| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Syed Minhaj Rahman, Fatema Esaa, Suephy C Chen, Alice P Pentland, Julie Ryan Wol. ItchyQoL reveals differences in itch symptom experience in routine dermatologic care. Archives of dermatological research. vol 316. issue 7. 2024-06-07. PMID:38847876. |
correlative analyses showed mild itch associated with emotional impacts on qol (p < 0.01), while severe itch associated with functional and emotional impacts on qol (p < 0.01). |
2024-06-07 |
2024-06-10 |
Not clear |
| Syed Minhaj Rahman, Fatema Esaa, Suephy C Chen, Alice P Pentland, Julie Ryan Wol. ItchyQoL reveals differences in itch symptom experience in routine dermatologic care. Archives of dermatological research. vol 316. issue 7. 2024-06-07. PMID:38847876. |
itchyqol demonstrated an emotional impact on qol by mild itch, but a functional and emotional impact on qol by severe itch. |
2024-06-07 |
2024-06-10 |
Not clear |
| Maryam Shayan, Nazgol-Sadat Haddadi, Maryam Shokrian Zeini, Mohadese Shokrian Zeini, Hasti Tashak Golroudbari, Arya Afrooghe, Elham Ahmadi, Asma Rashki, Ahmad-Reza Dehpou. Social interactions and olfactory cues are required for contagious itch in mice. Scientific reports. vol 14. issue 1. 2024-05-17. PMID:38760368. |
in line with these behavioral findings, our study reveals increased activity in brain regions associated with olfaction, emotion, and memory during contagious itch, including the olfactory bulb, the amygdala, the hypothalamus, and the hippocampus, with this activity diminished in anosmic mice. |
2024-05-17 |
2024-05-27 |
mouse |
| Jun-Hui Long, Pu-Jun Wang, Li Xuan, Yao Juan, Guang-Yan Wu, Jun-Fei Teng, Jian-Feng Sui, Ya-Min Li, Liu Yang, Hong-Li Li, Shu-Lei Li. Prelimbic Cortex-Nucleus Accumbens Core Projection Positively Regulates Itch and Itch-Related Aversion. Behavioural brain research. 2024-04-14. PMID:38615978. |
itch is one of the most common clinical symptoms in patients with diseases of the skin, liver, or kidney, and it strongly triggers aversive emotion and scratching behavior. |
2024-04-14 |
2024-04-17 |
rat |
| Jieyan Zheng, Xiao Min Zhang, Wenting Tang, Yonglin Li, Pei Wang, Jianhua Jin, Zhengyi Luo, Shunchang Fang, Shana Yang, Zicheng Wei, Kexin Song, Zihan Huang, Zihao Wang, Ziyu Zhu, Naizhen Shi, Diyun Xiao, Linyu Yuan, Hualin Shen, Lianyan Huang, Boxing L. An insular cortical circuit required for itch sensation and aversion. Current biology : CB. 2024-03-14. PMID:38484733. |
itch encompasses both sensory and emotional dimensions, with the two dimensions reciprocally exacerbating each other. |
2024-03-14 |
2024-03-17 |
Not clear |
| Jieyan Zheng, Xiao Min Zhang, Wenting Tang, Yonglin Li, Pei Wang, Jianhua Jin, Zhengyi Luo, Shunchang Fang, Shana Yang, Zicheng Wei, Kexin Song, Zihan Huang, Zihao Wang, Ziyu Zhu, Naizhen Shi, Diyun Xiao, Linyu Yuan, Hualin Shen, Lianyan Huang, Boxing L. An insular cortical circuit required for itch sensation and aversion. Current biology : CB. 2024-03-14. PMID:38484733. |
the activation of aic elicits aversive emotion and exacerbates pruritogen-induced itch sensation and aversion. |
2024-03-14 |
2024-03-17 |
Not clear |
| Jieyan Zheng, Xiao Min Zhang, Wenting Tang, Yonglin Li, Pei Wang, Jianhua Jin, Zhengyi Luo, Shunchang Fang, Shana Yang, Zicheng Wei, Kexin Song, Zihan Huang, Zihao Wang, Ziyu Zhu, Naizhen Shi, Diyun Xiao, Linyu Yuan, Hualin Shen, Lianyan Huang, Boxing L. An insular cortical circuit required for itch sensation and aversion. Current biology : CB. 2024-03-14. PMID:38484733. |
our study discovers the shared neural circuit (aic → dbnst pathway) underlying the itch sensation and aversion, highlights the critical role of the aic as a central hub for the itch processing, and provides a framework to understand the neural mechanisms underlying the sensation and emotion interaction. |
2024-03-14 |
2024-03-17 |
Not clear |
| Juan Yao, Xuan Li, Guang-Yan Wu, Bing Wu, Jun-Hui Long, Pu-Jun Wang, Shu-Lei Liu, Jie Gao, Jian-Feng Su. The Anterior Insula and its Projection to the Prelimbic Cortex are Involved in the Regulation of 5-HT-Induced Itch. Neuroscience bulletin. 2023-08-08. PMID:37553505. |
these findings provide preliminary evidence that the aic is involved, at least partially via aversive emotion mediation, in the regulation of 5-ht-, but not compound 48/80-induced itch. |
2023-08-08 |
2023-08-16 |
Not clear |
| Hideki Funahashi, Darya Pavlenko, Kent Sakai, Rebecca Verpile, Kristen Sanders, Tasuku Akiyam. Dynorphinergic projections from the central amygdala to the parabrachial nucleus regulate itch. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-07-03. PMID:37399333. |
the amygdala plays a key role in the processing of itch and pain signals as well as emotion. |
2023-07-03 |
2023-08-14 |
mouse |
| Rui Chen, Xiang Xu, Xin-Yue Wang, Wen-Bin Jia, De-Shan Zhao, Na Liu, Zhen Pang, Xiao-Qing Liu, Yan Zhan. The lateral habenula nucleus regulates pruritic sensation and emotion. Molecular brain. vol 16. issue 1. 2023-06-27. PMID:37370111. |
itch is a complex aversive sensory and emotional experience. |
2023-06-27 |
2023-08-14 |
Not clear |
| Jia-Ni Li, Xue-Mei Wu, Liu-Jie Zhao, Han-Xue Sun, Jie Hong, Feng-Ling Wu, Si-Hai Chen, Tao Chen, Hui Li, Yu-Lin Dong, Yun-Qing L. Central medial thalamic nucleus dynamically participates in acute itch sensation and chronic itch-induced anxiety-like behavior in male mice. Nature communications. vol 14. issue 1. 2023-05-03. PMID:37137899. |
itch is an annoying sensation consisting of both sensory and emotional components. |
2023-05-03 |
2023-08-14 |
mouse |
| Guang-Yan Wu, Xiao-Xia Zheng, Shan-Lan Zhao, Yi Wang, Shan Jiang, Yi-Song Wang, Yi-Lun Yi, Juan Yao, Hui-Zhong Wen, Ju Liu, Hong-Li Li, Jian-Feng Su. The prelimbic cortex regulates itch processing by controlling attentional bias. iScience. vol 26. issue 1. 2023-01-09. PMID:36619983. |
recent studies have begun to investigate the neural mechanisms underlying the modulation of sensory and emotional components of itch in the brain. |
2023-01-09 |
2023-08-14 |
Not clear |
| Sheera F Lerman, Michael A Owens, Tony Liu, Joseph Puthumana, C Scott Hultman, Julie A Caffrey, Michael T Smit. Sleep after burn injuries: A systematic review and meta-analysis. Sleep medicine reviews. vol 65. 2022-09-10. PMID:36087455. |
results from the systematic review demonstrate that a variety of sleep disturbances are common in burn survivors, persisting years after the injury and are associated with pain, itch, emotional distress and reduction in quality of life. |
2022-09-10 |
2023-08-14 |
Not clear |
| Mariana Spetea, Helmut Schmidhamme. Kappa Opioid Receptor Ligands and Pharmacology: Diphenethylamines, a Class of Structurally Distinct, Selective Kappa Opioid Ligands. Handbook of experimental pharmacology. vol 271. 2021-11-26. PMID:33454858. |
the endogenous kappa opioid system is expressed in the central and peripheral nervous systems, and has a key role in modulating pain in central and peripheral neuronal circuits and a wide array of physiological functions and neuropsychiatric behaviors (e.g., stress, reward, emotion, motivation, cognition, epileptic seizures, itch, and diuresis). |
2021-11-26 |
2023-08-13 |
human |
| Hideki Mochizuki, Loren Hernandez, Gil Yosipovitch, Norihiro Sadato, Ryusuke Kakig. The Amygdala Network for Processing Itch in Human Brains. Acta dermato-venereologica. vol 100. issue 19. 2021-06-23. PMID:33236767. |
during itch stimuli the amygdala exhibited increased functional connectivity with key brain regions of the serotonergic system responsible for negative emotions (the medial habenula and the median raphe nucleus) and with the memory system, which is responsible for consolidating emotional experiences (the parahippocampus and perirhinal cortex). |
2021-06-23 |
2023-08-13 |
human |
| Takao Setsu, Yusuke Hamada, Daisuke Oikawa, Tomohisa Mori, Yozo Ishiuji, Daisuke Sato, Michiko Narita, Shogo Miyazaki, Eri Furuta, Yukari Suda, Hiroyasu Sakai, Takahiro Ochiya, Hiroyuki Tezuka, Masako Iseki, Eiichi Inada, Akihiro Yamanaka, Naoko Kuzumaki, Minoru Narit. Direct evidence that the brain reward system is involved in the control of scratching behaviors induced by acute and chronic itch. Biochemical and biophysical research communications. vol 534. 2021-04-19. PMID:33220930. |
these findings suggest that repetitive abnormal scratching behaviors under acute and chronic itch stimuli may activate mesolimbic dopamine neurons along with pleasant emotions, while the restriction of such scratching behaviors may initially induce the activation of pvn-crh neurons associated with stress. |
2021-04-19 |
2023-08-13 |
mouse |
| Andrzej Kazimierz Jaworek, Krystyna Szafraniec, Zbigniew Doniec, Magdalena Jaworek, Anna Wojas-Pelc, Mieczysław Pokorsk. Pruritus Characteristics in Severe Atopic Dermatitis in Adult Patients. Advances in experimental medicine and biology. vol 1289. 2021-01-29. PMID:32592153. |
the most significant factors aggravating itch were the following: dry skin (27 patients; 79.4%), exposure to dust mite (22 patients; 64.7%,), and emotional distress (17 patients; 50%). |
2021-01-29 |
2023-08-13 |
human |
| Yozo Ishiuj. Addiction and the itch-scratch cycle. What do they have in common? Experimental dermatology. vol 28. issue 12. 2020-10-28. PMID:31482585. |
itch is a multidimensional experience involving various brain regions associated with sensory perception and emotion, as well as an urge to scratch employing the motor system. |
2020-10-28 |
2023-08-13 |
human |
| Sihan Chen, Xiao-Fei Gao, Yuxi Zhou, Ben-Long Liu, Xian-Yu Liu, Yufen Zhang, Devin M Barry, Kun Liu, Yingfu Jiao, Rita Bardoni, Weifeng Yu, Zhou-Feng Che. A spinal neural circuitry for converting touch to itch sensation. Nature communications. vol 11. issue 1. 2020-10-20. PMID:33033265. |
touch and itch sensations are crucial for evoking defensive and emotional responses, and light tactile touch may induce unpleasant itch sensations (mechanical itch or alloknesis). |
2020-10-20 |
2023-08-13 |
Not clear |
| Sarah E Bache, Edmund Fitzgerald O'Connor, Paul J H Drake, Bruce Philp, Peter Dziewulsk. Development and validation of the Burnt Hand Outcome Tool (BHOT): A patient-led questionnaire for adults with hand burns. Burns : journal of the International Society for Burn Injuries. vol 44. issue 8. 2019-06-10. PMID:30166198. |
measuring the progress of a patient's ability to carry out essential and desired tasks, their emotional state, interaction with society as well as scar, pain and itch as their burn heals, has until now relied on the use of a combination of several different tools. |
2019-06-10 |
2023-08-13 |
Not clear |