| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| X Yan, K-J Mu, Q Wen, J Bian, D Yang, W-N Gao, W-M Zhan. Analyzing the impact of acupuncture in conjunction with a Quantum lipid-lowering device on hyperlipidemic rats: insights into adenosine monophosphate-activated protein kinase signaling, blood lipids, and gut microbiota. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 75. issue 3. 2024-07-23. PMID:39042391. |
elisa results showed that compared with the model group, acup + quantum group could reduce the levels of total cholesterol (tc), triglycerides (tg), low-density lipoprotein-cholesterol (ldl-c), aspartate transaminase (ast) and aspartate transaminase (alt) in rats with hyperlipidemia (p<0.01), and increase the level of high-density lipoprotein-cholesterol (hdl-c) (p<0.01). |
2024-07-23 |
2024-07-25 |
rat |
| Jie Wei, Xian Tang, Yujing He, Ziheng Peng, Hongwei Liu, Yin He, Jun Ga. Aronia Melanocarpa Elliot Anthocyanins Inhibits Alcoholic Liver Disease by Activation of α7nAChR. Plant foods for human nutrition (Dordrecht, Netherlands). 2024-07-10. PMID:38985368. |
mice were treated by intragastric administration of gradient 50% ethanol, ama alleviated liver injury by ald and ameliorated the model's body weight, lessened the liver inflammation according to histopathological evaluation, increased serum liver biochemical index (ast, alt, tc, tg and ldl-c) and decreased hdl-c, reversed the expression of enzymes (aldh and gsh-px), decreased cytokines expression (ki67, tnf-α and il-6), reversed the expression of α7nachr and collagen i, downregulated the pi3k-akt pathway and keap1/ho-1 pathway (p-pi3k, pi3k, p-akt, akt, keap1, nrf2, ho-1,gsk-3β and bcl-2), indicated that α7nachr and collagen i may be the ama action targets. |
2024-07-10 |
2024-07-12 |
mouse |
| S Morrone, S Sechi, C Carta, A Senes, R Cocco, M L Pinna Parpaglia, E Sanna Passino, M G Cappa. Nutritional management of hyperlipaemia in a jenny: a brief report. Veterinary research communications. 2024-07-04. PMID:38963468. |
blood analyses outlined a general undernourishment condition [circulating albumins, alb: 17.6 g/l (21.6-31.6 g/l)] with underlying systemic inflammatory profile and moderate increase in circulating enzymes to explore liver function [aspartate amino-transferase, ast: 657 u/l (279-430 u/l); alanine amino-transferase alt: 60 u/l (5-14 u/l); gamma-glutamyl-transferase, γ-gt: 87 iu/l (14-69 iu/l); total bilirubin close to the upper limit, tb: 0.20 mg/dl(0.07-0.21 mg/dl)]and hyperlipaemia [tg: 8.70 mmol/l (0.60-2.87 mmol/l)], following fat depots mobilisation, with total cholesterol closed to the lower limit of the physiological range. |
2024-07-04 |
2024-07-10 |
Not clear |
| J Gu, Y Chen, J Wang, Y Gao, Z Gai, Y Zhao, F X. Lacticaseibacillus rhamnosus LRa05 alleviated liver injury in mice with alcoholic fatty liver disease by improving intestinal permeability and balancing gut microbiota. Beneficial microbes. 2024-07-03. PMID:38960385. |
alcohol consumption induced liver damage in mice with significantly increased levels of triglycerides (tg), aspartate aminotransferase (ast), alanine transaminase (alt), and inflammatory cytokines. |
2024-07-03 |
2024-07-10 |
mouse |
| Tianming Yu, Le Wang, Yang Cheng, Yun Zhang, Jiankang Zhu, Guangyong Zhang, Sanyuan H. Downregulation of Setdb2 promotes alternative activation of macrophages via the PI3K/Akt pathway to attenuate NAFLD after sleeve gastrectomy. Biochemical and biophysical research communications. vol 726. 2024-06-21. PMID:38905784. |
sg prompted significant weight loss, diminished liver size and liver-to-body weight ratio, and enhanced liver function, evidenced by reduced serum levels of triglycerides (tg), total cholesterol (t-cho), alanine aminotransferase (alt), and aspartate aminotransferase (ast). |
2024-06-21 |
2024-06-24 |
mouse |
| Ju Huang, Meng-Ling Wang, Zi-Yue Zhou, Ting Yan, Hui Xiong, Zhi-Nan Me. [Mechanism of Biejiajian Pills against non-alcoholic steatohepatitis based on lipidomics]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 10. 2024-05-30. PMID:38812156. |
the results demonstrated that biejiajian pills notably lowered the levels of alanine aminotransferase(alt), aspartate aminotransferase(ast), and alkaline phosphatase(alp) in the serum and the levels of triglyceride(tg) and total cholesterol(tc) in the liver tissue. |
2024-05-30 |
2024-06-17 |
mouse |
| Sedef Ziyanok-Demirta. Therapeutic potentials of Hibiscus trionum: Antioxidant, anti-lipid peroxidative, hypoglycemic, and hepatoprotective effects in type 1 diabetic rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 175. 2024-04-27. PMID:38677247. |
serum total cholesterol (tc), triglyceride (tg), aspartate aminotransferase (ast), and alanine aminotransferase (alt) levels were evaluated. |
2024-04-27 |
2024-04-30 |
rat |
| Sedef Ziyanok-Demirta. Therapeutic potentials of Hibiscus trionum: Antioxidant, anti-lipid peroxidative, hypoglycemic, and hepatoprotective effects in type 1 diabetic rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 175. 2024-04-27. PMID:38677247. |
moreover, the diabetic group also showed increased levels of mda, tc, tg, ast, and alt, along with reduced insulin levels, compared to the control group. |
2024-04-27 |
2024-04-30 |
rat |
| Seung Tae Im, Heejoo Kang, Jusang Kim, Song-Rae Kim, Kil-Nam Kim, Seung-Hong Le. Narirutin-Rich Celluclast Extract from Mandarin ( International journal of molecular sciences. vol 25. issue 8. 2024-04-27. PMID:38674060. |
mpce also reduced triglyceride (tg), alanine transaminase (alt), aspartate transaminase (ast), and leptin contents in the serum of hfd-fed mice. |
2024-04-27 |
2024-04-29 |
mouse |
| Xixi Zeng, Ling Chen, Bo Zhen. Extrusion and chlorogenic acid treatment increase the ordered structure and resistant starch levels in rice starch with amelioration of gut lipid metabolism in obese rats. Food & function. 2024-04-16. PMID:38623646. |
compared to a physical mixture of starch and chlorogenic acid (cga + s), cga-es showed a more potent effect in alleviating lipid metabolism disorders, manifesting as reduced levels of blood glucose, serum total cholesterol (tc), triglycerides (tg), aspartate aminotransferase (ast), alanine transaminase (alt) and alkaline phosphatase (akp), as well as body weight. |
2024-04-16 |
2024-04-18 |
rat |
| Zhi Qin, Min Zho. [Tanshinone Ⅱ_A inhibits ferroptosis via Nrf2 signaling pathway to protect liver in rats of non-alcoholic fatty liver disease]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 6. 2024-04-15. PMID:38621946. |
a biochemical analyzer was used to measure the content of aspartate aminotransferase(ast), alaninl aminotransferase(alt), total cholesterol(tc), and triglycerides(tg). |
2024-04-15 |
2024-04-18 |
rat |
| Zhi Qin, Min Zho. [Tanshinone Ⅱ_A inhibits ferroptosis via Nrf2 signaling pathway to protect liver in rats of non-alcoholic fatty liver disease]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 6. 2024-04-15. PMID:38621946. |
the result showed that tsⅡ_a significantly reduced the content of mda, ast, alt, tc, and tg in the serum, increased the activity of sod, decreased the apoptosis rate, lipid deposition, ros, and iron deposition in the liver tissue, up-regulated the expression of nrf2, ho-1, fsp1, gpx, and bcl-2, and inhibited the expression of bax in the liver tissue of nafld rats. |
2024-04-15 |
2024-04-18 |
rat |
| Marcela C Sena, Fábio C Sterzelecki, Paola Fabiana F Gomes, Helen Cristiane A Souza, Nuno Filipe A Correia de Melo, J Natividade, B Baldisserotto, Glauber David A Palheta, Simone do Socorro D Santo. Maximum storage time of refrigerated blood and frozen plasma samples from tambaqui, Colossoma macropomum. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 2024-04-11. PMID:38604560. |
the parameters analyzed were hematocrit (ht), hemoglobin content (hb), total erythrocytes (rbc), total (wbc) and differential leukocytes, total thrombocytes (tc), glucose content (glc), total protein (tp), triglyceride content (tg), total cholesterol (cot), and the activities of alanine aminotransferase (alt) and aspartate aminotransferase (ast). |
2024-04-11 |
2024-04-14 |
Not clear |
| Mengyun Dong, Tianliang Zhang, Xueli Liang, Xinyi Cheng, Fuyan Shi, Hang Yuan, Fengxiang Zhang, Qiqi Jiang, Xia Wan. Sesamin alleviates lipid accumulation induced by oleic acid via PINK1/Parkin-mediated mitophagy in HepG2 cells. Biochemical and biophysical research communications. vol 708. 2024-03-26. PMID:38531220. |
cell viability was evaluated using the cck-8 method, and triglycerides (tg), total cholesterol (tc), high-density lipoprotein cholesterol (hdl-c), low-density lipoprotein, cholesterol (ldl-c), alanine aminotransferase (alt), along with aspartate aminotransferase (ast) were assessed by oil red o staining, transmission electron microscopy (tem), and biochemical kits to investigate the lipid-lowering effects of sesamin. |
2024-03-26 |
2024-03-29 |
Not clear |
| Jian Song, Bo-Feng Qin, Jin-Jin Zhang, Qi-Yuan Feng, Guan-Cheng Liu, Gui-Yun Zhao, Hai-Ming Su. Regulation of the Nur77-P2X7r Signaling Pathway by Nodakenin: A Potential Protective Function against Alcoholic Liver Disease. Molecules (Basel, Switzerland). vol 29. issue 5. 2024-03-13. PMID:38474588. |
in vivo, histopathological alterations were markedly alleviated by nk, accompanied by reductions in serum triglyceride (tg), aspartate aminotransferase (ast), and alanine aminotransferase (alt) levels and the modulation of lipin-1, srebp1, and nur77 levels in comparison to the etoh-exposed group ( |
2024-03-13 |
2024-03-15 |
mouse |
| Weiwen Lai, Shipeng Zhou, Yan Bai, Qishi Che, Hua Cao, Jiao Guo, Zhengquan S. Glucosamine attenuates alcohol-induced acute liver injury via inhibiting oxidative stress and inflammation. Current research in food science. vol 8. 2024-02-29. PMID:38420347. |
the results showed that glc can significantly inhibit the abnormal increase of aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp), lactate dehydrogenase (ldh), triglycerides (tg), total cholesterol (tc), very low density lipoprotein (vldl), low-density lipoprotein cholesterol (ldl-c), and can significantly improve the level of high-density lipoprotein cholesterol (hdl-c). |
2024-02-29 |
2024-03-02 |
mouse |
| Yujuan Yu, Fumao Zeng, Peiheng Han, Li Zhang, Ling Yang, Feng Zhou, Qing Liu, Zheng Rua. Dietary chlorogenic acid alleviates high-fat diet-induced steatotic liver disease by regulating metabolites and gut microbiota. International journal of food sciences and nutrition. 2024-02-23. PMID:38389248. |
in comparison to the hf group, the tc (total cholesterol), tg (total triglycerides), ldl-c (low-density lipoprotein cholesterol), ast (aspartate aminotransferase) and alt (alanine transaminase) levels were reduced after cga supplement. |
2024-02-23 |
2024-02-25 |
mouse |
| Ruofan Liu, Cuiyuan Mo, Xuetuan Wei, Aimin M. Hepatoprotective Effect of Annulohypoxylon stygium Melanin on Acute Alcoholic Liver Injury in Mice. Applied biochemistry and biotechnology. 2024-02-21. PMID:38381310. |
it was able to significantly decrease the activities of aspartate aminotransferase (ast) and alanine aminotransferase (alt), the contents of triglyceride (tg) and total cholesterol (tc) in mice. |
2024-02-21 |
2024-02-23 |
mouse |
| Guojun Wan, Zengli Zhang, Jingsi Chen, Mei Li, Jiafu L. GenX caused liver injury and potential hepatocellular carcinoma of mice via drinking water even at environmental concentration. Environmental pollution (Barking, Essex : 1987). 2024-02-16. PMID:38365076. |
genx was found to cause a dose-dependent increase in the serum levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), total cholesterol (tc), and triglyceride (tg). |
2024-02-16 |
2024-02-19 |
mouse |
| Penghui Zhao, Yinchen Hou, Xinyang Chen, Mingyi Zhang, Zheyuan Hu, Lishui Chen, Jihong Huan. High Fischer Ratio Oligopeptides of Gluten Alleviate Alcohol-Induced Liver Damage by Regulating Lipid Metabolism and Oxidative Stress in Rats. Foods (Basel, Switzerland). vol 13. issue 3. 2024-02-10. PMID:38338571. |
following intervention, the levels of serum total cholesterol (tc), triglyceride (tg), alanine aminotransferase (alt), aspartate aminotransferase (ast), and hepatic malondialdehyde (mda) in the rats significantly decreased ( |
2024-02-10 |
2024-02-12 |
rat |