| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shaojie Yang, Jiamin Hu, Yuzhuang Chen, Zhengrong Zhang, Jingji Wang, Guoqi Zh. DCC, a potential target for controlling fear memory extinction and hippocampal LTP in male mice receiving single prolonged stress. Neurobiology of stress. vol 32. 2024-09-03. PMID:39224830. |
dcc, a potential target for controlling fear memory extinction and hippocampal ltp in male mice receiving single prolonged stress. |
2024-09-03 |
2024-09-05 |
mouse |
| Shaojie Yang, Jiamin Hu, Yuzhuang Chen, Zhengrong Zhang, Jingji Wang, Guoqi Zh. DCC, a potential target for controlling fear memory extinction and hippocampal LTP in male mice receiving single prolonged stress. Neurobiology of stress. vol 32. 2024-09-03. PMID:39224830. |
specific overexpression of dcc in the hippocampus induced similar impairment of long-term potentiation (ltp) and fear memory extinction as observed in sps mice. |
2024-09-03 |
2024-09-05 |
mouse |
| Shaojie Yang, Jiamin Hu, Yuzhuang Chen, Zhengrong Zhang, Jingji Wang, Guoqi Zh. DCC, a potential target for controlling fear memory extinction and hippocampal LTP in male mice receiving single prolonged stress. Neurobiology of stress. vol 32. 2024-09-03. PMID:39224830. |
the impairment of fear memory extinction in sps mice was improved by inhibiting the function of hippocampal dcc using a neutralizing antibody. |
2024-09-03 |
2024-09-05 |
mouse |
| Shaojie Yang, Jiamin Hu, Yuzhuang Chen, Zhengrong Zhang, Jingji Wang, Guoqi Zh. DCC, a potential target for controlling fear memory extinction and hippocampal LTP in male mice receiving single prolonged stress. Neurobiology of stress. vol 32. 2024-09-03. PMID:39224830. |
mechanistic studies have shown that knocking down or inhibiting μ-calpain in hippocampal neurons increased dcc expression and induced impairment of fear memory extinction. |
2024-09-03 |
2024-09-05 |
mouse |
| Shaojie Yang, Jiamin Hu, Yuzhuang Chen, Zhengrong Zhang, Jingji Wang, Guoqi Zh. DCC, a potential target for controlling fear memory extinction and hippocampal LTP in male mice receiving single prolonged stress. Neurobiology of stress. vol 32. 2024-09-03. PMID:39224830. |
additionally, sps-triggered impairment of hippocampal ltp and fear memory extinction could be rescued through activation of the rac1-pak1 signaling pathway. |
2024-09-03 |
2024-09-05 |
mouse |
| Shaojie Yang, Jiamin Hu, Yuzhuang Chen, Zhengrong Zhang, Jingji Wang, Guoqi Zh. DCC, a potential target for controlling fear memory extinction and hippocampal LTP in male mice receiving single prolonged stress. Neurobiology of stress. vol 32. 2024-09-03. PMID:39224830. |
our study provides evidence that calpain-mediated regulation of dcc controls hippocampal ltp and fear memory extinction in sps mice, which likely through activation of the rac1-pak1 signaling pathway. |
2024-09-03 |
2024-09-05 |
mouse |
| Megha Maheshwari, Aastha Singla, Anoop Rawat, Toshali Banerjee, Sthitapranjya Pati, Sneha Shah, Sudipta Maiti, Vidita A Vaidy. Chronic chemogenetic activation of hippocampal progenitors enhances adult neurogenesis and modulates anxiety-like behavior and fear extinction learning. IBRO neuroscience reports. vol 16. 2024-07-16. PMID:39007086. |
furthermore, we noted an enhanced fear memory extinction on a contextual fear memory learning task in transgenic mice subjected to chemogenetic activation of adult hippocampal progenitors. |
2024-07-16 |
2024-07-18 |
mouse |
| Megha Maheshwari, Aastha Singla, Anoop Rawat, Toshali Banerjee, Sthitapranjya Pati, Sneha Shah, Sudipta Maiti, Vidita A Vaidy. Chronic chemogenetic activation of hippocampal progenitors enhances adult neurogenesis and modulates anxiety-like behavior and fear extinction learning. IBRO neuroscience reports. vol 16. 2024-07-16. PMID:39007086. |
our findings indicate that hm3dq-dread-mediated chemogenetic activation of adult hippocampal progenitors impacts distinct aspects of hippocampal neurogenesis, associated with the regulation of anxiety-like behavior and fear memory extinction. |
2024-07-16 |
2024-07-18 |
mouse |
| Kenichi Oga, Manabu Fuchikami, Hironori Kobayashi, Tatsuhiro Miyagi, Sho Fujita, Satoshi Fujita, Satoshi Okada, Shigeru Morinob. Involvement of dysregulated hippocampal histone H3K9 methylation at the promoter of the BDNF gene in impaired memory extinction. Psychopharmacology. 2024-06-28. PMID:38940908. |
involvement of dysregulated hippocampal histone h3k9 methylation at the promoter of the bdnf gene in impaired memory extinction. |
2024-06-28 |
2024-06-30 |
Not clear |
| Karine Ramires Lima, Niege Alves, Luiza Freitas Lopes, Steffanie Severo Picua, Liane da Silva de Vargas, Leticia Rossi Daré, Bruna Ramborger, Rafael Roehrs, Marcelo Gomes de Gomes, Pâmela Billig Mello-Carpe. Novelty facilitates the persistence of aversive memory extinction by dopamine regulation in the hippocampus and ventral tegmental area. Progress in neuro-psychopharmacology & biological psychiatry. 2023-07-18. PMID:37463639. |
novelty facilitates the persistence of aversive memory extinction by dopamine regulation in the hippocampus and ventral tegmental area. |
2023-07-18 |
2023-08-14 |
rat |
| Ana Elena Teleuca, Giovanni Sebastiano Alemà, Paola Casolini, Ilaria Barberis, Francesco Ciabattoni, Rosamaria Orlando, Luisa Di Menna, Luisa Iacovelli, Maria Rosaria Scioli, Ferdinando Nicoletti, Anna Rita Zuen. Changes in mGlu5 Receptor Signaling Are Associated with Associative Learning and Memory Extinction in Mice. Life (Basel, Switzerland). vol 12. issue 3. 2022-03-25. PMID:35330215. |
using an in vivo method for the assessment of polyphosphoinositide (pi) hydrolysis, we examine whether spatial learning and memory extinction cause changes in mglu5 metabotropic glutamate receptor signaling in the hippocampus and prefrontal cortex. |
2022-03-25 |
2023-08-13 |
mouse |
| Ana Elena Teleuca, Giovanni Sebastiano Alemà, Paola Casolini, Ilaria Barberis, Francesco Ciabattoni, Rosamaria Orlando, Luisa Di Menna, Luisa Iacovelli, Maria Rosaria Scioli, Ferdinando Nicoletti, Anna Rita Zuen. Changes in mGlu5 Receptor Signaling Are Associated with Associative Learning and Memory Extinction in Mice. Life (Basel, Switzerland). vol 12. issue 3. 2022-03-25. PMID:35330215. |
memory extinction was associated with a large up-regulation of mglu5 receptor-mediated pi hydrolysis in the three brain regions and with increases in mglu5 receptor and phospholipase-cβ protein levels in the ventral and dorsal hippocampus, respectively. |
2022-03-25 |
2023-08-13 |
mouse |
| Amir Bazaz, Ali Ghanbari, Abbas Ali Vafaei, Ali Khaleghian, Ali Rashidy-Pou. Oxytocin in dorsal hippocampus facilitates auditory fear memory extinction in rats. Neuropharmacology. vol 202. 2021-11-26. PMID:34687711. |
oxytocin in dorsal hippocampus facilitates auditory fear memory extinction in rats. |
2021-11-26 |
2023-08-13 |
rat |
| João Vitor Ferreira Rodrigues, Anna Paula Perin Vidigal, Vítor Sampaio Minassa, Thatiany Jardim Batista, Randriely Merscher Sobreira de Lima, Vinícius Rafael Funck, Leandro S Antero, Leonardo Barbosa Moraes Resstel, Juliana Barbosa Coitinho, Leandro Jose Bertoglio, Karla Nívea Sampaio, Vanessa Beijamin. A single dose of the organophosphate triazophos induces fear extinction deficits accompanied by hippocampal acetylcholinesterase inhibition. Neurotoxicology and teratology. vol 82. 2021-09-23. PMID:33031921. |
our findings suggest that fear memory extinction deficits induced by acute triazophos intoxication are accompanied by hippocampal ache inhibition. |
2021-09-23 |
2023-08-13 |
rat |
| Toshiaki Ishii, Hidefumi Furuoka, Motohiro Kaya, Tetsuya Kuhar. Oral Administration of Probiotic Biomedicines. vol 9. issue 2. 2021-03-16. PMID:33567772. |
oral administration of probiotic we previously reported that 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinson's disease (pd) model mice (pd mice) facilitate hippocampal memory extinction, which may be the cause of cognitive impairment in pd. |
2021-03-16 |
2023-08-13 |
mouse |
| Xavier Yerna, Olivier Schakman, Ikram Ratbi, Anna Kreis, Sophie Lepannetier, Marie de Clippele, Younès Achouri, Nicolas Tajeddine, Fadel Tissir, Roberta Gualdani, Philippe Gaill. Role of the TRPC1 Channel in Hippocampal Long-Term Depression and in Spatial Memory Extinction. International journal of molecular sciences. vol 21. issue 5. 2020-12-08. PMID:32138218. |
role of the trpc1 channel in hippocampal long-term depression and in spatial memory extinction. |
2020-12-08 |
2023-08-13 |
Not clear |
| Toshiaki Ishii, Ken-Ichi Kinoshita, Yoshikage Muro. Serotonin 5-HT International journal of molecular sciences. vol 20. issue 21. 2020-04-13. PMID:31717815. |
serotonin 5-ht previously, we found that 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp)-induced parkinson's disease (pd) model mice (pd mice) showed facilitation of hippocampal memory extinction via reduced cyclic adenosine monophosphate (camp)/camp-dependent response element-binding protein (creb) signaling, which may cause cognitive impairment in pd. |
2020-04-13 |
2023-08-13 |
mouse |
| Ulrika Wilhelmsson, Andrea Pozo-Rodrigalvarez, Marie Kalm, Yolanda de Pablo, Åsa Widestrand, Marcela Pekna, Milos Pekn. The role of GFAP and vimentin in learning and memory. Biological chemistry. vol 400. issue 9. 2020-02-17. PMID:31063456. |
while the locomotion, exploratory behavior and learning of gfap-/-vim-/- mice, as assessed by object recognition, the morris water maze, and trace fear conditioning tests, were comparable to wildtype mice, gfap-/-vim-/- mice showed more pronounced memory extinction when tested in intellicages, a finding compatible with the scenario of an increased rate of reorganization of the hippocampal circuitry. |
2020-02-17 |
2023-08-13 |
mouse |
| Crhistian Luis Bender, Marcelo Giachero, Ramiro Comas-Mutis, Victor Alejandro Molina, Gastón Diego Calf. Stress influences the dynamics of hippocampal structural remodeling associated with fear memory extinction. Neurobiology of learning and memory. vol 155. 2019-09-23. PMID:30195049. |
stress influences the dynamics of hippocampal structural remodeling associated with fear memory extinction. |
2019-09-23 |
2023-08-13 |
rat |
| Pablo Mendez, Thomas Stefanelli, Carmen E Flores, Dominique Muller, Christian Lüsche. Homeostatic Plasticity in the Hippocampus Facilitates Memory Extinction. Cell reports. vol 22. issue 6. 2019-05-20. PMID:29425501. |
homeostatic plasticity in the hippocampus facilitates memory extinction. |
2019-05-20 |
2023-08-13 |
Not clear |