| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Monzurul Amin Roni, Shafiqur Rahma. Lobeline attenuates ethanol abstinence-induced depression-like behavior in mice. Alcohol (Fayetteville, N.Y.). vol 61. 2018-02-27. PMID:28554528. |
abstinence from chronic ethanol exposure also decreased brain-derived neurotrophic factor (bdnf) in the dentate gyrus and ca3 region of the hippocampus. |
2018-02-27 |
2023-08-13 |
mouse |
| Sakineh Shafia, Abbas Ali Vafaei, Seyed Afshin Samaei, Ahmad Reza Bandegi, Alireza Rafiei, Reza Valadan, Zahra Hosseini-Khah, Raziyeh Mohammadkhani, Ali Rashidy-Pou. Effects of moderate treadmill exercise and fluoxetine on behavioural and cognitive deficits, hypothalamic-pituitary-adrenal axis dysfunction and alternations in hippocampal BDNF and mRNA expression of apoptosis - related proteins in a rat model of post-traumatic stress disorder. Neurobiology of learning and memory. vol 139. 2018-02-26. PMID:28137660. |
effects of moderate treadmill exercise and fluoxetine on behavioural and cognitive deficits, hypothalamic-pituitary-adrenal axis dysfunction and alternations in hippocampal bdnf and mrna expression of apoptosis - related proteins in a rat model of post-traumatic stress disorder. |
2018-02-26 |
2023-08-13 |
rat |
| Sakineh Shafia, Abbas Ali Vafaei, Seyed Afshin Samaei, Ahmad Reza Bandegi, Alireza Rafiei, Reza Valadan, Zahra Hosseini-Khah, Raziyeh Mohammadkhani, Ali Rashidy-Pou. Effects of moderate treadmill exercise and fluoxetine on behavioural and cognitive deficits, hypothalamic-pituitary-adrenal axis dysfunction and alternations in hippocampal BDNF and mRNA expression of apoptosis - related proteins in a rat model of post-traumatic stress disorder. Neurobiology of learning and memory. vol 139. 2018-02-26. PMID:28137660. |
we also examined alternations in hippocampal brain-derived neurotrophic factor (bdnf) and mrna expression of apoptosis - related proteins in a rat model of ptsd: the single prolonged stress (sps) model. |
2018-02-26 |
2023-08-13 |
rat |
| Sakineh Shafia, Abbas Ali Vafaei, Seyed Afshin Samaei, Ahmad Reza Bandegi, Alireza Rafiei, Reza Valadan, Zahra Hosseini-Khah, Raziyeh Mohammadkhani, Ali Rashidy-Pou. Effects of moderate treadmill exercise and fluoxetine on behavioural and cognitive deficits, hypothalamic-pituitary-adrenal axis dysfunction and alternations in hippocampal BDNF and mRNA expression of apoptosis - related proteins in a rat model of post-traumatic stress disorder. Neurobiology of learning and memory. vol 139. 2018-02-26. PMID:28137660. |
sps rats also showed reduced hippocampal bdnf and enhanced apoptosis. |
2018-02-26 |
2023-08-13 |
rat |
| Sakineh Shafia, Abbas Ali Vafaei, Seyed Afshin Samaei, Ahmad Reza Bandegi, Alireza Rafiei, Reza Valadan, Zahra Hosseini-Khah, Raziyeh Mohammadkhani, Ali Rashidy-Pou. Effects of moderate treadmill exercise and fluoxetine on behavioural and cognitive deficits, hypothalamic-pituitary-adrenal axis dysfunction and alternations in hippocampal BDNF and mRNA expression of apoptosis - related proteins in a rat model of post-traumatic stress disorder. Neurobiology of learning and memory. vol 139. 2018-02-26. PMID:28137660. |
moderate treadmill exercise, fluoxetine and the combined treatment alleviated the sps-induced alterations in terms of anxiety levels, hpa axis inhibition, ia conditioning and extinction, hippocampal bdnf and apoptosis markers. |
2018-02-26 |
2023-08-13 |
rat |
| Beita Zhao, Bo Ren, Rui Guo, Wentong Zhang, Shaobo Ma, Yuchen Yao, Tian Yuan, Zhigang Liu, Xuebo Li. Supplementation of lycopene attenuates oxidative stress induced neuroinflammation and cognitive impairment via Nrf2/NF-κB transcriptional pathway. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 109. issue Pt 1. 2018-02-26. PMID:28974442. |
lyc ameliorated histopathological damage and restored brain derived neurotrophic factor (bdnf) levels in the hippocampus of mice. |
2018-02-26 |
2023-08-13 |
mouse |
| Cristiane Signor, Bruna Amanda Girardi, Arithane Lorena Wendel, Pâmella Karina Santana Frühauf, Micheli M Pillat, Henning Ulrich, Carlos F Mello, Maribel A Rubi. Spermidine improves the persistence of reconsolidated fear memory and neural differentiation in vitro: Involvement of BDNF. Neurobiology of learning and memory. vol 140. 2018-02-22. PMID:28254465. |
the facilitatory effect of spermidine on the persistence of reconsolidated memory was blocked by the trkb inhibitor ana-12 (73.6pmol/site) and accompanied by mature bdnf level increase in the hippocampus, indicating that it depends on the bdnf/trkb pathway. |
2018-02-22 |
2023-08-13 |
rat |
| Koichi Uegaki, Haruko Kumanogoh, Toshiyuki Mizui, Takatsugu Hirokawa, Yasuyuki Ishikawa, Masami Kojim. BDNF Binds Its Pro-Peptide with High Affinity and the Common Val66Met Polymorphism Attenuates the Interaction. International journal of molecular sciences. vol 18. issue 5. 2018-02-22. PMID:28498321. |
lastly, we performed electrophysiological experiments, which indicated that the bdnf pro-peptide, when pre-incubated with bdnf, attenuated the ability of bdnf to inhibit hippocampal long-term depression (ltd), suggesting a possibility that the bdnf pro-peptide may interact directly with bdnf and thereby inhibit its availability. |
2018-02-22 |
2023-08-13 |
human |
| A C Venezia, E Quinlan, S M Rot. A single bout of exercise increases hippocampal Bdnf: influence of chronic exercise and noradrenaline. Genes, brain, and behavior. vol 16. issue 8. 2018-02-22. PMID:28556463. |
a single bout of exercise increases hippocampal bdnf: influence of chronic exercise and noradrenaline. |
2018-02-22 |
2023-08-13 |
mouse |
| A C Venezia, E Quinlan, S M Rot. A single bout of exercise increases hippocampal Bdnf: influence of chronic exercise and noradrenaline. Genes, brain, and behavior. vol 16. issue 8. 2018-02-22. PMID:28556463. |
here we use a rodent model to investigate the effects of acute and chronic exercise on hippocampal transcript-specific bdnf expression and phosphorylation of the glur1 subunit of the ampa-type glutamate receptor. |
2018-02-22 |
2023-08-13 |
mouse |
| Hsiang Liao, Liang-Mao Chou, Yi-Wen Chien, Chi-Hao Wu, Jung-Su Chang, Ching-I Lin, Shyh-Hsiang Li. Grape powder consumption affects the expression of neurodegeneration-related brain proteins in rats chronically fed a high-fructose-high-fat diet. The Journal of nutritional biochemistry. vol 43. 2018-02-19. PMID:28285155. |
western blotting was performed to measure the expression/phosphorylation levels of several cortical and hippocampal proteins, including amyloid precursor protein (app), tau, phosphatidylinositol-3-kinase (pi3k), extracellular signal-regulated kinase (erk), receptor for advanced glycation end products (rages), erythroid 2-related factor 2 (nrf2) and brain-derived neurotrophic factor (bdnf). |
2018-02-19 |
2023-08-13 |
rat |
| Lili Zhou, Qingming Lin, Peng Wang, Lan Yao, Kahong Leong, Zhiqun Tan, Zitong Huan. Enhanced neuroprotective efficacy of bone marrow mesenchymal stem cells co-overexpressing BDNF and VEGF in a rat model of cardiac arrest-induced global cerebral ischemia. Cell death & disease. vol 8. issue 5. 2018-02-16. PMID:28492549. |
we demonstrate that anchorage of lentiviral vector-transduced bmmscs, which co-overexpressed both bdnf and vegf in the hippocampus and temporal cortex along with significantly ameliorated brain pathology and improved neurofunctional performance in ca-gcii rats after transplantation. |
2018-02-16 |
2023-08-13 |
rat |
| Lindsey C Vedder, Lisa M Savag. BDNF regains function in hippocampal long-term potentiation deficits caused by diencephalic damage. Learning & memory (Cold Spring Harbor, N.Y.). vol 24. issue 2. 2018-02-12. PMID:28096497. |
bdnf regains function in hippocampal long-term potentiation deficits caused by diencephalic damage. |
2018-02-12 |
2023-08-13 |
rat |
| Lindsey C Vedder, Lisa M Savag. BDNF regains function in hippocampal long-term potentiation deficits caused by diencephalic damage. Learning & memory (Cold Spring Harbor, N.Y.). vol 24. issue 2. 2018-02-12. PMID:28096497. |
however, both measures of hippocampal plasticity (ltp, ppf) were restored with brain-derived neurotrophic factor (bdnf), revealing an avenue for neural and behavioral recovery following diencephalic damage. |
2018-02-12 |
2023-08-13 |
rat |
| Muhammad Zahid Khan, Xuxu Zhuang, Ling H. GPR40 receptor activation leads to CREB phosphorylation and improves cognitive performance in an Alzheimer's disease mouse model. Neurobiology of learning and memory. vol 131. 2018-02-09. PMID:26976092. |
furthermore, we have observed that activation of gpr40 receptor provoked the phosphorylation of the camp response element binding protein (creb) and significant increase in neurotropic factors including brain derived neurotrophic factor (bdnf), nerve growth factor (ngf), neurotrophin-3 (nt-3), neurotrohin-4 (nt-4) in mouse hippocampal neurons and contribute to neurogenesis. |
2018-02-09 |
2023-08-13 |
mouse |
| Majid Motaghinejad, Manijeh Motevalian, Fatemeh Babalouei, Mohammad Abdollahi, Mansour Heidari, Zahra Madj. Possible involvement of CREB/BDNF signaling pathway in neuroprotective effects of topiramate against methylphenidate induced apoptosis, oxidative stress and inflammation in isolated hippocampus of rats: Molecular, biochemical and histological evidences. Brain research bulletin. vol 132. 2018-02-09. PMID:28552672. |
expression of total (inactive) and phosphorylated (active) creb and bdnf were also measured in gene and protein levels in dentate gyrus (dg) and ca1 areas of hippocampus. |
2018-02-09 |
2023-08-13 |
rat |
| S Caughey, A P Harris, J R Seckl, M C Holmes, J L W Ya. Forebrain-Specific Transgene Rescue of 11β-HSD1 Associates with Impaired Spatial Memory and Reduced Hippocampal Brain-Derived Neurotrophic Factor mRNA Levels in Aged 11β-HSD1 Deficient Mice. Journal of neuroendocrinology. vol 29. issue 1. 2018-02-08. PMID:27859809. |
brain-derived neurotrophic factor (bdnf) mrna levels in the hippocampus of aged hsd1ko mice were increased compared to aged wild-type mice. |
2018-02-08 |
2023-08-13 |
mouse |
| S Caughey, A P Harris, J R Seckl, M C Holmes, J L W Ya. Forebrain-Specific Transgene Rescue of 11β-HSD1 Associates with Impaired Spatial Memory and Reduced Hippocampal Brain-Derived Neurotrophic Factor mRNA Levels in Aged 11β-HSD1 Deficient Mice. Journal of neuroendocrinology. vol 29. issue 1. 2018-02-08. PMID:27859809. |
these findings indicate that 11β-hsd1 regenerated glucocorticoids in the forebrain and decreased levels of bdnf mrna in the hippocampus play a role in spatial memory deficits in aged wild-type mice, although 11β-hsd1 activity in peripheral tissues may also contribute to spatial learning impairments in aged mice. |
2018-02-08 |
2023-08-13 |
mouse |
| Wei-Gang Gong, Yan-Juan Wang, Hong Zhou, Xiao-Li Li, Feng Bai, Qing-Guo Ren, Zhi-Jun Zhan. Citalopram Ameliorates Synaptic Plasticity Deficits in Different Cognition-Associated Brain Regions Induced by Social Isolation in Middle-Aged Rats. Molecular neurobiology. vol 54. issue 3. 2018-02-07. PMID:26899575. |
furthermore, si reduced the levels of bdnf, serine-473-phosphorylated akt (active form), and serine-9-phosphorylated gsk-3β (inactive form) with no significant changes in the levels of total gsk-3β and akt in the dorsal hippocampus, but not in the posterior cingulate. |
2018-02-07 |
2023-08-13 |
rat |
| Dilek Özbeyli, Gülce Sarı, Naziye Özkan, Betül Karademir, Meral Yüksel, Özlem Tuğçe Çilingir Kaya, Özgür Kasımay Çakı. Protective effects of different exercise modalities in an Alzheimer's disease-like model. Behavioural brain research. vol 328. 2018-02-07. PMID:28390878. |
hippocampal mrna levels of nerve growth factor (ngf), brain derived neurotrophic factor (bdnf), and amyloid precursor protein 695 (app695) were measured. |
2018-02-07 |
2023-08-13 |
rat |