| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marco Cipolli, Christian Boni, Marianna Penzo, Isabella Villa, Simona Bolamperti, Elena Baldisseri, Annalisa Frattini, Giovanni Porta, Martina Api, Nora Selicato, Pamela Roccia, Daniela Pollutri, Elena Marinelli Busilacchi, Antonella Poloni, Nicole Caporelli, Giovanna D'Amico, Anna Pegoraro, Simone Cesaro, Usua Oyarbide, Antonio Vella, Giuseppe Lippi, Seth J Corey, Roberto Valli, Alessandro Polini, Valentino Bezzerr. Ataluren improves myelopoiesis and neutrophil chemotaxis by restoring ribosome biogenesis and reducing p53 levels in Shwachman-Diamond syndrome cells. British journal of haematology. 2023-10-25. PMID:37876306. |
sds bone marrow haematopoietic progenitors show increased apoptosis and impairment in granulocytic differentiation. |
2023-10-25 |
2023-11-08 |
Not clear |
| Baozhen Qu, Xuemao Liu, Yanjiao Liang, Keke Zheng, Chunling Zhang, Linlin L. Salidroside in the treatment of NAFLD/NASH. Chemistry & biodiversity. 2022-10-09. PMID:36210339. |
it is indicated that sds could improve the status of nafld/nash by ameliorating abnormal\xc2\xa0lipid metabolism, inhibiting oxidative stress, regulating apoptosis and autophagy, reducing\xc2\xa0inflammatory\xc2\xa0response, alleviating\xc2\xa0fibrosis and regulating\xc2\xa0gut microbiota. |
2022-10-09 |
2023-08-14 |
Not clear |
| Zhifu Cui, Ningning Jin, Felix Kwame Amevor, Gang Shu, Xiaxia Du, Xincheng Kang, Zifan Ning, Xun Deng, Yaofu Tian, Qing Zhu, Yan Wang, Diyan Li, Yao Zhang, Xiaoqi Wang, Xue Han, Jing Feng, Xiaoling Zha. Dietary supplementation of salidroside alleviates liver lipid metabolism disorder and inflammatory response to promote hepatocyte regeneration via PI3K/AKT/Gsk3-\\xce\\xb2 pathway. Poultry science. vol 101. issue 9. 2022-08-04. PMID:35926351. |
the results indicated that sds inhibited oa-induced lipid accumulation in chicken primary hepatocytes, increased hepatocyte activity, elevated the mrna expression of proliferation related genes pcna, cdk2, and cyclind1 and increased the protein levels of pcna and cdk2 (p < 0.05), as well as decreased the cleavage levels of caspase-9, caspase-8, and caspase-3 and apoptosis in hepatocytes (p < 0.05). |
2022-08-04 |
2023-08-14 |
chicken |
| Zhifu Cui, Ningning Jin, Felix Kwame Amevor, Gang Shu, Xiaxia Du, Xincheng Kang, Zifan Ning, Xun Deng, Yaofu Tian, Qing Zhu, Yan Wang, Diyan Li, Yao Zhang, Xiaoqi Wang, Xue Han, Jing Feng, Xiaoling Zha. Dietary supplementation of salidroside alleviates liver lipid metabolism disorder and inflammatory response to promote hepatocyte regeneration via PI3K/AKT/Gsk3-\\xce\\xb2 pathway. Poultry science. vol 101. issue 9. 2022-08-04. PMID:35926351. |
in summary, this study showed that 0.3 mg/ml sds attenuated ros generation, inhibited lipid accumulation and hepatocyte apoptosis, and promoted hepatocyte proliferation by targeting the pi3k/akt/gsk3-\xce\xb2 pathway in oa-induced fatty liver model in vitro, and 20 mg/kg sds alleviated high-fat-diet-induced hepatic steatosis, oxidative stress, and inflammatory response in laying hens in vivo. |
2022-08-04 |
2023-08-14 |
chicken |
| Zhifu Cui, Ningning Jin, Felix Kwame Amevor, Gang Shu, Xiaxia Du, Xincheng Kang, Zifan Ning, Xun Deng, Yaofu Tian, Qing Zhu, Yan Wang, Diyan Li, Yao Zhang, Xiaoqi Wang, Xue Han, Jing Feng, Xiaoling Zha. Dietary supplementation of salidroside alleviates liver lipid metabolism disorder and inflammatory response to promote hepatocyte regeneration via PI3K/AKT/Gsk3-\\xce\\xb2 pathway. Poultry science. vol 101. issue 9. 2022-08-04. PMID:35926351. |
salidroside (sds) is an herbal drug which has shown numerous pharmacological activities, such as protecting mitochondrial function, attenuating cell apoptosis and inflammation, and promoting antioxidant defense system. |
2022-08-04 |
2023-08-14 |
chicken |
| Yu Wang, Xueting Mei, Jingquan Yuan, Xiaofang Lai, Donghui X. Taurine zinc solid dispersions enhance bile-incubated L02 cell viability and improve liver function by inhibiting ERK2 and JNK phosphorylation during cholestasis. Toxicology. vol 366-367. 2017-05-12. PMID:27501764. |
therefore, we speculate that taurine zinc sds protect liver function at least in part via a mechanism linked to reduce phosphorylation of jnk and erk2, which suppresses inflammation, apoptosis and cholangiocyte proliferation during cholestasis. |
2017-05-12 |
2023-08-13 |
human |
| A V Sirotkin, M M\\xc3\\xa9sz\\xc3\\xa1rosov\\xc3\\xa1, A H Harrath, R Grossman. Obestatin directly controls chicken ovarian cell functions. Journal of biological regulators and homeostatic agents. vol 30. issue 3. 2017-02-02. PMID:27655483. |
the accumulation of proliferation and apoptosis markers was assessed by immunocytochemistry and sds page-western immunoblotting. |
2017-02-02 |
2023-08-13 |
chicken |
| Thiago C Genaro-Mattos, Patricia P Appolin\\xc3\\xa1rio, Katia C U Mugnol, Carlos Bloch, Iseli L Nantes, Paolo Di Mascio, Sayuri Miyamot. Covalent binding and anchoring of cytochrome c to mitochondrial mimetic membranes promoted by cholesterol carboxyaldehyde. Chemical research in toxicology. vol 26. issue 10. 2014-05-26. PMID:24059586. |
by using sds micelles as a mitochondrial mimetic model, we have demonstrated that chald covalently modifies cytochrome c (cytc), a protein known to participate in electron transport and apoptosis signaling. |
2014-05-26 |
2023-08-12 |
Not clear |
| Alexander V Sirotki. Effect of two types of stress (heat shock/high temperature and malnutrition/serum deprivation) on porcine ovarian cell functions and their response to hormones. The Journal of experimental biology. vol 213. issue Pt 12. 2010-09-01. PMID:20511527. |
the expression of proliferation and apoptosis markers was evaluated by sds page-western blotting whereas radioimmunoassay (ria) measured the release of hormones. |
2010-09-01 |
2023-08-12 |
Not clear |
| Jae Sung Pyo, Si Hun Roh, Dae Ki Kim, Jin Gyun Lee, Yong Yook Lee, Soon Sun Hong, Sung Won Kwon, Jeong Hill Par. Anti-cancer effect of Betulin on a human lung cancer cell line: a pharmacoproteomic approach using 2 D SDS PAGE coupled with nano-HPLC tandem Mass Spectrometry. Planta medica. vol 75. issue 2. 2009-03-30. PMID:19085751. |
in order to identify the molecular players involved in betulin-induced apoptosis, cellular proteins were applied to two-dimensional sodium dodecyl sulfate polyacrylamide gel electrophoresis (2 d sds page) for differential proteomic analysis. |
2009-03-30 |
2023-08-12 |
human |
| Ken-Ichiro Watanabe, Chhaya Ambekar, Hanming Wang, Amanda Ciccolini, Aaron D Schimmer, Yigal Dro. SBDS-deficiency results in specific hypersensitivity to Fas stimulation and accumulation of Fas at the plasma membrane. Apoptosis : an international journal on programmed cell death. vol 14. issue 1. 2009-01-28. PMID:19009351. |
to study the mechanism of fas hypersensitivity, we compared shrna-mediated sbds-knockdown hela cells and sds marrow cd34+ cells for their sensitivity to several groups of apoptosis inducers. |
2009-01-28 |
2023-08-12 |
Not clear |
| A A Olkowski, C Wojnarowicz, S Nain, B Ling, J M Alcorn, B Laarvel. A study on pathogenesis of sudden death syndrome in broiler chickens. Research in veterinary science. vol 85. issue 1. 2008-10-28. PMID:17904171. |
immune staining for caspase-3 confirmed that numerous purkinje cells in the left ventricular myocardium from broiler chickens that died of sds were undergoing apoptosis. |
2008-10-28 |
2023-08-12 |
Not clear |
| Karyn M Austin, Mohan L Gupta, Scott A Coats, Asmin Tulpule, Gustavo Mostoslavsky, Alejandro B Balazs, Richard C Mulligan, George Daley, David Pellman, Akiko Shimamur. Mitotic spindle destabilization and genomic instability in Shwachman-Diamond syndrome. The Journal of clinical investigation. vol 118. issue 4. 2008-05-16. PMID:18324336. |
treatment of primary bmscs and lymphoblasts from sds patients with nocodazole, a microtubule destabilizing agent, led to increased mitotic arrest and apoptosis, consistent with spindle destabilization. |
2008-05-16 |
2023-08-12 |
human |
| Satoko Yui, Tohru Saeki, Ryuhei Kanamoto, Kimikazu Iwam. Characteristics of apoptosis in HCT116 colon cancer cells induced by deoxycholic acid. Journal of biochemistry. vol 138. issue 2. 2005-09-29. PMID:16091589. |
sds and a hydrophilic bile acid, cholic acid, did not induce apoptosis even at cytotoxic concentrations. |
2005-09-29 |
2023-08-12 |
Not clear |
| Y Dror, M H Freedma. Shwachman-Diamond syndrome marrow cells show abnormally increased apoptosis mediated through the Fas pathway. Blood. vol 97. issue 10. 2001-06-14. PMID:11342425. |
in conclusion, sds hematopoietic progenitors are intrinsically flawed and have faulty proliferative properties and increased apoptosis. |
2001-06-14 |
2023-08-12 |
Not clear |
| Y Dror, M H Freedma. Shwachman-Diamond syndrome marrow cells show abnormally increased apoptosis mediated through the Fas pathway. Blood. vol 97. issue 10. 2001-06-14. PMID:11342425. |
bone marrow failure in sds appears mediated by increased apoptosis as the central pathogenetic mechanism. |
2001-06-14 |
2023-08-12 |
Not clear |
| C R Knight, R C Rees, A Platts, T Johnson, M Griffi. Interleukin-2-activated human effector lymphocytes mediate cytotoxicity by inducing apoptosis in human leukaemia and solid tumour target cells. Immunology. vol 79. issue 4. 1993-11-12. PMID:8104887. |
effector cells activated short term (4 hr) with rhil-2 and those mediating rhil-2 lymphokine-activated killer (lak) activity after long-term (4 day) activation were found to induce the formation of sodium dodecyl sulphate (sds)-insoluble apoptotic bodies in nk-sensitive target cells, as well as increasing the level of activity of the apoptosis related enzyme tissue transglutaminase, thus suggesting the induction of the apoptotic pathway as a means of effecting target cell death. |
1993-11-12 |
2023-08-12 |
human |