Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Mengqi Li, Ting Li, Tingting Jin, Yi Chen, Lan Cheng, Qiheng Liang, Simiao Yan, Tingting Li, Qingzhen Ran, Wanqun Che. Abnormal activation of the Wnt3a/\\xce\\xb2-catenin signaling pathway promotes the expression of T-box transcription factor 3(TBX3) and the epithelial-mesenchymal transition pathway to mediate the occurrence of adenomyosis. Molecular biology reports. 2023-10-25. PMID:37878207. |
t-box transcription factor 3(tbx3) is a transcription factor that can regulate cell proliferation, apoptosis, invasion, and migration in different tumor cells; however, its role in adenomyosis (adm) has not been previously studied. |
2023-10-25 |
2023-11-08 |
Not clear |
Yongjiu Huang, Hongmei Zhu, Xiaohui Ji, Yin Chen, Yanhui Zhang, Ruofei Huang, Jin Xie, Pin Don. TBX3 knockdown suppresses the proliferation of hypopharyngeal carcinoma FaDu cells by inducing G1/S cell cycle arrest and apoptosis. Oncology letters. vol 19. issue 1. 2020-10-01. PMID:31897121. |
tbx3 knockdown suppresses the proliferation of hypopharyngeal carcinoma fadu cells by inducing g1/s cell cycle arrest and apoptosis. |
2020-10-01 |
2023-08-13 |
Not clear |
Meiling Cao, Binlu Zhu, Yuanyuan Sun, Xueqi Zhao, Guangrong Qiu, Weineng Fu, Hongkun Jian. TBX3 deficiency accelerates apoptosis in cardiomyoblasts through regulation of P21 expression. Life sciences. vol 239. 2020-02-13. PMID:31704448. |
in the present study, we found tbx3 knockdown induced proliferation inhibition, cell cycle arrest and apoptosis accompanied by mitochondrial dysfunction in cardiomyoblasts at passage 10 to 15. |
2020-02-13 |
2023-08-13 |
Not clear |
Meiling Cao, Binlu Zhu, Yuanyuan Sun, Xueqi Zhao, Guangrong Qiu, Weineng Fu, Hongkun Jian. TBX3 deficiency accelerates apoptosis in cardiomyoblasts through regulation of P21 expression. Life sciences. vol 239. 2020-02-13. PMID:31704448. |
previous research found that t-box transcription factor 3 (tbx3) was compulsory for the regulation of proliferation, cell cycle arrest and apoptosis in various cells. |
2020-02-13 |
2023-08-13 |
Not clear |
Meiling Cao, Binlu Zhu, Yuanyuan Sun, Xueqi Zhao, Guangrong Qiu, Weineng Fu, Hongkun Jian. TBX3 deficiency accelerates apoptosis in cardiomyoblasts through regulation of P21 expression. Life sciences. vol 239. 2020-02-13. PMID:31704448. |
in conclusion, we demonstrated that tbx3 deficiency accelerated apoptosis via directly regulating p21 expression in senescent cardiomyoblasts. |
2020-02-13 |
2023-08-13 |
Not clear |
Meiling Cao, Binlu Zhu, Yuanyuan Sun, Xueqi Zhao, Guangrong Qiu, Weineng Fu, Hongkun Jian. TBX3 deficiency accelerates apoptosis in cardiomyoblasts through regulation of P21 expression. Life sciences. vol 239. 2020-02-13. PMID:31704448. |
tbx3 deficiency accelerates apoptosis in cardiomyoblasts through regulation of p21 expression. |
2020-02-13 |
2023-08-13 |
Not clear |
Meiling Cao, Binlu Zhu, Yuanyuan Sun, Xueqi Zhao, Guangrong Qiu, Weineng Fu, Hongkun Jian. TBX3 deficiency accelerates apoptosis in cardiomyoblasts through regulation of P21 expression. Life sciences. vol 239. 2020-02-13. PMID:31704448. |
the primary aim of this study was to study the effects of tbx3 on apoptosis in aged cardiomyoblasts and investigate the latent mechanism. |
2020-02-13 |
2023-08-13 |
Not clear |
Tarryn Willmer, Shannagh Hare, Jade Peres, Sharon Princ. The T-box transcription factor TBX3 drives proliferation by direct repression of the p21(WAF1) cyclin-dependent kinase inhibitor. Cell division. vol 11. 2016-04-25. PMID:27110270. |
the cyclin-dependent kinase inhibitor p21(waf1) plays a pivotal role in a myriad of processes including cell cycle arrest, senescence and apoptosis and here we provide a detailed mechanism to show that it is a direct and biologically relevant target of tbx3. |
2016-04-25 |
2023-08-13 |
Not clear |
Lislaine A Wensing, Alexandre H Campo. TBX3, a downstream target of TGF-\\xce\\xb21, inhibits mesangial cell apoptosis. Experimental cell research. vol 328. issue 2. 2015-01-20. PMID:25158279. |
we demonstrated that tbx3 overexpression abrogated mc apoptosis induced by serum deprivation. |
2015-01-20 |
2023-08-13 |
Not clear |
Lislaine A Wensing, Alexandre H Campo. TBX3, a downstream target of TGF-\\xce\\xb21, inhibits mesangial cell apoptosis. Experimental cell research. vol 328. issue 2. 2015-01-20. PMID:25158279. |
tbx3, a downstream target of tgf-\xce\xb21, inhibits mesangial cell apoptosis. |
2015-01-20 |
2023-08-13 |
Not clear |
L Y Tang, L Li, A Borchert, Clara B S Lau, P C Leung, C C Wan. Molecular studies of the congenital malformation induced by Largehead Atractylodes Rhizome, the most commonly used Chinese medicine for threatened miscarriage. Molecular human reproduction. vol 18. issue 12. 2013-05-06. PMID:22907872. |
overexpressions of tbx2 and tbx3 in embryos in vitro rescued lar-induced abnormal limb development and reduced apoptosis in the developing forelimb buds. |
2013-05-06 |
2023-08-12 |
mouse |
Jin-fang Zhang, Ming-liang He, Qi Dong, Wei-dong Xie, Yang-chao Chen, Marie C M Lin, Ping-chung Leung, Ya-ou Zhang, Hsiang-fu Kun. Aqueous extracts of Fructus Ligustri Lucidi enhance the sensitivity of human colorectal carcinoma DLD-1 cells to doxorubicin-induced apoptosis via Tbx3 suppression. Integrative cancer therapies. vol 10. issue 1. 2011-08-04. PMID:20702496. |
therefore, reduction of tbx3 rescued the dysregulated p14(arf)-p53 signaling, which in turn contributed to the sensitivity of dld-1 cells to doxorubicin-induced apoptosis. |
2011-08-04 |
2023-08-12 |
human |
Jin-fang Zhang, Ming-liang He, Qi Dong, Wei-dong Xie, Yang-chao Chen, Marie C M Lin, Ping-chung Leung, Ya-ou Zhang, Hsiang-fu Kun. Aqueous extracts of Fructus Ligustri Lucidi enhance the sensitivity of human colorectal carcinoma DLD-1 cells to doxorubicin-induced apoptosis via Tbx3 suppression. Integrative cancer therapies. vol 10. issue 1. 2011-08-04. PMID:20702496. |
aqueous extracts of fructus ligustri lucidi enhance the sensitivity of human colorectal carcinoma dld-1 cells to doxorubicin-induced apoptosis via tbx3 suppression. |
2011-08-04 |
2023-08-12 |
human |
Natalia Platonova, Maddalena Scotti, Polina Babich, Gloria Bertoli, Elena Mento, Vasco Meneghini, Aliana Egeo, Ileana Zucchi, Giorgio R Merl. TBX3, the gene mutated in ulnar-mammary syndrome, promotes growth of mammary epithelial cells via repression of p19ARF, independently of p53. Cell and tissue research. vol 328. issue 2. 2007-08-10. PMID:17265068. |
however, no effect of tbx3 on cell differentiation or apoptosis has been observed. |
2007-08-10 |
2023-08-12 |
mouse |
Hee Sook Lee, Hyun Hwa Cho, Hoe Kyu Kim, Yong Chan Bae, Hyung Suk Baik, Jin Sup Jun. Tbx3, a transcriptional factor, involves in proliferation and osteogenic differentiation of human adipose stromal cells. Molecular and cellular biochemistry. vol 296. issue 1-2. 2007-07-18. PMID:16955224. |
tbx3 has been reported to be related to apoptosis and proliferation of rat bladder carcinoma cell and to regulate proliferation and differentiation of mouse osteoblast cells. |
2007-07-18 |
2023-08-12 |
mouse |
Claire-Ang\\xc3\\xa9lique Renard, Charlotte Labalette, Carolina Armengol, Delphine Cougot, Yu Wei, Stefano Cairo, Pascal Pineau, Christine Neuveut, Aur\\xc3\\xa9lien de Reyni\\xc3\\xa8s, Anne Dejean, Christine Perret, Marie-Annick Buendi. Tbx3 is a downstream target of the Wnt/beta-catenin pathway and a critical mediator of beta-catenin survival functions in liver cancer. Cancer research. vol 67. issue 3. 2007-03-01. PMID:17283120. |
conversely, ectopic expression of tbx3 inhibits apoptosis induced by beta-catenin depletion. |
2007-03-01 |
2023-08-12 |
mouse |
Claire-Ang\\xc3\\xa9lique Renard, Charlotte Labalette, Carolina Armengol, Delphine Cougot, Yu Wei, Stefano Cairo, Pascal Pineau, Christine Neuveut, Aur\\xc3\\xa9lien de Reyni\\xc3\\xa8s, Anne Dejean, Christine Perret, Marie-Annick Buendi. Tbx3 is a downstream target of the Wnt/beta-catenin pathway and a critical mediator of beta-catenin survival functions in liver cancer. Cancer research. vol 67. issue 3. 2007-03-01. PMID:17283120. |
we further show that inhibition of tbx3 expression by specific sirnas blocks beta-catenin-mediated cell survival and renders cells sensitive to doxorubicin-induced apoptosis. |
2007-03-01 |
2023-08-12 |
mouse |
Aya Ito, Makoto Asamoto, Naomi Hokaiwado, Satoru Takahashi, Tomoyuki Shira. Tbx3 expression is related to apoptosis and cell proliferation in rat bladder both hyperplastic epithelial cells and carcinoma cells. Cancer letters. vol 219. issue 1. 2005-03-31. PMID:15694670. |
immunohistochemical analysis revealed that apoptosis cells are negative and apoptosis resistant cells are positive for tbx3 expression. |
2005-03-31 |
2023-08-12 |
rat |
Aya Ito, Makoto Asamoto, Naomi Hokaiwado, Satoru Takahashi, Tomoyuki Shira. Tbx3 expression is related to apoptosis and cell proliferation in rat bladder both hyperplastic epithelial cells and carcinoma cells. Cancer letters. vol 219. issue 1. 2005-03-31. PMID:15694670. |
these results indicate that tbx3 is a negative regulator of apoptosis in bladder normal epithelial cells and suppression of tbx3 expression causes inhibition of cell proliferation and induction of apoptosis in bc31, a rat bladder carcinoma cells. |
2005-03-31 |
2023-08-12 |
rat |
Aya Ito, Makoto Asamoto, Naomi Hokaiwado, Satoru Takahashi, Tomoyuki Shira. Tbx3 expression is related to apoptosis and cell proliferation in rat bladder both hyperplastic epithelial cells and carcinoma cells. Cancer letters. vol 219. issue 1. 2005-03-31. PMID:15694670. |
tbx3 expression is related to apoptosis and cell proliferation in rat bladder both hyperplastic epithelial cells and carcinoma cells. |
2005-03-31 |
2023-08-12 |
rat |