Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Zifan Zhen, Xueqiang Sun, Shiying Yuan, Jiancheng Zhan. Psychoactive substances for the treatment of neuropsychiatric disorders. Asian journal of psychiatry. vol 101. 2024-09-07. PMID:39243659. |
mdma, influencing multiple neurotransmitter systems including 5-hydroxytryptamine (5-ht), dopamine, and norepinephrine, has been demonstrated to effectively alleviate symptoms of post-traumatic stress disorder, enhancing patients' emotional engagement and resilience during psychotherapy. |
2024-09-07 |
2024-09-10 |
Not clear |
Sarah Mondoloni, Patricia Molina, Salvatore Lecca, Cheng-Hsi Wu, Léo Michel, Denys Osypenko, Fanchon Cachin, Meghan Flanigan, Mauro Congiu, Arnaud L Lalive, Thomas Kash, Fei Deng, Yulong Li, Manuel Mamel. Serotonin release in the habenula during emotional contagion promotes resilience. Science (New York, N.Y.). vol 385. issue 6713. 2024-09-05. PMID:39236168. |
these findings reveal that 5-ht supports vicarious emotions and leads to resilience by tuning definite patterns of habenular neuronal activity. |
2024-09-05 |
2024-09-08 |
mouse |
Andreas Hahn, Murray B Reed, Matej Murgaš, Chrysoula Vraka, Sebastian Klug, Clemens Schmidt, Godber M Godbersen, Benjamin Eggerstorfer, David Gomola, Leo R Silberbauer, Lukas Nics, Cécile Philippe, Marcus Hacker, Rupert Lanzenberge. Dynamics of human serotonin synthesis differentially link to reward anticipation and feedback. Molecular psychiatry. 2024-08-23. PMID:39179904. |
serotonin (5-ht) plays an essential role in reward processing, however, the possibilities to investigate 5-ht action in humans during emotional stimulation are particularly limited. |
2024-08-23 |
2024-08-27 |
human |
Christina A Michel, Noam Schneck, J John Mann, Kevin N Ochsner, Beth S Brodsky, Barbara Stanle. Prefrontal cortex engagement during an fMRI task of emotion regulation as a potential predictor of treatment response in borderline personality disorder. Journal of affective disorders. 2024-08-14. PMID:39142579. |
this study examines how baseline regional brain blood oxygen level dependent (bold) activation during a functional magnetic resonance imaging (fmri) task of emotion regulation is related to treatment response following a six-month randomized clinical trial of dialectical behavior therapy (dbt) or selective serotonin reuptake inhibitor (ssri) treatment. |
2024-08-14 |
2024-08-17 |
Not clear |
Michael J Colwell, Hosana Tagomori, Fei Shang, Hoi Iao Cheng, Chloe E Wigg, Michael Browning, Philip J Cowen, Susannah E Murphy, Catherine J Harme. Direct serotonin release in humans shapes aversive learning and inhibition. Nature communications. vol 15. issue 1. 2024-08-09. PMID:39122687. |
furthermore, increasing synaptic serotonin enhances behavioural inhibition, and shifts bias towards impulse control during exposure to aversive emotional probes. |
2024-08-09 |
2024-08-13 |
human |
Michael Cronquist Christensen, Francesca Canellas, Henrik Loft, Ángel L Montej. Effectiveness of Vortioxetine for the Treatment of Emotional Blunting in Patients with Major Depressive Disorder Experiencing Inadequate Response to SSRI/SNRI Monotherapy in Spain: Results from the COMPLETE Study. Neuropsychiatric disease and treatment. vol 20. 2024-08-05. PMID:39100571. |
the multinational, open-label complete study (nct03835715) investigated the effectiveness of vortioxetine in alleviating emotional blunting in patients with major depressive disorder (mdd) experiencing inadequate response and emotional blunting while being treated with a selective serotonin reuptake inhibitor (ssri) or serotonin-noradrenaline reuptake inhibitor (snri). |
2024-08-05 |
2024-08-07 |
Not clear |
Friederike Holze, Matthias E Liechti, Felix Mülle. Pharmacological Properties of Psychedelics with a Special Focus on Potential Harms. Current topics in behavioral neurosciences. 2024-07-30. PMID:39080236. |
via binding to the serotonin (5-ht) 2a receptor, psychedelics exert profound alterations in various mental domains, including sensation, cognition, emotions, and self-perception. |
2024-07-30 |
2024-08-02 |
Not clear |
Jessica T Jacobs, Rafael S Maior, Hannah F Waguespack, Carolina Campos-Rodriguez, Ludise Malkova, Patrick A Forcell. Focal pharmacological manipulation of serotonin signaling in the amygdala does not alter social behavior. Psychopharmacology. 2024-07-17. PMID:39019996. |
serotonin signaling plays critical roles in social and emotional behaviors. |
2024-07-17 |
2024-07-20 |
Not clear |
Ester Orav, Bojana Kokinovic, Heidi Teppola, Mari Siimon, Sari E Lauri, Henrike Hartun. Arginine vasopressin activates serotonergic neurons in the dorsal raphe nucleus during neonatal development in vitro and in vivo. Neuropharmacology. 2024-07-12. PMID:38996832. |
here we tested the effect of avp on the dorsal raphe nucleus (drn) 5-hydroxytryptamine (5-ht, serotonin) system in male and female neonatal rats, since early 5-ht homeostasis is critical for the development of cortical brain regions and emotional behaviors. |
2024-07-12 |
2024-07-15 |
rat |
Emily T O'Gorman, Gregory J Meye. Developmental cascades from early childhood attachment security to adolescent level of personality functioning among high-risk youth. Development and psychopathology. 2024-06-27. PMID:38934483. |
data from 2,268 children (1165 male; 1103 female) and caregivers participating in future of families and child well-being study (ffcws) were used to examine (1) effects of genetic polymorphisms of the serotonin transporter (5-httlpr) and dopamine d4 receptor (drd4) genes and adverse childhood experiences (aces) on attachment security and emotional and behavioral dysregulation in early childhood and (2) longitudinal associations and transactional relationships among attachment security, dysregulation, negative parenting attitudes and behaviors, social competence, and adolescent personality functioning. |
2024-06-27 |
2024-06-29 |
Not clear |
Guilherme Shigueto Vilar Higa, Felipe José Costa Viana, José Francis-Oliveira, Emily Cruvinel, Thainá Soares Franchin, Tania Marcourakis, Henning Ulrich, Roberto De Pasqual. Serotonergic Neuromodulation of Synaptic Plasticity. Neuropharmacology. 2024-06-14. PMID:38876308. |
through a comparative analysis across three main forebrain structures-the hippocampus, amygdala, and prefrontal cortex, this review discusses the actions of 5-ht on synaptic plasticity, offering insights into its role as a neuromodulator involved in emotional and cognitive functions. |
2024-06-14 |
2024-06-17 |
Not clear |
Xianli Zheng, Li Dingpeng, Xingke Yan, Xiaoqiang Yao, Yongrui Wan. The role and mechanism of 5-HTDRN-BNST neural circuit in anxiety and fear lesions. Frontiers in neuroscience. vol 18. 2024-05-24. PMID:38784088. |
in bnst, corticotropin releasing factor neurons play a role in regulating emotions by reversely regulating excitatory or inhibitory 5-ht neurons. |
2024-05-24 |
2024-05-27 |
Not clear |
Nur Damla Korkmaz, Ugur Cikrikcili, Merve Akan, Emrah Yucesa. Psychedelic therapy in depression and substance use disorders. The European journal of neuroscience. 2024-05-22. PMID:38773750. |
classical psychedelics from n,n'-dimethyltryptamine, psilocybin, mescaline and various lysergamides cause specific alterations in perception, emotion and cognition by acting through serotonin 5-ht |
2024-05-22 |
2024-05-27 |
Not clear |
Wei Zhang, Ying Jin, Fu-Ming Zho. Chronic fluoxetine treatment desensitizes serotoninergic inhibition of GABA inputs and the intrinsic excitability of dorsal raphe serotonin neurons. bioRxiv : the preprint server for biology. 2024-05-20. PMID:38766100. |
dorsal raphe serotonin (5-hydroxytryptamine, 5-ht) neurons are spontaneously active and release 5-ht that is critical to normal brain function such mood and emotion. |
2024-05-20 |
2024-05-27 |
Not clear |
Srikanth Jitte, Saritha Keluth, Priya Bisht, Pranay Wal, Sanjiv Singh, Krishna Murti, Nitesh Kuma. Obesity and Depression: Common Link and Possible Targets. CNS & neurological disorders drug targets. 2024-05-15. PMID:38747226. |
monoamines, including dopamine, serotonin, and norepinephrine, have been widely believed to have a function in emotions and appetite control. |
2024-05-15 |
2024-05-27 |
Not clear |
Alison G P Wakeford, Jonathon A Nye, Elyse L Morin, Jiyoung Mun, Jerrold S Meyer, Mark Goodman, Leonard L Howell, Mar M Sanche. Alterations in adolescent brain serotonin (5HT) Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2024-04-26. PMID:38671147. |
alterations in adolescent brain serotonin (5ht) stress affects brain serotonin (5ht) and dopamine (da) function, and the effectiveness of 5ht and da to regulate stress and emotional responses. |
2024-04-26 |
2024-04-29 |
Not clear |
Maj Vinberg, Roger S McIntyre, Annamaria Giraldi, Klara Coell. Struggling Can Also Show on the Inside: Current Knowledge of the Impact of Childhood Maltreatment on Biomarkers in Mood Disorderss. Neuropsychiatric disease and treatment. vol 20. 2024-03-18. PMID:38496323. |
neurotransmitters, such as serotonin, dopamine, norepinephrine, and hormones (eg the stress hormone cortisol), play a crucial role in regulating mood and emotion. |
2024-03-18 |
2024-03-20 |
Not clear |
Karen K Y Lee, Bidisha Chattopadhyaya, Antônia Samia Fernandes do Nascimento, Luc Moquin, Pedro Rosa-Neto, Bénédicte Amilhon, Graziella Di Crist. Neonatal hypoxia impairs serotonin release and cognitive functions in adult mice. Neurobiology of disease. 2024-03-09. PMID:38460800. |
neurons that release serotonin (5-ht) project to the pfc, and compounds modulating 5-ht activity influence emotion and cognition. |
2024-03-09 |
2024-03-12 |
mouse |
Vibeke Høyrup Dam, Sidsel Høgsgaard Andersen, Sofie Trolle Pedersen, Dea Siggaard Stenbæk, Vibe Gedsoe Frokjae. Serotonin 4 receptor brain binding and oxytocin-promoted affective and social cognition in healthy women - A randomized controlled trial. Comprehensive psychoneuroendocrinology. vol 17. 2024-01-30. PMID:38288372. |
serotonin (5-ht) neurotransmission is also involved in emotional and social behaviors and appear to work in concert with oxytocin. |
2024-01-30 |
2024-02-01 |
Not clear |
Saché M Coury, Vanessa López, Zia Bajwa, Jordan M Garcia, Giana I Teresi, Kate R Kuhlman, Yan Li, Steve Cole, David J Miklowitz, Ioannis Pappas, Tiffany C H. Protocol for teen inflammation glutamate emotion research (TIGER): Toward predictors of treatment response and clinical course in depressed adolescents. Brain, behavior, & immunity - health. vol 35. 2024-01-18. PMID:38235411. |
here, we describe the scientific rationale and protocol for the teen inflammation glutamate emotion research (tiger) study, a prospective 18-month investigation of 160 depressed adolescents who will be assessed before and after treatment with selective serotonin reuptake inhibitors. |
2024-01-18 |
2024-01-20 |
Not clear |