All Relations between 5-ht receptor 2a and 5-ht system

Publication Sentence Publish Date Extraction Date Species
b' Paola Giuliano, Giuliana La Rosa, Serena Capozzi, Emanuele Cassano, Simona Damiano, Francesco Habetswallner, Rosa Iodice, Maurizio Marra, Luigi Michele Pavone, Mario Quarantelli, Giuseppe Vitelli, Mariarosaria Santillo, Roberto Patern\\xc3\\xb. A Blood Test for the Diagnosis of Multiple Sclerosis. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38338973.' in this study, since there is evidence connecting the serotonin pathway to ms, we used an elisa (enzyme-linked immunosorbent assay) to detect serum ms-specific auto-antibodies (auto-ab) against the extracellular loop 1 (ecl-1) of the 5-hydroxytryptamine (5-ht) receptor subtype 2a (5-ht2a). 2024-02-10 2024-02-12 Not clear
Federico Seragnoli, Daniel Pires Martins, Gabriel Thoren. [Microdosing LSD: practices and risks]. Revue medicale suisse. vol 17. issue 742. 2021-06-11. PMID:34106534. lsd's main effect is on the serotonin system, in particular on 5-ht2a receptors, a receptor involved in neurobiological processes underlying learning. 2021-06-11 2023-08-13 human
P R Butovskaya, O E Lazebnij, D I Fekhretdionva, V A Vasil'ev, E A Prosikova, V V Lysenko, I G Udina, M L Butovskay. [ASSOCIATION BETWEEN FOUR SEROTONIC GENES POLYMORPHISM (5HTTL, 5HT1A, 5HT2A, AND MAOA) AND PERSONALITY TRAITS IN WRESTLERS AND CONTROL GROUP]. Molekuliarnaia genetika, mikrobiologiia i virusologiia. vol 33. issue 4. 2016-06-22. PMID:27192815. this study presents the data on the polymorphisms of the serotonin system genes (5-httl, 5-ht1a, 5-ht2a, and maoa) in male and female wrestlers and in the control group. 2016-06-22 2023-08-13 Not clear
Vladimir S Naumenko, Daria V Bazovkina, Alina A Semenova, Anton S Tsybko, Tatyana V Il'chibaeva, Elena M Kondaurova, Nina K Popov. Effect of glial cell line-derived neurotrophic factor on behavior and key members of the brain serotonin system in mouse strains genetically predisposed to behavioral disorders. Journal of neuroscience research. vol 91. issue 12. 2014-06-17. PMID:24105724. the results show 1) a gdnf-induced increase in the expression of key genes of the brain 5-ht system, tph2, 5-ht1a , and 5-ht2a receptors, and 2) significant genotype-dependent differences in the 5-ht system response to gdnf treatment. 2014-06-17 2023-08-12 mouse
Philippe Huot, Susan H Fo. The serotonergic system in motor and non-motor manifestations of Parkinson's disease. Experimental brain research. vol 230. issue 4. 2014-05-27. PMID:23811734. although the 5-ht system uses one transporter (sert) and 14 receptor sub-types, most of the studies in pd have focussed on sert and serotonergic type 1a and 2a receptors (5-ht1a and 5-ht2a). 2014-05-27 2023-08-12 Not clear
Nina K Popova, Vladimir S Naumenk. 5-HT1A receptor as a key player in the brain 5-HT system. Reviews in the neurosciences. vol 24. issue 2. 2013-08-21. PMID:23492554. specifically, it describes the (1) functional interactions between 5-ht1a, 5-ht2a, 5-ht3, and 5-ht7 receptors; (2) cross-talk between 5-ht1a receptor and genes encoding key members of the brain 5-ht system; (3) implication of the 5-ht1a receptor in natural hibernation and genetic predisposition to different kinds of defensive behavior; and (4) role of 5-ht1a autoreceptors and heteroreceptors in anxiety, depression, and suicide, and in the antidepressant effect of serotonin reuptake inhibitors. 2013-08-21 2023-08-12 Not clear
Li Li, Guozhen Qiu, Shengyuan Ding, Fu-Ming Zho. Serotonin hyperinnervation and upregulated 5-HT2A receptor expression and motor-stimulating function in nigrostriatal dopamine-deficient Pitx3 mutant mice. Brain research. vol 1491. 2013-05-31. PMID:23159831. the striatum receives serotonin (5-hydroxytryptamine, 5-ht) innervation and expresses 5-ht2a receptors (5-ht2ars) and other 5-ht receptors, raising the possibility that the striatal 5-ht system may undergo adaptive changes after chronic severe dopamine (da) loss and contribute to the function and dysfunction of the striatum. 2013-05-31 2023-08-12 mouse
V S Naumenko, A S Tsybko, D V Bazovkina, N K Popov. [Implication of 5-HT2A receptors in the genetic mechanisms of the brain 5-HT system autoregulation]. Molekuliarnaia biologiia. vol 46. issue 3. 2012-08-29. PMID:22888631. here, we investigated the role of 5-ht2a receptor in the autoregulation of the brain 5-ht system. 2012-08-29 2023-08-12 mouse
V S Naumenko, A S Tsybko, D V Bazovkina, N K Popov. [Implication of 5-HT2A receptors in the genetic mechanisms of the brain 5-HT system autoregulation]. Molekuliarnaia biologiia. vol 46. issue 3. 2012-08-29. PMID:22888631. [implication of 5-ht2a receptors in the genetic mechanisms of the brain 5-ht system autoregulation]. 2012-08-29 2023-08-12 mouse
V S Naumenko, A S Tsybko, D V Bazovkina, N K Popov. [Implication of 5-HT2A receptors in the genetic mechanisms of the brain 5-HT system autoregulation]. Molekuliarnaia biologiia. vol 46. issue 3. 2012-08-29. PMID:22888631. the results provide new evidence of receptor-gene cross-talk in the brain 5-ht system and the implication of 5-ht2a receptor in the autoregulation of the brain 5-ht system. 2012-08-29 2023-08-12 mouse
Tomomi Kitagawa, Yukihiro Yokoyama, Toshio Kokuryo, Toru Kawai, Katsutaka Watanabe, Kiyotaka Kawai, Masato Nagin. Estrogen promotes hepatic regeneration via activating serotonin signal. Shock (Augusta, Ga.). vol 31. issue 6. 2009-08-21. PMID:18948847. gene expression of serotonin receptor (5-ht2a) in the liver and tryptophan hydroxylase 1 in the small intestine were also up-regulated in the e group, indicating an activation of serotonin system in the e group. 2009-08-21 2023-08-12 rat
Masaki Kato, Raffaella Zanardi, David Rossini, Diana De Ronchi, Gaku Okugawa, Toshihiko Kinoshita, Cristina Colombo, Alessandro Serrett. 5-HT2A gene variants influence specific and different aspects of antidepressant response in Japanese and Italian mood disorder patients. Psychiatry research. vol 167. issue 1-2. 2009-06-10. PMID:19361869. the 5-ht2a receptor is a key modulator of the serotonin pathway. 2009-06-10 2023-08-12 Not clear
Xingqun Ni, David Chan, Kirsten Chan, Shelley McMain, James L Kenned. Serotonin genes and gene-gene interactions in borderline personality disorder in a matched case-control study. Progress in neuro-psychopharmacology & biological psychiatry. vol 33. issue 1. 2009-04-02. PMID:19032968. the multifactor dimensionality reduction analysis was used to examine gene-gene interactions in serotonin system, including three other genes (5-htt, 5-ht2a and maoa) that we previously reported. 2009-04-02 2023-08-12 Not clear
Nobuaki Egashira, Katsunori Iwasaki, Ayumi Ishibashi, Kazuhide Hayakawa, Ryoko Okuno, Moe Abe, Naoki Uchida, Kenichi Mishima, Kotaro Takasaki, Ryoji Nishimura, Ryozo Oishi, Michihiro Fujiwar. Repeated administration of Yokukansan inhibits DOI-induced head-twitch response and decreases expression of 5-hydroxytryptamine (5-HT)2A receptors in the prefrontal cortex. Progress in neuro-psychopharmacology & biological psychiatry. vol 32. issue 6. 2008-10-22. PMID:18558456. these findings suggest that the inhibition of doi-induced head-twitch response by yks may be mediated, in part, by altered expression of 5-ht2a receptors in the prefrontal cortex, which suggests the involvement of the 5-ht system in psychopharmacological effects of yks. 2008-10-22 2023-08-12 mouse
Wiesław Jerzy Cubała, Jerzy Landowsk. [Serotoninergic system and limbic-hypothalamic-pituitary-adrenal axis (LHPA axis) in depression]. Psychiatria polska. vol 40. issue 3. 2007-02-08. PMID:17037809. in depression, the 5-ht system exhibits impaired presynaptic activity of 5-ht neurones, an increased activity of central postsynaptic 5-ht2a receptors, decreased activity of postsynaptic 5-ht1a receptors and altered synaptic 5-ht uptake. 2007-02-08 2023-08-12 Not clear
Maribel Rios, Evelyn K Lambe, Rongjian Liu, Sarah Teillon, JinHong Liu, Schahram Akbarian, Suzanne Roffler-Tarlov, Rudolf Jaenisch, George K Aghajania. Severe deficits in 5-HT2A -mediated neurotransmission in BDNF conditional mutant mice. Journal of neurobiology. vol 66. issue 4. 2006-04-28. PMID:16408297. these findings suggest that postnatal levels of bdnf play a relatively limited role in maintaining presynaptic aspects of the serotonin system and a much greater role in maintaining postsynaptic 5-ht2a and possibly other receptors than previously suspected. 2006-04-28 2023-08-12 mouse
I S Chee, S W Lee, J L Kim, S K Wang, Y O Shin, S C Shin, Y H Lee, H M Hwang, M R Li. 5-HT2A receptor gene promoter polymorphism -1438A/G and bipolar disorder. Psychiatric genetics. vol 11. issue 3. 2002-05-02. PMID:11702051. genetic factors, such as the genes involved in the serotonin pathway, probably play an important role in the pathogenesis of bipolar disorder, and serotonin type 2a (5-ht2a) receptor gene promoter polymorphism -1438a/g has been reported. 2002-05-02 2023-08-12 human
A V Kulikov, R Jeanningr. The effects of hypothyroidism on 5-HT1A and 5-HT2A receptors and the serotonin transporter protein in the rat brain. Neuroscience and behavioral physiology. vol 31. issue 4. 2002-01-09. PMID:11508497. thus, losses of cortical 5-ht2a receptors appears to be the main consequence of hypothyroidism at the level of the serotonin system of the brain. 2002-01-09 2023-08-12 rat
O Spigset, C Wilhelmsson, T Mjörndal, S Eriksso. Serotonin 5-HT2A receptor binding in platelets from patients with Alzheimer's disease or vascular dementia. International psychogeriatrics. vol 12. issue 4. 2001-05-24. PMID:11263719. the present study was performed in order to investigate whether a peripheral serotonin system marker, the platelet 5-ht2a receptor, is affected in dementia. 2001-05-24 2023-08-12 Not clear
B Nacmias, V Ricca, A Tedde, B Mezzani, C M Rotella, S Sorb. 5-HT2A receptor gene polymorphisms in anorexia nervosa and bulimia nervosa. Neuroscience letters. vol 277. issue 2. 2000-02-08. PMID:10624828. to examine the distribution of different polymorphisms in genes of the 5-ht system in patients with anorexia nervosa (an) and bulimia nervosa (bn), we analyzed the distribution of a polymorphism (-1438g/a) and the presence of known mutations in 5-ht2a and 5-ht2c receptor genes in 168 italian female patients affected by an and bn. 2000-02-08 2023-08-12 Not clear