| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yuki Moriya, Yoshiyuki Kasahara, Kana Ishihara, Frank Scott Hall, Yoko Hagino, Ren\\xc3\\xa9 Hen, Kazutaka Ikeda, George R Uhl, Ichiro Sor. Heterozygous and homozygous gene knockout of the 5-HT1B receptor have different effects on methamphetamine-induced behavioral sensitization. Behavioural pharmacology. 2023-09-05. PMID:37668157. |
to clarify the action of meth in 5-ht1b ko mice the effects of meth on extracellular levels of da (daec) and 5-ht (5-htec) in the caudate putamen (cpu) and the nucleus accumbens (nac) were examined. |
2023-09-05 |
2023-09-07 |
mouse |
| Dennis A Burke, Veronica A Alvare. Serotonin receptors contribute to dopamine depression of lateral inhibition in the nucleus accumbens. Cell reports. vol 39. issue 6. 2022-05-11. PMID:35545050. |
this study clarifies the mechanistic understanding of dopamine actions in the nac by showing pathway-specific modulation of lateral inhibition and involvement of d2 and 5-ht1b receptors in dopamine depression of d2-msn synapses. |
2022-05-11 |
2023-08-13 |
mouse |
| Jessica J Walsh, Pierre Llorach, Daniel F Cardozo Pinto, Wendy Wenderski, Daniel J Christoffel, Juliana S Salgado, Boris D Heifets, Gerald R Crabtree, Robert C Malenk. Systemic enhancement of serotonin signaling reverses social deficits in multiple mouse models for ASD. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 11. 2021-09-16. PMID:34239048. |
we recently demonstrated that enhanced serotonin (5-ht) activity in the nucleus accumbens (nac), via optogenetic activation of 5-htergic inputs or direct infusion of a specific 5-ht1b receptor agonist, reverses social deficits in a genetic mouse model for asd based on 16p11.2 copy number variation. |
2021-09-16 |
2023-08-13 |
mouse |
| Chiung-Chun Huang, Che-Ming Yeh, Mei-Ying Wu, Kuei-Sen Hs. A single in vivo cocaine administration impairs 5-HT(1B) receptor-induced long-term depression in the nucleus accumbens. Journal of neurochemistry. vol 125. issue 6. 2013-08-06. PMID:23452061. |
here, we demonstrate that brief application of 5-ht or 5-ht1b receptor agonist cp 93129 induced a long-term depression (ltd) of glutamatergic transmission in nac neurons. |
2013-08-06 |
2023-08-12 |
mouse |
| Chiung-Chun Huang, Che-Ming Yeh, Mei-Ying Wu, Kuei-Sen Hs. A single in vivo cocaine administration impairs 5-HT(1B) receptor-induced long-term depression in the nucleus accumbens. Journal of neurochemistry. vol 125. issue 6. 2013-08-06. PMID:23452061. |
our results reveal a novel 5-ht1b receptor-mediated ltd in the nac and suggest that cocaine exposure may result in elevated phosphorylation of presynaptic proteins involved in regulating glutamate release, which counteracts the presynaptic depressant effects of 5-ht1b receptors and thereby impairs the induction of ltd by 5-ht. |
2013-08-06 |
2023-08-12 |
mouse |
| Qing-Shan Yan, Shi-Zhong Zheng, Shu-E Ya. Involvement of 5-HT1B receptors within the ventral tegmental area in regulation of mesolimbic dopaminergic neuronal activity via GABA mechanisms: a study with dual-probe microdialysis. Brain research. vol 1021. issue 1. 2004-11-08. PMID:15328035. |
co-infusion of the 5-ht1b receptor antagonist sb 216641 (10 microm), but not the 5-ht1a receptor antagonist way 100635 (10 microm) or the 5-ht1d/1a receptor antagonist brl 15572 (10 microm), antagonized not only the effects of intra-tegmental cp 93129 (80 microm) on vta da and nac da but also on vta gaba. |
2004-11-08 |
2023-08-12 |
rat |