| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Daniel Medeiros, Débora Masini, Carina Plewnia, Laura Boi, Martha Rosati, Nicolas Scalbert, Gilberto Fison. Dopamine D2 receptor activation counteracts olfactory dysfunction and related cellular abnormalities in experimental parkinsonism. Heliyon. vol 10. issue 16. 2024-09-03. PMID:39224310. |
dopamine d2 receptor activation counteracts olfactory dysfunction and related cellular abnormalities in experimental parkinsonism. |
2024-09-03 |
2024-09-05 |
mouse |
| Daniel Medeiros, Débora Masini, Carina Plewnia, Laura Boi, Martha Rosati, Nicolas Scalbert, Gilberto Fison. Dopamine D2 receptor activation counteracts olfactory dysfunction and related cellular abnormalities in experimental parkinsonism. Heliyon. vol 10. issue 16. 2024-09-03. PMID:39224310. |
using this model, we investigated the effect of long-term, continuous administration of pramipexole, a dopamine d2/3 selective agonist, on olfactory dysfunction. |
2024-09-03 |
2024-09-05 |
mouse |
| Daniel Medeiros, Débora Masini, Carina Plewnia, Laura Boi, Martha Rosati, Nicolas Scalbert, Gilberto Fison. Dopamine D2 receptor activation counteracts olfactory dysfunction and related cellular abnormalities in experimental parkinsonism. Heliyon. vol 10. issue 16. 2024-09-03. PMID:39224310. |
moreover, they show that this protective effect is exerted in parallel to a normalization of dopamine neurons and beta band oscillations in the ob, providing information on the potential mechanisms involved in pd-related olfactory dysfunction. |
2024-09-03 |
2024-09-05 |
mouse |
| Divya Bharathi Selvaraj, Anusiya Panneerselvam, Jemi Feiona Vergil Andrews, Mahesh Kandasam. Cysteamine HCl Administration Impedes Motor and Olfactory Functions, Accompanied by a Reduced Number of Dopaminergic Neurons, in Experimental Mice: A Preclinical Mimetic Relevant to Parkinson's Disease. Brain sciences. vol 14. issue 7. 2024-07-27. PMID:39061373. |
cys-hcl has been shown to interfere with dopamine, a neurotransmitter crucial for motor, olfactory, and cognitive functions. |
2024-07-27 |
2024-07-29 |
mouse |
| Daichi Yamada, Andrew M Davidson, Toshihide Hig. Cyclic nucleotide-induced bidirectional long-term synaptic plasticity in Drosophila mushroom body. The Journal of physiology. 2024-03-15. PMID:38488688. |
key points: although presynaptic camp increase generally facilitates synapses, olfactory associative learning in drosophila, which depends on dopamine and camp signalling genes, induces long-term depression (ltd) at the mushroom body output synapses. |
2024-03-15 |
2024-03-17 |
drosophila_melanogaster |
| Ruidan Wang, Tenghong Lian, Mingyue He, Peng Guo, Shuyang Yu, Lijun Zuo, Yang Hu, Wei Zhan. Clinical features and neurobiochemical mechanisms of olfactory dysfunction in patients with Parkinson disease. Journal of neurology. 2023-12-27. PMID:38151574. |
dopamine and acetylcholine levels in csf were significantly and positively correlated with the scores of overall olfactory function, threshold, discrimination and identification in pd patients (p < 0.05). |
2023-12-27 |
2023-12-30 |
Not clear |
| Ariel M Lyons-Warren, Evelyne K Tantry, Elizabeth H Moss, Mikhail Y Kochukov, Benjamin D W Belfort, Joshua Ortiz-Guzman, Zachary Freyberg, Benjamin R Arenkie. Co-transmitting interneurons in the mouse olfactory bulb regulate olfactory detection and discrimination. Cell reports. vol 42. issue 12. 2023-11-19. PMID:37980561. |
here, we implement intersectional genetics in mice to selectively block gaba or dopamine release from superficial short-axon cells to identify their distinct cellular targets, impact on circuit function, and behavioral contribution of each neurotransmitter toward olfactory behaviors. |
2023-11-19 |
2023-11-29 |
mouse |
| Zahra Nazari, Khadijeh Bahrehbar, Soraya Ghafari, Mohammad Jafar Golalipou. Gestational diabetes mellitus increased the number of dopaminergic neurons in the olfactory bulb of rat offspring. Iranian journal of basic medical sciences. vol 26. issue 12. 2023-11-16. PMID:37970447. |
it has been demonstrated that dopamine modulates several aspects of olfactory information processing in vertebrates. |
2023-11-16 |
2023-11-20 |
rat |
| Suewei Li. Internal state-dependent modulation of olfactory responses: a tale of dopamine neurons in the adult Drosophila mushroom body. Current opinion in insect science. 2023-08-23. PMID:37611806. |
internal state-dependent modulation of olfactory responses: a tale of dopamine neurons in the adult drosophila mushroom body. |
2023-08-23 |
2023-09-07 |
drosophila_melanogaster |
| Woori Kim, Mohit Tripathi, Chunhyung Kim, Satyapavan Vardhineni, Young Cha, Shamseer Kulangara Kandi, Melissa Feitosa, Rohit Kholiya, Eric Sah, Anuj Thakur, Yehan Kim, Sanghyeok Ko, Kaiya Bhatia, Sunny Manohar, Young-Bin Kong, Gagandeep Sindhu, Yoon-Seong Kim, Bruce Cohen, Diwan S Rawat, Kwang-Soo Ki. An optimized Nurr1 agonist provides disease-modifying effects in Parkinson's disease models. Nature communications. vol 14. issue 1. 2023-07-18. PMID:37463889. |
in addition, 4a7c-301 protects midbrain dopamine neurons in the mptp-induced male mouse model of pd and improves both motor and non-motor olfactory deficits without dyskinesia-like behaviors. |
2023-07-18 |
2023-08-14 |
mouse |
| Adriana Trapani, Stefano Castellani, Lorenzo Guerra, Elvira De Giglio, Giuseppe Fracchiolla, Filomena Corbo, Nicola Cioffi, Giuseppe Passantino, Maria Luana Poeta, Pasqualina Montemurro, Rosanna Mallamaci, Rosa Angela Cardone, Massimo Cones. Combined Dopamine and Grape Seed Extract-Loaded Solid Lipid Nanoparticles: Nasal Mucosa Permeation, and Uptake by Olfactory Ensheathing Cells and Neuronal SH-SY5Y Cells. Pharmaceutics. vol 15. issue 3. 2023-03-29. PMID:36986742. |
combined dopamine and grape seed extract-loaded solid lipid nanoparticles: nasal mucosa permeation, and uptake by olfactory ensheathing cells and neuronal sh-sy5y cells. |
2023-03-29 |
2023-08-14 |
Not clear |
| Michael Marquis, Rachel I Wilso. Locomotor and olfactory responses in dopamine neurons of the Drosophila superior-lateral brain. Current biology : CB. 2022-11-30. PMID:36450284. |
locomotor and olfactory responses in dopamine neurons of the drosophila superior-lateral brain. |
2022-11-30 |
2023-08-14 |
drosophila_melanogaster |
| Pavan A Vaswani, James F Morley, Danna Jennings, Andrew Siderowf, Kenneth Mare. Serial olfactory testing for the diagnosis of prodromal Parkinson's disease in the PARS study. Parkinsonism & related disorders. vol 104. 2022-10-04. PMID:36194902. |
the parkinson associated risk syndrome (pars) study was designed to evaluate whether screening with olfactory testing and dopamine transporter (dat) imaging could identify participants at risk for developing parkinson's disease (pd). |
2022-10-04 |
2023-08-14 |
human |
| Vishnu Raj, Anoopkumar Thekkuveetti. Dopamine plays a critical role in the olfactory adaptive learning pathway in Caenorhabditis elegans. Journal of neuroscience research. 2022-07-30. PMID:35906758. |
dopamine plays a critical role in the olfactory adaptive learning pathway in caenorhabditis elegans. |
2022-07-30 |
2023-08-14 |
caenorhabditis_elegans |
| Shintaro Naganos, Kohei Ueno, Junjiro Horiuchi, Minoru Saito. Dopamine activity in projection neurons regulates short-lasting olfactory approach memory in Drosophila. The European journal of neuroscience. 2022-07-11. PMID:35815601. |
dopamine activity in projection neurons regulates short-lasting olfactory approach memory in drosophila. |
2022-07-11 |
2023-08-14 |
drosophila_melanogaster |
| Shintaro Naganos, Kohei Ueno, Junjiro Horiuchi, Minoru Saito. Dopamine activity in projection neurons regulates short-lasting olfactory approach memory in Drosophila. The European journal of neuroscience. 2022-07-11. PMID:35815601. |
in contrast to fear memories which are longer lasting and requires activity of d1-like dopamine receptors only in the mushroom bodies, approach memory is short-lasting, and requires activity of d1-like dopamine receptors in projection neurons originating from the antennal lobes, primary olfactory centers. |
2022-07-11 |
2023-08-14 |
drosophila_melanogaster |
| Olivier Rampin, Audrey Saint Albin Deliot, Christian Ouali, Jasmine Burguet, Elisa Gry, Gaelle Champeil Potokar, Nathalie Jérôme, Olga Davidenko, Nicolas Darcel, Vincent Bombail, Philippe Andrey, Isabelle Deni. Dopamine Modulates the Processing of Food Odour in the Ventral Striatum. Biomedicines. vol 10. issue 5. 2022-05-28. PMID:35625863. |
since the ventral striatum, at the crossroads of olfactory and reward pathways, receives a rich dopaminergic innervation, we hypothesized that dopamine plays a role in food odour information processing in the ventral striatum. |
2022-05-28 |
2023-08-13 |
rat |
| Darren J Byrne, Marcela Lipovsek, Andres Crespo, Matthew S Grub. Brief sensory deprivation triggers plasticity of dopamine-synthesising enzyme expression in genetically labelled olfactory bulb dopaminergic neurons. The European journal of neuroscience. 2022-05-05. PMID:35510299. |
here, instead, we used brief 1- or 3-day manipulations of olfactory experience in juvenile mice, coupled with a conditional genetic approach that labelled neurons contingent upon their expression of the dopamine transporter (dat-tdtomato). |
2022-05-05 |
2023-08-13 |
mouse |
| Fardin Nabizadeh, Fatemeh Sodeifian, Kasra Pirahes. Olfactory dysfunction and striatal dopamine transporter binding in motor subtypes of Parkinson's disease. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2022-05-04. PMID:35508569. |
olfactory dysfunction and striatal dopamine transporter binding in motor subtypes of parkinson's disease. |
2022-05-04 |
2023-08-13 |
Not clear |
| Fardin Nabizadeh, Fatemeh Sodeifian, Kasra Pirahes. Olfactory dysfunction and striatal dopamine transporter binding in motor subtypes of Parkinson's disease. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2022-05-04. PMID:35508569. |
there are contradictory results regarding the association of olfactory dysfunction and dopamine uptake in striatal nuclei among pd patients. |
2022-05-04 |
2023-08-13 |
Not clear |