All Relations between arrb2 and insulin
| Publication | Sentence | Publish Date | Extraction Date | Species |
|---|---|---|---|---|
| Nour Za\\xc3\\xafmia, Joelle Obeid, Annie Varrault, Julia Sabatier, Christophe Broca, Patrick Gilon, Safia Costes, Gyslaine Bertrand, Magalie A Ravie. GLP-1 and GIP receptors signal through distinct \\xce\\xb2-arrestin 2-dependent pathways to regulate pancreatic \\xce\\xb2 cell function. Cell reports. vol 42. issue 11. 2023-10-28. PMID:37897727. | in contrast, gip-potentiated insulin secretion needs arrb2 in mouse and human islets. | 2023-10-28 | 2023-11-08 | mouse |
| Nour Za\\xc3\\xafmia, Joelle Obeid, Annie Varrault, Julia Sabatier, Christophe Broca, Patrick Gilon, Safia Costes, Gyslaine Bertrand, Magalie A Ravie. GLP-1 and GIP receptors signal through distinct \\xce\\xb2-arrestin 2-dependent pathways to regulate pancreatic \\xce\\xb2 cell function. Cell reports. vol 42. issue 11. 2023-10-28. PMID:37897727. | in mouse \xce\xb2 cells, arrb2 dampens insulin secretion by partially uncoupling cyclic amp (camp)/protein kinase a (pka) signaling at physiological doses of glp-1, whereas at pharmacological doses, the activation of extracellular signal-related kinase (erk)/camp-responsive element-binding protein (creb) requires arrb2. | 2023-10-28 | 2023-11-08 | mouse |
| Nour Za\\xc3\\xafmia, Joelle Obeid, Annie Varrault, Julia Sabatier, Christophe Broca, Patrick Gilon, Safia Costes, Gyslaine Bertrand, Magalie A Ravie. GLP-1 and GIP receptors signal through distinct \\xce\\xb2-arrestin 2-dependent pathways to regulate pancreatic \\xce\\xb2 cell function. Cell reports. vol 42. issue 11. 2023-10-28. PMID:37897727. | finally, the dual glp-1/gip agonist tirzepatide does not require arrb2 for the potentiation of insulin secretion. | 2023-10-28 | 2023-11-08 | mouse |