| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shaojie Yang, Jiamin Hu, Yuzhuang Chen, Zhengrong Zhang, Jingji Wang, Guoqi Zh. DCC, a potential target for controlling fear memory extinction and hippocampal LTP in male mice receiving single prolonged stress. Neurobiology of stress. vol 32. 2024-09-03. PMID:39224830. |
dcc, a potential target for controlling fear memory extinction and hippocampal ltp in male mice receiving single prolonged stress. |
2024-09-03 |
2024-09-05 |
mouse |
| Shaojie Yang, Jiamin Hu, Yuzhuang Chen, Zhengrong Zhang, Jingji Wang, Guoqi Zh. DCC, a potential target for controlling fear memory extinction and hippocampal LTP in male mice receiving single prolonged stress. Neurobiology of stress. vol 32. 2024-09-03. PMID:39224830. |
post-traumatic stress disorder (ptsd) is a severe stress-dependent psychiatric disorder characterized by impairment of fear memory extinction; however, biological markers to determine impaired fear memory extinction in ptsd remain unclear. |
2024-09-03 |
2024-09-05 |
mouse |
| Shaojie Yang, Jiamin Hu, Yuzhuang Chen, Zhengrong Zhang, Jingji Wang, Guoqi Zh. DCC, a potential target for controlling fear memory extinction and hippocampal LTP in male mice receiving single prolonged stress. Neurobiology of stress. vol 32. 2024-09-03. PMID:39224830. |
specific overexpression of dcc in the hippocampus induced similar impairment of long-term potentiation (ltp) and fear memory extinction as observed in sps mice. |
2024-09-03 |
2024-09-05 |
mouse |
| Shaojie Yang, Jiamin Hu, Yuzhuang Chen, Zhengrong Zhang, Jingji Wang, Guoqi Zh. DCC, a potential target for controlling fear memory extinction and hippocampal LTP in male mice receiving single prolonged stress. Neurobiology of stress. vol 32. 2024-09-03. PMID:39224830. |
the impairment of fear memory extinction in sps mice was improved by inhibiting the function of hippocampal dcc using a neutralizing antibody. |
2024-09-03 |
2024-09-05 |
mouse |
| Shaojie Yang, Jiamin Hu, Yuzhuang Chen, Zhengrong Zhang, Jingji Wang, Guoqi Zh. DCC, a potential target for controlling fear memory extinction and hippocampal LTP in male mice receiving single prolonged stress. Neurobiology of stress. vol 32. 2024-09-03. PMID:39224830. |
mechanistic studies have shown that knocking down or inhibiting μ-calpain in hippocampal neurons increased dcc expression and induced impairment of fear memory extinction. |
2024-09-03 |
2024-09-05 |
mouse |
| Shaojie Yang, Jiamin Hu, Yuzhuang Chen, Zhengrong Zhang, Jingji Wang, Guoqi Zh. DCC, a potential target for controlling fear memory extinction and hippocampal LTP in male mice receiving single prolonged stress. Neurobiology of stress. vol 32. 2024-09-03. PMID:39224830. |
additionally, sps-triggered impairment of hippocampal ltp and fear memory extinction could be rescued through activation of the rac1-pak1 signaling pathway. |
2024-09-03 |
2024-09-05 |
mouse |
| Shaojie Yang, Jiamin Hu, Yuzhuang Chen, Zhengrong Zhang, Jingji Wang, Guoqi Zh. DCC, a potential target for controlling fear memory extinction and hippocampal LTP in male mice receiving single prolonged stress. Neurobiology of stress. vol 32. 2024-09-03. PMID:39224830. |
our study provides evidence that calpain-mediated regulation of dcc controls hippocampal ltp and fear memory extinction in sps mice, which likely through activation of the rac1-pak1 signaling pathway. |
2024-09-03 |
2024-09-05 |
mouse |
| Megha Maheshwari, Aastha Singla, Anoop Rawat, Toshali Banerjee, Sthitapranjya Pati, Sneha Shah, Sudipta Maiti, Vidita A Vaidy. Chronic chemogenetic activation of hippocampal progenitors enhances adult neurogenesis and modulates anxiety-like behavior and fear extinction learning. IBRO neuroscience reports. vol 16. 2024-07-16. PMID:39007086. |
furthermore, we noted an enhanced fear memory extinction on a contextual fear memory learning task in transgenic mice subjected to chemogenetic activation of adult hippocampal progenitors. |
2024-07-16 |
2024-07-18 |
mouse |
| Megha Maheshwari, Aastha Singla, Anoop Rawat, Toshali Banerjee, Sthitapranjya Pati, Sneha Shah, Sudipta Maiti, Vidita A Vaidy. Chronic chemogenetic activation of hippocampal progenitors enhances adult neurogenesis and modulates anxiety-like behavior and fear extinction learning. IBRO neuroscience reports. vol 16. 2024-07-16. PMID:39007086. |
our findings indicate that hm3dq-dread-mediated chemogenetic activation of adult hippocampal progenitors impacts distinct aspects of hippocampal neurogenesis, associated with the regulation of anxiety-like behavior and fear memory extinction. |
2024-07-16 |
2024-07-18 |
mouse |
| Chinatsu Kawakami, Toshie Naoi, Masanori Sakaguch. Spaced conditioned stimulus presentation facilitates the extinction of strong fear memory in mice. Biochemical and biophysical research communications. vol 718. 2024-05-12. PMID:38735136. |
inducing fear memory extinction by re-presenting a conditioned stimulus (cs) is the foundation of exposure therapy for post-traumatic stress disorder (ptsd). |
2024-05-12 |
2024-05-27 |
mouse |
| Laura Luyten, Anastasia Chalkia, Anna Elisabeth Schnell, Burcu Özcan, Lu Leng, Natalie Schroyens, Lukas Van Oudenhove, Wolf Vanpaemel, Tom Becker. No harmful effect of propranolol administered prior to fear memory extinction in rats and humans. Journal of anxiety disorders. vol 104. 2024-05-11. PMID:38733644. |
no harmful effect of propranolol administered prior to fear memory extinction in rats and humans. |
2024-05-11 |
2024-05-27 |
human |
| Kosuke Enomoto, Kazuro Shibata, Hiroyuki Muraoka, Masahiko Kawano, Ken Inada, Jun Ishigooka, Katsuji Nishimura, Hidehiro Oshibuch. Effects of chronic haloperidol treatment on the expression of fear memory and fear memory extinction in the cued fear-conditioned rats. Neuropsychopharmacology reports. 2024-02-15. PMID:38356296. |
effects of chronic haloperidol treatment on the expression of fear memory and fear memory extinction in the cued fear-conditioned rats. |
2024-02-15 |
2024-02-17 |
rat |
| Matthew J Jones, Taygun C Uzuneser, Timothy Clement, Hehe Wang, Iwao Ojima, Walter J Rushlow, Steven R Laviolett. Inhibition of fatty acid binding protein-5 in the basolateral amygdala induces anxiolytic effects and accelerates fear memory extinction. Psychopharmacology. 2023-09-25. PMID:37747506. |
inhibition of fatty acid binding protein-5 in the basolateral amygdala induces anxiolytic effects and accelerates fear memory extinction. |
2023-09-25 |
2023-10-07 |
Not clear |
| Xuansheng Xiao, Xiaotong Wang, Ke Zhu, Lijuan Li, Ying He, Jinglan Zhang, Linying Li, Hanning Hu, Yanqiu Cui, Jianliang Zhang, Yan Zhen. BACE1 in PV interneuron tunes hippocampal CA1 local circuits and resets priming of fear memory extinction. Molecular psychiatry. 2023-07-14. PMID:37452089. |
bace1 in pv interneuron tunes hippocampal ca1 local circuits and resets priming of fear memory extinction. |
2023-07-14 |
2023-08-14 |
mouse |
| Xuansheng Xiao, Xiaotong Wang, Ke Zhu, Lijuan Li, Ying He, Jinglan Zhang, Linying Li, Hanning Hu, Yanqiu Cui, Jianliang Zhang, Yan Zhen. BACE1 in PV interneuron tunes hippocampal CA1 local circuits and resets priming of fear memory extinction. Molecular psychiatry. 2023-07-14. PMID:37452089. |
above all, the bace1 deletion resets the priming of the fear memory extinction. |
2023-07-14 |
2023-08-14 |
mouse |
| Morvarid Meamar, Ali Rashidy-Pour, Mehrnoush Rahmani, Abbas Ali Vafaei, Payman Raise-Abdullah. Glucocorticoid- β-adrenoceptors interactions in the infralimbic cortex in acquisition and consolidation of auditory fear memory extinction in rats. Pharmacology, biochemistry, and behavior. 2023-04-24. PMID:37094708. |
glucocorticoid- β-adrenoceptors interactions in the infralimbic cortex in acquisition and consolidation of auditory fear memory extinction in rats. |
2023-04-24 |
2023-08-14 |
rat |
| Morvarid Meamar, Ali Rashidy-Pour, Mehrnoush Rahmani, Abbas Ali Vafaei, Payman Raise-Abdullah. Glucocorticoid- β-adrenoceptors interactions in the infralimbic cortex in acquisition and consolidation of auditory fear memory extinction in rats. Pharmacology, biochemistry, and behavior. 2023-04-24. PMID:37094708. |
intra-il injection of corticosterone (cort, 20 ng/0.5 μl per side) before ext 1 and after ext 1-2, respectively, facilitated the acquisition and consolidation of fear memory extinction. |
2023-04-24 |
2023-08-14 |
rat |
| Samira Omoumi, Ali Rashidy-Pour, Seyed Ali Seyedinia, Parnia Tarahomi, Abbas Ali Vafaei, Payman Raise-Abdullah. Corticosterone injection into the infralimbic prefrontal cortex enhances fear memory extinction: Involvement of GABA receptors and the extracellular signal-regulated kinase. Physiology & behavior. 2023-03-14. PMID:36918107. |
corticosterone injection into the infralimbic prefrontal cortex enhances fear memory extinction: involvement of gaba receptors and the extracellular signal-regulated kinase. |
2023-03-14 |
2023-08-14 |
rat |
| Samira Omoumi, Ali Rashidy-Pour, Seyed Ali Seyedinia, Parnia Tarahomi, Abbas Ali Vafaei, Payman Raise-Abdullah. Corticosterone injection into the infralimbic prefrontal cortex enhances fear memory extinction: Involvement of GABA receptors and the extracellular signal-regulated kinase. Physiology & behavior. 2023-03-14. PMID:36918107. |
intra-il injection of corticosterone (cort, 20 ng/0.3µl/side) was performed 15 min before the first extinction trial (ext 1) which attenuated auditory fear expression in subsequent extinction trials (ext 1-3), demonstrating fear memory extinction enhancement. |
2023-03-14 |
2023-08-14 |
rat |
| Ahmad Mohammadi-Farani, Sajad Farhangian, Samira Shirooi. Sex differences in acetylcholinesterase modulation during spatial and fear memory extinction in the amygdala; an animal study in the single prolonged stress model of PTSD. Research in pharmaceutical sciences. vol 17. issue 6. 2023-01-27. PMID:36704427. |
sex differences in acetylcholinesterase modulation during spatial and fear memory extinction in the amygdala; an animal study in the single prolonged stress model of ptsd. |
2023-01-27 |
2023-08-14 |
rat |