All Relations between reward and prefrontal cortex

Publication Sentence Publish Date Extraction Date Species
Christiane Meyer, Konrad Schoettner, Shimon Ami. Effects of chronodisruption and alcohol consumption on gene expression in reward-related brain areas in female rats. Frontiers in molecular neuroscience. vol 17. 2024-12-03. PMID:39624490. to address this gap, adult female rats housed under an 11 h/11 h light-dark cycle (ld22) or standard light conditions (ld24, 12 h/12 h light-dark) were given access to an intermittent alcohol drinking protocol (ia20%) to assess the impact on gene expression in brain areas implicated in alcohol consumption and reward: the prefrontal cortex (pfc), nucleus accumbens (nac), and dorsal striatum (ds). 2024-12-03 2024-12-06 human
Sarah L Brassard, Hanson Liu, Jadyn Dosanjh, James MacKillop, Iris Balodi. Neurobiological foundations and clinical relevance of effort-based decision-making. Brain imaging and behavior. vol 18. issue 5. 2024-11-21. PMID:38819540. across 39 examined studies, the review highlights the ventromedial prefrontal cortex in forming reward-based predictions, the ventral striatum encoding expected subjective values driven by reward size, the dorsal anterior cingulate cortex for monitoring choices to maximize rewards, and specific motor areas preparing for effort expenditure. 2024-11-21 2024-11-23 Not clear
Jing Jiang, Stefania Ferraro, Youjin Zhao, Baolin Wu, Jinping Lin, Taolin Chen, Jin Gao, Lei L. Common and divergent neuroimaging features in major depression, posttraumatic stress disorder, and their comorbidity. Psychoradiology. vol 4. 2024-11-18. PMID:39554694. these functional magnetic resonance imaging (mri) studies highlight the (i) shared hypoactivation in the prefrontal cortex during cognitive and emotional processing in mdd and ptsd; (ii) higher activation in fear processing regions including amygdala, hippocampus, and insula in ptsd compared to mdd; and (iii) distinct functional deficits in brain regions involved in fear and reward processing in patients with ptsd + mdd relative to those with ptsd alone. 2024-11-18 2024-11-22 Not clear
Elizabeth Summerell, William Xiao, Chloe Huang, Jaden Terranova, Gadi Gilam, Paolo Riva, Thomas F Denso. The Effects of Transcranial Direct Current Stimulation over the Ventromedial Prefrontal Cortex on Reactive Aggression in Intoxicated and Sober Individuals. Biological psychology. 2024-11-06. PMID:39505295. the ventromedial prefrontal cortex (vmpfc) plays a critical role in representing the reward value of future actions. 2024-11-06 2024-11-09 human
Andrzej Sokołowski, Jesse A Brown, Ashlin R K Roy, Noah Cryns, Aaron Scheffler, Emily G Hardy, Samir Datta, William W Seeley, Virginia E Sturm, Bruce L Miller, Howard J Rosen, David C Perr. Structural and functional correlates of olfactory reward processing in behavioral variant frontotemporal dementia. Cortex; a journal devoted to the study of the nervous system and behavior. vol 181. 2024-11-02. PMID:39488010. regression analysis of resting-state brain functional connectivity indicated that more positive valence ratings of olfactory stimuli were predicted by ventral pallidum connectivity to other reward circuit regions, particularly functional connectivity between ventral pallidum and bilateral anterior cingulate cortex/ventromedial prefrontal cortex. 2024-11-02 2024-11-05 Not clear
Alyssa J Parker, Johanna C Walker, Yukari Takarae, Lea R Dougherty, Jillian Lee Wiggin. Neural mechanisms of reward processing in preadolescent irritability: Insights from the ABCD study. Journal of affective disorders. 2024-11-02. PMID:39488236. preadolescents with higher compared to lower levels of irritability demonstrated blunted prefrontal cortex activation in the anticipation period and exaggerated striatum-prefrontal connectivity differences among reward conditions during the feedback period. 2024-11-02 2024-11-05 human
Katelyn L Reeb, Sonita Wiah, Bhumiben P Patel, Stacia I Lewandowski, Ole V Mortensen, Joseph M Salvino, Scott M Rawls, Andréia C K Fontan. Positive allosteric modulation of glutamate transporter reduces cocaine-induced locomotion and expression of cocaine conditioned place preference in rats. European journal of pharmacology. 2024-09-30. PMID:39349114. the glutamatergic system, located throughout the brain including the prefrontal cortex and nucleus accumbens, plays a critical role in reward and reinforcement processing, and mediates the psychotropic effects of addictive drugs such as cocaine. 2024-09-30 2024-10-03 rat
Mingxin Ding, Porter L Tomsick, Ryan A Young, Shantanu P Jadha. Ventral tegmental area dopamine neural activity switches simultaneously with rule representations in the prefrontal cortex and hippocampus. bioRxiv : the preprint server for biology. 2024-09-24. PMID:39314328. neural activity in both the hippocampus (hpc) and prefrontal cortex (pfc) is known to represent spatial context and is sensitive to reward and rule alterations. 2024-09-24 2024-09-26 rat
Mingxin Ding, Porter L Tomsick, Ryan A Young, Shantanu P Jadha. Ventral tegmental area dopamine neural activity switches simultaneously with rule representations in the prefrontal cortex and hippocampus. bioRxiv : the preprint server for biology. 2024-09-24. PMID:39314328. ca1 and pfc ensembles showed rule-specific activity both during maze running and at reward locations, with pfc rule coding more consistent across animals compared to ca1. 2024-09-24 2024-09-26 rat
Katarzyna Skok, Napoleon Waszkiewic. Biomarkers of Internet Gaming Disorder-A Narrative Review. Journal of clinical medicine. vol 13. issue 17. 2024-09-14. PMID:39274323. in general, the connection of pfc with reward under cortex nuclei seems to be dysregulated. 2024-09-14 2024-09-16 Not clear
Tao Wang, Ruiyang Li, Dongyan Chen, Mei Xie, Zhiqiang Li, Huan Mao, Yuting Ling, Xiaoyun Liang, Guojun Xu, Jianjun Zhan. Modulation of High-Frequency rTMS on Reward Circuitry in Individuals with Nicotine Dependence: A Preliminary fMRI Study. Neural plasticity. vol 2024. 2024-09-05. PMID:39234068. this study aimed to investigate the effect of high-frequency rtms with the left dorsolateral prefrontal cortex (l-dlpfc) as a target region on smoking addiction in nicotine-dependent individuals by detecting the change of spontaneous brain activity in the reward circuitry. 2024-09-05 2024-09-08 human
Marco Nigro, Lucas Silva Tortorelli, Hongdian Yan. Distinct roles of prefrontal cortex neurons in set shifting. bioRxiv : the preprint server for biology. 2024-09-04. PMID:39229035. we recorded spiking activity from single pfc neurons in mice performing the attentional set-shifting task, where mice learned to associate different contextually relevant sensory stimuli to reward. 2024-09-04 2024-09-06 mouse
Wendy Sun, Anne Billot, Jingnan Du, Xiangyu Wei, Rachel A Lemley, Mohammad Daneshzand, Aapo Nummenmaa, Randy L Buckner, Mark C Eldaie. Precision Network Modeling of TMS Across Individuals Suggests Therapeutic Targets and Potential for Improvement. medRxiv : the preprint server for health sciences. 2024-08-26. PMID:39185539. we also modeled the impact of targeting the dorsolateral prefrontal cortex (dlpfc) zone anticorrelated with the sgacc and found that the individual-specific anticorrelated region variably targets a network coupled to reward circuitry. 2024-08-26 2024-08-28 Not clear
Huizi Tian, Zhifang Wang, Yao Meng, Lu Geng, Hao Lian, Zhifei Shi, Zhidong Zhuang, Wenpeng Cai, Mengyang H. Neural mechanisms underlying cognitive impairment in depression and cognitive benefits of exercise intervention. Behavioural brain research. 2024-08-25. PMID:39182624. depression is associated with certain neural impairments of reward processing, especially orbitofrontal cortex, prefrontal cortex, nucleus accumbens and other striatal regions. 2024-08-25 2024-08-28 Not clear
M F Koloski, S Hulyalkar, S A Barnes, J Mishra, D S Ramanatha. Cortico-striatal beta oscillations as a reward-related signal. Cognitive, affective & behavioral neuroscience. 2024-08-15. PMID:39147929. electrodes in orbitofrontal/medial prefrontal cortex, anterior insula, ventral striatum, and amygdala individually increased power and were functionally connected at beta frequencies during reward outcome. 2024-08-15 2024-08-18 rat
Ai Takehana, Daiki Tanaka, Mariko Arai, Yoshiki Hattori, Takaaki Yoshimoto, Teppei Matsui, Norihiro Sadato, Junichi Chikazoe, Koji Jimur. Healthy dietary choices involve prefrontal mechanisms associated with long-term reward maximization but not working memory. Cerebral cortex (New York, N.Y. : 1991). vol 34. issue 7. 2024-07-27. PMID:39066505. our results suggest that the prefrontal cortex plays a critical role in healthy food choice, which requires self-control, but not working memory, for maximization of reward attainments in a remote future. 2024-07-27 2024-07-29 human
Colin W Hoy, Coralie de Hemptinne, Sarah S Wang, Catherine J Harmer, Matthew A J Apps, Masud Husain, Philip A Starr, Simon Littl. Beta and theta oscillations track effort and previous reward in the human basal ganglia and prefrontal cortex during decision making. Proceedings of the National Academy of Sciences of the United States of America. vol 121. issue 31. 2024-07-25. PMID:39047043. beta and theta oscillations track effort and previous reward in the human basal ganglia and prefrontal cortex during decision making. 2024-07-25 2024-07-28 human
Colin W Hoy, Coralie de Hemptinne, Sarah S Wang, Catherine J Harmer, Matthew A J Apps, Masud Husain, Philip A Starr, Simon Littl. Beta and theta oscillations track effort and previous reward in the human basal ganglia and prefrontal cortex during decision making. Proceedings of the National Academy of Sciences of the United States of America. vol 121. issue 31. 2024-07-25. PMID:39047043. here, we report an exploratory investigation into this with chronic intracranial recordings from the prefrontal cortex (pfc) and basal ganglia (bg; subthalamic nuclei and globus pallidus) in people with parkinson's disease performing a decision-making task with offers that varied in levels of reward and physical effort required. 2024-07-25 2024-07-28 human
Colin W Hoy, Coralie de Hemptinne, Sarah S Wang, Catherine J Harmer, Matthew A J Apps, Masud Husain, Philip A Starr, Simon Littl. Beta and theta oscillations track effort and previous reward in the human basal ganglia and prefrontal cortex during decision making. Proceedings of the National Academy of Sciences of the United States of America. vol 121. issue 31. 2024-07-25. PMID:39047043. this revealed dissociable neural signatures of reward and effort, with bg beta (12 to 20 hz) oscillations tracking effort on a single-trial basis and pfc theta (4 to 7 hz) signaling previous trial reward, with no effects of net subjective value. 2024-07-25 2024-07-28 human
Colin W Hoy, Coralie de Hemptinne, Sarah S Wang, Catherine J Harmer, Matthew A J Apps, Masud Husain, Philip A Starr, Simon Littl. Beta and theta oscillations track effort and previous reward in the human basal ganglia and prefrontal cortex during decision making. Proceedings of the National Academy of Sciences of the United States of America. vol 121. issue 31. 2024-07-25. PMID:39047043. this work uncovers oscillatory mechanisms that guide fundamental decisions to exert effort for reward across bg and pfc, supports a causal role of pfc for such choices, and seeds hypotheses for future studies. 2024-07-25 2024-07-28 human