| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Samuel J Gershman, Armin La. Policy complexity suppresses dopamine responses. bioRxiv : the preprint server for biology. 2024-09-30. PMID:39345642. |
in support of this hypothesis, we find that policy complexity suppresses midbrain dopamine responses to reward outcomes, thereby reducing behavioral sensitivity to these outcomes. |
2024-09-30 |
2024-10-02 |
Not clear |
| Alain Rios, Kyohei Fujita, Yoshikazu Isomura, Nobuya Sat. Adaptive circuits for action and value information in rodent operant learning. Neuroscience research. 2024-09-28. PMID:39341460. |
we include insights from recent studies, which reveals the intricate roles of midbrain dopamine neurons in integrating action initiation and reward feedback, thereby enhancing movement-related activities in the dorsal striatum. |
2024-09-28 |
2024-10-01 |
Not clear |
| Mingxin Ding, Porter L Tomsick, Ryan A Young, Shantanu P Jadha. Ventral tegmental area dopamine neural activity switches simultaneously with rule representations in the prefrontal cortex and hippocampus. bioRxiv : the preprint server for biology. 2024-09-24. PMID:39314328. |
midbrain dopamine (da) activity is key in reward seeking behavior and learning. |
2024-09-24 |
2024-09-26 |
rat |
| Daniel F Hill, Robert W Hickman, Alaa Al-Mohammad, Arkadiusz Stasiak, Wolfram Schult. Dopamine neurons encode trial-by-trial subjective reward value in an auction-like task. Nature communications. vol 15. issue 1. 2024-09-17. PMID:39289338. |
in these highly experienced animals, responses of midbrain dopamine neurons followed the trial-by-trial variations of bids despite constant, explicitly predicted reward amounts. |
2024-09-17 |
2024-09-20 |
human |
| James D Howard, Donnisa Edmonds, Geoffrey Schoenbaum, Thorsten Kahn. Distributed midbrain responses signal the content of positive identity prediction errors. Current biology : CB. 2024-08-28. PMID:39197457. |
recent work across species has shown that midbrain dopamine neurons signal not only errors in the prediction of reward value but also in the prediction of value-neutral sensory features. |
2024-08-28 |
2024-09-01 |
human |
| Xiajie Feng, Ziyuan Ye, Kailai Xie, Shuqing Zhu, Xin Wu, Zhonghua Sun, Xiaohua Feng, Yingfen Mo, Jingwen Liang, Gang Shu, Songbo Wang, Canjun Zhu, Qingyan Jiang, Lina Wan. Effects of heat stress on the feeding preference of yellow-feathered broilers and its possible mechanism. Journal of thermal biology. vol 124. 2024-08-24. PMID:39180919. |
the insulin signaling pathway may participate in the regulation of heat stress on the male broiler reward system, while stress hormone-related receptors in the midbrain may play an important role in the effect of heat stress on the reward system of female broilers. |
2024-08-24 |
2024-08-28 |
Not clear |
| Jingjing Yang, Hongjuan Wang, Huan Chen, Hongwei Hou, Qingyuan H. The association of genetic polymorphisms within the dopaminergic system with nicotine dependence: A narrative review. Heliyon. vol 10. issue 12. 2024-07-18. PMID:39021905. |
nicotine acts on the limbic dopamine reward loop in the midbrain by binding to nicotinic acetylcholine receptors, promoting the release of dopamine, and resulting in a rewarding effect or satisfaction. |
2024-07-18 |
2024-07-20 |
Not clear |
| A A Conti, S Tolomeo, A Baldacchino, J D Steel. Blunted midbrain reward activation during smoking withdrawal: a preliminary study. Frontiers in pharmacology. vol 15. 2024-07-17. PMID:39015373. |
blunted midbrain reward activation during smoking withdrawal: a preliminary study. |
2024-07-17 |
2024-07-19 |
Not clear |
| Anna Maria Borruto, Claudia Calpe-López, Rainer Spanagel, Rick E Bernard. Conditional Deletion of the AMPA-GluA1 and NMDA-GluN1 Receptor Subunit Genes in Midbrain D1 Neurons does not Alter Cocaine Reward in Mice. Neuropharmacology. 2024-07-13. PMID:39002853. |
conditional deletion of the ampa-glua1 and nmda-glun1 receptor subunit genes in midbrain d1 neurons does not alter cocaine reward in mice. |
2024-07-13 |
2024-07-16 |
mouse |
| Stuart B Murray, Joel P Diaz-Fong, Vienna W T Mak, Jamie D Feusne. Assessing midbrain neuromelanin and its relationship to reward learning in anorexia nervosa: Stage 1 of a registered report. Brain and behavior. vol 14. issue 6. 2024-06-20. PMID:38898625. |
the assessment of midbrain neuromelanin, and its association with an psychopathology and reward-related processes, may provide critical insights into reward circuit function in an. |
2024-06-20 |
2024-06-22 |
Not clear |
| Eric Garr, Yifeng Cheng, Huijeong Jeong, Sara Brooke, Laia Castell, Aneesh Bal, Robin Magnard, Vijay Mohan K Namboodiri, Patricia H Jana. Mesostriatal dopamine is sensitive to changes in specific cue-reward contingencies. Science advances. vol 10. issue 22. 2024-05-29. PMID:38809978. |
conditioned responding was attenuated for the cue-reward contingency that was degraded, as was dopamine neuron activity in the midbrain and dopamine release in the ventral striatum in response to the cue and subsequent reward. |
2024-05-29 |
2024-06-02 |
rat |
| Wolfram Schult. A dopamine mechanism for reward maximization. Proceedings of the National Academy of Sciences of the United States of America. vol 121. issue 20. 2024-05-08. PMID:38717856. |
midbrain dopamine neurons code reward prediction errors (rpe) of subjective reward value suitable for rl. |
2024-05-08 |
2024-05-27 |
monkey |
| Yehong Fang, Yunkai Sun, Yi Liu, Tieqiao Liu, Wei Hao, Yanhui Lia. Neurobiological mechanisms and related clinical treatment of addiction: a review. Psychoradiology. vol 2. issue 4. 2024-04-26. PMID:38665277. |
the abnormal activity of the ventral tegmental, nucleus accumbens, and caudate nucleus in the binge/intoxication stage involve the reward circuit of the midbrain limbic system. |
2024-04-26 |
2024-04-28 |
Not clear |
| Ewa Galaj, Guo-Hua Bi, Zheng-Xiong X. β-caryophyllene inhibits heroin self-administration, but does not alter opioid-induced antinociception in rodents. Neuropharmacology. 2024-04-17. PMID:38631564. |
in this study, we found that systemic administration of bcp dose-dependently reduced heroin self-administration in rats under an fr2 schedule of reinforcement and partially blocked heroin-enhanced brain stimulation reward in dat-cre mice, maintained by optical stimulation of midbrain dopamine neurons at high frequencies. |
2024-04-17 |
2024-04-20 |
mouse |
| Guoqiang Hou, Mei Hao, Jiawen Duan, Ming-Hu Ha. The Formation and Function of the VTA Dopamine System. International journal of molecular sciences. vol 25. issue 7. 2024-04-13. PMID:38612683. |
the midbrain dopamine system is a sophisticated hub that integrates diverse inputs to control multiple physiological functions, including locomotion, motivation, cognition, reward, as well as maternal and reproductive behaviors. |
2024-04-13 |
2024-04-15 |
Not clear |
| Qingfang Liu, Yao Zhao, Sumedha Attanti, Joel L Voss, Geoffrey Schoenbaum, Thorsten Kahn. Midbrain signaling of identity prediction errors depends on orbitofrontal cortex networks. Nature communications. vol 15. issue 1. 2024-02-24. PMID:38402210. |
previous work across species has shown that the dopaminergic midbrain responds to violations in expected reward identity and that the lateral orbitofrontal cortex (ofc) represents reward identity expectations. |
2024-02-24 |
2024-02-27 |
Not clear |
| Qingfang Liu, Yao Zhao, Sumedha Attanti, Joel L Voss, Geoffrey Schoenbaum, Thorsten Kahn. Midbrain signaling of identity prediction errors depends on orbitofrontal cortex networks. Nature communications. vol 15. issue 1. 2024-02-24. PMID:38402210. |
critically, tms disrupted neural representations of expected reward identity in the ofc and modulated ipe responses in the midbrain. |
2024-02-24 |
2024-02-27 |
Not clear |
| Gail Tripp, Jeff Wicken. Using rodent data to elucidate dopaminergic mechanisms of ADHD: Implications for human personality. Personality neuroscience. vol 7. 2024-02-22. PMID:38384667. |
it is well known that midbrain dopamine neurons are initially activated by unexpected reward and gradually transfer their responses to reward-predicting cues. |
2024-02-22 |
2024-02-24 |
human |
| Borja Gomez Ramos, Jochen Ohnmacht, Nikola de Lange, Elena Valceschini, Aurélien Ginolhac, Marie Catillon, Daniele Ferrante, Aleksandar Rakovic, Rashi Halder, François Massart, Giuseppe Arena, Paul Antony, Silvia Bolognin, Christine Klein, Roland Krause, Marcel H Schulz, Thomas Sauter, Rejko Krüger, Lasse Sinkkone. Multiomics analysis identifies novel facilitators of human dopaminergic neuron differentiation. EMBO reports. 2024-01-04. PMID:38177910. |
midbrain dopaminergic neurons (mdans) control voluntary movement, cognition, and reward behavior under physiological conditions and are implicated in human diseases such as parkinson's disease (pd). |
2024-01-04 |
2024-01-07 |
human |
| S C Simmons, W J Flerlage, L D Langlois, R D Shepard, C Bouslog, E H Thomas, K M Gouty, J L Sanderson, S Gouty, B M Cox, M L Dell'Acqua, F S Nugen. AKAP150-anchored PKA regulation of synaptic transmission and plasticity, neuronal excitability and CRF neuromodulation in the lateral habenula. bioRxiv : the preprint server for biology. 2023-12-18. PMID:38106086. |
here we focused on an unexplored role of akap150 in the lateral habenula (lhb), a diencephalic brain region that integrates and relays negative reward signals from forebrain striatal and limbic structures to midbrain monoaminergic centers. |
2023-12-18 |
2023-12-21 |
mouse |