Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Elizabeth A Lawso. Understanding oxytocin in human physiology and pathophysiology: A path towards therapeutics. Comprehensive psychoneuroendocrinology. vol 19. 2024-07-08. PMID:38974962. |
•oxytocin is a multifaceted hypothalamic-pituitary hormone involved in energy homeostasis, mental health, and bone metabolism.•oxytocin deficiency in energy deficit states and in hypopituitarism is associated with worse mental health and bone health.•oxytocin modulates appetitive neurocircuitry, improves impulse control, and reduces food intake in humans.•defining the oxytocin system in human physiology and pathophysiology could lead to novel therapeutic strategies. |
2024-07-08 |
2024-07-11 |
human |
Stefanie Hardt, Juliana Heidler, Boris Albuquerque, Lucie Valek, Christine Altmann, Annett Wilken-Schmitz, Michael K E Schäfer, Ilka Wittig, Irmgard Tegede. Loss of synaptic zinc transport in progranulin deficient mice may contribute to progranulin-associated psychopathology and chronic pain. Biochimica et biophysica acta. Molecular basis of disease. vol 1863. issue 11. 2018-11-26. PMID:28720486. |
young naïve progranulin deficient mice behaved normal in tests of short-term memory, anxiety, depression and nociception, but after peripheral nerve injury, they showed attention-deficit and depression-like behavior, over-activity, loss of shelter-seeking, reduced impulse control and compulsive feeding behavior, which did not occur in equally injured controls. |
2018-11-26 |
2023-08-13 |
mouse |
Kimberly A Brownley, Christine M Peat, Maria La Via, Cynthia M Buli. Pharmacological approaches to the management of binge eating disorder. Drugs. vol 75. issue 1. 2015-09-14. PMID:25428709. |
to date, the efficacy of various agents that target these and other neurotransmitter systems involved in motivated feeding behavior, mood regulation, and impulse control have been investigated in the treatment of bed. |
2015-09-14 |
2023-08-13 |
human |
Guy A Higgins, Leo B Silenieks, Anne Rossmann, Zoe Rizos, Kevin Noble, Ashlie D Soko, Paul J Fletche. The 5-HT2C receptor agonist lorcaserin reduces nicotine self-administration, discrimination, and reinstatement: relationship to feeding behavior and impulse control. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 5. 2012-07-20. PMID:22189292. |
the 5-ht2c receptor agonist lorcaserin reduces nicotine self-administration, discrimination, and reinstatement: relationship to feeding behavior and impulse control. |
2012-07-20 |
2023-08-12 |
rat |
Walter H Kaye, Ursula F Bailer, Guido K Frank, Angela Wagner, Shannan E Henr. Brain imaging of serotonin after recovery from anorexia and bulimia nervosa. Physiology & behavior. vol 86. issue 1-2. 2005-12-15. PMID:16102788. |
first, 5-ht pathways contribute to the modulation of feeding, mood, and impulse control. |
2005-12-15 |
2023-08-12 |
human |
Walter H Kaye, Guido K Frank, Ursula F Bailer, Shannan E Henr. Neurobiology of anorexia nervosa: clinical implications of alterations of the function of serotonin and other neuronal systems. The International journal of eating disorders. vol 37 Suppl. 2005-08-10. PMID:15852312. |
serotonin neuronal systems, in particular, may create vulnerabilities related to pathological feeding, anxiety and obsessions, and extremes of impulse control, that make individuals susceptible to developing an eating disorder, perhaps in combination with environmental stressors. |
2005-08-10 |
2023-08-12 |
Not clear |
W H Kaye, G K Frank, C C Meltzer, J C Price, C W McConaha, P J Crossan, K L Klump, L Rhode. Altered serotonin 2A receptor activity in women who have recovered from bulimia nervosa. The American journal of psychiatry. vol 158. issue 7. 2001-07-26. PMID:11431241. |
positron emission tomography imaging with [(18)f]altanserin was used to characterize binding of the 5-ht(2a) receptor, which might contribute to altered feeding, mood, or impulse control. |
2001-07-26 |
2023-08-12 |
Not clear |