| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kenta Kato, Hirofumi Tomiyama, Keitaro Murayama, Taro Mizobe, Akira Matsuo, Nami Nishida, Kou Matukuma, Mingi Kang, Kenta Sashikata, Kazufumi Kikuchi, Osamu Togao, Tomohiro Naka. Reduced resting-state functional connectivity between insula and inferior frontal gyrus and superior temporal gyrus in hoarding disorder. Frontiers in psychiatry. vol 15. 2024-07-06. PMID:38966185. |
hoarding disorder (hd) is characterized by cognitive control impairments and abnormal brain activity in the insula and anterior cingulate cortex (acc) during disposal of personal items or certain executive function tasks. |
2024-07-06 |
2024-07-08 |
Not clear |
| Blaise L Worden, David F Tolin, Michael C Steven. An exploration of neural predictors of treatment compliance in cognitive-behavioral group therapy for hoarding disorder. Journal of affective disorders. vol 345. 2024-05-06. PMID:38706461. |
recent research has suggested that hd patients have abnormal brain activity identified by functional magnetic resonance (fmri) in regions often engaged for executive functioning (e.g., right superior frontal gyrus, anterior insula, and anterior cingulate), which raises questions about whether these abnormalities could relate to patients' ability to attend, understand, and engage in hd treatment. |
2024-05-06 |
2024-05-08 |
Not clear |
| A T Funk, Aao Hassan, J L Waug. In humans, insulo-striate structural connectivity is largely biased toward either striosome-like or matrix-like striatal compartments. bioRxiv : the preprint server for biology. 2024-04-22. PMID:38645229. |
the insula is an integral component of sensory, motor, limbic, and executive functions, and insular dysfunction is associated with numerous human neuropsychiatric disorders. |
2024-04-22 |
2024-04-24 |
human |
| Mathias L Mathiasen, John P Aggleton, Menno P Witte. Projections of the insular cortex to orbitofrontal and medial prefrontal cortex: A tracing study in the rat. Frontiers in neuroanatomy. vol 17. 2023-05-08. PMID:37152205. |
the dense fiber pathways that connect the insular cortex with frontal cortices are thought to provide these frontal areas with interoceptive information, crucial for their involvement in executive functions. |
2023-05-08 |
2023-08-14 |
rat |
| Katharina M Rischer, Fernand Anton, Ana M González-Roldán, Pedro Montoya, Marian van der Meule. Better Executive Functions Are Associated With More Efficient Cognitive Pain Modulation in Older Adults: An fMRI Study. Frontiers in aging neuroscience. vol 14. 2022-07-25. PMID:35875790. |
covariate analyses indicated that executive functions significantly predicted neural pain modulation in older adults: better executive functions were associated with a more pronounced de-activation of the insula, thalamus and primary somatosensory cortex and increased activation of prefrontal regions during the high vs. low load task. |
2022-07-25 |
2023-08-14 |
human |
| Teresa G Vargas, Katherine S F Damme, Vijay A Mitta. Differentiating distinct and converging neural correlates of types of systemic environmental exposures. Human brain mapping. 2022-01-22. PMID:35064714. |
self-report (|β| = .04-.09) and objective (|β| = .02-.06) environmental domains related to area/thickness in overlapping (e.g., insula, caudal anterior cingulate), and unique regions (e.g., for discrepancy, rostral anterior and isthmus cingulate, implicated in socioemotional functions; for stimulation, precuneus, critical for cue reactivity and integration of environmental cues; and for deprivation, superior frontal, integral to executive functioning). |
2022-01-22 |
2023-08-13 |
Not clear |
| Rajikha Raja, Xiaoxu Na, Charles M Glasier, Thomas M Badger, Jayne Bellando, Xiawei O. Associations between Cortical Asymmetry and Domain Specific Cognitive Functions in Healthy Children. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2021. 2021-12-11. PMID:34891904. |
specifically, sli of total surface area of precuneus and insula significantly correlated with measures of executive function behavior; significant relationships were also found between sli of mean cortical thickness of superior parietal cortex and memory and language tests scores; in addition, sli of parahippocampal gyrus also showed significant correlations with language test scores for all 3 morphometry features. |
2021-12-11 |
2023-08-13 |
human |
| Georgina Spies, Fatima Ahmed-Leitao, Graeme Hoddinott, Soraya Seeda. Effects of unhealthy alcohol use on brain morphometry and neurocognitive function among people with HIV. Journal of neurovirology. 2021-12-09. PMID:34882280. |
homogeneity of slopes ancova revealed significant associations between anterior cingulate cortex, precuneus, amygdala, hippocampus, and insula volumes and cognitive function in the domains of learning and delayed recall, motor function, speed of information processing, executive function, attention/working memory, and language. |
2021-12-09 |
2023-08-13 |
Not clear |
| Yuanyuan Guo, Xinyi Lv, Qiang Wei, Yue Wu, Yue Chen, Yang Ji, Qiangqiang Hou, Huaming Lv, Nong Zhou, Kai Wang, Yanghua Tia. Impaired neurovascular coupling and cognitive deficits in anti-N-methyl-D-aspartate receptor encephalitis. Brain imaging and behavior. 2021-11-04. PMID:34735667. |
reduced cbf‒reho in the left superior medial frontal gyrus of patients was significantly correlated with a deficit in verbal inhibition control, and the reduced cbf‒reho in the left insula was significantly correlated with impaired executive function. |
2021-11-04 |
2023-08-13 |
Not clear |
| Melanie A Matyi, Sebastian M Cioaba, Marie T Banich, Jeffrey M Spielber. Identifying brain regions supporting amygdalar functionality: Application of a novel graph theory technique. NeuroImage. vol 244. 2021-11-01. PMID:34571162. |
other regions identified span basic (e.g., visual cortex) to higher-order (e.g., insula) sensory processing and executive functions (e.g., dorsolateral prefrontal cortex). |
2021-11-01 |
2023-08-13 |
Not clear |
| Jan-Patrick Stellmann, Nadine Wanke, Adil Maarouf, Susanne Gellißen, Christoph Heesen, Bertrand Audoin, Stefan M Gold, Wafaa Zaaraoui, Jana Poettge. Cognitive performance shows domain specific associations with regional cortical thickness in multiple sclerosis. NeuroImage. Clinical. vol 30. 2021-07-30. PMID:33744503. |
cortical regions associated with multiple cognitive tasks in the left hemisphere were predominantly located in the inferior insula (attention p < 0.001, memory p = 0.047, spatial processing p = 0.004, executive functioning p = 0.037), the gyrus frontalis superior (attention p = 0.015, memory p = 0.037, spatial processing p = 0.033, executive functioning p = 0.017) and temporal medial (attention p < 0.001, memory two clusters p = 0.016 and p < 0.001, executive functioning p = 0.016). |
2021-07-30 |
2023-08-13 |
Not clear |
| b' Mia Haaranen, Giulia Scuppa, Stefano Tambalo, Vilja J\\xc3\\xa4rvi, Sine M Bertozzi, Andrea Armirotti, Wolfgang H Sommer, Angelo Bifone, Petri Hyyti\\xc3\\xa. Anterior insula stimulation suppresses appetitive behavior while inducing forebrain activation in alcohol-preferring rats. Translational psychiatry. vol 10. issue 1. 2021-06-18. PMID:32424183.' |
the anterior insular cortex plays a key role in the representation of interoceptive effects of drug and natural rewards and their integration with attention, executive function, and emotions, making it a potential target region for intervention to control appetitive behaviors. |
2021-06-18 |
2023-08-13 |
rat |
| Ziv Ben-Zion, Yoav Zeevi, Nimrod Jackob Keynan, Roee Admon, Tal Kozlovski, Haggai Sharon, Pinchas Halpern, Israel Liberzon, Arieh Y Shalev, Yoav Benjamini, Talma Hendle. Multi-domain potential biomarkers for post-traumatic stress disorder (PTSD) severity in recent trauma survivors. Translational psychiatry. vol 10. issue 1. 2021-06-18. PMID:32594097. |
results revealed that entorhinal and rostral anterior cingulate cortices volumes (structural mri domain), in-task amygdala's functional connectivity with the insula and thalamus (functional mri domain), executive function and cognitive flexibility (cognitive testing domain) best differentiated between two clusters associated with ptsd severity. |
2021-06-18 |
2023-08-13 |
human |
| Amanda R Pahng, M Adrienne McGinn, Rod I Paulsen, Scott Edward. The Prefrontal Cortex as a Critical Gate of Negative Affect and Motivation in Alcohol Use Disorder. Current opinion in behavioral sciences. vol 13. 2020-10-01. PMID:28111628. |
several cognitive symptoms commonly associated with severe aud, ranging from poor risk management to the cognitive/affective dimension of pain, are likely mediated by altered function of key anatomical elements that modulate pfc executive function, including contributions from the cingulate cortex and insula. |
2020-10-01 |
2023-08-13 |
Not clear |
| Andreia V Faria, Jeffrey Crawford, Chenfei Ye, Johnny Hsu, Anshel Kenkare, David Schretlen, Akira Saw. Relationship between neuropsychological behavior and brain white matter in first-episode psychosis. Schizophrenia research. vol 208. 2020-08-03. PMID:30987924. |
regionally specific correlations were found in fep between three specific domains of cognition (processing speed, attention/working memory, and executive functioning) and fa at the deep (cerebral peduncles, sagittal striatum, uncinate, internal/external capsule, cingulum) and peripheral white matter (adjacent to inferior temporal, angular, supramarginal, insula, occipital, rectus gyrus). |
2020-08-03 |
2023-08-13 |
Not clear |
| Lucia M Li, Ines R Violante, Karl Zimmerman, Rob Leech, Adam Hampshire, Maneesh Patel, Alexander Opitz, David McArthur, Amy Jolly, David W Carmichael, David J Shar. Traumatic axonal injury influences the cognitive effect of non-invasive brain stimulation. Brain : a journal of neurology. vol 142. issue 10. 2020-06-15. PMID:31504237. |
stimulation was applied to the right inferior frontal gyrus/anterior insula node of the salience network, which was targeted because our previous work had shown its importance to executive function. |
2020-06-15 |
2023-08-13 |
human |
| Lauren E Sherman, Gail M Rosenbaum, Ashley R Smith, Morgan A Botdorf, Karla Fettich, Jamie L Patrianakos, Michael McCloskey, Laurence D Steinberg, Jason M Chei. The interactive effects of peers and alcohol on functional brain connectivity in young adults. NeuroImage. vol 197. 2020-02-10. PMID:30978496. |
intoxicated participants made more mistakes on go/no-go, and showed diminished connectivity between the anterior insular cortex (aic) and regions implicated in executive function (e.g., dorsal anterior cingulate). |
2020-02-10 |
2023-08-13 |
human |
| Gioele Gavazzi, Stefano Orsolini, Emilia Salvadori, Andrea Bianchi, Arianna Rossi, Ida Donnini, Valentina Rinnoci, Francesca Pescini, Stefano Diciotti, Maria Pia Viggiano, Mario Mascalchi, Leonardo Panton. Functional Magnetic Resonance Imaging of Inhibitory Control Reveals Decreased Blood Oxygen Level Dependent Effect in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy. Stroke. 2019-11-20. PMID:30580728. |
analysis of the proactive inhibition (alertness contrast) in cadasil patients revealed a lower blood oxygen level dependent effect in the alerting network (anterior cingulate cortex and insula, thalamus), lower brain stem and left cerebellar hemisphere (crus i) that is involved in executive functions. |
2019-11-20 |
2023-08-13 |
Not clear |
| Chao Wang, Peiyu Huang, Zhujing Shen, Wei Qian, Kaicheng Li, Xiao Luo, Qingze Zeng, Tao Guo, Hualiang Yu, Yihong Yang, Minming Zhan. Gray matter volumes of insular subregions are not correlated with smoking cessation outcomes but negatively correlated with nicotine dependence severity in chronic smokers. Neuroscience letters. vol 696. 2019-09-02. PMID:30543846. |
the insula, a cortical region that integrates heterogeneous signals about internal states and contributes to executive functions, has been implicated as an important role in the maintenance of nicotine dependence. |
2019-09-02 |
2023-08-13 |
human |
| Joshua C Gray, Michael T Amlung, Max Owens, John Acker, Courtney L Brown, Gene H Brody, Lawrence H Sweet, James MacKillo. The Neuroeconomics of Tobacco Demand: An Initial Investigation of the Neural Correlates of Cigarette Cost-Benefit Decision Making in Male Smokers. Scientific reports. vol 7. 2018-10-24. PMID:28157228. |
collectively, these findings provide initial validation of a cpt fmri paradigm; reveal the interplay of brain regions associated with executive functioning, incentive salience, and interoceptive processing in cigarette decision making; and add to the literature implicating the insula as a key brain region in addiction. |
2018-10-24 |
2023-08-13 |
Not clear |