| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qing Yang, Ximiao Zhang, Liming Zhang, Chen Cheng, Jingjing Zha. Exploring the influence of the DRD2 gene on mathematical ability: perspectives of gene association and gene-environment interaction. BMC psychology. vol 12. issue 1. 2024-10-19. PMID:39425204. |
this study focused on the effect of drd2, a candidate gene for working memory, on mathematical ability. |
2024-10-19 |
2024-10-21 |
human |
| Bryn Farnsworth von Cederwald, Jarkko Johansson, Katrine Riklund, Nina Karalija, Carl-Johan Boraxbek. White matter lesion load determines exercise-induced dopaminergic plasticity and working memory gains in aging. Translational psychiatry. vol 13. issue 1. 2023-01-31. PMID:36720847. |
while the intervention altered striatal drd2 availability and wm performance in individuals with no or only mild lesions (p < 0.05), no such effects were found in individuals with moderate-to-severe lesion severity (p > 0.05). |
2023-01-31 |
2023-08-14 |
Not clear |
| Bryn Farnsworth von Cederwald, Jarkko Johansson, Katrine Riklund, Nina Karalija, Carl-Johan Boraxbek. White matter lesion load determines exercise-induced dopaminergic plasticity and working memory gains in aging. Translational psychiatry. vol 13. issue 1. 2023-01-31. PMID:36720847. |
the present work focused on the impact of individual differences in white-matter lesion burden upon dopamine d2-like receptor (drd2) availability and wm changes in response to a 6 months physical activity intervention. |
2023-01-31 |
2023-08-14 |
Not clear |
| Bryn Farnsworth von Cederwald, Jarkko Johansson, Katrine Riklund, Nina Karalija, Carl-Johan Boraxbek. White matter lesion load determines exercise-induced dopaminergic plasticity and working memory gains in aging. Translational psychiatry. vol 13. issue 1. 2023-01-31. PMID:36720847. |
future work should assess whether these findings extend beyond measures of drd2 availability and wm. |
2023-01-31 |
2023-08-14 |
Not clear |
| Enrico D'Ambrosio, Giulio Pergola, Antonio F Pardiñas, Tarik Dahoun, Mattia Veronese, Leonardo Sportelli, Paolo Taurisano, Kira Griffiths, Sameer Jauhar, Maria Rogdaki, Michael A P Bloomfield, Sean Froudist-Walsh, Ilaria Bonoldi, James T R Walters, Giuseppe Blasi, Alessandro Bertolino, Oliver D Howe. A polygenic score indexing a DRD2-related co-expression network is associated with striatal dopamine function. Scientific reports. vol 12. issue 1. 2022-07-23. PMID:35871219. |
recent studies have shown that a polygenic co-expression index (pci) predicting the brain-specific expression of a network of genes co-expressed with drd2 was associated with response to antipsychotics, brain function during working memory in patients with schizophrenia, and with the modulation of prefrontal cortex activity after pharmacological stimulation of d2 receptors. |
2022-07-23 |
2023-08-14 |
human |
| Shirley Y Hill, Sarah Lichenstein, Shuhui Wang, Howard Carter, Michael McDermot. Caudate Volume in Offspring at Ultra High Risk for Alcohol Dependence: COMT Val158Met, DRD2, Externalizing Disorders, and Working Memory. Advances in molecular imaging. vol 3. issue 4. 2020-10-01. PMID:25364629. |
caudate volume in offspring at ultra high risk for alcohol dependence: comt val158met, drd2, externalizing disorders, and working memory. |
2020-10-01 |
2023-08-13 |
Not clear |
| Xin Li, Lars Bäckman, Jonas Persso. The relationship of age and DRD2 polymorphisms to frontostriatal brain activity and working memory performance. Neurobiology of aging. vol 84. 2020-08-04. PMID:31629117. |
the relationship of age and drd2 polymorphisms to frontostriatal brain activity and working memory performance. |
2020-08-04 |
2023-08-13 |
human |
| Xin Li, Lars Bäckman, Jonas Persso. The relationship of age and DRD2 polymorphisms to frontostriatal brain activity and working memory performance. Neurobiology of aging. vol 84. 2020-08-04. PMID:31629117. |
using functional mri, we investigated the relationship of age and these 2 drd2 gene polymorphisms to wm function and examined possible age by gene interactions. |
2020-08-04 |
2023-08-13 |
human |
| Kristel Klaus, Kyla Penningto. Dopamine and Working Memory: Genetic Variation, Stress and Implications for Mental Health. Current topics in behavioral neurosciences. vol 41. 2020-01-06. PMID:31502081. |
this chapter aims to evaluate the impact of key daergic gene variants suggested to impact on both synaptic da levels (comt, dat1, dbh, maoa) and da receptor function (ankk1, drd2, drd4) in terms of their influence on visuospatial wm. |
2020-01-06 |
2023-08-13 |
Not clear |
| Kristel Klaus, Kevin Butler, Ffion Curtis, Chris Bridle, Kyla Penningto. The effect of ANKK1 Taq1A and DRD2 C957T polymorphisms on executive function: A systematic review and meta-analysis. Neuroscience and biobehavioral reviews. vol 100. 2019-06-26. PMID:30836122. |
a systematic review and meta-analysis was carried out on the evidence for the association of drd2 c957t and ankk1 taq1a polymorphisms in performance on tasks relating to the three core domains of executive function: working memory, response inhibition and cognitive flexibility in healthy adults. |
2019-06-26 |
2023-08-13 |
Not clear |
| F Nemmi, C Nymberg, F Darki, T Banaschewski, A L W Bokde, C Büchel, H Flor, V Frouin, H Garavan, P Gowland, A Heinz, J-L Martinot, F Nees, T Paus, M N Smolka, T W Robbins, G Schumann, T Klingber. Interaction between striatal volume and DAT1 polymorphism predicts working memory development during adolescence. Developmental cognitive neuroscience. vol 30. 2019-06-13. PMID:29567584. |
at age 14 subjects underwent a structural mri scan, and genotyping of five single nucleotide polymorphisms (snps) in or close to the dopamine genes drd2, dat-1 and comt, which have previously been associated with gains in wm after wm training. |
2019-06-13 |
2023-08-13 |
human |
| G Pergola, P Di Carlo, E D'Ambrosio, B Gelao, L Fazio, M Papalino, A Monda, G Scozia, B Pietrangelo, M Attrotto, J A Apud, Q Chen, V S Mattay, A Rampino, G Caforio, D R Weinberger, G Blasi, A Bertolin. DRD2 co-expression network and a related polygenic index predict imaging, behavioral and clinical phenotypes linked to schizophrenia. Translational psychiatry. vol 7. issue 1. 2017-11-16. PMID:28094815. |
we examined genetic variants related to the dopamine d2 receptor gene drd2 co-expression pathway and associated them with working memory (wm) behavior, the related brain activity and treatment response. |
2017-11-16 |
2023-08-13 |
Not clear |
| G Pergola, P Di Carlo, E D'Ambrosio, B Gelao, L Fazio, M Papalino, A Monda, G Scozia, B Pietrangelo, M Attrotto, J A Apud, Q Chen, V S Mattay, A Rampino, G Caforio, D R Weinberger, G Blasi, A Bertolin. DRD2 co-expression network and a related polygenic index predict imaging, behavioral and clinical phenotypes linked to schizophrenia. Translational psychiatry. vol 7. issue 1. 2017-11-16. PMID:28094815. |
greater predicted drd2 pathway prefrontal co-expression was associated with greater prefrontal activity and longer wm reaction times (all corrected p<0.05), thus indicating inefficient wm processing. |
2017-11-16 |
2023-08-13 |
Not clear |
| Lorenza S Colzato, Laura Steenbergen, Roberta Sellaro, Ann-Kathrin Stock, Larissa Arning, Christian Best. Effects of l-Tyrosine on working memory and inhibitory control are determined by DRD2 genotypes: A randomized controlled trial. Cortex; a journal devoted to the study of the nervous system and behavior. vol 82. 2017-10-02. PMID:27403851. |
given that tyr increases da level in the brain, we investigated, in a double-blind, randomized, placebo-controlled design, whether the c957t genotypes of a functional synonymous polymorphism in the human dopamine d2 receptor (drd2) gene (rs6277) contribute to individual differences in the reactivity to tyr administration and whether this factor predicts the magnitude of tyr-induced performance differences on inhibiting behavioral responses in a stop-signal task and working memory (wm) updating in a n-back task. |
2017-10-02 |
2023-08-13 |
human |
| Lorenza S Colzato, Laura Steenbergen, Roberta Sellaro, Ann-Kathrin Stock, Larissa Arning, Christian Best. Effects of l-Tyrosine on working memory and inhibitory control are determined by DRD2 genotypes: A randomized controlled trial. Cortex; a journal devoted to the study of the nervous system and behavior. vol 82. 2017-10-02. PMID:27403851. |
effects of l-tyrosine on working memory and inhibitory control are determined by drd2 genotypes: a randomized controlled trial. |
2017-10-02 |
2023-08-13 |
human |
| Martin Bellander, Lars Bäckman, Tian Liu, Brit-Maren M Schjeide, Lars Bertram, Florian Schmiedek, Ulman Lindenberger, Martin Lövdé. Lower baseline performance but greater plasticity of working memory for carriers of the val allele of the COMT Val¹⁵⁸Met polymorphism. Neuropsychology. vol 29. issue 2. 2016-03-23. PMID:24819065. |
given that the neurotransmitter dopamine is critical for cognition and associated with cognitive plasticity, we investigated the effects of 3 polymorphisms of dopamine-related genes (lmx1a, drd2, comt) on baseline performance and plasticity of working memory (wm), perceptual speed, and reasoning. |
2016-03-23 |
2023-08-13 |
Not clear |
| Giuseppe Blasi, Pierluigi Selvaggi, Leonardo Fazio, Linda Antonella Antonucci, Paolo Taurisano, Rita Masellis, Raffaella Romano, Marina Mancini, Fengyu Zhang, Grazia Caforio, Teresa Popolizio, Jose Apud, Daniel R Weinberger, Alessandro Bertolin. Variation in Dopamine D2 and Serotonin 5-HT2A Receptor Genes is Associated with Working Memory Processing and Response to Treatment with Antipsychotics. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 7. 2016-01-25. PMID:25563748. |
in particular, the drd2 rs1076560 t allele predicts a lower ratio of expression of d2 short/long isoforms, suboptimal working memory processing, and better response to antipsychotic treatment compared with the g allele. |
2016-01-25 |
2023-08-13 |
human |
| Giuseppe Blasi, Pierluigi Selvaggi, Leonardo Fazio, Linda Antonella Antonucci, Paolo Taurisano, Rita Masellis, Raffaella Romano, Marina Mancini, Fengyu Zhang, Grazia Caforio, Teresa Popolizio, Jose Apud, Daniel R Weinberger, Alessandro Bertolin. Variation in Dopamine D2 and Serotonin 5-HT2A Receptor Genes is Associated with Working Memory Processing and Response to Treatment with Antipsychotics. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 7. 2016-01-25. PMID:25563748. |
these results indicate that drd2 and htr2a genetic variants together modulate physiological prefrontal efficiency during working memory and also modulate the response to antipsychotics. |
2016-01-25 |
2023-08-13 |
human |
| Torkel Klingber. Childhood cognitive development as a skill. Trends in cognitive sciences. vol 18. issue 11. 2015-07-20. PMID:25042686. |
the striatum, dopamine receptor d2 (drd2) activity, and corticostriatal white-matter tracts, on the other hand, seem to be more important for plasticity and change of wm capacity during both training and development. |
2015-07-20 |
2023-08-13 |
Not clear |
| Joey W Trampush, Michelle M Jacobs, Yasmin L Hurd, Jeffrey H Newcorn, Jeffrey M Halperi. Moderator effects of working memory on the stability of ADHD symptoms by dopamine receptor gene polymorphisms during development. Developmental science. vol 17. issue 4. 2015-02-12. PMID:24410775. |
we tested the hypothesis that dopamine d1 and d2 receptor gene (drd1 and drd2, respectively) polymorphisms and the development of working memory skills can interact to influence symptom change over 10 years in children with attention-deficit/hyperactivity disorder (adhd). |
2015-02-12 |
2023-08-12 |
human |