-08-13 |
mouse |
| Junming Wang, Peili Duan, Ying Cui, Qing Li, Yanran Sh. Geniposide alleviates depression-like behavior via enhancing BDNF expression in hippocampus of streptozotocin-evoked mice. Metabolic brain disease. vol 31. issue 5. 2018-01-08. PMID:27311609. |
gp administration further elevated bdnf levels, and up-regulated the mrna expression of bdnf and tropomyosin-related kinase b (trkb) in hippocampus of diabetic mice. |
2018-01-08 |
2023-08-13 |
mouse |
| L Pietranera, J Correa, M E Brocca, P Roig, A Lima, N Di Giorgio, L M Garcia-Segura, A F De Nicol. Selective Oestrogen Receptor Agonists Rescued Hippocampus Parameters in Male Spontaneously Hypertensive Rats. Journal of neuroendocrinology. vol 28. issue 10. 2018-01-08. PMID:27517478. |
spontaneously hypertensive rats (shr) show pronounced hippocampus alterations, including low brain-derived neurotrophic factor (bdnf) expression, reduced neurogenesis, astrogliosis and increased aromatase expression. |
2018-01-08 |
2023-08-13 |
rat |
| Linda Nguyen, Brandon P Lucke-Wold, Aric F Logsdon, Anna L Scandinaro, Jason D Huber, Rae R Matsumot. Behavioral and biochemical effects of ketamine and dextromethorphan relative to its antidepressant-like effects in Swiss Webster mice. Neuroreport. vol 27. issue 14. 2018-01-08. PMID:27580401. |
western blots were used to measure bdnf and its precursor, pro-bdnf, protein expression in the hippocampus and the frontal cortex of these mice. |
2018-01-08 |
2023-08-13 |
mouse |
| Linda Nguyen, Brandon P Lucke-Wold, Aric F Logsdon, Anna L Scandinaro, Jason D Huber, Rae R Matsumot. Behavioral and biochemical effects of ketamine and dextromethorphan relative to its antidepressant-like effects in Swiss Webster mice. Neuroreport. vol 27. issue 14. 2018-01-08. PMID:27580401. |
ketamine also rapidly (within 40 min) increased pro-bdnf expression in an α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor-dependent manner in the hippocampus, whereas dm and imipramine did not alter pro-bdnf or bdnf levels in either the hippocampus or the frontal cortex within this timeframe. |
2018-01-08 |
2023-08-13 |
mouse |
| Krishna L Bharani, Rebecca Derex, Ann-Charlotte Granholm, Aurélie Ledreu. A noradrenergic lesion aggravates the effects of systemic inflammation on the hippocampus of aged rats. PloS one. vol 12. issue 12. 2018-01-08. PMID:29261743. |
specifically, dsp4+lps-treated rats in the short-term subgroup had lower hippocampal bdnf levels (~25%) than controls and lps-treated rats, which negatively correlated with hippocampal astrogliosis and positively correlated with hippocampal il-1β levels. |
2018-01-08 |
2023-08-13 |
rat |
| Krishna L Bharani, Rebecca Derex, Ann-Charlotte Granholm, Aurélie Ledreu. A noradrenergic lesion aggravates the effects of systemic inflammation on the hippocampus of aged rats. PloS one. vol 12. issue 12. 2018-01-08. PMID:29261743. |
serum and hippocampal bdnf levels in the dsp4+lps-treated rats in the long-term subgroup returned to levels similar to the control group. |
2018-01-08 |
2023-08-13 |
rat |
| Francesca Calabrese, Elisa Savino, Elisabeth Mocaer, Sylvie Bretin, Giorgio Racagni, Marco A Riv. Upregulation of neurotrophins by S 47445, a novel positive allosteric modulator of AMPA receptors in aged rats. Pharmacological research. vol 121. 2018-01-05. PMID:28442348. |
both the mrna and the protein levels of the neurotrophins bdnf, nt-3 and ngf were specifically measured in the prefrontal cortex and hippocampus (ventral and dorsal) of aged rats. |
2018-01-05 |
2023-08-13 |
rat |
| M Bardi, C Kaufman, C Franssen, M M Hyer, A Rzucidlo, M Brown, M Tschirhart, K G Lamber. Paper or Plastic? Exploring the Effects of Natural Enrichment on Behavioural and Neuroendocrine Responses in Long-Evans Rats. Journal of neuroendocrinology. vol 28. issue 5. 2018-01-04. PMID:26970429. |
the type of environmental enrichment did not influence levels of bdnf immunoreactivity in the ca1, ca3 and dentate gyrus of the hippocampus; however, natural environment animals exhibited higher levels of neun immunoreactivity in the retrosplenial cortex, an area involved in spatial memory and other cognitive functions. |
2018-01-04 |
2023-08-13 |
rat |
| Qi-Min Wang, Gui-Lin Wang, Ze-Gang M. Protective effects of myricetin on chronic stress-induced cognitive deficits. Neuroreport. vol 27. issue 9. 2018-01-04. PMID:27171032. |
the effect of myricetin on the levels of brain-derived neurotrophic factor (bdnf) in hippocampus was also investigated. |
2018-01-04 |
2023-08-13 |
mouse |
| Qi-Min Wang, Gui-Lin Wang, Ze-Gang M. Protective effects of myricetin on chronic stress-induced cognitive deficits. Neuroreport. vol 27. issue 9. 2018-01-04. PMID:27171032. |
these findings provide more evidence that chronic administration of myricetin improves spatial memory in repeatedly restrained mice and bdnf signaling in the hippocampus may be involved in the protective effects of myricetin. |
2018-01-04 |
2023-08-13 |
mouse |
| Ewa Obuchowicz, Marta Nowacka, Monika Paul-Samojedny, Anna M Bielecka-Wajdman, Andrzej Małeck. Sex differences in the effect of acute peripheral IL-1β administration on the brain and serum BDNF and VEGF expression in rats. Cytokine. vol 90. 2018-01-04. PMID:27744091. |
in male and female rats, the bdnf and vegf mrna expression, and bdnf level were evaluated in the amygdala, hippocampus, hypothalamus and pituitary gland. |
2018-01-04 |
2023-08-13 |
rat |
| Heow Won Lee, Monir Ahmad, Hong-Wei Wang, Frans H H Leene. Effects of exercise training on brain-derived neurotrophic factor in skeletal muscle and heart of rats post myocardial infarction. Experimental physiology. vol 102. issue 3. 2018-01-04. PMID:28070911. |
exercise training increases brain-derived neurotrophic factor (bdnf) in the hippocampus, which depends on a myokine, fibronectin type iii domain-containing protein 5 (fndc5). |
2018-01-04 |
2023-08-13 |
rat |
| Rita I Aroeira, Sandra H Vaz, Ana M Sebastião, Cláudia A Valent. BDNF modulates glycine uptake in hippocampal synaptosomes by decreasing membrane insertion of glycine transporter 2. Neurochemistry international. vol 99. 2018-01-03. PMID:27296115. |
bdnf modulates glycine uptake in hippocampal synaptosomes by decreasing membrane insertion of glycine transporter 2. |
2018-01-03 |
2023-08-13 |
rat |
| Rita I Aroeira, Sandra H Vaz, Ana M Sebastião, Cláudia A Valent. BDNF modulates glycine uptake in hippocampal synaptosomes by decreasing membrane insertion of glycine transporter 2. Neurochemistry international. vol 99. 2018-01-03. PMID:27296115. |
we herein show that bdnf decreases [(3)h]glycine uptake mediated by glyt2 in isolated nerve endings (synaptosomes) obtained from rat hippocampus, by reducing the maximum velocity (vmax) of transport while not influencing the transporter affinity constant (km) for glycine. |
2018-01-03 |
2023-08-13 |
rat |
| Atsushi Saito, Longjie Cai, Koji Matsuhisa, Yosuke Ohtake, Masayuki Kaneko, Soshi Kanemoto, Rie Asada, Kazunori Imaizum. Neuronal activity-dependent local activation of dendritic unfolded protein response promotes expression of brain-derived neurotrophic factor in cell soma. Journal of neurochemistry. vol 144. issue 1. 2018-01-02. PMID:28921568. |
here, we demonstrated that synaptic activity- and brain-derived neurotrophic factor (bdnf)-dependent local activation of upr signaling could be associated with dendritic functions through retrograde signal propagation by using murine neuroblastoma cell line, neuro-2a and primary cultured hippocampal neurons derived from postnatal day 0 litter c57bl/6 mice. |
2018-01-02 |
2023-08-13 |
mouse |
| Sarawut Lapmanee, Jantarima Charoenphandhu, Jarinthorn Teerapornpuntakit, Nateetip Krishnamra, Narattaphol Charoenphandh. Agomelatine, venlafaxine, and running exercise effectively prevent anxiety- and depression-like behaviors and memory impairment in restraint stressed rats. PloS one. vol 12. issue 11. 2017-12-29. PMID:29099859. |
moreover, western blot analysis demonstrated that venlafaxine and running exercise upregulated brain-derived neurotrophic factor (bdnf) expression in the hippocampus. |
2017-12-29 |
2023-08-13 |
rat |
| YuanBo Cui, ShanShan Ma, ChunYan Zhang, Wei Cao, Min Liu, DongPeng Li, PengJu Lv, Qu Xing, RuiNa Qu, Ning Yao, Bo Yang, FangXia Gua. Human umbilical cord mesenchymal stem cells transplantation improves cognitive function in Alzheimer's disease mice by decreasing oxidative stress and promoting hippocampal neurogenesis. Behavioural brain research. vol 320. 2017-12-27. PMID:28007537. |
the mechanisms underlying the improved cognitive function may be linked to hippocampal neurogenesis and an up-regulation of neuronal synaptic plasticity related proteins levels including silent information regulator 1 (sirt1), brain-derived neurotrophic factor (bdnf) and synaptophysin (syn). |
2017-12-27 |
2023-08-13 |
mouse |
| Or Burstein, Motty Franko, Eyal Gale, Assaf Handelsman, Segev Barak, Shai Motsan, Alon Shamir, Roni Toledano, Omri Simhon, Yafit Hirshler, Gang Chen, Ravid Doro. Escitalopram and NHT normalized stress-induced anhedonia and molecular neuroadaptations in a mouse model of depression. PloS one. vol 12. issue 11. 2017-12-26. PMID:29141007. |
biological indices pertinent to mdd and anhedonia were assessed: namely, hippocampal brain-derived neurotrophic factor (bdnf) and striatal dopamine receptor d2 (drd2) mrna expression levels. |
2017-12-26 |
2023-08-13 |
mouse |