| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yun-Gwon Yeo, Jeongrak Park, Yoonsub Kim, Jong-Cheol Rah, Chang-Hoon Shin, Seo-Jin Oh, Jin-Hyeok Jang, Yaebin Lee, Jong Hyuk Yoon, Yong-Seok O. Retinoic acid modulation of granule cell activity and spatial discrimination in the adult hippocampus. Frontiers in cellular neuroscience. vol 18. 2024-05-02. PMID:38694537. |
retinoic acid modulation of granule cell activity and spatial discrimination in the adult hippocampus. |
2024-05-02 |
2024-05-04 |
mouse |
| Sara Hernández-Recio, Ricardo Muñoz-Arnaiz, Víctor López-Madrona, Julia Makarova, Oscar Herrera. Uncorrelated bilateral cortical input becomes timed across hippocampal subfields for long waves whereas gamma waves are largely ipsilateral. Frontiers in cellular neuroscience. vol 17. 2023-08-14. PMID:37576568. |
spatial discrimination techniques applied to bilateral laminar field potentials (fp) across the ca1/dentate gyrus provided simultaneous left and right readouts in five fp generators that reflect activity in specific hippocampal afferents and associative pathways. |
2023-08-14 |
2023-08-16 |
rat |
| Wenchong Sun, Jian Wang, Dasheng Cai, Ling Pe. Neuroprotection of the Developing Brain by Dexmedetomidine Is Mediated by Attenuating Single Propofol-induced Hippocampal Apoptosis and Synaptic Plasticity Deficits. Experimental neurobiology. vol 29. issue 5. 2020-11-14. PMID:33154198. |
induction of hippocampal long-term potentiation (ltp) of p30 rats and long-lasting performance of spatial discrimination at p30 and p60 were evaluated. |
2020-11-14 |
2023-08-13 |
rat |
| Ji H So, Chao Huang, Minyan Ge, Guangyao Cai, Lanqiu Zhang, Yisheng Lu, Yangling M. Intense Exercise Promotes Adult Hippocampal Neurogenesis But Not Spatial Discrimination. Frontiers in cellular neuroscience. vol 11. 2020-09-30. PMID:28197080. |
intense exercise promotes adult hippocampal neurogenesis but not spatial discrimination. |
2020-09-30 |
2023-08-13 |
Not clear |
| Ji H So, Chao Huang, Minyan Ge, Guangyao Cai, Lanqiu Zhang, Yisheng Lu, Yangling M. Corrigendum: Intense Exercise Promotes Adult Hippocampal Neurogenesis But Not Spatial Discrimination. Frontiers in cellular neuroscience. vol 13. 2020-09-30. PMID:31354430. |
corrigendum: intense exercise promotes adult hippocampal neurogenesis but not spatial discrimination. |
2020-09-30 |
2023-08-13 |
Not clear |
| Chia-Hsuan Fu, Daniel Maxim Iascone, Iraklis Petrof, Anupam Hazra, Xiaohong Zhang, Mark S Pyfer, Umberto Tosi, Brian F Corbett, Jingli Cai, Jason Lee, Jin Park, Lorraine Iacovitti, Helen E Scharfman, Grigori Enikolopov, Jeannie Chi. Early Seizure Activity Accelerates Depletion of Hippocampal Neural Stem Cells and Impairs Spatial Discrimination in an Alzheimer's Disease Model. Cell reports. vol 27. issue 13. 2020-07-30. PMID:31242408. |
early seizure activity accelerates depletion of hippocampal neural stem cells and impairs spatial discrimination in an alzheimer's disease model. |
2020-07-30 |
2023-08-13 |
mouse |
| Chen Li, Chunting Hu, Ruili Wang, Hui Wang, Qiaoya Ma, Songsheng Chen, Ya H. Protective effect of sakuranetin in brain cells of dementia model rats. Cellular and molecular biology (Noisy-le-Grand, France). vol 65. issue 5. 2019-12-17. PMID:31304907. |
in this study, the effect of sak on spatial discrimination in a rat model of cognitive dysfunction exposed to d-galactose was investigated with respect to its effect on malondialdehyde (mda), superoxide dismutase (sod) and glutathione peroxidase (gpx) levels, and on the expressions of interleukin-6 (il-6), tumor necrosis factor-α (tnf-α) and nuclear factor-κb inhibitory factor-α (iκbα) in hippocampus of rats. |
2019-12-17 |
2023-08-13 |
rat |
| Amanda C Marshall, Nicholas R Cooper, Nicolas Geeraer. The impact of experienced stress on aged spatial discrimination: Cortical overreliance as a result of hippocampal impairment. Hippocampus. vol 26. issue 3. 2016-11-14. PMID:26332910. |
the impact of experienced stress on aged spatial discrimination: cortical overreliance as a result of hippocampal impairment. |
2016-11-14 |
2023-08-13 |
human |
| Yu-Wen Chen, Dennis W Hwan. Multi-chromatic magnetic resonance imaging using frequency lock-in suppression. NMR in biomedicine. vol 28. issue 10. 2016-06-21. PMID:26282163. |
the contrast achieved in in vivo mouse brain imaging using the lock-in suppressed technique indicated a better spatial discrimination when compared with that achieved using conventional imaging methods, especially in the hippocampus region. |
2016-06-21 |
2023-08-13 |
mouse |
| E J Connors, A N Shaik, M M Migliore, A C Kentne. Environmental enrichment mitigates the sex-specific effects of gestational inflammation on social engagement and the hypothalamic pituitary adrenal axis-feedback system. Brain, behavior, and immunity. vol 42. 2015-12-14. PMID:25011058. |
ee protected against both the social and hypothalamic pituitary adrenal axis consequences of mia in juvenile male rats, but surprisingly not against the spatial discrimination deficits or accompanying decrease in glutamate levels within the hippocampus (as measured via lcms-ms). |
2015-12-14 |
2023-08-13 |
rat |
| P K Multani, R Hodge, M A Estévez, T Abel, H Kung, M Alter, B Brookshire, I Lucki, A H Nall, K Talbot, G A Doyle, F W Lohof. VMAT1 deletion causes neuronal loss in the hippocampus and neurocognitive deficits in spatial discrimination. Neuroscience. vol 232. 2015-07-14. PMID:23201251. |
vmat1 deletion causes neuronal loss in the hippocampus and neurocognitive deficits in spatial discrimination. |
2015-07-14 |
2023-08-12 |
mouse |
| N Benito, A Fernández-Ruiz, V A Makarov, J Makarova, A Korovaichuk, O Herrera. Spatial modules of coherent activity in pathway-specific LFPs in the hippocampus reflect topology and different modes of presynaptic synchronization. Cerebral cortex (New York, N.Y. : 1991). vol 24. issue 7. 2015-01-23. PMID:23395845. |
we have taken advantage of anatomical regularity of the rat hippocampus and combined multiple linear recordings and spatial discrimination techniques to separate pathway-specific lfps with enough spatial resolution to discriminate postsynaptic regions of varying activation, and to investigate their presynaptic origin, chemical nature, and spatial extension. |
2015-01-23 |
2023-08-12 |
rat |
| Yosuke Niibori, Tzong-Shiue Yu, Jonathan R Epp, Katherine G Akers, Sheena A Josselyn, Paul W Franklan. Suppression of adult neurogenesis impairs population coding of similar contexts in hippocampal CA3 region. Nature communications. vol 3. 2013-06-11. PMID:23212382. |
these data provide a neural basis for impaired spatial discrimination following ablation of adult neurogenesis, and support the proposal that adult neurogenesis regulates the efficiency of a pattern separation process in the hippocampus. |
2013-06-11 |
2023-08-12 |
Not clear |
| Jangjin Kim, Inah Le. Hippocampus is necessary for spatial discrimination using distal cue-configuration. Hippocampus. vol 21. issue 6. 2012-02-10. PMID:20623761. |
hippocampus is necessary for spatial discrimination using distal cue-configuration. |
2012-02-10 |
2023-08-12 |
rat |
| Michelle C Potter, Greg I Elmer, Richard Bergeron, Edson X Albuquerque, Paolo Guidetti, Hui-Qiu Wu, Robert Schwarc. Reduction of endogenous kynurenic acid formation enhances extracellular glutamate, hippocampal plasticity, and cognitive behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 8. 2010-09-17. PMID:20336058. |
at 21 days of age, kat ii knock-out mice had reduced hippocampal kyna levels (-71%) and showed significantly increased performance in three cognitive paradigms that rely in part on the integrity of hippocampal function, namely object exploration and recognition, passive avoidance, and spatial discrimination. |
2010-09-17 |
2023-08-12 |
mouse |
| Kim S Graham, Morgan D Barense, Andy C H Le. Going beyond LTM in the MTL: a synthesis of neuropsychological and neuroimaging findings on the role of the medial temporal lobe in memory and perception. Neuropsychologia. vol 48. issue 4. 2010-06-09. PMID:20074580. |
studies in rats and non-human primates suggest that medial temporal lobe (mtl) structures play a role in perceptual processing, with the hippocampus necessary for spatial discrimination, and the perirhinal cortex for object discrimination. |
2010-06-09 |
2023-08-12 |
human |
| Deborah J Watson, Mark E Stanto. Intrahippocampal administration of an NMDA-receptor antagonist impairs spatial discrimination reversal learning in weanling rats. Neurobiology of learning and memory. vol 92. issue 1. 2009-08-17. PMID:19248837. |
this study tested the hypothesis that hippocampal nmda receptors are engaged in weanling-age rats during spatial discrimination reversal training in a t-maze. |
2009-08-17 |
2023-08-12 |
rat |
| C D Clelland, M Choi, C Romberg, G D Clemenson, A Fragniere, P Tyers, S Jessberger, L M Saksida, R A Barker, F H Gage, T J Busse. A functional role for adult hippocampal neurogenesis in spatial pattern separation. Science (New York, N.Y.). vol 325. issue 5937. 2009-07-22. PMID:19590004. |
using adult mice in which hippocampal neurogenesis was ablated, we found specific impairments in spatial discrimination with two behavioral assays: (i) a spatial navigation radial arm maze task and (ii) a spatial, but non-navigable, task in the mouse touch screen. |
2009-07-22 |
2023-08-12 |
mouse |
| Thomas C Foster, Ashok Kuma. Susceptibility to induction of long-term depression is associated with impaired memory in aged Fischer 344 rats. Neurobiology of learning and memory. vol 87. issue 4. 2007-07-16. PMID:17276704. |
memory performance was measured on two tasks that are sensitive to hippocampal function; inhibitory avoidance and spatial discrimination on the morris water maze. |
2007-07-16 |
2023-08-12 |
rat |
| Wanda I Colón-Cesario, Michelle M Martínez-Montemayor, Sohaira Morales, Jahaira Félix, Juan Cruz, Monique Adorno, Lixmar Pereira, Nydia Colón, Carmen S Maldonado-Vlaar, Sandra Peña de Orti. Knockdown of Nurr1 in the rat hippocampus: implications to spatial discrimination learning and memory. Learning & memory (Cold Spring Harbor, N.Y.). vol 13. issue 6. 2007-01-25. PMID:17142303. |
knockdown of nurr1 in the rat hippocampus: implications to spatial discrimination learning and memory. |
2007-01-25 |
2023-08-12 |
rat |