| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tarique Aziz, Mukesh K Niraj, Shishir Kumar, Rajendra Kumar, Hina Parvee. Effectiveness of Omega-3 Polyunsaturated Fatty Acids in Non-alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis. Cureus. vol 16. issue 8. 2024-09-30. PMID:39347373. |
omega-3 supplementation significantly decreased alanine aminotransferase (alt) (mean difference = -2.12, 95% confidence interval (ci) = -3.36, -0.87) and aspartate aminotransferase (ast) (mean difference = -1.50, 95% ci = -2.59, -0.42). |
2024-09-30 |
2024-10-02 |
human |
| Ilaria Giangrandi, Monica Dinu, Antonia Napoletano, Valentina Maggini, Niccolò Lombardi, Giada Crescioli, Eugenia Gallo, Vittorio Mascherini, Michele Antonelli, Davide Donelli, Alfredo Vannacci, Fabio Firenzuoli, Francesco Sof. Licorice and liver function in patients with primary liver disease: A systematic review and meta-analysis of RCTs. Phytotherapy research : PTR. 2024-07-30. PMID:39079711. |
licorice significantly reduced alanine aminotransferase (alt) by 15.63 u/l (95% ci: -25.08, -6.18; p = 0.001) and aspartate aminotransferase (ast) by 7.37 u/l (95% ci: -13.13, -1.61; p = 0.01) compared to control groups. |
2024-07-30 |
2024-08-02 |
human |
| Claudius Mayer, Till Ittermann, Sabine Schipf, Stefan Gross, Simon Kim, Jan Schielke, Robin Bülow, Jens-Peter Kühn, Markus M Lerch, Henry Völzke, Stephan Burkhard Felix, Martin Bahls, Giovanni Targher, Marcus Dörr, Marcello Ricardo Paulista Marku. Lower muscular strength is associated with greater liver fat content and higher serum liver enzymes-"The Sedentary's Liver" The Study of Health in Pomerania. European journal of sport science. vol 24. issue 6. 2024-06-14. PMID:38874978. |
specifically, a 10-kg lower hgs was associated with a 0.59% (95% confidence interval [ci]: 0.24-0.94; p = 0.001) higher lfc, a 0.051 µkatal/l (95% ci: 0.005-0.097; p = 0.031) higher gamma-glutamyltransferase (ggt) concentration and a 0.010 µkatal/l (95% ci: 0.001-0.020; p = 0.023) higher aspartate aminotransferase (ast) concentration. |
2024-06-14 |
2024-06-16 |
human |
| Mengyang Yu, Chengying Zhang, Sitong Wan, Yang Lu, Yufei Wang, Ting Liu, Huimin Wang, Wei Chen, Yahua Li. NEW PREDICTIVE BIOMARKERS FOR SCREENING COVID-19 PATIENTS WITH RHABDOMYOLYSIS IN COMBINATION WITH CYSTATIN C. Shock (Augusta, Ga.). vol 61. issue 4. 2024-04-11. PMID:38010067. |
multivariate analysis revealed that sao 2 (hazard ratio [hr], 0.946; 95% confidence interval [ci], 0.906-0.987; p = 0.011), cysc (hr, 2.124; 95% ci, 1.223-3.689; p = 0.008), aspartate aminotransferase (ast) (hr, 1.009; 95% ci, 1.000-1.018; p = 0.041), and hypersensitive c-reactive protein (hr, 1.005; 95% ci, 1.000-1.010; p = 0.045) were significantly associated with survivals. |
2024-04-11 |
2024-04-14 |
human |
| Chun Zhang, Feng Lin, Deng-Fang Guo, Qing-Lin Wang, De-Xian Xiao, Jian-Yuan Lin, Shi Che. Assessing the causal link between liver function and acute pancreatitis: A Mendelian randomisation study. PloS one. vol 19. issue 4. 2024-04-08. PMID:38578756. |
conversely, the results for alkaline phosphatase (alp) (or = 0.997, 95%ci: 0.992-1.002, p = 0.197) and aspartate aminotransferase (ast) (or = 0.939, 95%ci: 0.794-1.111, p = 0.464) did not show a causal effect on acute pancreatitis. |
2024-04-08 |
2024-04-10 |
Not clear |
| Yuansong Zhuang, Quanxu An, Fuhang Wang, Dongjian Han, Zhentao Qiao, Qingjiao Jiang, Miaomiao Liu, Yuhang Li, Jiahong Shangguan, Xuanye Bi, Deliang She. The role of circulating biomarkers in predicting the 30-day mortality of immune checkpoint inhibitors-related myocarditis: a retrospective cohort study. Internal and emergency medicine. 2023-12-12. PMID:38085435. |
after adjusting for potential confounding factors using multivariate analysis tools, we demonstrated the excellent performance of biomarkers in predicting 30-day mortality in patients with icis-m, including plt (hazard ratio (hr), 1.07; 95% confidence interval (95%ci), 1.01-1.14; p = 0.028), alt (hr, 1.23; 95%ci, 1.06-1.41; p = 0.005), ast(hr, 1.06; 95%ci, 1.01-1.10; p = 0.015), ldh (hr, 1.15; 95%ci, 1.04-1.26; p = 0.004), troponin i(hr, 1.44; 95%ci, 1.09-1.89; p = 0.009), plr (blood plate/lymphocyte) (hr, 1.04; 95% ci, 1.01-1.07; p = 0.024), lar (lactate dehydrogenase/albumin) (hr, 1.05; 95%ci, 1.01-1.09; p = 0.012), and aar (aspartate transaminase/albumin) (hr, 1.18; 95%ci, 1.00-1.39; p = 0.048). |
2023-12-12 |
2023-12-17 |
Not clear |
| Mi Dai, Lei Luo, Caiyan Xie, Zhongbao Chen, Mingzhe Zhang, Yan Xie, Xuejun Shang, Xubo Shen, Kunming Tian, Yuanzhong Zho. Single and Joint Associations of Polycyclic Aromatic Hydrocarbon Exposure with Liver Function during Early Pregnancy. Toxics. vol 11. issue 10. 2023-10-27. PMID:37888713. |
we found that each 1% increment of urinary 2-hydroxyphenanthrene (2-oh-phe) was associated with 3.36% (95% ci: 0.40%, 6.40%) higher alanine aminotransferase (alt) and 2.22% (95% ci: 0.80%, 3.67%) higher aspartate aminotransferase (ast). |
2023-10-27 |
2023-11-08 |
Not clear |
| Stamatina Vogli, Androniki Naska, Georgios Marinos, Maria-Iosifina Kasdagli, Philippos Orfano. The Effect of Vitamin E Supplementation on Serum Aminotransferases in Non-Alcoholic Fatty Liver Disease (NAFLD): A Systematic Review and Meta-Analysis. Nutrients. vol 15. issue 17. 2023-09-09. PMID:37686767. |
regarding aspartate aminotransferase (ast), patients in the experimental group experienced a reduction in serum levels, though smaller in absolute values [ast md = -4.65 iu/l, 95% ci (-7.44, -1.86) in studies conducted in asian populations] and of lower precision in non-asian studies [md = -5.60 iu/l, 95% ci (-11.48, 0.28)]. |
2023-09-09 |
2023-10-07 |
Not clear |
| Boya Zhang, Ying Zhou, Junyu Gu. Association of volatile methylsiloxanes exposure with non-alcoholic fatty liver disease among Chinese adults. Environmental pollution (Barking, Essex : 1987). 2023-07-03. PMID:37399934. |
with per doubling increase in the total cvmss, we observed a 1.40 (95%ci: 0.31, 2.48) increase in alanine aminotransferase (alt), a 1.56 (95%ci: 0.52, 2.61) increase in aspartate aminotransferase (ast) and a 0.04 (0.00, 0.09) increase in nafld index. |
2023-07-03 |
2023-08-14 |
human |
| Jennifer Kang, Harishankar Gopakumar, Srinivas R Pul. Prevalence of Osteoporosis in Cirrhosis: A Systematic Review and Meta-Analysis. Cureus. vol 15. issue 1. 2023-02-15. PMID:36788896. |
pooled levels of liver biochemistries were: bilirubin 3.04 mg/dl (95% ci: 2.84-3.25), aspartate aminotransferase (ast) 65.35 u/l (95% ci: 61.39-69.31), alanine aminotransferase (alt) 50.17 u/l (95% ci: 46.18-54.10), alkaline phosphatase 133.31 u/l (95% ci: 124.89-141.73), and albumin 3.25 g/dl (95% ci: 3.05-3.45). |
2023-02-15 |
2023-08-14 |
Not clear |
| Yixi Zhang, Jingyuan Wang, Taobo Hu, Huina Wang, Mengping Long, Baosheng Lian. Adverse Events of PD-1 or PD-L1 Inhibitors in Triple-Negative Breast Cancer: A Systematic Review and Meta-Analysis. Life (Basel, Switzerland). vol 12. issue 12. 2022-12-23. PMID:36556355. |
for non-serious adverse events, the patients treated with pd-1 or pd-l1 inhibitors had higher risk of aspartate aminotransferase (ast) elevation (or =1.26, 95%ci: 1.02-1.57), hypothyroidism (or = 3.63, 95%ci: 2.92-4.51), pruritus (or = 1.84, 95%ci: 1.30-2.59), rash (or = 1.29, 95%ci: 1.08-1.55), and fever (or = 1.77, 95%ci: 1.13-2.77), compared with chemotherapy alone. |
2022-12-23 |
2023-08-14 |
Not clear |
| Feng-Jing-Ming Cheng, Jian Lyu, Yan-Ming Xi. [Systematic review and Meta-analysis of efficacy and safety of Ganshuang Granules in treatment of liver injury]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 21. 2022-12-06. PMID:36472014. |
the results of meta-analysis showed that ganshuang granules combined with conventional therapy was superior to the therapy in the control group in reducing alanine aminotransferase(alt)(md=-24.12, 95%ci[-32.17,-16.07], p<0.000 01), aspartate aminotransferase(ast)(md=-23.24, 95%ci[-29.70,-16.78], p<0.000 01), total bilirubin(tbil)(md=-12.42, 95%ci[-14.62,-10.22], p<0.000 01), and gamma-glutamyl transpeptidase(ggt)(md=-21.32, 95%ci[-33.61,-9.03], p=0.000 7). |
2022-12-06 |
2023-08-14 |
Not clear |
| Jin-Cheng Tian, Hui Liu, Lun-Jie Yan, Zi-Niu Ding, Cheng-Long Han, Bao-Wen Tian, Si-Yu Tan, Zhao-Ru Dong, Dong-Xu Wang, Jun-Shuai Xue, Xin-Cheng Mao, Yu-Chuan Yan, Tao L. Adverse events of immune checkpoint inhibitors in hepatocellular carcinoma: a systemic review and meta-analysis. Clinical and experimental medicine. 2022-11-17. PMID:36385419. |
aspartate aminotransferase (ast) increase (38%, 95% ci 35-40%) is the most common traes. |
2022-11-17 |
2023-08-14 |
Not clear |
| Mohammad Reza Amini, Fatemeh Sheikhhossein, Alireza Talebyan, Elham Bazshahi, Farhang Djafari, Azita Hekmatdoos. Effects of Artichoke Supplementation on Liver Enzymes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Clinical nutrition research. vol 11. issue 3. 2022-08-11. PMID:35949559. |
pooled analysis of seven randomized controlled trials (rcts) suggested that the artichoke administration has an effect on both alanine aminotransferase (alt) (hedges' g, -1.08; 95% confidence interval [ci], -1.76 to -0.40; p = 0.002), and aspartate aminotransferase (ast) (hedges' g, -1.02; 95% ci, -1.76 to -0.28; p = 0.007). |
2022-08-11 |
2023-08-14 |
Not clear |
| Basma S Ismail, Basant Mahmoud, Eman S Abdel-Reheim, Hanan A Soliman, Tarek M Ali, Basem H Elesawy, Mohamed Y Zak. Cinnamaldehyde Mitigates Atherosclerosis Induced by High-Fat Diet Oxidative medicine and cellular longevity. vol 2022. 2022-07-01. PMID:35774377. |
moreover, ci reduced the elevated serum creatine kinase (ck), creatine kinase-mb (ck-mb), lactate dehydrogenase (ldh), and aspartate aminotransferase (ast) activities. |
2022-07-01 |
2023-08-14 |
rat |
| Mukharram M Bikbov, Timur R Gilmanshin, Rinat M Zainullin, Gyulli M Kazakbaeva, Ellina M Iakupova, Albina A Fakhretdinova, Azaliia M Tuliakova, Songhomitra Panda-Jonas, Leisan I Gilemzianova, Dinar A Khakimov, Liana A Miniazeva, Jost B Jona. Prevalence of non-alcoholic fatty liver disease in the Russian Ural Eye and Medical Study and the Ural Very Old Study. Scientific reports. vol 12. issue 1. 2022-05-13. PMID:35551494. |
defining nafld by an absence of regular alcohol consumption, and by abnormally high alanine transaminase (alt) and aspartate transaminase (ast) concentrations or an ast/alt ratio of > 1.0, 2341 out of 5852 uems participants (40.0%; 95% confidence intervals (ci) 38.8, 41.3) had nafld. |
2022-05-13 |
2023-08-13 |
human |
| Catalina M Mascaró, Cristina Bouzas, Sofia Montemayor, Miguel Casares, Cristina Gómez, Lucía Ugarriza, Pere-Antoni Borràs, José Alfredo Martínez, Josep A Tu. Association between Physical Activity and Non-Alcoholic Fatty Liver Disease in Adults with Metabolic Syndrome: The FLIPAN Study. Nutrients. vol 14. issue 5. 2022-03-14. PMID:35268038. |
pa was a risk factor for ast (aspartate aminotransferase) (adjusted or: 7.26; 95% ci: 1.79−29.40) and a protective factor for alt (alanine aminotransferase) (adjusted or: 0.24; 95% ci: 0.12−0.48), ggt (gamma-glutamyl transferase) (adjusted or: 0.52; 95% ci: 0.29−0.94) and ifc-nmr (intrahepatic fat content by nuclear magnetic resonance) (adjusted or: 0.26; 95% ci: 0.12−0.56) when sociodemographic confounders were considered. |
2022-03-14 |
2023-08-16 |
human |
| Sabit Cakmak, Anna Lukina, Subramanian Karthikeyan, Ella Atlas, Robert Dale. The association between blood PFAS concentrations and clinical biochemical measures of organ function and metabolism in participants of the Canadian Health Measures Survey (CHMS). The Science of the total environment. 2022-02-26. PMID:35218824. |
an increase in perfluorooctanoic acid (pfoa) equivalent to the magnitude of its geometric mean (gm) of 2.0 μg/l was associated with percentage (95% ci) increases in serum enzymes reflecting liver function: aspartate aminotransferase (ast) 3.7 (1.1, 6.4), gamma-glutamyl transferase (ggt) 11.8 (2.5, 21.8), alanine aminotransferase (alt) 3.2 (0.5, 5.9), and bilirubin 3.6 (2.7, 4.5). |
2022-02-26 |
2023-08-13 |
human |
| Mahmoud A Khattab, Yehia Zakaria, Eslam Sadek, Aliaa S Abd El Fatah, Magdy Fouad, Muhammed Khattab, Hend M Moness, Nashwa Mohamed Adel, Elham Ahme. Detection of hepatitis C virus (HCV) RNA in the peripheral blood mononuclear cells of HCV-infected patients following sustained virologic response. Clinical and experimental medicine. 2022-01-23. PMID:35066710. |
multiple logistic regression analysis showed that only the higher posttreatment levels of aspartate transaminase (ast) were significantly predictive of hcv rna persistence in the pbmcs (or: 1.29; 95% ci: 1.08-1.55). |
2022-01-23 |
2023-08-13 |
Not clear |
| Mahshid Mostafavi, Iraj Sharifi, Gholamreza Asadikaram, Nozar Nakhaee, Sina Kakooei, Mohammad Reza Aflatoonian, Mehdi Bamorovat, Razieh Tavakoli Oliaee, Ali Karamoozia. The impact of diabetes on cutaneous leishmaniasis: a case-control field assessment. Parasitology research. vol 120. issue 11. 2021-11-25. PMID:34604933. |
data analysis showed that six major risk factors, including female (odds ratio (or) = 3.47, confidence interval (ci) = 1.84-6.53, p < 0.001), total protein in cl group (or = 4.9, ci = 2.3-10.44, p < 0.001), alanine aminotransferase (alt) concentration in cl group (or = 0.87, ci = 0.81-0.93, p < 0.001) and dm co-infected with cl group (or = 0.8, ci = 0.72-0.88, p < 0.001) than healthy group, aspartate aminotransferase (ast) concentration in dm group (or = 0.86, ci = 0.76-0.98, p = 0.02), transforming growth factor beta)tgf-β( level in the cl group (or = 1.03, ci = 1.003-1.05, p = 0.02), and presence of diabetes disease (or = 2.07, ci = 1.16-3.7, p < 0.05), were significantly linked with the induction of cl lesion. |
2021-11-25 |
2023-08-13 |
human |