| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Manabu Takano, Tsuyoshi Okada, Katsutoshi Shioda, Chikara Yonekawa, Shiro Sud. Risperidone suppresses caffeine-induced hyperthermia and hyperactivity in rats. Neuroscience letters. 2024-09-02. PMID:39222834. |
risperidone and 5-ht2a receptor antagonist ketanserin attenuated caffeine-induced hyperthermia and hyperactivity. |
2024-09-02 |
2024-09-05 |
rat |
| Manabu Takano, Tsuyoshi Okada, Katsutoshi Shioda, Chikara Yonekawa, Shiro Sud. Risperidone suppresses caffeine-induced hyperthermia and hyperactivity in rats. Neuroscience letters. 2024-09-02. PMID:39222834. |
our results indicate that risperidone attenuates caffeine-induced hyperthermia and hyperactivity by blocking 5-ht2a receptor activity and may be potentially useful for treating caffeine intoxication. |
2024-09-02 |
2024-09-05 |
rat |
| Samantha Alvarez-Herrera, Mauricio Rosel Vales, Gilberto Pérez-Sánchez, Enrique Becerril-Villanueva, Yvonne Flores-Medina, José Luis Maldonado-García, Ricardo Saracco-Alvarez, Raúl Escamilla, Lenin Pavó. Risperidone Decreases Expression of Serotonin Receptor-2A (5-HT2A) and Serotonin Transporter (SERT) but Not Dopamine Receptors and Dopamine Transporter (DAT) in PBMCs from Patients with Schizophrenia. Pharmaceuticals (Basel, Switzerland). vol 17. issue 2. 2024-02-24. PMID:38399382. |
risperidone decreases expression of serotonin receptor-2a (5-ht2a) and serotonin transporter (sert) but not dopamine receptors and dopamine transporter (dat) in pbmcs from patients with schizophrenia. |
2024-02-24 |
2024-02-26 |
Not clear |
| Muhammad Ishrat Husain, Daniel M Blumberger, David J Castle, Nicole Ledwos, Elise Fellows, Brett D M Jones, Abigail Ortiz, Stefan Kloiber, Wei Wang, Joshua D Rosenblat, Benoit H Mulsan. Psilocybin for treatment-resistant depression without psychedelic effects: study protocol for a 4-week, double-blind, proof-of-concept randomised controlled trial. BJPsych open. vol 9. issue 4. 2023-07-25. PMID:37489299. |
these effects depend on serotonin 2a (5-ht2a) receptor activation, which can be blocked by 5-ht2a receptor antagonists like ketanserin or risperidone. |
2023-07-25 |
2023-08-14 |
Not clear |
| Tsuyoshi Okada, Katsutoshi Shioda, Akiko Makiguchi, Shiro Sud. Risperidone and 5-HT2A Receptor Antagonists Attenuate and Reverse Cocaine-Induced Hyperthermia in Rats. The international journal of neuropsychopharmacology. vol 23. issue 12. 2021-11-23. PMID:32821948. |
risperidone and 5-ht2a receptor antagonists attenuate and reverse cocaine-induced hyperthermia in rats. |
2021-11-23 |
2023-08-13 |
rat |
| Gurjit Kaur, Deepti Gupta, Bir Singh Chavan, Vikas Sinhmar, Rajendra Prasad, Adarsh Tripathi, P D Garg, Rajiv Gupta, Hitesh Khurana, Shiv Gautam, Mushtaq Ahmed Margoob, Jitender Anej. Identification of genetic correlates of response to Risperidone: Findings of a multicentric schizophrenia study from India. Asian journal of psychiatry. vol 29. 2018-06-22. PMID:28692863. |
so, we attempted to evaluate the association between dopamine d2 (drd2) receptor, serotonergic (5ht2a) receptor and cyp2d6 gene polymorphisms and response to treatment with risperidone in persons with schizophrenia from north india. |
2018-06-22 |
2023-08-13 |
Not clear |
| Gurjit Kaur, Deepti Gupta, Bir Singh Chavan, Vikas Sinhmar, Rajendra Prasad, Adarsh Tripathi, P D Garg, Rajiv Gupta, Hitesh Khurana, Shiv Gautam, Mushtaq Ahmed Margoob, Jitender Anej. Identification of genetic correlates of response to Risperidone: Findings of a multicentric schizophrenia study from India. Asian journal of psychiatry. vol 29. 2018-06-22. PMID:28692863. |
drd2, 5-ht2a and cyp2d6 along with socio-demographical and clinical variables were analyzed to ascertain the association in response to risperidone treatment. |
2018-06-22 |
2023-08-13 |
Not clear |
| Gurjit Kaur, Deepti Gupta, Bir Singh Chavan, Vikas Sinhmar, Rajendra Prasad, Adarsh Tripathi, P D Garg, Rajiv Gupta, Hitesh Khurana, Shiv Gautam, Mushtaq Ahmed Margoob, Jitender Anej. Identification of genetic correlates of response to Risperidone: Findings of a multicentric schizophrenia study from India. Asian journal of psychiatry. vol 29. 2018-06-22. PMID:28692863. |
presence of drd2 taq 1 d2d2 and 5-ht2a c516t ct genotypes in patients were more likely to be associated with non-response to risperidone. |
2018-06-22 |
2023-08-13 |
Not clear |
| Jason Younkin, Supriya A Gaitonde, Amr Ellaithy, Rakesh Vekariya, Lia Baki, José L Moreno, Sneha Shah, Peter Drossopoulos, Kelsey S Hideshima, Jose Miguel Eltit, Javier González-Maeso, Diomedes E Logothetis, Malgorzata Dukat, Richard A Glenno. Reformulating a Pharmacophore for 5-HT2A Serotonin Receptor Antagonists. ACS chemical neuroscience. vol 7. issue 9. 2017-10-27. PMID:27385190. |
because our preliminary data indicated that two aromatic (hydrophobic) moieties might not be required for such action, we deconstructed the serotonin-dopamine antipsychotic agent risperidone (1) into four smaller structural fragments that were thoroughly examined in 5-ht2a receptor binding and functional (i.e., two-electrode voltage clamp (tevc) and intracellular calcium release) assays. |
2017-10-27 |
2023-08-13 |
Not clear |
| Aung Aung Kywe Moe, Nyoman D Kurniawan, Suzanne Alexander, Xiaoying Cui, Thomas H J Burne, Darryl W Eyle. Risperidone induces long-lasting changes in the conditioned avoidance response and accumbal gene expression selectively in animals treated as adolescents. Neuropharmacology. vol 108. 2017-07-18. PMID:27130903. |
impaired 5ht2a receptor signaling may explain the increased car suppression observed in rats treated with risperidone as adolescents. |
2017-07-18 |
2023-08-13 |
rat |
| Luciana Romina Frick, Micaela Bernardez-Vidal, Christian Hocht, Bonifacio Silvano Zanutto, Maximiliano Rapanell. Dual role of serotonin in the acquisition and extinction of reward-driven learning: involvement of 5-HT1A, 5-HT2A and 5-HT3 receptors. Behavioural brain research. vol 277. 2015-09-08. PMID:24949809. |
long evans rats were trained in an operant conditioning task while receiving fluoxetine (serotonin reuptake inhibitor, 10mg/kg), tianeptine (serotonin reuptake enhancer, 10mg/kg), buspirone (5-ht1a partial agonist, 10mg/kg), risperidone (5-ht2a antagonist, 1mg/kg), ondansetron (5-ht3 antagonist, 2mg/kg) or vehicle. |
2015-09-08 |
2023-08-13 |
rat |
| Dionisio A Amodeo, Joshua H Jones, John A Sweeney, Michael E Ragozzin. Risperidone and the 5-HT2A receptor antagonist M100907 improve probabilistic reversal learning in BTBR T + tf/J mice. Autism research : official journal of the International Society for Autism Research. vol 7. issue 5. 2015-06-22. PMID:24894823. |
risperidone and the 5-ht2a receptor antagonist m100907 improve probabilistic reversal learning in btbr t + tf/j mice. |
2015-06-22 |
2023-08-13 |
mouse |
| Dionisio A Amodeo, Joshua H Jones, John A Sweeney, Michael E Ragozzin. Risperidone and the 5-HT2A receptor antagonist M100907 improve probabilistic reversal learning in BTBR T + tf/J mice. Autism research : official journal of the International Society for Autism Research. vol 7. issue 5. 2015-06-22. PMID:24894823. |
the present study investigated whether risperidone and/or m100907, a 5ht2a receptor antagonist, improved probabilistic reversal learning performance in the btbr t + tf/j (btbr) mouse model of autism. |
2015-06-22 |
2023-08-13 |
mouse |
| Dionisio A Amodeo, Joshua H Jones, John A Sweeney, Michael E Ragozzin. Risperidone and the 5-HT2A receptor antagonist M100907 improve probabilistic reversal learning in BTBR T + tf/J mice. Autism research : official journal of the International Society for Autism Research. vol 7. issue 5. 2015-06-22. PMID:24894823. |
because risperidone can lead to unwanted side effects, treatment with a specific 5ht2a receptor antagonist may improve cognitive flexibility in individuals with asd while also minimizing unwanted side effects. |
2015-06-22 |
2023-08-13 |
mouse |
| Maurizio S Riga, Guadalupe Soria, Raúl Tudela, Francesc Artigas, Pau Celad. The natural hallucinogen 5-MeO-DMT, component of Ayahuasca, disrupts cortical function in rats: reversal by antipsychotic drugs. The international journal of neuropsychopharmacology. vol 17. issue 8. 2015-04-14. PMID:24650558. |
the latter effect depended on 5-ht1a and 5-ht2a receptor activation and was reversed by haloperidol, clozapine, risperidone, and the mglu2/3 agonist ly379268. |
2015-04-14 |
2023-08-12 |
rat |
| Katarzyna Fijał, Piotr Popik, Agnieszka Nikiforu. Co-administration of 5-HT6 receptor antagonists with clozapine, risperidone, and a 5-HT2A receptor antagonist: effects on prepulse inhibition in rats. Psychopharmacology. vol 231. issue 1. 2014-08-18. PMID:23954911. |
co-administration of 5-ht6 receptor antagonists with clozapine, risperidone, and a 5-ht2a receptor antagonist: effects on prepulse inhibition in rats. |
2014-08-18 |
2023-08-12 |
rat |
| Maximiliano Rapanelli, Luciana Romina Frick, Micaela Bernardez-Vidal, Bonifacio Silvano Zanutt. Different MK-801 administration schedules induce mild to severe learning impairments in an operant conditioning task: role of buspirone and risperidone in ameliorating these cognitive deficits. Behavioural brain research. vol 257. 2014-06-25. PMID:24095879. |
next, we orally administered risperidone (serotonin receptor 2a and dopamine receptor 2 antagonist, 1mg/kg) or buspirone (serotonin receptor 1a partial agonist, 10mg/kg) to animals treated with the mk-801 schedule described above. |
2014-06-25 |
2023-08-12 |
rat |
| C Roger-Sánchez, M Rodríguez-Arias, J Miñarro, M A Aguila. Effects of risperidone on the acquisition and reinstatement of the conditioned place preference induced by MDMA. Brain research bulletin. vol 98. 2014-05-30. PMID:23892054. |
in the present study we have evaluated the capacity of the mixed serotonin (5-ht2a)/dopamine (da d2) antagonist risperidone to block acquisition and reinstatement of mdma induced-cpp. |
2014-05-30 |
2023-08-12 |
mouse |
| Katsuya Takeuchi, Katsumi Sanjo, Akio Saka. [Paliperidone, risperidone]. Nihon rinsho. Japanese journal of clinical medicine. vol 71. issue 4. 2013-09-25. PMID:23678595. |
risperidone, a serotonin-dopamine antagonist, is effective in preventing delusions and hallucinations by d2 receptor antagonism and treating negative symptoms by 5-ht2a receptor antagonism. |
2013-09-25 |
2023-08-12 |
Not clear |
| Sandip Shah, Dipti Josh. Tolerability and efficacy of paliperidone ER compared to olanzapine in the treatment of schizophrenia: A randomized, double-blind, multicentric trial. Industrial psychiatry journal. vol 20. issue 1. 2012-10-02. PMID:22969177. |
paliperidone is an active metabolite of risperidone and actss through a combination of central dopamine type 2 (d2) and serotonin type 2 (5ht2a) receptor antagonism. |
2012-10-02 |
2023-08-12 |
Not clear |