| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yu Wang, Hong Liu, Ben-Shu Zhang, Jair C Soares, Xiang Yang Zhan. Low BDNF is associated with cognitive impairments in patients with Parkinson's disease. Parkinsonism & related disorders. vol 29. 2018-02-05. PMID:27245919. |
increasing evidence show that brain-derived neurotrophic factor (bdnf) plays a critical role in neuroplasticity in the hippocampus that is related to learning and memory. |
2018-02-05 |
2023-08-13 |
Not clear |
| Qian Zhang, Xueer Wang, Xuemei Bai, Yunkai Xie, Tiantian Zhang, Shishi Bo, Xiaoyang Che. Resveratrol reversed chronic restraint stress-induced impaired cognitive function in rats. Molecular medicine reports. vol 16. issue 2. 2018-02-05. PMID:28656303. |
in addition, crs exposure significantly decreased the mrna and protein expression levels of hippocampal brain‑derived neurotrophic factor (bdnf) in the rats. |
2018-02-05 |
2023-08-13 |
rat |
| Qian Zhang, Xueer Wang, Xuemei Bai, Yunkai Xie, Tiantian Zhang, Shishi Bo, Xiaoyang Che. Resveratrol reversed chronic restraint stress-induced impaired cognitive function in rats. Molecular medicine reports. vol 16. issue 2. 2018-02-05. PMID:28656303. |
in conclusion, the present study demonstrated that resveratrol may be a potential therapeutic agent for the treatment of chronic stress‑induced cognitive impairments, and its underlying molecular mechanism may be associated with the increased levels of hippocampal bdnf. |
2018-02-05 |
2023-08-13 |
rat |
| Weidong Wang, Xiaofeng Liu, Jinping Liu, Enbo Cai, Yan Zhao, Haijun Li, Lianxue Zhang, Pingya Li, Yugang Ga. Sesquiterpenoids from the Root of Panax ginseng Attenuates Lipopolysaccharide-Induced Depressive-Like Behavior through the Brain-Derived Neurotrophic Factor/Tropomyosin-Related Kinase B and Sirtuin Type 1/Nuclear Factor-κB Signaling Pathways. Journal of agricultural and food chemistry. vol 66. issue 1. 2018-02-05. PMID:29237268. |
in addition, spg effectively upregulated the brain-derived neurotrophic factor (bdnf), tropomyosin-related kinase b (trkb), and sirtuin type 1 (sirt 1) expression in the hippocampus and downregulated the inhibitor of κb-α (iκb-α) and nuclear factor-κb (nf-κb) phosphorylation. |
2018-02-05 |
2023-08-13 |
Not clear |
| A Özge Sungur, Magdalena C E Jochner, Hani Harb, Ayşe Kılıç, Holger Garn, Rainer K W Schwarting, Markus Wöh. Aberrant cognitive phenotypes and altered hippocampal BDNF expression related to epigenetic modifications in mice lacking the post-synaptic scaffolding protein SHANK1: Implications for autism spectrum disorder. Hippocampus. vol 27. issue 8. 2018-02-02. PMID:28500650. |
aberrant cognitive phenotypes and altered hippocampal bdnf expression related to epigenetic modifications in mice lacking the post-synaptic scaffolding protein shank1: implications for autism spectrum disorder. |
2018-02-02 |
2023-08-13 |
mouse |
| Richelle Mychasiuk, Harleen Hehar, Irene Ma, Sydney Candy, Michael J Esse. Reducing the time interval between concussion and voluntary exercise restores motor impairment, short-term memory, and alterations to gene expression. The European journal of neuroscience. vol 44. issue 7. 2018-02-01. PMID:27521273. |
using a translational rodent model of concussion, we examined the influence of exercise on injury-associated behaviours that comprise post-concussive syndrome (pcs) and gene expression changes (bdnf, dnmt1, igf-1, pgc1-a, tert) in prefrontal cortex and hippocampus. |
2018-02-01 |
2023-08-13 |
Not clear |
| Ming-Dong Zhang, Swapnali Barde, Ting Yang, Beilei Lei, Lars I Eriksson, Joseph P Mathew, Thomas Andreska, Katerina Akassoglou, Tibor Harkany, Tomas G M Hökfelt, Niccolò Terrand. Orthopedic surgery modulates neuropeptides and BDNF expression at the spinal and hippocampal levels. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 43. 2018-01-30. PMID:27791037. |
orthopedic surgery modulates neuropeptides and bdnf expression at the spinal and hippocampal levels. |
2018-01-30 |
2023-08-13 |
mouse |
| Ming-Dong Zhang, Swapnali Barde, Ting Yang, Beilei Lei, Lars I Eriksson, Joseph P Mathew, Thomas Andreska, Katerina Akassoglou, Tibor Harkany, Tomas G M Hökfelt, Niccolò Terrand. Orthopedic surgery modulates neuropeptides and BDNF expression at the spinal and hippocampal levels. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 43. 2018-01-30. PMID:27791037. |
in the hippocampus, bdnf protein levels were increased, yet there were no changes in bdnf mrna in the parent granule cell bodies. |
2018-01-30 |
2023-08-13 |
mouse |
| María S García-Gutiérrez, Francisco Navarrete, Auxiliadora Aracil, Adrián Bartoll, Isabel Martínez-Gras, José L Lanciego, Gabriel Rubio, Jorge Manzanare. Increased vulnerability to ethanol consumption in adolescent maternal separated mice. Addiction biology. vol 21. issue 4. 2018-01-29. PMID:25988842. |
alterations of the corticotropin-releasing factor (crf), glucocorticoid receptor (nr3c1), tyrosine hydroxylase (th), mu-opioid receptor (mor), brain-derived neurotrophic factor (bdnf), neuronal nuclei (neun), microtubule-associated protein 2 (map2) and neurofilament heavy (nf200)-immunoreactive fibers were studied in the paraventricular nucleus of the hypothalamus (pvn), ventral tegmental area (vta), nucleus accumbens (nac) or hippocampus (hip). |
2018-01-29 |
2023-08-13 |
mouse |
| Man Li, Wei Du, Feng Shao, Weiwen Wan. Cognitive dysfunction and epigenetic alterations of the BDNF gene are induced by social isolation during early adolescence. Behavioural brain research. vol 313. 2018-01-25. PMID:27435421. |
in contrast, the bdnf mrna levels, h3 acetylation of the bdnf gene and bdnf protein expression were decreased in the hippocampus of the isolation-reared rats. |
2018-01-25 |
2023-08-13 |
rat |
| Maria Moscoso-Castro, Irene Gracia-Rubio, Francisco Ciruela, Olga Valverd. Genetic blockade of adenosine A2A receptors induces cognitive impairments and anatomical changes related to psychotic symptoms in mice. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 7. 2018-01-23. PMID:27133030. |
finally, behavioral impairments were associated with enlargement of brain lateral ventricles and decreased bdnf levels in the hippocampus. |
2018-01-23 |
2023-08-13 |
mouse |
| Tetyana Chumak, Lukas Rüttiger, Sze Chim Lee, Dario Campanelli, Annalisa Zuccotti, Wibke Singer, Jiří Popelář, Katja Gutsche, Hyun-Soon Geisler, Sebastian Philipp Schraven, Mirko Jaumann, Rama Panford-Walsh, Jing Hu, Thomas Schimmang, Ulrike Zimmermann, Josef Syka, Marlies Knippe. BDNF in Lower Brain Parts Modifies Auditory Fiber Activity to Gain Fidelity but Increases the Risk for Generation of Central Noise After Injury. Molecular neurobiology. vol 53. issue 8. 2018-01-22. PMID:26476841. |
bdnf deletion profiles between these mice differ in the organ of corti (bdnf (pax2) -ko) versus the auditory cortex and hippocampus (bdnf (trkc) -ko). |
2018-01-22 |
2023-08-13 |
mouse |
| Tetyana Chumak, Lukas Rüttiger, Sze Chim Lee, Dario Campanelli, Annalisa Zuccotti, Wibke Singer, Jiří Popelář, Katja Gutsche, Hyun-Soon Geisler, Sebastian Philipp Schraven, Mirko Jaumann, Rama Panford-Walsh, Jing Hu, Thomas Schimmang, Ulrike Zimmermann, Josef Syka, Marlies Knippe. BDNF in Lower Brain Parts Modifies Auditory Fiber Activity to Gain Fidelity but Increases the Risk for Generation of Central Noise After Injury. Molecular neurobiology. vol 53. issue 8. 2018-01-22. PMID:26476841. |
reduced parvalbumin-positive contacts were found in the ascending auditory circuit, including the auditory cortex and hippocampus of bdnf (pax2) -ko, but not of bdnf (trkc) -ko mice. |
2018-01-22 |
2023-08-13 |
mouse |
| Hui Gao, Peipei Yan, Shun Zhang, Hao Huang, Fenghong Huang, Taoping Sun, Qianchun Deng, Qingde Huang, Sijing Chen, Keqiang Ye, Jiqu Xu, Liegang Li. Long-Term Dietary Alpha-Linolenic Acid Supplement Alleviates Cognitive Impairment Correlate with Activating Hippocampal CREB Signaling in Natural Aging Rats. Molecular neurobiology. vol 53. issue 7. 2018-01-16. PMID:26328539. |
memory performance correlated well with the activation of camp response element-binding protein (creb) and increases in both levels of brain-derived neurotrophic factor (bdnf) and its specific receptor tyrosine kinase b (trkb) phosphorylation in the hippocampus. |
2018-01-16 |
2023-08-13 |
rat |
| Fei Zheng, Ming Zhang, Qi Ding, Ferzin Sethna, Lily Yan, Changjong Moon, Miyoung Yang, Hongbing Wan. Voluntary running depreciates the requirement of Ca2+-stimulated cAMP signaling in synaptic potentiation and memory formation. Learning & memory (Cold Spring Harbor, N.Y.). vol 23. issue 8. 2018-01-16. PMID:27421897. |
running up-regulated exon ii mrna level of bdnf (brain-derived neurotrophic factor), though it failed to increase exon i and iv mrnas in the hippocampus of ac1 ko mice. |
2018-01-16 |
2023-08-13 |
mouse |
| Yili Zhang, Paul Smolen, Cristina M Alberini, Douglas A Baxter, John H Byrn. Computational model of a positive BDNF feedback loop in hippocampal neurons following inhibitory avoidance training. Learning & memory (Cold Spring Harbor, N.Y.). vol 23. issue 12. 2018-01-16. PMID:27918277. |
computational model of a positive bdnf feedback loop in hippocampal neurons following inhibitory avoidance training. |
2018-01-16 |
2023-08-13 |
Not clear |
| Somayeh Niknazar, Arezo Nahavandi, Ali Asghar Peyvandi, Hassan Peyvandi, Amin Shams Akhtari, Mohsen Karim. Comparison of the Adulthood Chronic Stress Effect on Hippocampal BDNF Signaling in Male and Female Rats. Molecular neurobiology. vol 53. issue 6. 2018-01-15. PMID:26189832. |
comparison of the adulthood chronic stress effect on hippocampal bdnf signaling in male and female rats. |
2018-01-15 |
2023-08-13 |
rat |
| Somayeh Niknazar, Arezo Nahavandi, Ali Asghar Peyvandi, Hassan Peyvandi, Amin Shams Akhtari, Mohsen Karim. Comparison of the Adulthood Chronic Stress Effect on Hippocampal BDNF Signaling in Male and Female Rats. Molecular neurobiology. vol 53. issue 6. 2018-01-15. PMID:26189832. |
the present study was undertaken to investigate differences in the change in expression of brain-derived neurotrophic factor (bdnf), and its tyrosine intracellular kinase-activating receptor (trkb) genes in the male and female rats' hippocampus (hpc) under chronic mild repeated stress (cmrs) conditions. |
2018-01-15 |
2023-08-13 |
rat |
| Ana Saavedra, Mar Puigdellívol, Shiraz Tyebji, Pradeep Kurup, Jian Xu, Silvia Ginés, Jordi Alberch, Paul J Lombroso, Esther Pérez-Navarr. BDNF Induces Striatal-Enriched Protein Tyrosine Phosphatase 61 Degradation Through the Proteasome. Molecular neurobiology. vol 53. issue 6. 2018-01-15. PMID:26223799. |
bdnf also promoted ups-mediated step61 degradation in cultured striatal and hippocampal neurons. |
2018-01-15 |
2023-08-13 |
Not clear |
| Clarissa B Haas, Eduardo Kalinine, Eduardo R Zimmer, Gisele Hansel, Andressa W Brochier, Jean P Oses, Luis V Portela, Alexandre P Mulle. Brain Insulin Administration Triggers Distinct Cognitive and Neurotrophic Responses in Young and Aged Rats. Molecular neurobiology. vol 53. issue 9. 2018-01-15. PMID:26497034. |
interestingly, insulin treatment increased the expression of the brain-derived neurotrophic factor (bdnf) and tropomyosin receptor kinase b (trkb) receptors in the hippocampus of young rats, but not of aged rats. |
2018-01-15 |
2023-08-13 |
rat |