| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marco Ritelli, Nicola Chiarelli, Valeria Cinquina, Valeria Bertini, Silvia Piantoni, Alessia Caproli, Silvia Ebe Lucia Della Pinna, Franco Franceschini, Guido Zarattini, Woodrow Gandy, Marina Venturini, Nicoletta Zoppi, Marina Colomb. Bridging the Diagnostic Gap for Hypermobile Ehlers-Danlos Syndrome and Hypermobility Spectrum Disorders: Evidence of a Common Extracellular Matrix Fragmentation Pattern in Patient Plasma as a Potential Biomarker. American journal of medical genetics. Part A. 2024-09-03. PMID:39225014. |
we previously showed extracellular matrix (ecm) disorganization in both heds and hsd dermal fibroblasts involving fibronectin (fn), type i collagen (colli), and tenascin (tn), with matrix metalloproteinase-generated fragments in conditioned media. |
2024-09-03 |
2024-09-05 |
Not clear |
| Shiping He, Shihan Wang, Ruizhou Liu, Hui Chen, Qiang Wang, Dazhou Jia, Longchi Chen, Jihang Dai, Xiaolei L. Conditioned medium of infrapatellar fat stem cells alleviates degradation of chondrocyte extracellular matrix and delays development of osteoarthritis. Gerontology. 2024-08-19. PMID:39159625. |
conditioned medium of infrapatellar fat stem cells alleviates degradation of chondrocyte extracellular matrix and delays development of osteoarthritis. |
2024-08-19 |
2024-08-22 |
human |
| Janet P Raja Xavier, Toshiyuki Okumura, Melina Apweiler, Nirzari A Chacko, Yogesh Singh, Sara Y Brucker, Satoru Takeda, Florian Lang, Madhuri S Salke. Placental growth factor mediates pathological uterine angiogenesis by activating the NFAT5-SGK1 signaling axis in the endometrium: implications for preeclampsia development. Biological research. vol 57. issue 1. 2024-08-17. PMID:39152497. |
in depth characterization of plgf - conditioned medium (cm) from enscs using mass spectrometry and elisa methods revealed low vegf-a and an abundance of extracellular matrix organization associated proteins. |
2024-08-17 |
2024-08-20 |
human |
| Lise Margrethe Sjøgaard-Frich, Morten Sølling Henriksen, Shi Min Lam, Frida Jolande Birkbak, Dominika Czaplinska, Mette Flinck, Stine F Pederse. NHE1 regulation in NAFLD in vitro contributes to hepatocyte injury and HSC crosstalk. The Journal of endocrinology. 2024-08-16. PMID:39150073. |
conditioned medium from pa-treated hepatocytes increased expression of nhe1 and of the fibrosis regulator tissue inhibitor of matrix metalloproteases-2 (timp2) in lx-2 hscs, in a manner abolished by nhe1 ko in hepatocytes. |
2024-08-16 |
2024-08-18 |
Not clear |
| Vasilena E Getova, Erika Pinheiro-Machado, Martin C Harmsen, Janette K Burgess, Alexandra M Smin. The role of extracellular matrix hydrogels and adipose-derived stromal cells in soft tissue vascularization - A systematic review. Biomaterials advances. vol 164. 2024-08-16. PMID:39151272. |
decellularized extracellular matrix (decm) hydrogels loaded with adipose-derived stromal cells (asc) or their conditioned medium (asc cm) present a promising and versatile treatment approach for tissue vascularization and regeneration. |
2024-08-16 |
2024-08-20 |
Not clear |
| Roman E Ushakov, Elena B Burov. Conditioned medium of human mesenchymal stromal/stem cells cultured on decellularized extracellular matrix promotes murine skeletal muscle repair after acute injury. Biochemical and biophysical research communications. vol 736. 2024-08-11. PMID:39128269. |
conditioned medium of human mesenchymal stromal/stem cells cultured on decellularized extracellular matrix promotes murine skeletal muscle repair after acute injury. |
2024-08-11 |
2024-08-14 |
human |
| Roman E Ushakov, Elena B Burov. Conditioned medium of human mesenchymal stromal/stem cells cultured on decellularized extracellular matrix promotes murine skeletal muscle repair after acute injury. Biochemical and biophysical research communications. vol 736. 2024-08-11. PMID:39128269. |
we found recently that conditioned medium from human endometrial mscs cultured on cell-derived decellularized extracellular matrix (cm-decm) is dramatically enriched in a number of paracrine factors such as gm-csf, fgf-2, hgf, mmp-1, mcp-1, il-6, il-8, cxcl-1, -2, -5, -6 (ushakov et al., 2024). |
2024-08-11 |
2024-08-14 |
human |
| Zahra Keshtmand, Behnoosh Khodadadi, Bahare Farzollahi, Samane Eftekhari, Sadjad Khosravimelal, Syed Ataollah Shandiz, Mohammad Tavakkoli Yarak. Engineering of gelatin scaffold by extracellular matrix of Sertoli cells for embryonic stem cell proliferation. Toxicology in vitro : an international journal published in association with BIBRA. 2024-07-19. PMID:39029600. |
in this work, we fabricated electrospun gelatin (eg) mats (i.e., with diameter <500 nm) conditioned with sertoli cells' extracellular matrix (ecm) to simulate both 3d structures and composition of normal testis tissue. |
2024-07-19 |
2024-07-22 |
mouse |
| Xue Bai, Xiang Huang, Jing Yi, Xu Yan, Tingju Hu, Lu Wang, Zijun Wang, Hong Ga. Cardiac Fibroblasts Enhance MMP2 Activity to Suppress Gap Junction Function in Cardiomyocytes. Applied biochemistry and biotechnology. 2024-06-15. PMID:38878160. |
gelatin zymography was performed to detect matrix metalloproteinase (mmp) activity in the conditioned medium. |
2024-06-15 |
2024-06-18 |
rat |
| Siufui Hendrawan, Jennifer Lheman, Ursula Weber, Christian Eugen Oberkofler, Astheria Eryani, René Vonlanthen, Hans Ulrich Bae. Fibroblast matrix implants - a better alternative for incisional hernia repair? Biomedical materials (Bristol, England). 2024-04-11. PMID:38604155. |
the matrix was seeded with fibroblasts (cellularized) and treated with a conditioned
medium (cm) of human umbilical cord mesenchymal stem cells (huc-msc). |
2024-04-11 |
2024-04-14 |
human |
| Qianhao Li, Zhouyuan Yang, Mengli Zhu, Wanli Zhang, Liyile Chen, Hongying Chen, Pengde Kan. Hypobaric hypoxia aggravates osteoarthritis via the alteration of the oxygen environment and bone remodeling in the subchondral zone. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 38. issue 7. 2024-04-04. PMID:38573451. |
furthermore, chondrocytes cultured in a conditioned medium from the hypoxic co-culture model showed decreased anabolism and extracellular matrix compared to those in the normoxic model. |
2024-04-04 |
2024-04-06 |
rat |
| Cassidy M Van Stiphout, Grant Kelly, Nikitha K Pallegar, Eman Elbakry, Ana Valeria Vilchis-Celis, Sherri L Christian, Alicia M Viloria-Peti. Identification of lysyl oxidase as an adipocyte-secreted mediator that promotes a partial mesenchymal-to-epithelial transition in MDA-MB-231 cells. Exploration of targeted anti-tumor therapy. vol 5. issue 1. 2024-03-12. PMID:38468823. |
previous work using a 3-dimensional (3d) co-culture system consisting of tnbc cells, adipocytes and the laminin-rich extracellular matrix (ecm) trademarked as matrigel, demonstrated that adipocytes and adipocyte-derived conditioned media (cm) caused a partial mesenchymal-to-epithelial transition (met). |
2024-03-12 |
2024-03-14 |
Not clear |
| Weiyi Xu, Gregory J Goreczny, Ian Forsythe, Grant Brennan, Theresa Stowell, Katia Brock, Benjamin Capella, Christopher E Turne. Hic-5 regulates extracellular matrix-associated gene expression and cytokine secretion in cancer associated fibroblasts. Experimental cell research. 2024-01-18. PMID:38237846. |
additionally, cytokine array analysis of conditioned media from the hic-5 and hic-5 knockout cancer associated fibroblasts revealed that hic-5 is important for the secretion of several key factors that are associated with matrix remodeling, angiogenesis and immune evasion. |
2024-01-18 |
2024-01-21 |
mouse |
| Haruka Furuta, Yina Sheng, Ayaka Takahashi, Raku Nagano, Naoyuki Kataoka, Claire Marie Perks, Rachel Barker, Fumihiko Hakuno, Shin-Ichiro Takahash. The IGF-Independent Role of IRS-2 in the Secretion of MMP-9 Enhances the Growth of Prostate Carcinoma Cell Line PC3. International journal of molecular sciences. vol 24. issue 20. 2023-10-30. PMID:37894751. |
furthermore, gelatin zymography analysis of the conditioned medium showed that matrix metalloproteinase-9 (mmp-9) was secreted extracellularly in an irs-2 dependent manner when pc3 was cultured under serum starvation conditions. |
2023-10-30 |
2023-11-08 |
human |
| Wai Sun Chan, Xuetang Mo, Philip Pun Ching Ip, Ka Yu Ts. Patient-derived organoid culture in epithelial ovarian cancers-Techniques, applications, and future perspectives. Cancer medicine. 2023-09-30. PMID:37776168. |
patient-derived organoids (pdos) are freshly derived from patients' tissues and are then cultured with extracellular matrix and conditioned medium. |
2023-09-30 |
2023-10-07 |
mouse |
| Catherine S Millar-Haskell, Jason P Gleghor. A Large-format Polyacrylamide Gel with Controllable Matrix Mechanics for Mammalian Cell Culture and Conditioned Media Production. Bio-protocol. vol 13. issue 17. 2023-09-20. PMID:37727869. |
a large-format polyacrylamide gel with controllable matrix mechanics for mammalian cell culture and conditioned media production. |
2023-09-20 |
2023-10-07 |
Not clear |
| Diego Jacho, Parto Babaniamansour, Raquel Osorio, Manuel Toledano, Agustin Rabino, Rafael Garcia-Mata, Eda Yildirim-Aya. Deciphering Cell-specific Effect of Osteoblast-Macrophage Crosstalk in Periodontitis. Tissue engineering. Part A. 2023-08-28. PMID:37639358. |
the results suggested that when macrophages were exposed to osteoblasts-derived conditioned media from the mineralized matrix, the m1 macrophages tended to maintain their pro-inflammatory phenotype. |
2023-08-28 |
2023-09-07 |
Not clear |
| Xinyu Dou, Yunlong Ma, Qipeng Luo, Chunyu Song, Meijuan Liu, Xiao Liu, Donglin Jia, Shuiqing Li, Xiaoguang Li. Therapeutic potential of melatonin in the intervertebral disc degeneration through inhibiting the ferroptosis of nucleus pulpous cells. Journal of cellular and molecular medicine. 2023-06-17. PMID:37329158. |
current studies demonstrated that conditioned medium (cm) from the lipopolysaccharide (lps)-stimulated macrophages caused a series of changes about idd, including increased intracellular oxidative stress (increased reactive oxygen species and malondialdehyde levels, but decreased glutathione levels), upregulated expression of inflammation-associated factors (il-1β, cox-2 and inos), increased expression of key matrix catabolic molecules (mmp-13, adamts4 and adamts5), reduced the expression of major matrix anabolic molecules (col2a1 and acan), and increased ferroptosis (downregulated gpx4 and slc7a11 levels, but upregulated acsl4 and lpcat3 levels) in nucleus pulposus (np) cells. |
2023-06-17 |
2023-08-14 |
Not clear |
| Sepanta Hosseinpour, Huan Dai, Laurence J Walsh, Chun X. Mesoporous Core-Cone Silica Nanoparticles Can Deliver miRNA-26a to Macrophages to Exert Immunomodulatory Effects on Osteogenesis In Vitro. Nanomaterials (Basel, Switzerland). vol 13. issue 11. 2023-06-11. PMID:37299658. |
the conditioned macrophages created a favorable osteoimmune environment for mc3t3-e1 preosteoblasts, driving osteogenic differentiation with enhanced osteogenic marker expression, alkaline phosphatase (alp) production, extracellular matrix formation, and calcium deposition. |
2023-06-11 |
2023-08-14 |
Not clear |
| Rohaina Che Man, Ruszymah Binti Hj Idrus, Wan Izlina Wan Ibrahim, Aminuddin Bin Saim, Yogeswaran Lokanatha. Secretome Analysis of Human Nasal Fibroblast Identifies Proteins That Promote Wound Healing. Advances in experimental medicine and biology. 2023-05-29. PMID:37247133. |
conditioned medium from cultured fibroblast cells is recognized to promote wound healing and growth through the secretion of enzymes, extracellular matrix proteins, and various growth factors and cytokines. |
2023-05-29 |
2023-08-14 |
human |