| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bin Cai, Ting Cai, Zeyu Feng, Huanhuan Zh. The possible anti-tumor actions and mechanisms of active metabolites from Cortex Fraxini. Frontiers in pharmacology. vol 15. 2024-09-30. PMID:39346560. |
modern pharmacological studies have demonstrated that the active metabolites in cortex fraxini, including esculin, esculetin, and fraxetin, exert anti-tumor activities by regulating genes and proteins involved in cancer cell proliferation, apoptosis, invasion, and migration. |
2024-09-30 |
2024-10-02 |
Not clear |
| Liu-Yan Chen, Chuan-Mei Wu, Pan Liang, Jin-Feng Wei, Ting-Ting Lan, Min Guo, Yong-Hua Li, Mei R. [Anti-inflammatory effect and its mechanism of Saracae Cortex based on zebrafish model and network pharmacology]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 11. 2024-07-23. PMID:39041167. |
a lipopolysaccharide(lps)-induced inflammation model of zebrafish was established to evaluate the anti-inflammatory activity of aqueous extract and 70% ethanol extract of saracae cortex with cell apoptosis rate and reactive oxygen species(ros) production rate as indicators. |
2024-07-23 |
2024-07-25 |
zebrafish |
| Liu-Yan Chen, Chuan-Mei Wu, Pan Liang, Jin-Feng Wei, Ting-Ting Lan, Min Guo, Yong-Hua Li, Mei R. [Anti-inflammatory effect and its mechanism of Saracae Cortex based on zebrafish model and network pharmacology]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 11. 2024-07-23. PMID:39041167. |
zebrafish animal experiments showed that saracae cortex could significantly inhibit ros formation and reduce cell apoptosis in juvenile fish caused by inflammation and inhibit the further enhancement of inflammatory response in tissue. |
2024-07-23 |
2024-07-25 |
zebrafish |
| Jiejie Yu, Muyao Wu, Mengying Shi, Yating Gong, Fan Gao, Haiping Gu, Baoqi Dan. Up-regulation of BMAL1 by epigallocatechin-3-gallate improves neurological damage in SBI rats. Brain research bulletin. 2024-07-20. PMID:39032586. |
postoperative administration of egcg up-regulated the content of bmal1 around the cerebral cortex, reduced the oxidative stress level, reduced neuronal apoptosis and the number of degenerated neurons, alleviated cerebral edema, and improved neurological scores in rats. |
2024-07-20 |
2024-07-24 |
rat |
| Shaobin Yang, Xiaoqian Zhao, Yimeng Zhang, Qi Tang, Yanhong Li, Yaqin Du, Peng Y. Tirzepatide shows neuroprotective effects via regulating brain glucose metabolism in APP/PS1 mice. Peptides. 2024-07-13. PMID:39002758. |
app/ps1 mice for 8 weeks with at 10 nmol/kg once-weekly, it significantly decreased the levels of glp-1r, and gfap protein expression and amyloid plaques in the cortex, it also lowered neuronal apoptosis induced by amyloid-β (aβ), but did not affect the anxiety and cognitive function in app/ps1 mice. |
2024-07-13 |
2024-07-16 |
mouse |
| Stephen H Sinclair, Elan Miller, Kiran S Talekar, Stanley S Schwart. Diabetes mellitus associated neurovascular lesions in the retina and brain: A review. Frontiers in ophthalmology. vol 2. 2024-07-10. PMID:38983558. |
specifically, within the retina, and similarly within the brain cortex, lesions occur of the "neurovascular unit", comprised of focal microvascular occlusions, inflammatory endothelial and pericyte injury, with small vessel leakage resulting in injury to astrocytes, müller cells, and microglia, all of which occur with progressive neuronal apoptosis. |
2024-07-10 |
2024-07-12 |
Not clear |
| Masumi Iketani, Mai Hatomi, Yasunori Fujita, Nobuhiro Watanabe, Masafumi Ito, Hideo Kawaguchi, Ikuroh Ohsaw. Inhalation of hydrogen gas mitigates sevoflurane-induced neuronal apoptosis in the neonatal cortex and is associated with changes in protein phosphorylation. Journal of neurochemistry. 2024-06-07. PMID:38849977. |
inhalation of hydrogen gas mitigates sevoflurane-induced neuronal apoptosis in the neonatal cortex and is associated with changes in protein phosphorylation. |
2024-06-07 |
2024-06-10 |
Not clear |
| Rongrong Shen, Zhilin Liu, Li Fei, Yixiang Zhang, Linwu Xu, Chaoqi Xua. REMIMAZOLAM IMPROVES THE MARKERS OF POSTRESUSCITATION CEREBRAL INJURY IN A SWINE MODEL OF CARDIAC ARREST. Shock (Augusta, Ga.). vol 61. issue 5. 2024-04-30. PMID:38517275. |
postresuscitation cerebral injury biomarkers and neurological function were evaluated for a total of 24 h. at 24 h after resuscitation, brain cortex was harvested to evaluate the severity of pathologic damage, including tissue inflammation, oxidative stress, apoptosis, and necroptosis. |
2024-04-30 |
2024-05-02 |
Not clear |
| Gemma Chavarria Ventura, Nadiya Dyshliuk, Oksana Dmytriyeva, Mads Jacob Bagi Nordsten, Maria Mathilde Haugaard, Line Iadsatian Christiansen, Thomas Thymann, Per Torp Sangild, Stanislava Pankratov. Enteral plasma supports brain repair in newborn pigs after birth asphyxia. Brain, behavior, and immunity. 2024-04-27. PMID:38677626. |
plasma supplementation improved gait performance in the beam test, attenuated neuronal apoptosis and affected gene expression related to neuroinflammation, neurotransmission and antioxidants (motor cortex, caudate). |
2024-04-27 |
2024-04-30 |
Not clear |
| Zhiheng Zhang, Wenhan Liu, Meilun Shen, Xiangying Ma, Rouqian Li, Xiaodi Jin, Hui Bai, Li Ga. Correction to: Protective Effect of GM1 Attenuates Hippocampus and Cortex Apoptosis After Ketamine Exposure in Neonatal Rat via PI3K/AKT/GSK3β Pathway. Molecular neurobiology. 2024-04-09. PMID:38592588. |
correction to: protective effect of gm1 attenuates hippocampus and cortex apoptosis after ketamine exposure in neonatal rat via pi3k/akt/gsk3β pathway. |
2024-04-09 |
2024-04-11 |
rat |
| Lujuan Han, Xiaohan Xiang, Yuhui Fu, Sisi Wei, Cong Zhang, Lei Li, Yueping Liu, Huilai Lv, Baoen Shan, Lianmei Zha. Periplcymarin targets glycolysis and mitochondrial oxidative phosphorylation of esophageal squamous cell carcinoma: Implication in anti-cancer therapy. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 128. 2024-03-24. PMID:38522311. |
our previous studies have proved that periplocin (cpp), derived from the extract of cortex periplocae, exhibiting the capacity to hinder proliferation and induce apoptosis in escc cells. |
2024-03-24 |
2024-03-27 |
Not clear |
| Xubo Zhang, Mengqi Liu, Andi Cheng, Bernard Moussian, Jianzhen Zhang, Wei Don. Role of CYP311A1 in wing development of Drosophila melanogaster. Insect science. 2024-03-06. PMID:38445520. |
moreover, the reduction of cyp311a1 function in developing wings does not affect cell proliferation and apoptosis, but entails disordered phalloidin or cadherin distribution, suggesting an abnormal cell morphology and cell cortex structure in wing epithelial cells. |
2024-03-06 |
2024-03-08 |
drosophila_melanogaster |
| Analía G Karadayian, Analia Czerniczyniec, Silvia Lores-Arnai. Apoptosis due to after-effects of acute ethanol exposure in brain cortex: Intrinsic and extrinsic signaling pathways. Neuroscience. 2024-02-29. PMID:38423164. |
apoptosis due to after-effects of acute ethanol exposure in brain cortex: intrinsic and extrinsic signaling pathways. |
2024-02-29 |
2024-03-03 |
mouse |
| Jordana Griebler Luft, Bruno Popik, Débora Aguirre Gonçalves, Fabio Cardoso Cruz, Lucas de Oliveira Alvare. Distinct engrams control fear and extinction memory. Hippocampus. 2024-02-24. PMID:38396226. |
in this study, we utilized the daun02 procedure, which uses c-fos-lacz rats to induce apoptosis of strongly activated neurons and examine whether a new memory trace emerges as a result of a short or long reactivation, or if these processes rely on modifications within the original engram located in the basolateral amygdala (bla) and infralimbic (il) cortex. |
2024-02-24 |
2024-02-26 |
rat |
| Jureeporn U-Pathi, Yen-Chia Yeh, Chia-Wen Chen, Eddy E Owaga, Rong-Hong Hsie. Relationship between Aspartame-Induced Cerebral Cortex Injury and Oxidative Stress, Inflammation, Mitochondrial Dysfunction, and Apoptosis in Sprague Dawley Rats. Antioxidants (Basel, Switzerland). vol 13. issue 1. 2024-01-26. PMID:38275622. |
relationship between aspartame-induced cerebral cortex injury and oxidative stress, inflammation, mitochondrial dysfunction, and apoptosis in sprague dawley rats. |
2024-01-26 |
2024-01-28 |
rat |
| Jureeporn U-Pathi, Yen-Chia Yeh, Chia-Wen Chen, Eddy E Owaga, Rong-Hong Hsie. Relationship between Aspartame-Induced Cerebral Cortex Injury and Oxidative Stress, Inflammation, Mitochondrial Dysfunction, and Apoptosis in Sprague Dawley Rats. Antioxidants (Basel, Switzerland). vol 13. issue 1. 2024-01-26. PMID:38275622. |
the aim of this study was to evaluate the effect of oral aspartame consumption on cerebral cortex injury in the rat brain, and further evaluate the various underlying molecular mechanisms, with a special focus on oxidative stress, inflammation, mitochondrial dysfunction, and apoptosis pathways. |
2024-01-26 |
2024-01-28 |
rat |
| Jiacheng Fang, Peng Jiang, Xincen Wang, Zhongshi Qi, Xin He, Lei Chen, Yurong Guo, Xiaoyun Xu, Run Liu, Duo L. Thinned young apple powder prevents obesity-induced neuronal apoptosis via improving mitochondrial function of cerebral cortex in mice. The Journal of nutritional biochemistry. 2024-01-24. PMID:38266689. |
thinned young apple powder prevents obesity-induced neuronal apoptosis via improving mitochondrial function of cerebral cortex in mice. |
2024-01-24 |
2024-01-27 |
mouse |
| Jiacheng Fang, Peng Jiang, Xincen Wang, Zhongshi Qi, Xin He, Lei Chen, Yurong Guo, Xiaoyun Xu, Run Liu, Duo L. Thinned young apple powder prevents obesity-induced neuronal apoptosis via improving mitochondrial function of cerebral cortex in mice. The Journal of nutritional biochemistry. 2024-01-24. PMID:38266689. |
in summary, yap supplementation suppressed neuronal apoptosis in the cerebral cortex of hfd-induced obesity mice by improving mitochondrial function and inhibiting oxidative stress. |
2024-01-24 |
2024-01-27 |
mouse |
| Xi Zhang, Hong Zheng, Zhitao Ni, Yuyin Shen, Die Wang, Wenqing Li, Liangcai Zhao, Chen Li, Hongchang Ga. Fibroblast growth factor 21 alleviates diabetes-induced cognitive decline. Cerebral cortex (New York, N.Y. : 1991). 2024-01-14. PMID:38220573. |
results revealed that i.c.v fgf21 infusion effectively improved learning and memory performance of dicd mice; neuron loss and apoptosis in hippocampus and cortex were significantly blocked, suggesting a potential neuroprotective role of fgf21 in dicd. |
2024-01-14 |
2024-01-17 |
mouse |
| Lingling He, Chiyu Zhang, Wenjing He, Minjuan X. The emerging role of ectodermal neural cortex 1 in cancer. Scientific reports. vol 14. issue 1. 2024-01-04. PMID:38177640. |
ectodermal neural cortex 1 (enc1) is a protein that plays a crucial role in the regulation of various cellular processes such as cell proliferation, differentiation, and apoptosis. |
2024-01-04 |
2024-01-07 |
Not clear |