| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hasan İlhan, Dilek Kabakcı, Mücahit Seçm. Cytotoxic effects of bee venom-loaded ZIF-8 nanoparticles on thyroid cancer cells: a promising strategy for targeted therapy. Medical oncology (Northwood, London, England). vol 42. issue 1. 2024-12-19. PMID:39699709. |
the effects of these nanoparticles on cell viability, proliferation, and apoptosis were investigated. |
2024-12-19 |
2024-12-21 |
bee |
| Zhenzhong Yan, Lin J. Hck promotes IL-1β-induced extracellular matrix degradation, inflammation, and apoptosis in osteoarthritis via activation of the JAK-STAT3 signaling pathway. Advances in rheumatology (London, England). vol 64. issue 1. 2024-12-19. PMID:39696562. |
in vitro, il-1β-treated human chondrocytes were transfected with hck, and the effects on cell viability, apoptosis, ecm degradation, and jak-stat3 signaling were assessed. |
2024-12-19 |
2024-12-21 |
human |
| Abdolreza Ahmadi, Fatemehsadat Hosseini, Mehdi Rostami, Mohammad Soukhtanlo. Anticancer effects of alpha-lipoic acid, a potent organosulfur compound by modulating matrix metalloproteinases and apoptotic markers in osteosarcoma MG-63 cells. The Journal of steroid biochemistry and molecular biology. 2024-12-18. PMID:39694075. |
the impact of ala on cell cycle progression, apoptosis, migration, and metastasis was analyzed through flow cytometry, scratch assay, and gelatin zymography. |
2024-12-18 |
2024-12-21 |
Not clear |
| Yingmei Li, Jing Ma, Xin Li, Chao Huan. Unveiling Key Genes Modulating Retinal Cell Survival and Autophagy in Glaucoma. Molecular biotechnology. 2024-12-18. PMID:39695008. |
aberrant expression vectors for these genes were transfected into rgcs derived from a glaucoma model to evaluate their impact on cell viability, apoptosis, and autophagy. |
2024-12-18 |
2024-12-21 |
Not clear |
| Xin Luo, Linshan Luo, Rong Lai, Yan Li, Hongyan Zhou, Xiting L. Synthesis and Antioxidant Effects of Edaravone-Loaded MPEG-2000-DSPE Micelles in Rotenone-Induced PC12 Cell Model of Parkinson's Disease. Nanomaterials (Basel, Switzerland). vol 14. issue 23. 2024-12-17. PMID:39683350. |
cytotoxicity assays confirmed that the mde (≤200 ug/ml) exhibited promising cytocompatibility with no significant effect on cell viability, cell cycle regulation, or apoptosis levels. |
2024-12-17 |
2024-12-21 |
Not clear |
| Fatemeh Moosavi, Roya Firoozi, Marjan Tavakkoli, Somayeh Nazari, Alireza Alipour, Omidreza Firuz. Combination of chemotherapy and c-MET inhibitors has synergistic effects in c-MET overexpressing pancreatic cancer cells. Biochimie. 2024-12-15. PMID:39675659. |
the effect of drug combinations on cell cycle and apoptosis induction was examined by rnase/pi flow cytometric assay. |
2024-12-15 |
2024-12-21 |
Not clear |
| Beatrice Bighi, Gregorio Ragazzini, Alessia Gallerani, Andrea Mescola, Chiara Scagliarini, Chiara Zannini, Martina Marcuzzi, Elena Olivi, Claudia Cavallini, Riccardo Tassinari, Michele Bianchi, Lorenzo Corsi, Carlo Ventura, Andrea Alessandrin. Cell stretching devices integrated with live cell imaging: a powerful approach to study how cells react to mechanical cues. Progress in biomedical engineering (Bristol, England). vol 7. issue 1. 2024-12-10. PMID:39655854. |
mechanical stimuli have multiple effects on cell behavior, affecting a number of cellular processes including orientation, proliferation or apoptosis, migration and invasion, the production of extracellular matrix proteins, the activation and translocation of transcription factors, the expression of different genes such as those involved in inflammation and the reprogramming of cell fate. |
2024-12-10 |
2024-12-12 |
Not clear |
| Peter Jung, Stefan P Glaser, Jing Han, Alexandra Popa, Laura Pisarsky, Ningping Feng, Antonia Geyer, Franziska Haderk, Donat Alpar, Christopher Bristow, Susanne Schmittner, Paula-Elena Traexler, Mikhila Mahendra, Birgit Poehn, Poojabahen Gandhi, Roberto Fiorelli, Sanket Awate, Nicole Budano, Florian Martin, Christoph Albrecht, Barbara Drobits-Handl, Sathanandam S Anand, Srinath Kasturirangan, Francesca Trapani, Norbert Schweifer, Joseph R Marszalek, Ulrike Tontsch-Grunt, Mark Pearson, Timothy P Heffernan, Norbert Kraut, Christopher P Vellano, Juan Manuel García-Martíne. A TRAILR2/CDH3 bispecific antibody demonstrates selective apoptosis and tumor regression in CDH3-positive pancreatic cancer. mAbs. vol 16. issue 1. 2024-12-09. PMID:39654063. |
tr2/cdh3 bab is a human bispecific antibody that relies on binding both cdh3 and trailr2 on cell surfaces to achieve trailr2 hyperclustering and efficient apoptosis induction by trailr2 signaling selectively in cdh3-expressing tumor cells. |
2024-12-09 |
2024-12-12 |
human |
| Xinze Liu, Kaijing Sun, Lin Feng, Xin Jin, Ying Sun, Wei Wu, Changbao Chen, Xilin Wa. Review of the Bioactivities and Mechanisms of Fungus Extracts and Compounds in Colon Cancer. Critical reviews in eukaryotic gene expression. vol 35. issue 1. 2024-12-04. PMID:39630035. |
fungi exert significant anticancer effects on cell proliferation, cell cycle arrest, apoptosis, tumor growth, and protein expression. |
2024-12-04 |
2024-12-06 |
human |
| Aya Hiraoka, Yuto Hirata, Yuki Kan, Masato Iwatsuki, Takuji Nakashima, Tooru Ooya, Katsumi Shigemur. Nanaomycin K Inhibited Cell Proliferation and Epithelial-Mesenchymal Transition in Renal Cell Carcinoma. Biological & pharmaceutical bulletin. vol 47. issue 11. 2024-12-01. PMID:39617492. |
we treated the renal cancer cell line achn, caki-1 and renca with nanaomycin k and examined its effects on cell proliferation, apoptosis, and expression of emt and apoptosis markers in vitro and in vivo. |
2024-12-01 |
2024-12-06 |
mouse |
| Cheng Cheng, Jie Li, Dawei Zhang, Dongshuai Xu, Wenyan Y. ITGB1 Alleviates High Glucose-Induced Myocardial Cell Injury by Inhibiting Endoplasmic Reticulum Stress and Cell Apoptosis. International heart journal. vol 65. issue 6. 2024-12-01. PMID:39617503. |
in the rescue experiment conducted using a signaling pathway inhibitor, overexpression of itgb1 could not alleviate the effect of high glucose on cell activity and apoptosis in the presence of an inhibitor. |
2024-12-01 |
2024-12-06 |
Not clear |
| Jumpei Ogura, Koji Yamanoi, Kentaro Ishida, Eijiro Nakamura, Shinji Ito, Naoki Aoyama, Yuki Nakanishi, Toshi Menju, Kosuke Kawaguchi, Yuko Hosoe, Mana Taki, Ryusuke Murakami, Ken Yamaguchi, Junzo Hamanishi, Masaki Manda. A stearate-rich diet and oleate restriction directly inhibit tumor growth via the unfolded protein response. Experimental & molecular medicine. 2024-12-01. PMID:39617788. |
this study analyzed the effects of various fatty acids on cancer cells and revealed that stearic acid, an abundant saturated fatty acid, had a stronger inhibitory effect on cell growth than did palmitic acid, which is also an abundant saturated fatty acid, by inducing dna damage and apoptosis through the unfolded protein response (upr) pathway. |
2024-12-01 |
2024-12-06 |
Not clear |
| Christine Greil, Monika Engelhardt, Julia Felthaus, Ralph Wäsc. Targeting Mitotic Exit in Malignant Cells. Methods in molecular biology (Clifton, N.J.). vol 2874. 2024-11-29. PMID:39614057. |
to study the impact of various antimitotic substances on cell proliferation, especially detect onset of apoptosis depending on different cell cycle phases and thus to identify a possibly entity-dependent mechanism of those agents and their combinations, a combined approach with live-cell imaging and soft-agar colony assays in cultured patient-derived xenografts (pdx) was established. |
2024-11-29 |
2024-12-02 |
Not clear |
| Songhyun Ju, Manish Kumar Singh, Sunhee Han, Jyotsna Ranbhise, Joohun Ha, Wonchae Choe, Kyung-Sik Yoon, Seung Geun Yeo, Sung Soo Kim, Insug Kan. Oxidative Stress and Cancer Therapy: Controlling Cancer Cells Using Reactive Oxygen Species. International journal of molecular sciences. vol 25. issue 22. 2024-11-27. PMID:39596452. |
this review explores the relationship between ros and cancer, focusing on cell death mechanisms like apoptosis, ferroptosis, and autophagy, highlighting the potential therapeutic strategies that exploit ros to target cancer cells. |
2024-11-27 |
2024-11-29 |
Not clear |
| Xiaohua Luo, Xiaopei Guo, Ningning Chen, Rui Peng, Ci Pan, Zhuyin Li, Bing Zhao, Ruonan Ji, Siyu L. miR-155 mediated regulation of PKG1 and its implications on cell invasion, migration, and apoptosis in preeclampsia through NF-κB pathway. Biology direct. vol 19. issue 1. 2024-11-26. PMID:39587640. |
mir-155 mediated regulation of pkg1 and its implications on cell invasion, migration, and apoptosis in preeclampsia through nf-κb pathway. |
2024-11-26 |
2024-11-28 |
Not clear |
| Yimeng Wang, Tingting Li, Guanyu Wang, Chunlei Zhan. VAV1 regulates cell growth in cutaneous T-cell lymphoma via the BAMBI/BMF signalling pathway. European journal of dermatology : EJD. vol 34. issue 5. 2024-11-26. PMID:39589030. |
ctcl cells were also transfected with lentiviral-based vav1 gene knockdown vectors, and the effects of vav1 knockdown on cell proliferation and apoptosis in ctcl cells was determined by mts assay and flow cytometry. |
2024-11-26 |
2024-11-28 |
Not clear |
| Bo Li, Qianhui Zhao, Hanyu Yang, Xueyuying Wang, Zhijun Zhang, Yanling Gong, Xu Wa. Long-Circulating and Targeted Liposomes Co-loading Cisplatin and Mifamurtide: Formulation and Delivery in Osteosarcoma Cells. AAPS PharmSciTech. vol 25. issue 8. 2024-11-26. PMID:39592553. |
in addition to characterization, the cellular uptake, endocytosis pathway and inhibition on cell viability, migration, invasion and cell apoptosis of mg-63 cells were explored. |
2024-11-26 |
2024-11-29 |
Not clear |
| Yingjie Yue, Pingping Chen, Chongwen Re. Piezo1 Modulates Neuronal Autophagy and Apoptosis in Cerebral Ischemia-Reperfusion Injury Through the AMPK-mTOR Signaling Pathway. Neurochemical research. vol 50. issue 1. 2024-11-25. PMID:39585469. |
the effects on cell viability, apoptosis, and autophagy were assessed using cck-8 assays, pi-annexin/v staining combined with flow cytometry, and western blot analysis. |
2024-11-25 |
2024-11-27 |
Not clear |
| Na Liu, Xiao-Ren Zhu, Chang-Ying Wu, Yuan-Yuan Liu, Min-Bin Chen, Jin-Hua G. PCK1 as a target for cancer therapy: from metabolic reprogramming to immune microenvironment remodeling. Cell death discovery. vol 10. issue 1. 2024-11-23. PMID:39578429. |
additionally, pck1 has "nonclassical" nonmetabolic functions, involving the regulation of gene expression, angiogenesis, epigenetic modification, and other processes, and has an impact on cell survival, apoptosis, and other biological activities, as well as the remodeling of the tumor immune microenvironment. |
2024-11-23 |
2024-11-25 |
Not clear |
| Xiaoting Liu, Xilin Dong, YiFan Hu, Cong Dong, Sanzhu Wu, Yanan Fang, Yaxin H. TXN promotes tumorigenesis by activating the ERK1/2 and ERK5 signaling pathways regulating c-Myc in non-small cell lung cancer. Cellular signalling. 2024-11-21. PMID:39571701. |
the effects of knockdown or overexpression txn on cell proliferation, invasion and apoptosis were evaluated by cell counting kit-8, colony formation, wound healing, transwell, tunel staining, and flow cytometric assays. |
2024-11-21 |
2024-11-24 |
Not clear |