| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fuwei Zhang, Ines Armando, Pedro A Jose, Chunyu Zeng, Jian Yan. G protein-coupled receptor kinases in hypertension: physiology, pathogenesis, and therapeutic targets. Hypertension research : official journal of the Japanese Society of Hypertension. 2024-07-03. PMID:38961282. |
in organs such as the artery and kidney, hormones or neurotransmitters, such as angiotensin ii (ang ii), dopamine, epinephrine, and norepinephrine exert their functions via their receptors, with the ultimate effect of keeping normal vascular reactivity, normal body sodium, and normal blood pressure. |
2024-07-03 |
2024-07-10 |
Not clear |
| Fuwei Zhang, Ines Armando, Pedro A Jose, Chunyu Zeng, Jian Yan. G protein-coupled receptor kinases in hypertension: physiology, pathogenesis, and therapeutic targets. Hypertension research : official journal of the Japanese Society of Hypertension. 2024-07-03. PMID:38961282. |
in particular, increasing number of studies show that aberrant expression and activity of grks in the cardiovascular system and kidney inhibit or stimulate gpcrs (e.g., dopamine receptors, ang ii receptors, and α- and β-adrenergic receptors), resulting in hypertension. |
2024-07-03 |
2024-07-10 |
Not clear |
| Erin M Leonard, Colin A Nurs. The Carotid Body "Tripartite Synapse": Role of Gliotransmission. Advances in experimental medicine and biology. vol 1427. 2023-06-15. PMID:37322349. |
during chemotransduction, type i cells depolarize and release a multitude of excitatory and inhibitory neurotransmitters/neuromodulators including atp, dopamine (da), histamine, and angiotensin ii (ang ii). |
2023-06-15 |
2023-08-14 |
Not clear |
| Nicolás M Kouyoumdzian, Natalia L Rukavina Mikusic, Gabriel D Robbesaul, Susana B Gorzalczany, Andrea Carranza, Verónica Trida, Belisario E Fernández, Marcelo R Cho. Acute infusion of angiotensin II regulates organic cation transporters function in the kidney: its impact on the renal dopaminergic system and sodium excretion. Hypertension research : official journal of the Japanese Society of Hypertension. vol 44. issue 3. 2021-07-22. PMID:32934369. |
our aim was to study whether renal dopamine and ang ii can interact to modify renal sodium handling and then to elucidate the related mechanism. |
2021-07-22 |
2023-08-13 |
rat |
| Nicolás M Kouyoumdzian, Natalia L Rukavina Mikusic, Gabriel D Robbesaul, Susana B Gorzalczany, Andrea Carranza, Verónica Trida, Belisario E Fernández, Marcelo R Cho. Acute infusion of angiotensin II regulates organic cation transporters function in the kidney: its impact on the renal dopaminergic system and sodium excretion. Hypertension research : official journal of the Japanese Society of Hypertension. vol 44. issue 3. 2021-07-22. PMID:32934369. |
ang ii, exogenous dopamine, and decynium-22 (or d-22, an isocyanine that specifically blocks electrogenic organic cation transporters, octs), were infused in vivo for 120 min. |
2021-07-22 |
2023-08-13 |
rat |
| Chengping Luo, Huimin Fan, Shaojun Li, Yuling Zo. Therapeutic of Candesartan and Music Therapy in Diabetic Retinopathy with Depression in Rats. Evidence-based complementary and alternative medicine : eCAM. vol 2021. 2021-04-10. PMID:33833815. |
angiotensin ii (ang ii) in peripheral blood and neurotransmitters, including serotonin (5-ht), dopamine (da), and norepinephrine (ne) in the hippocampus, was measured by enzyme linked immunosorbent assay (elisa). |
2021-04-10 |
2023-08-13 |
rat |
| Mostafa A Rabie, Mai A Abd El Fattah, Noha N Nassar, Dalaal M Abdallah, Hanan S El-Abha. Correlation between angiotensin 1-7-mediated Mas receptor expression with motor improvement, activated STAT3/SOCS3 cascade, and suppressed HMGB-1/RAGE/NF-κB signaling in 6-hydroxydopamine hemiparkinsonian rats. Biochemical pharmacology. vol 171. 2020-07-27. PMID:31669235. |
this correlation extends to involve other effects of ang 1-7, such as the increased striatal dopamine content (r = 0.98, p = 0.0005), substantia nigra pars compacta tyrosine hydroxylase immune-reactivity (r = 0.97, p = 0.001), active py705-stat3 (r = 0.99, p < 0.0001) and socs3 (r = 0.99, p < 0.0001). |
2020-07-27 |
2023-08-13 |
rat |
| Armaz Aschrafi, Adama Berndt, Jeffrey A Kowalak, Jenna R Gale, Anthony E Gioio, Barry B Kapla. Angiotensin II mediates the axonal trafficking of tyrosine hydroxylase and dopamine β-hydroxylase mRNAs and enhances norepinephrine synthesis in primary sympathetic neurons. Journal of neurochemistry. vol 150. issue 6. 2020-03-23. PMID:31306490. |
in the present study, the hypothesis was tested that ang ii induces ne synthesis in rat primary scg neurons via the modulation of the trafficking of the mrnas encoding the catecholamine synthesizing enzymes th and dopamine β-hydroxylase (dbh). |
2020-03-23 |
2023-08-13 |
rat |
| Rosilane Taveira-da-Silva, Luzia da Silva Sampaio, Adalberto Vieyra, Marcelo Einicker-Lama. L-Tyr-Induced Phosphorylation of Tyrosine Hydroxylase at Ser40: An Alternative Route for Dopamine Synthesis and Modulation of Na+/K+-ATPase in Kidney Cells. Kidney & blood pressure research. vol 44. issue 1. 2019-04-22. PMID:30808844. |
dopamine (da) is a natriuretic hormone that inhibits renal sodium reabsorption, being angiotensin ii (ang ii) its powerful counterpart. |
2019-04-22 |
2023-08-13 |
Not clear |
| Osvaldo Martin Basmadjian, Victoria Belen Occhieppo, Natalia Andrea Marchese, Gustavo Baiardi, Claudia Bregonzi. Brain Angiotensin II Involvement in Chronic Mental Disorders. Protein and peptide letters. vol 24. issue 9. 2018-08-21. PMID:28758591. |
little is known about schizophrenia and ras; however, ang ii is closely related to dopamine and glutamate pathways, which are mainly altered in this pathology. |
2018-08-21 |
2023-08-13 |
Not clear |
| Dominik Wincewicz, Jan J Braszk. Validation of Brain Angiotensin System Blockade as a Novel Drug Target in Pharmacological Treatment of Neuropsychiatric Disorders. Pharmacopsychiatry. vol 50. issue 6. 2018-08-14. PMID:28641333. |
recent findings implicate brain ras, especially angiotensin ii (ang ii), in neural pathophysiology of mental disorders through neuroendocrine modulation and effects on neurotransmitter release, mostly noradrenaline, acetylcholine and dopamine. |
2018-08-14 |
2023-08-13 |
Not clear |
| Tarek K Motawi, Hebatallah A Darwish, Manal A Hamed, Nagy S El-Rigal, Asmaa F Aboul Nase. A Therapeutic Insight of Niacin and Coenzyme Q10 Against Diabetic Encephalopathy in Rats. Molecular neurobiology. vol 54. issue 3. 2018-02-07. PMID:26867655. |
the evaluation was done through the estimation of the levels of blood glucose, serum insulin, and oxidative stress markers: malondialdehyde (mda), superoxide dismutase (sod), and glutathione (gsh); neurotransmitters: acetylcholinesterase (ache) and dopamine (da); vasoconstrictor indices: intercellular adhesion molecule-1 (icam-1), vascular cell adhesion molecule-1(vcam-1), and angiotensin ii (ang ii); and apoptosis markers: tumor necrosis factor-α (tnf-α) and caspase-3 as well as the histopathological picture of the cerebellum region of the brain. |
2018-02-07 |
2023-08-13 |
rat |
| Jürgen M Bohlender, Jürg Nussberger, Frédéric Birkhäuser, Eric Grouzmann, George N Thalmann, Hans Imbode. Resetting of renal tissular renin-angiotensin and bradykinin-kallikrein systems after unilateral kidney denervation in rats. Histochemistry and cell biology. vol 147. issue 5. 2018-01-12. PMID:28220244. |
renin, ang iii and dopamine concentrations decreased by ~25 to 50% and norepinephrine concentrations by 99% in dnx kidneys (p < 0.05) but were unaltered in opposite kidneys. |
2018-01-12 |
2023-08-13 |
rat |
| Negar Firouzabadi, Nima Ghazanfari, Ali Alavi Shoushtari, Nasrallah Erfani, Farshid Fathi, Mozhdeh Bazrafkan, Ehsan Bahramal. Genetic Variants of Angiotensin-Converting Enzyme Are Linked to Autism: A Case-Control Study. PloS one. vol 11. issue 4. 2016-09-06. PMID:27082637. |
the importance of renin-angiotensin system (ras) elements in cognition and behavior besides the interaction of angiotensin ii (ang ii), the main product of angiotensin-converting enzyme (ace), with neurotransmitters in cns, especially dopamine, proposes the involvement of ras in autism. |
2016-09-06 |
2023-08-13 |
Not clear |
| Changqing Yu, Jianghua Chen, Weiwei Guan, Yu Han, Wei Eric Wang, Xukai Wang, Hongyong Wang, Pedro A Jose, Chunyu Zen. Activation of the D4 dopamine receptor attenuates proliferation and migration of vascular smooth muscle cells through downregulation of AT1a receptor expression. Hypertension research : official journal of the Japanese Society of Hypertension. vol 38. issue 9. 2016-06-07. PMID:25832920. |
angiotensin (ang) ii has an important role in the vascular smooth muscle cell (vsmc) proliferation and migration and subsequently in the development of vascular diseases, whereas dopamine has the opposite effect. |
2016-06-07 |
2023-08-13 |
rat |
| A P Seale, Y Yamaguchi, W M Johnstone, R J Borski, D T Lerner, E G Gra. Endocrine regulation of prolactin cell function and modulation of osmoreception in the Mozambique tilapia. General and comparative endocrinology. vol 192. 2014-06-10. PMID:23722201. |
prolactin release has been shown to be stimulated by gonadotropin-releasing hormone (gnrh), 17-β-estradiol (e2), testosterone (t), thyrotropin-releasing hormone (trh), atrial natriuretic peptide (anp), brain-natriuretic peptide (bnp), c-type natriuretic peptide (cnp), ventricular natriuretic peptide (vnp), prl-releasing peptide (prrp), angiotensin ii (ang ii), leptin, insulin-like growth factors (igfs), ghrelin, and inhibited by somatostatin (ss), urotensin-ii (u-ii), dopamine, cortisol, ouabain and vasoactive intestinal peptide (vip). |
2014-06-10 |
2023-08-12 |
Not clear |
| Donglin Zhu, Qiang Tong, Wei Liu, Minjie Tian, Wei Xie, Li Ji, Jingping Sh. Angiotensin (1-7) protects against stress-induced gastric lesions in rats. Biochemical pharmacology. vol 87. issue 3. 2014-03-28. PMID:24231511. |
brain ang (1-7) administration profoundly modified responses to stress, indicated by altered levels of several stress hormones, including ang ii, glucocorticoid, norepinephrine, serotonin, and dopamine, in blood or stress-related brain regions. |
2014-03-28 |
2023-08-12 |
rat |
| Regina Nostramo, Andrej Tillinger, Juan M Saavedra, Ashok Kumar, Varunkumar Pandey, Lidia Serova, Richard Kvetnansky, Esther L Sabba. Regulation of angiotensin II type 2 receptor gene expression in the adrenal medulla by acute and repeated immobilization stress. The Journal of endocrinology. vol 215. issue 2. 2013-01-03. PMID:22911895. |
these effects of stress on ang ii receptor expression may alter catecholamine biosynthesis, as tyrosine hydroxylase and dopamine β-hydroxylase mrna levels in pc12 cells are decreased with ang ii treatment in the presence of zd7155 (at(1) receptor antagonist) or with cgp42112 (at(2) receptor agonist) treatment. |
2013-01-03 |
2023-08-12 |
mouse |
| E Loyens, A Schallier, S Y Chai, D De Bundel, P Vanderheyden, Y Michotte, I Smolder. Deletion of insulin-regulated aminopeptidase in mice decreases susceptibility to pentylenetetrazol-induced generalized seizures. Seizure. vol 20. issue 8. 2012-06-18. PMID:21612947. |
it has been hypothesized that the latter effects on seizures could be established via a modulatory effect on dopamine receptors in the basal ganglia or via an indirect interaction between ang iv and adenosine a1 receptors. |
2012-06-18 |
2023-08-12 |
mouse |
| Shilin Yang, Bing Yao, Yunfeng Zhou, Huiyong Yin, Ming-Zhi Zhang, Raymond C Harri. Intrarenal dopamine modulates progressive angiotensin II-mediated renal injury. American journal of physiology. Renal physiology. vol 302. issue 6. 2012-05-09. PMID:22169008. |
previous studies by us and others have indicated that dopamine may modulate actions of ang ii in the kidney. |
2012-05-09 |
2023-08-12 |
mouse |