| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alyssa R Kniffin, Lisa A Brian. Sex differences in glutamate transmission and plasticity in reward related regions. Frontiers in behavioral neuroscience. vol 18. 2024-10-03. PMID:39359325. |
in combination with measures of glutamatergic transmission, synaptic plasticity can be evaluated using protocols that induce long-term potentiation or long-term depression. |
2024-10-03 |
2024-10-05 |
Not clear |
| Dowlette-Mary Alam El Din, Leah Moenkemoeller, Alon Loeffler, Forough Habibollahi, Jack Schenkman, Amitav Mitra, Tjitse van der Molen, Lixuan Ding, Jason Laird, Maren Schenke, Erik C Johnson, Brett J Kagan, Thomas Hartung, Lena Smirnov. Human Neural Organoid Microphysiological Systems Show the Building Blocks Necessary for Basic Learning and Memory. bioRxiv : the preprint server for biology. 2024-09-30. PMID:39345518. |
neural organoids showed synapse formation, glutamatergic and gabaergic receptor expression, immediate early gene expression basally and evoked, functional connectivity, criticality, and synaptic plasticity in response to theta-burst stimulation. |
2024-09-30 |
2024-10-02 |
human |
| Rebecca Z Weber, Beatriz Achon Buil, Nora H Rentsch, Allison Bosworth, Mingzi Zhang, Kassandra Kisler, Christian Tackenberg, Berislav V Zlokovic, Ruslan Rus. A molecular brain atlas reveals cellular shifts during the repair phase of stroke. bioRxiv : the preprint server for biology. 2024-09-04. PMID:39229128. |
for instance, gabaergic and glutamatergic neurons exhibited upregulated genes in signaling pathways involved in axon guidance and synaptic plasticity, and downregulated pathways associated with aerobic metabolism. |
2024-09-04 |
2024-09-06 |
mouse |
| Dirk Trauner, Philipp Leipppe, Prashant Donthamsetti, Tongil Ko, Cherise Stanley, Ehud Isacof. Cell-Specific Optical Control of AMPA Glutamate Receptors with a Photoswitchable Tethered Antagonist. Angewandte Chemie (International ed. in English). 2024-08-27. PMID:39189798. |
ampa receptors (ampars) are the main drivers of excitatory glutamatergic transmission in the brain, central to synaptic plasticity, and are key drug targets. |
2024-08-27 |
2024-08-30 |
Not clear |
| Eduardo Duarte-Silva, Alice Chevrollier Oriá, Ingrid Prata Mendonça, Igor Henrique Rodrigues Paiva, Klyvia Leuthier Dos Santos, Amanda Juliana Sales, José Roberto Botelho de Souza, Michael Maes, Sven Guenther Meuth, Christina Alves Peixot. The Antidepressant- and Anxiolytic-Like Effects of the Phosphodiesterase Type-5 Inhibitor Tadalafil are Associated with the Modulation of the Gut-Brain Axis During CNS Autoimmunity. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 19. issue 1. 2024-08-19. PMID:39158758. |
here, we showed that depressive-like behavior in experimental autoimmune encephalomyelitis (eae) mice is due to neuroinflammation, reduced synaptic plasticity, dysfunction in glutamatergic neurotransmission, glucocorticoid receptor (gr) resistance, increased blood-brain barrier (bbb) permeability, and immune cell infiltration to the cns, as well as inflammation, increased intestinal permeability, and immune cell infiltration in the distal colon. |
2024-08-19 |
2024-08-21 |
mouse |
| Yuehan Zhao, Yuan Peng, Yao Pan, Yichen Lv, Hongyu Zhou, Jiahao Wu, Jianwei Gong, Xin Wan. The role of ventral hippocampal-medial prefrontal glutamatergic pathway on the non-affected side in post-stroke cognitive impairment. Brain research. 2024-08-17. PMID:39153591. |
besides, synaptic plasticity, theta nerve oscillatory and the activity of glutamatergic neurons related to the ventral hippocampal-medial prefrontal glutamatergic neural pathway in the non-affected hemisphere (contralateral hemisphere to the lesion site) were observed. |
2024-08-17 |
2024-08-20 |
mouse |
| Yuehan Zhao, Yuan Peng, Yao Pan, Yichen Lv, Hongyu Zhou, Jiahao Wu, Jianwei Gong, Xin Wan. The role of ventral hippocampal-medial prefrontal glutamatergic pathway on the non-affected side in post-stroke cognitive impairment. Brain research. 2024-08-17. PMID:39153591. |
synaptic plasticity, theta nerve oscillatory synchronization and the activity of glutamatergic neurons of the ventral hippocampal-medial prefrontal glutamatergic neural pathway in the non-affected hemisphere was down-regulated in the psci group compared to those of the sham group. |
2024-08-17 |
2024-08-20 |
mouse |
| Peng Feng, Yuanhuan Chen, Kexin Sun, Xing Wei, Yanqin Ding, Jing Shang, Zheng Gang Shi, Xiaomin Xu, Junxiong Guo, Yongyan Tia. Volatile oil from Acori graminei Rhizoma affected the synaptic plasticity of rats with tic disorders by modulating dopaminergic and glutamatergic systems. Journal of ethnopharmacology. 2024-08-15. PMID:39147000. |
volatile oil from acori graminei rhizoma affected the synaptic plasticity of rats with tic disorders by modulating dopaminergic and glutamatergic systems. |
2024-08-15 |
2024-08-18 |
rat |
| Nuria García-Magro, Alberto Mesa-Lombardo, Natali Barros-Zulaica, Ángel Nuñe. Impairment of synaptic plasticity in the primary somatosensory cortex in a model of diabetic mice. Frontiers in cellular neuroscience. vol 18. 2024-08-14. PMID:39139399. |
in conclusion, impaired synaptic plasticity in the s1 cortex may stem from reduced igf-i signaling, leading to decreased intracellular signal pathways and thus, glutamatergic receptor numbers in the cellular membrane. |
2024-08-14 |
2024-08-16 |
mouse |
| Shenyu Zhai, Shintaro Otsuka, Jian Xu, Vernon R J Clarke, Tatiana Tkatch, David Wokosin, Zhong Xie, Asami Tanimura, Hitesh K Agarwal, Graham C R Ellis-Davies, Anis Contractor, D James Surmeie. Ca Cell reports. vol 43. issue 8. 2024-07-26. PMID:39058595. |
ca long-term synaptic plasticity at glutamatergic synapses on striatal spiny projection neurons (spns) is central to learning goal-directed behaviors and habits. |
2024-07-26 |
2024-07-29 |
Not clear |
| Ana Belén Sanz-Martos, María Roca, Mariano Ruiz-Gayo, Nuria Del Olm. TRIBUTYRIN REVERSES THE DELETERIOUS EFFECT OF SATURATED FAT ON WORKING MEMORY AND SYNAPTIC PLASTICITY IN JUVENILE MICE: DIFFERENTIAL EFFECTS IN MALES AND FEMALES. European journal of pharmacology. 2024-06-09. PMID:38852700. |
hippocampal expression of genes involved in glutamatergic transmission as well as synaptic plasticity (long-term potentiation -ltp- and long-term depression -ltd-) were also analyzed. |
2024-06-09 |
2024-06-14 |
mouse |
| Parsa Gholipour, Zahra Ebrahimi, Reihaneh Mohammadkhani, Reza Ghahremani, Iraj Salehi, Abdolrahman Sarihi, Alireza Komaki, Seyed Asaad Karim. Effects of (S)-3,4-DCPG, an mGlu8 receptor agonist, on hippocampal long-term potentiation at perforant pathway-dentate gyrus synapses in prenatal valproic acid-induced rat model of autism. Scientific reports. vol 14. issue 1. 2024-06-07. PMID:38849397. |
while the etiology of asd is multifaceted, abnormalities in glutamatergic neurotransmission and synaptic plasticity have been implicated. |
2024-06-07 |
2024-06-10 |
rat |
| Parsa Gholipour, Zahra Ebrahimi, Reihaneh Mohammadkhani, Reza Ghahremani, Iraj Salehi, Abdolrahman Sarihi, Alireza Komaki, Seyed Asaad Karim. Effects of (S)-3,4-DCPG, an mGlu8 receptor agonist, on hippocampal long-term potentiation at perforant pathway-dentate gyrus synapses in prenatal valproic acid-induced rat model of autism. Scientific reports. vol 14. issue 1. 2024-06-07. PMID:38849397. |
in conclusion, our study advances our understanding of the complex relationship between glutamatergic neurotransmission, synaptic plasticity, and vpa-induced autism model. |
2024-06-07 |
2024-06-10 |
rat |
| Zahra Ebrahimi, Parsa Gholipour, Reihaneh Mohammadkhani, Reza Ghahremani, Abdolrahman Sarihi, Alireza Komaki, Iraj Salehi, Seyed Asaad Karim. Effect of intrahippocampal microinjection of VU0155041, a positive allosteric modulator of mGluR4, on long term potentiation in a valproic acid-induced autistic male rat model. IBRO neuroscience reports. vol 16. 2024-06-04. PMID:38832089. |
despite the involvement of glutamatergic dysregulation in autism, the specific contribution of mglu4 receptors to synaptic plasticity remains unclear. |
2024-06-04 |
2024-06-06 |
rat |
| Jonas Petersen, Mette Q Ludwig, Vaida Juozaityte, Pablo Ranea-Robles, Charlotte Svendsen, Eunsang Hwang, Amalie W Kristensen, Nicole Fadahunsi, Jens Lund, Alberte W Breum, Cecilie V Mathiesen, Luisa Sachs, Roger Moreno-Justicia, Rebecca Rohlfs, James C Ford, Jonathan D Douros, Brian Finan, Bryan Portillo, Kyle Grose, Jacob E Petersen, Mette Trauelsen, Annette Feuchtinger, Richard D DiMarchi, Thue W Schwartz, Atul S Deshmukh, Morten B Thomsen, Kristi A Kohlmeier, Kevin W Williams, Tune H Pers, Bente Frølund, Kristian Strømgaard, Anders B Klein, Christoffer Clemmense. GLP-1-directed NMDA receptor antagonism for obesity treatment. Nature. 2024-05-15. PMID:38750368. |
genome-wide association studies suggest that glutamatergic neurotransmission and nmda receptor-mediated synaptic plasticity are important for body weight homeostasis |
2024-05-15 |
2024-05-27 |
Not clear |
| Shenyu Zhai, Shintaro Otsuka, Jian Xu, Vernon R J Clarke, Tatiana Tkatch, David Wokosin, Zhong Xie, Asami Tanimura, Hitesh K Agarwal, Graham C R Ellis-Davies, Anis Contractor, D James Surmeie. Ca bioRxiv : the preprint server for biology. 2024-05-07. PMID:38712260. |
ca long-term synaptic plasticity at glutamatergic synapses on striatal spiny projection neurons (spns) is central to learning goal-directed behaviors and habits. |
2024-05-07 |
2024-05-27 |
Not clear |
| José M Godoy Muñoz, Lasse Neset, Sigurbjörn Markússon, Sarah Weber, Oda C Krokengen, Aleksi Sutinen, Eleni Christakou, Andrea J Lopez, Clive R Bramham, Petri Kursul. Structural characterization of two nanobodies targeting the ligand-binding pocket of human Arc. PloS one. vol 19. issue 4. 2024-04-29. PMID:38683783. |
the activity-regulated cytoskeleton-associated protein (arc) is a complex regulator of synaptic plasticity in glutamatergic neurons. |
2024-04-29 |
2024-05-03 |
human |
| Sohrab Anvari, Mohammad Javan, Javad Mirnajafi-Zadeh, Yaghoub Fathollah. Repeated Morphine Exposure Alters Temporoamonic-CA1 Synaptic Plasticity in Male Rat Hippocampus. Neuroscience. 2024-03-21. PMID:38513764. |
in this study, the electrophysiological and biochemical consequences of repeated exposure to morphine in male rats on glutamatergic synaptic transmission, synaptic plasticity, the expression of gaba receptors and glutamate receptors at the temporoammonic-ca1 synapse along the longitudinal axis of the hippocampus (dorsal, intermediate, ventral, dh, ih, vh, respectively) were investigated. |
2024-03-21 |
2024-03-24 |
rat |
| Sohrab Anvari, Mohammad Javan, Javad Mirnajafi-Zadeh, Yaghoub Fathollah. Repeated Morphine Exposure Alters Temporoamonic-CA1 Synaptic Plasticity in Male Rat Hippocampus. Neuroscience. 2024-03-21. PMID:38513764. |
a distinct change in the short- and long-term synaptic plasticity along the hippocampus long axis due to repeated morphine exposure, partially mediated by a change in the expression profile of glutamatergic receptor subunits. |
2024-03-21 |
2024-03-24 |
rat |
| Yize Qi, Yao Zhou, Jiyang Li, Fangyuan Zhu, Gengni Guo, Can Wang, Man Yu, Yijie Wang, Tengfei Ma, Shanwu Feng, Li Zho. 3'-Deoxyadenosin alleviates methamphetamine-induced aberrant synaptic plasticity and seeking behavior by inhibiting the NLRP3 inflammasome. Neural regeneration research. vol 19. issue 10. 2024-03-15. PMID:38488561. |
furthermore, we found that 3'-deoxyadenosin reduced the aberrant potentiation of glutamatergic transmission and restored the methamphetamine-induced impairment of synaptic plasticity. |
2024-03-15 |
2024-03-17 |
mouse |