| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shaojie Yang, Jiamin Hu, Yuzhuang Chen, Zhengrong Zhang, Jingji Wang, Guoqi Zh. DCC, a potential target for controlling fear memory extinction and hippocampal LTP in male mice receiving single prolonged stress. Neurobiology of stress. vol 32. 2024-09-03. PMID:39224830. |
specific overexpression of dcc in the hippocampus induced similar impairment of long-term potentiation (ltp) and fear memory extinction as observed in sps mice. |
2024-09-03 |
2024-09-05 |
mouse |
| Shaojie Yang, Jiamin Hu, Yuzhuang Chen, Zhengrong Zhang, Jingji Wang, Guoqi Zh. DCC, a potential target for controlling fear memory extinction and hippocampal LTP in male mice receiving single prolonged stress. Neurobiology of stress. vol 32. 2024-09-03. PMID:39224830. |
mechanistic studies have shown that knocking down or inhibiting μ-calpain in hippocampal neurons increased dcc expression and induced impairment of fear memory extinction. |
2024-09-03 |
2024-09-05 |
mouse |
| Shaojie Yang, Jiamin Hu, Yuzhuang Chen, Zhengrong Zhang, Jingji Wang, Guoqi Zh. DCC, a potential target for controlling fear memory extinction and hippocampal LTP in male mice receiving single prolonged stress. Neurobiology of stress. vol 32. 2024-09-03. PMID:39224830. |
dcc, a potential target for controlling fear memory extinction and hippocampal ltp in male mice receiving single prolonged stress. |
2024-09-03 |
2024-09-05 |
mouse |
| Shaojie Yang, Jiamin Hu, Yuzhuang Chen, Zhengrong Zhang, Jingji Wang, Guoqi Zh. DCC, a potential target for controlling fear memory extinction and hippocampal LTP in male mice receiving single prolonged stress. Neurobiology of stress. vol 32. 2024-09-03. PMID:39224830. |
our study provides evidence that calpain-mediated regulation of dcc controls hippocampal ltp and fear memory extinction in sps mice, which likely through activation of the rac1-pak1 signaling pathway. |
2024-09-03 |
2024-09-05 |
mouse |
| Shaojie Yang, Jiamin Hu, Yuzhuang Chen, Zhengrong Zhang, Jingji Wang, Guoqi Zh. DCC, a potential target for controlling fear memory extinction and hippocampal LTP in male mice receiving single prolonged stress. Neurobiology of stress. vol 32. 2024-09-03. PMID:39224830. |
the impairment of fear memory extinction in sps mice was improved by inhibiting the function of hippocampal dcc using a neutralizing antibody. |
2024-09-03 |
2024-09-05 |
mouse |