| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D R Smith, S T Lim, S J X Murphy, F B Hickey, C Offiah, S M Murphy, D R Collins, T Coughlan, D O'Neill, B Egan, J S O'Donnell, J M O'Sullivan, D J H McCab. von Willebrand factor antigen, von Willebrand factor propeptide and ADAMTS13 activity in TIA or ischaemic stroke patients changing antiplatelet therapy. Journal of the neurological sciences. vol 463. 2024-07-18. PMID:39024743. |
data are limited on the impact of commencing antiplatelet therapy on von willebrand factor antigen (vwf:ag) or von willebrand factor propeptide (vwfpp) levels and adamts13 activity, and their relationship with platelet reactivity following tia/ischaemic stroke. |
2024-07-18 |
2024-07-21 |
Not clear |
| D R Smith, S T Lim, S J X Murphy, F B Hickey, C Offiah, S M Murphy, D R Collins, T Coughlan, D O'Neill, B Egan, J S O'Donnell, J M O'Sullivan, D J H McCab. von Willebrand factor antigen, von Willebrand factor propeptide and ADAMTS13 activity in TIA or ischaemic stroke patients changing antiplatelet therapy. Journal of the neurological sciences. vol 463. 2024-07-18. PMID:39024743. |
in this pilot, observational study, vwf:ag and vwfpp levels and adamts13 activity were quantified in 48 patients ≤4 weeks of tia/ischaemic stroke (baseline), and 14 days (14d) and 90 days (90d) after commencing aspirin, clopidogrel or aspirin+dipyridamole. |
2024-07-18 |
2024-07-21 |
Not clear |
| Nikolay V Goncharov, Polina I Popova, Igor V Kudryavtsev, Alexey S Golovkin, Irina V Savitskaya, Piotr P Avdonin, Ekaterina A Korf, Natalia G Voitenko, Daria A Belinskaia, Maria K Serebryakova, Natalia V Matveeva, Natalia O Gerlakh, Natalia E Anikievich, Marina A Gubatenko, Irina A Dobrylko, Andrey S Trulioff, Arthur D Aquino, Richard O Jenkins, Pavel V Avdoni. Immunological Profile and Markers of Endothelial Dysfunction in Elderly Patients with Cognitive Impairments. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38339164. |
the non-specific deviations were for the moca (montreal cognitive impairment scale), the mmse (mini mental state examination) and life satisfaction self-assessment scores, a decrease of albumin levels, and adamts13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13) activity, and an increase of the vwf (von willebrand factor) level. |
2024-02-10 |
2024-02-12 |
Not clear |
| Felix S Seibert, Arturo Blazquez-Navarro, Bodo Hölzer, Adrian A N Doevelaar, Christian Nusshag, Uta Merle, Christian Morath, Panagiota Zgoura, Rita Dittmer, Sonja Schneppenheim, Jochen Wilhelm, Nina Babel, Ulrich Budde, Timm H Westhof. Effect of plasma exchange on COVID-19 associated excess of von Willebrand factor and inflammation in critically ill patients. Scientific reports. vol 12. issue 1. 2022-03-22. PMID:35314740. |
vwf antigen (vwf:ag), adamts13 activity, a cytokine panel mirroring the inflammatory situation and clinical parameters were assessed before and after three to six plex therapies with fresh frozen plasma. |
2022-03-22 |
2023-08-13 |
Not clear |
| Stephen J X Murphy, Soon Tjin Lim, Fionnuala Hickey, Justin A Kinsella, Deirdre R Smith, Sean Tierney, Bridget Egan, T Martin Feeley, Sinéad M Murphy, D Rónán Collins, Tara Coughlan, Desmond O'Neill, Joseph A Harbison, Prakash Madhavan, Sean M O'Neill, Mary-Paula Colgan, James S O'Donnell, Jamie M O'Sullivan, George Hamilton, Dominick J H McCab. von Willebrand Factor Antigen, von Willebrand Factor Propeptide, and ADAMTS13 in Carotid Stenosis and Their Relationship with Cerebral Microemboli. Thrombosis and haemostasis. vol 121. issue 1. 2021-07-02. PMID:32932544. |
the relationship between von willebrand factor antigen (vwf:ag), vwf propeptide (vwfpp), vwfpp/vwf:ag ratio, adamts13 activity, and microembolic signal (mes) status in carotid stenosis is unknown. |
2021-07-02 |
2023-08-13 |
Not clear |
| Anne-Sophie Putzer, Hans Worthmann, Gerrit M Grosse, Friedrich Goetz, Jens Martens-Lobenhoffer, Meike Dirks, Jan T Kielstein, Ralf Lichtinghagen, Ulrich Budde, Stefanie M Bode-Böger, Karin Weissenborn, Ramona Schuppne. ADAMTS13 activity is associated with early neurological improvement in acute ischemic stroke patients treated with intravenous thrombolysis. Journal of thrombosis and thrombolysis. vol 49. issue 1. 2020-10-06. PMID:31482326. |
we hypothesized that pretreatment levels of mediators of hemostasis (vwf and adamts13) and dimethylarginines (adma and sdma) are associated with early neurological improvement and outcome after ivt in ischemic stroke. |
2020-10-06 |
2023-08-13 |
Not clear |
| Alice Taylor, Chiara Vendramin, Deepak Singh, Martin M Brown, Marie Scull. von Willebrand factor/ADAMTS13 ratio at presentation of acute ischemic brain injury is predictive of outcome. Blood advances. vol 4. issue 2. 2020-07-20. PMID:31990334. |
acute ischemic stroke (is) and transient ischemic attack (tia) are associated with raised von willebrand factor (vwf) and decreased adamts13 activity (adamts13ac). |
2020-07-20 |
2023-08-13 |
Not clear |
| A C van Dijk, S J Donkel, T Zadi, M A H Sonneveld, F H B M Schreuder, M F Chohan, P J Koudstaal, F W G Leebeek, R Saxena, J Hendrikse, M E Kooi, A van der Lugt, M P M de Maa. Association between fibrinogen and fibrinogen γ' and atherosclerotic plaque morphology and composition in symptomatic carotid artery stenosis: Plaque-At-RISK study. Thrombosis research. vol 177. 2020-01-06. PMID:30897531. |
von willebrand factor (vwf), adamts13, fibrinogen and fibrinogen γ' are associated with an increased risk of ischemic stroke. |
2020-01-06 |
2023-08-13 |
Not clear |
| Frank J Wolters, Johan Boender, Paul S de Vries, Michelle A Sonneveld, Peter J Koudstaal, Moniek P de Maat, Oscar H Franco, M Kamran Ikram, Frank W Leebeek, M Arfan Ikra. Von Willebrand factor and ADAMTS13 activity in relation to risk of dementia: a population-based study. Scientific reports. vol 8. issue 1. 2019-10-08. PMID:29615758. |
cardiovascular health is an important determinant of cognitive decline, but the association of either vwf or adamts13 with risk of dementia is unknown. |
2019-10-08 |
2023-08-13 |
human |
| Nina Buchtele, Michael Schwameis, James C Gilbert, Christian Schörgenhofer, Bernd Jilm. Targeting von Willebrand Factor in Ischaemic Stroke: Focus on Clinical Evidence. Thrombosis and haemostasis. vol 118. issue 6. 2019-09-30. PMID:29847840. |
(1) animal models which recapitulate the pathogenesis of stroke and validate the concept of targeting vwf for stroke prevention and the use of the vwf cleavage enzyme adamts13 in acute stroke treatment. |
2019-09-30 |
2023-08-13 |
Not clear |
| H Wan, Y Wang, J Ai, S Brathwaite, H Ni, R L Macdonald, E M Hol, J C M Meijers, M D I Vergouwe. Role of von Willebrand factor and ADAMTS-13 in early brain injury after experimental subarachnoid hemorrhage. Journal of thrombosis and haemostasis : JTH. vol 16. issue 7. 2019-09-16. PMID:29729651. |
essentials von willebrand factor (vwf) and adamts13 may affect early injury after subarachnoid hemorrhage (sah). |
2019-09-16 |
2023-08-13 |
Not clear |
| Vaclav Prochazka, Tomas Jonszta, Daniel Czerny, Jan Krajca, Martin Roubec, Jirka Macak, Petr Kovar, Petra Kovarova, Martin Pulcer, Renata Zoubkova, Ivo Lochman, Veronika Svachova, Lubomir Pavliska, Adela Vrtkova, David Kasprak, Jaromir Gumulec, John W Weise. The Role of von Willebrand Factor, ADAMTS13, and Cerebral Artery Thrombus Composition in Patient Outcome Following Mechanical Thrombectomy for Acute Ischemic Stroke. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2018-10-15. PMID:29887594. |
background the aim of the study was to investigate the role of von willebrand factor (vwf), the vwf-cleaving protease, adamts13, the composition of thrombus, and patient outcome following mechanical cerebral artery thrombectomy in patients with acute ischemic stroke. |
2018-10-15 |
2023-08-13 |
Not clear |
| Vaclav Prochazka, Tomas Jonszta, Daniel Czerny, Jan Krajca, Martin Roubec, Jirka Macak, Petr Kovar, Petra Kovarova, Martin Pulcer, Renata Zoubkova, Ivo Lochman, Veronika Svachova, Lubomir Pavliska, Adela Vrtkova, David Kasprak, Jaromir Gumulec, John W Weise. The Role of von Willebrand Factor, ADAMTS13, and Cerebral Artery Thrombus Composition in Patient Outcome Following Mechanical Thrombectomy for Acute Ischemic Stroke. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2018-10-15. PMID:29887594. |
patients with a national institutes of health stroke scale (nihss) score ≥15 had significantly increased vwf levels (p=0.003), and a significantly increased vwf: adamts13 ratio (p=0.038) on hospital admission. |
2018-10-15 |
2023-08-13 |
Not clear |
| W-H Li, C-J Hui, H J. Expression and significance of vWF, GMP-140 and ADAMTS13 in patients with aneurysmal subarachnoid hemorrhage. European review for medical and pharmacological sciences. vol 21. issue 19. 2018-07-16. PMID:29077161. |
expression and significance of vwf, gmp-140 and adamts13 in patients with aneurysmal subarachnoid hemorrhage. |
2018-07-16 |
2023-08-13 |
Not clear |
| Frederik Denorme, Peter Kraft, Inge Pareyn, Christiane Drechsler, Hans Deckmyn, Karen Vanhoorelbeke, Christoph Kleinschnitz, Simon F De Meye. Reduced ADAMTS13 levels in patients with acute and chronic cerebrovascular disease. PloS one. vol 12. issue 6. 2017-09-13. PMID:28591212. |
furthermore, when assessing the vwf:adamts13 ratios, an even greater difference was revealed between stroke patients (2.7 ± 1.9), hv (1.1 ± 0.5) and ccd patients (1.7 ± 0.7). |
2017-09-13 |
2023-08-13 |
human |
| Frederik Denorme, Peter Kraft, Inge Pareyn, Christiane Drechsler, Hans Deckmyn, Karen Vanhoorelbeke, Christoph Kleinschnitz, Simon F De Meye. Reduced ADAMTS13 levels in patients with acute and chronic cerebrovascular disease. PloS one. vol 12. issue 6. 2017-09-13. PMID:28591212. |
whereas increasing evidence shows a clear association between vwf levels and acute ischemic stroke, little is known about a correlation with adamts13. |
2017-09-13 |
2023-08-13 |
human |
| Frederik Denorme, Peter Kraft, Inge Pareyn, Christiane Drechsler, Hans Deckmyn, Karen Vanhoorelbeke, Christoph Kleinschnitz, Simon F De Meye. Reduced ADAMTS13 levels in patients with acute and chronic cerebrovascular disease. PloS one. vol 12. issue 6. 2017-09-13. PMID:28591212. |
the vwf:adamts13 ratio was significantly associated with stroke severity and modality. |
2017-09-13 |
2023-08-13 |
human |
| Haochen Xu, Yongliang Cao, Xing Yang, Ping Cai, Lijing Kang, Ximin Zhu, Haiyu Luo, Lu Lu, Lixiang Wei, Xiaofei Bai, Yuanbo Zhu, Bing-Qiao Zhao, Wenying Fa. ADAMTS13 controls vascular remodeling by modifying VWF reactivity during stroke recovery. Blood. vol 130. issue 1. 2017-08-17. PMID:28428179. |
adamts13 controls vascular remodeling by modifying vwf reactivity during stroke recovery. |
2017-08-17 |
2023-08-13 |
mouse |
| Le Qu, Miao Jiang, Wenjuan Qiu, Shiqi Lu, Yunxiao Zhao, Lijun Xia, Changgeng Ruan, Yiming Zha. Assessment of the Diagnostic Value of Plasma Levels, Activities, and Their Ratios of von Willebrand Factor and ADAMTS13 in Patients with Cerebral Infarction. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. vol 22. issue 3. 2016-11-14. PMID:25916953. |
we aimed to investigate the relationships between plasma levels of vwf and adamts13, their ratios, and the occurrence of cerebral infarction and to understand the roles of vwf and adamts13 in cerebral infarction. |
2016-11-14 |
2023-08-13 |
Not clear |
| Christopher J Lynch, David A Lan. N-linked glycan stabilization of the VWF A2 domain. Blood. vol 127. issue 13. 2016-08-15. PMID:26773038. |
substitution of the surface-exposed y1544 to aspartic acid is able to stabilize the domain in the absence of glycosylation and protect against adamts13 proteolysis in both the vwf a2 domain and flvwf. |
2016-08-15 |
2023-08-13 |
Not clear |