| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yuheng Hong, Lin Zhang, Weihao Lin, Yannan Yang, Zheng Cao, Xiaoli Feng, Zhentao Yu, Yibo Ga. Transcriptome Sequencing Unveils a Molecular-Stratification-Predicting Prognosis of Sarcoma Associated with Lipid Metabolism. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38338920. |
knockdown of sqle substantially inhibited cell proliferation and colony formation while promoting the apoptosis of sarcoma cells. |
2024-02-10 |
2024-02-12 |
Not clear |
| Changyan Zhu, Xiao Fang, Xiangshen Liu, Chengxi Jiang, Wenjun Ren, Wenmao Huang, Yanyan Jiang, Dong Wan. Squalene monooxygenase facilitates bladder cancer development in part by regulating PCNA. Biochimica et biophysica acta. Molecular cell research. 2024-01-27. PMID:38280406. |
rna-seq data reveals that sqle deficiency leads to dysregulated expression of genes regulating proliferation, migration, and apoptosis. |
2024-01-27 |
2024-01-30 |
Not clear |
| Changyan Zhu, Xiao Fang, Xiangshen Liu, Chengxi Jiang, Wenjun Ren, Wenmao Huang, Yanyan Jiang, Dong Wan. Squalene monooxygenase facilitates bladder cancer development in part by regulating PCNA. Biochimica et biophysica acta. Molecular cell research. 2024-01-27. PMID:38280406. |
knockdown of sqle impairs viability, induces apoptosis, and inhibits the migration and invasion of bc cells. |
2024-01-27 |
2024-01-30 |
Not clear |
| Ruiyuan Xu, Jianlu Song, Rexiati Ruze, Yuan Chen, Xinpeng Yin, Chengcheng Wang, Yupei Zha. SQLE promotes pancreatic cancer growth by attenuating ER stress and activating lipid rafts-regulated Src/PI3K/Akt signaling pathway. Cell death & disease. vol 14. issue 8. 2023-08-04. PMID:37542052. |
our functional experiments demonstrated that sqle facilitated cell proliferation, induced cell cycle progression, and inhibited apoptosis in vitro, while promoting tumor growth in vivo. |
2023-08-04 |
2023-08-14 |
Not clear |
| Liangjian Ma, Wunan Huang, Xiaolei Liang, Guannan Bai, Xiaochen Wang, Hua Jiang, Yang Xin, Lidan Hu, Xiangjun Chen, Chang Li. Inhibition of squalene epoxidase linking with PI3K/AKT signaling pathway suppresses endometrial cancer. Cancer science. 2023-07-13. PMID:37438885. |
in vitro experiments showed that sqle overexpression significantly promoted the proliferation, and inhibited cell apoptosis of ec cells, whereas sqle knockdown or use of terbinafine showed the opposite results. |
2023-07-13 |
2023-08-14 |
mouse |
| Atsushi Kimura, Yo-Han Kim, Kazuyoshi Hashizume, Akira Ito, Katsuyuki Mukai, Keiichiro Kizaki, Shigeru Sat. Effects of oral β-cryptoxanthin administration on the transcriptomes of peripheral neutrophil and liver tissue using microarray analysis in post-weaned Holstein calves. Journal of animal physiology and animal nutrition. 2023-03-06. PMID:36876888. |
adh5 and sqle are involved in the maintenance of cellular homoeostasis by increasing the availability of substrates, and rarres1, cobll1, rtkn, and hes1 are associated with the suppression of apoptosis and carcinogenesis. |
2023-03-06 |
2023-08-14 |
Not clear |
| Haopeng Xiao, Weixuan Chen, George X Tang, Johanna M Smeekens, Ronghu W. Systematic investigation of cellular response and pleiotropic effects in atorvastatin-treated liver cells by MS-based proteomics. Journal of proteome research. vol 14. issue 3. 2016-03-15. PMID:25668447. |
many lipid-related protein abundances were increased in hepg2 cells treated by atorvastatin, including hmgcr, fdft, sqle, and ldlr, while the abundances of proteins involved in cellular response to stress and apoptosis were decreased. |
2016-03-15 |
2023-08-13 |
Not clear |