| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Gärde, G J Matheson, K Varnäs, P Svenningsson, E Hedman-Lagerlöf, J Lundberg, L Farde, M Tige. Altered serotonin 1B receptor binding after escitalopram for depression is correlated with treatment effect. The international journal of neuropsychopharmacology. 2024-05-02. PMID:38695786. |
the serotonin 1b (5-ht1b) receptor is functionally linked to 5-htt and 5-ht1b receptor binding and 5-ht1b receptor mrna is reduced in the raphe nuclei after ssri-administration in primates and rodents respectively. |
2024-05-02 |
2024-05-04 |
human |
| Jeanette Wihan, Janina Grosch, Liubov S Kalinichenko, Christian P Müller, Jürgen Winkler, Zacharias Koh. Layer-specific axonal degeneration of serotonergic fibers in the prefrontal cortex of aged A53T α-synuclein-expressing mice. Neurobiology of aging. vol 80. 2020-04-30. PMID:31077958. |
together with increased tryptophan hydroxylase 2 mrna levels in the raphe nuclei and an elevated serotonin receptor 1b expression in the pfc, these findings point to compensatory mechanisms within the serotonergic system to overcome the reduced neuritic input to the pfc in this transgenic animal model for pd. |
2020-04-30 |
2023-08-13 |
mouse |
| Marta Rodriguez-Arias, Francisco Navarrete, Manuel Daza-Losada, Daniela Navarro, María A Aguilar, Pere Berbel, José Miñarro, Jorge Manzanare. CB1 cannabinoid receptor-mediated aggressive behavior. Neuropharmacology. vol 75. 2014-08-19. PMID:23916480. |
gene expression analyses of monoaminooxidase-a (mao-a), catechol-o-methyl-transferase (comt), 5-hydroxytriptamine transporter (5-htt) and 5-ht1b serotonergic receptor (5ht1br) in the median and dorsal raphe nuclei (mnr and dr, respectively) and in the amygdala (amy) were performed by real time-pcr. |
2014-08-19 |
2023-08-12 |
mouse |
| N A Urtikova, A Ia Sapronova, M J Brisorgueil, D Verge, M V Ugriumo. [Development of serotonergic neurons of dorsal raphe nuclei in mice with knockout of monoamine oxidase A and 5-HT1A and 5-HT1B autoreceptor]. Ontogenez. vol 40. issue 4. 2009-10-02. PMID:19705758. |
[development of serotonergic neurons of dorsal raphe nuclei in mice with knockout of monoamine oxidase a and 5-ht1a and 5-ht1b autoreceptor]. |
2009-10-02 |
2023-08-12 |
mouse |
| Teresa E Foley, Benjamin N Greenwood, Heidi E W Day, Lauren G Koch, Steven L Britton, Monika Fleshne. Elevated central monoamine receptor mRNA in rats bred for high endurance capacity: implications for central fatigue. Behavioural brain research. vol 174. issue 1. 2006-11-28. PMID:16934883. |
hcr expressed higher levels of 5-ht1b autoreceptor mrna in the raphe nuclei relative to lcr, but similar levels of tph, 5-htt, and 5-ht1a mrna in these areas. |
2006-11-28 |
2023-08-12 |
rat |
| Michael S Clark, Ross A McDevitt, John F Neumaie. Quantitative mapping of tryptophan hydroxylase-2, 5-HT1A, 5-HT1B, and serotonin transporter expression across the anteroposterior axis of the rat dorsal and median raphe nuclei. The Journal of comparative neurology. vol 498. issue 5. 2006-10-18. PMID:16917826. |
quantitative mapping of tryptophan hydroxylase-2, 5-ht1a, 5-ht1b, and serotonin transporter expression across the anteroposterior axis of the rat dorsal and median raphe nuclei. |
2006-10-18 |
2023-08-12 |
rat |
| Benjamin N Greenwood, Teresa E Foley, Heidi E W Day, Daniel Burhans, Leah Brooks, Serge Campeau, Monika Fleshne. Wheel running alters serotonin (5-HT) transporter, 5-HT1A, 5-HT1B, and alpha 1b-adrenergic receptor mRNA in the rat raphe nuclei. Biological psychiatry. vol 57. issue 5. 2005-05-16. PMID:15737672. |
wheel running alters serotonin (5-ht) transporter, 5-ht1a, 5-ht1b, and alpha 1b-adrenergic receptor mrna in the rat raphe nuclei. |
2005-05-16 |
2023-08-12 |
rat |
| Youssef Sar. Serotonin1B receptors: from protein to physiological function and behavior. Neuroscience and biobehavioral reviews. vol 28. issue 6. 2005-01-11. PMID:15527863. |
the control of 5-ht release by 5-ht1b receptors was shown in projections arising from the raphe nuclei to fore- and midbrain regions. |
2005-01-11 |
2023-08-12 |
human |
| Eitan Gur, Michael E Newman, Yosefa Avraham, Eliyahu Dremencov, Elliot M Berr. The differential effects of food restriction on 5-HT1A and 5-HT1B receptor mediated control of serotonergic transmission in the hippocampus and hypothalamus of rats. Nutritional neuroscience. vol 6. issue 3. 2003-07-18. PMID:12793521. |
we recorded basal 5-ht release in the hypothalamus and hippocampus, and the sensitivity of the somatodendritic 5-ht1a autoreceptors in the raphe nuclei, and the nerve terminal 5-ht1b autoreceptors which together regulate the synthesis and release of 5-ht in these regions. |
2003-07-18 |
2023-08-12 |
rat |
| A Adell, P Celada, F Artiga. The role of 5-HT1B receptors in the regulation of serotonin cell firing and release in the rat brain. Journal of neurochemistry. vol 79. issue 1. 2001-10-25. PMID:11595769. |
these results suggest that 5-ht cell firing and release in midbrain raphe nuclei (particularly in the mnr) are under control of 5-ht1b receptors. |
2001-10-25 |
2023-08-12 |
rat |
| E Gur, B Lerer, E Dremencov, M E Newma. Chronic repetitive transcranial magnetic stimulation induces subsensitivity of presynaptic serotonergic autoreceptor activity in rat brain. Neuroreport. vol 11. issue 13. 2001-01-25. PMID:11006967. |
rats which had undergone chronic rtms showed reduced responses to both challenges, indicating subsensitivity of both the presynaptic 5-ht1a autoreceptors situated somatodendritically in the raphe nuclei and the 5-ht1b autoreceptors situated on nerve terminals. |
2001-01-25 |
2023-08-12 |
rat |
| C Roberts, D F Boyd, D N Middlemiss, C Routledg. Enhancement of 5-HT1B and 5-HT1D receptor antagonist effects on extracellular 5-HT levels in the guinea-pig brain following concurrent 5-HT1A or 5-HT re-uptake site blockade. Neuropharmacology. vol 38. issue 9. 1999-10-25. PMID:10471095. |
the aim of the study was to further investigate the autoreceptor roles of the 5-ht1a, 5-ht1b and 5-ht1d receptors in the median vs dorsal raphe nuclei. |
1999-10-25 |
2023-08-12 |
Not clear |
| F Héry, P Boulenguez, A Sémont, M Héry, D Becquet, M Faudon, P Deprez, M P Fach. Identification and role of serotonin 5-HT1A and 5-HT1B receptors in primary cultures of rat embryonic rostral raphe nucleus neurons. Journal of neurochemistry. vol 72. issue 5. 1999-05-06. PMID:10217255. |
we concluded that autoregulatory mechanisms involving 5-ht1a and 5-ht1b autoreceptors are functionally mature in cells from rostral raphe nuclei during the early period of development. |
1999-05-06 |
2023-08-12 |
rat |
| E Doucet, M Pohl, C M Fattaccini, J Adrien, S E Mestikawy, M Hamo. In situ hybridization evidence for the synthesis of 5-HT1B receptor in serotoninergic neurons of anterior raphe nuclei in the rat brain. Synapse (New York, N.Y.). vol 19. issue 1. 1995-05-09. PMID:7709340. |
this distribution was confirmed by in situ hybridization, which further revealed that the 5-ht1b mrna was present in dorsal root ganglia, the layer iv of the cerebral cortex, the purkinje cell layer of the cerebellum, the pyramidal neurons in the ca1 area of the hippocampus, and the dorsal and median raphe nuclei. |
1995-05-09 |
2023-08-12 |
rat |
| E Doucet, M Pohl, C M Fattaccini, J Adrien, S E Mestikawy, M Hamo. In situ hybridization evidence for the synthesis of 5-HT1B receptor in serotoninergic neurons of anterior raphe nuclei in the rat brain. Synapse (New York, N.Y.). vol 19. issue 1. 1995-05-09. PMID:7709340. |
in situ hybridization evidence for the synthesis of 5-ht1b receptor in serotoninergic neurons of anterior raphe nuclei in the rat brain. |
1995-05-09 |
2023-08-12 |
rat |
| E Doucet, M Pohl, C M Fattaccini, J Adrien, S E Mestikawy, M Hamo. In situ hybridization evidence for the synthesis of 5-HT1B receptor in serotoninergic neurons of anterior raphe nuclei in the rat brain. Synapse (New York, N.Y.). vol 19. issue 1. 1995-05-09. PMID:7709340. |
in lesioned rats, 5-ht1b mrna was present in the same areas and at the same levels as in control rats, except in the dorsal and median raphe nuclei, where a marked decrease (-75%) in its local concentration was observed. |
1995-05-09 |
2023-08-12 |
rat |
| M M Voigt, D J Laurie, P H Seeburg, A Bac. Molecular cloning and characterization of a rat brain cDNA encoding a 5-hydroxytryptamine1B receptor. The EMBO journal. vol 10. issue 13. 1992-01-31. PMID:1836757. |
in situ hybridization revealed expression of cognate mrna within cells of the dorsal and median raphe nuclei, consistent with previous reports that the 5-ht1b receptor acts as an autoreceptor on 5-ht terminals in this species. |
1992-01-31 |
2023-08-11 |
rat |
| H Sijbesma, J Schipper, E R de Kloet, J Mos, H van Aken, B Olivie. Postsynaptic 5-HT1 receptors and offensive aggression in rats: a combined behavioural and autoradiographic study with eltoprazine. Pharmacology, biochemistry, and behavior. vol 38. issue 2. 1991-07-31. PMID:1829232. |
quantitative autoradiographic studies 5 weeks after 5,7-dht treatment revealed a significant increase in radioligand binding to 5-ht1a, 5-ht1b and 5-ht1c sites in many brain regions studied, except for the raphe nuclei where [3h]8-oh-dpat binding to 5-ht1a sites was markedly reduced. |
1991-07-31 |
2023-08-11 |
rat |