| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rocío Simón, Ricardo Aparicio, Ben E Housden, Sarah Bray, Ana Busturi. Drosophila p53 controls Notch expression and balances apoptosis and proliferation. Apoptosis : an international journal on programmed cell death. vol 19. issue 10. 2015-05-26. PMID:24858703. |
drosophila p53 controls notch expression and balances apoptosis and proliferation. |
2015-05-26 |
2023-08-13 |
drosophila_melanogaster |
| Xiufeng Liu, Fan Qiu, Zhipeng Liu, Yan Lan, Kai Wang, Ping-Kun Zhou, Yao Wang, Zi-Chun Hu. Urokinase-type plasminogen activator receptor regulates apoptotic sensitivity of colon cancer HCT116 cell line to TRAIL via JNK-p53 pathway. Apoptosis : an international journal on programmed cell death. vol 19. issue 10. 2015-05-26. PMID:25113506. |
the inhibition of p53 by rna interference rescued cells from enhanced apoptosis, thus indicating that p53 is critical for enhancing trail-induced apoptosis. |
2015-05-26 |
2023-08-13 |
human |
| Xiufeng Liu, Fan Qiu, Zhipeng Liu, Yan Lan, Kai Wang, Ping-Kun Zhou, Yao Wang, Zi-Chun Hu. Urokinase-type plasminogen activator receptor regulates apoptotic sensitivity of colon cancer HCT116 cell line to TRAIL via JNK-p53 pathway. Apoptosis : an international journal on programmed cell death. vol 19. issue 10. 2015-05-26. PMID:25113506. |
overall, our results show that upar inhibition can sensitize colon cancer cells hct116 to trail-induced apoptosis via active p53 and mitochondrial apoptotic pathways that jnk inhibition is involved. |
2015-05-26 |
2023-08-13 |
human |
| Jessie Colin, Julie Garibal, Amandine Clavier, Aurore Rincheval-Arnold, Sébastien Gaumer, Bernard Mignotte, Isabelle Guéna. The drosophila Bcl-2 family protein Debcl is targeted to the proteasome by the β-TrCP homologue slimb. Apoptosis : an international journal on programmed cell death. vol 19. issue 10. 2015-05-26. PMID:25208640. |
it inhibits apoptosis by degrading pro-apoptotic regulators, such as caspases or the tumor suppressor p53. |
2015-05-26 |
2023-08-13 |
drosophila_melanogaster |
| Bertrand Mollereau, Dali M. The p53 control of apoptosis and proliferation: lessons from Drosophila. Apoptosis : an international journal on programmed cell death. vol 19. issue 10. 2015-05-26. PMID:25217223. |
the p53 control of apoptosis and proliferation: lessons from drosophila. |
2015-05-26 |
2023-08-13 |
drosophila_melanogaster |
| D V Zosen, M V Glazov. [Role p53 and MAPK signaling integration in the regulation of PC12 cell neural differentiation]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 100. issue 12. 2015-05-26. PMID:25936182. |
p53 is a transcription factor and then induced by cellular stress regulates ageing, cell cycle arrest and apoptosis. |
2015-05-26 |
2023-08-13 |
Not clear |
| Zhushi Li, Kejian Shi, Liying Guan, Qian Jiang, Yang Yang, Caimin X. Activation of p53 by sodium selenite switched human leukemia NB4 cells from autophagy to apoptosis. Oncology research. vol 21. issue 6. 2015-05-22. PMID:25198662. |
activation of p53 by sodium selenite switched human leukemia nb4 cells from autophagy to apoptosis. |
2015-05-22 |
2023-08-13 |
mouse |
| Zhushi Li, Kejian Shi, Liying Guan, Qian Jiang, Yang Yang, Caimin X. Activation of p53 by sodium selenite switched human leukemia NB4 cells from autophagy to apoptosis. Oncology research. vol 21. issue 6. 2015-05-22. PMID:25198662. |
in the present study, we further explored the mechanisms underlying the switch from autophagy to apoptosis and elucidated p53 played a key role. |
2015-05-22 |
2023-08-13 |
mouse |
| Zhushi Li, Kejian Shi, Liying Guan, Qian Jiang, Yang Yang, Caimin X. Activation of p53 by sodium selenite switched human leukemia NB4 cells from autophagy to apoptosis. Oncology research. vol 21. issue 6. 2015-05-22. PMID:25198662. |
furthermore, in p53 mutant u937 leukemia cells, selenite could not elicit such a switch from autophagy to apoptosis, laying emphasis on the crucial role p53 played in this process. |
2015-05-22 |
2023-08-13 |
mouse |
| Anne-Mari Håkelien, Jan Christian Bryne, Kristine G Harstad, Susanne Lorenz, Jonas Paulsen, Jinchang Sun, Tarjei S Mikkelsen, Ola Myklebost, Leonardo A Meza-Zeped. The regulatory landscape of osteogenic differentiation. Stem cells (Dayton, Ohio). vol 32. issue 10. 2015-05-20. PMID:24898411. |
furthermore, we provide a first genome-wide characterization of dna binding sites of the bone master regulatory transcription factor runt-related transcription factor 2 (runx2) in human osteoblasts, revealing target genes associated with regulation of proliferation, migration, apoptosis, and with a significant overlap with p53 regulated genes. |
2015-05-20 |
2023-08-13 |
human |
| Hassan Malekinejad, Nazli Alizadeh-Tabrizi, Araz Ostadi, Johanna Fink-Gremmel. The role of sera from equine grass sickness on apoptosis induction in PC12 Tet-off p53 cell line. Veterinary research forum : an international quarterly journal. vol 6. issue 1. 2015-05-20. PMID:25992246. |
the role of sera from equine grass sickness on apoptosis induction in pc12 tet-off p53 cell line. |
2015-05-20 |
2023-08-13 |
Not clear |
| Seung Woo Lee, Hyun-Kyung Kim, Na-Hyeon Lee, Hee-Yeon Yi, Hong-Sug Kim, Sung Hee Hong, Yong-Kil Hong, Young Ae Jo. The synergistic effect of combination temozolomide and chloroquine treatment is dependent on autophagy formation and p53 status in glioma cells. Cancer letters. vol 360. issue 2. 2015-05-19. PMID:25681668. |
combination treatment of u87 cell (wild type p53) with tmz and cq synergistically reduced cell proliferation and enhanced apoptosis, with increased sub-g1 hypodiploid cells and caspase activation. |
2015-05-19 |
2023-08-13 |
Not clear |
| Seung Woo Lee, Hyun-Kyung Kim, Na-Hyeon Lee, Hee-Yeon Yi, Hong-Sug Kim, Sung Hee Hong, Yong-Kil Hong, Young Ae Jo. The synergistic effect of combination temozolomide and chloroquine treatment is dependent on autophagy formation and p53 status in glioma cells. Cancer letters. vol 360. issue 2. 2015-05-19. PMID:25681668. |
in contrast, combination therapy had no enhanced effect on u373 cell (mutant p53) proliferation and apoptosis within 3 d, although tmz induced autophagy and co-treatment with cq increased autophagic vacuole accumulation. |
2015-05-19 |
2023-08-13 |
Not clear |
| J An, X Zhang, J Qin, Y Wan, Y Hu, T Liu, J Li, W Dong, E Du, C Pan, W Zen. The histone methyltransferase ESET is required for the survival of spermatogonial stem/progenitor cells in mice. Cell death & disease. vol 5. 2015-05-18. PMID:24763053. |
knockdown of eset also upregulated the expression of apoptosis-associated genes (such as p53, caspase9, apaf1), whereas inhibited the expression of apoptosis-suppressing genes (such as bcl2l1, x-linked inhibitor of apoptosis protein). |
2015-05-18 |
2023-08-13 |
mouse |
| M Farhat, A Poissonnier, A Hamze, C Ouk-Martin, J-D Brion, M Alami, J Feuillard, C Jayat-Vignole. Reversion of apoptotic resistance of TP53-mutated Burkitt lymphoma B-cells to spindle poisons by exogenous activation of JNK and p38 MAP kinases. Cell death & disease. vol 5. 2015-05-18. PMID:24787013. |
we found that resistance to spindle poison-induced apoptosis could be reverted in tumor protein p53 (tp53)-mutated cells by ebv (epstein barr virus) infection. |
2015-05-18 |
2023-08-13 |
Not clear |
| Abir Chaabane, Issam M'Sakni, Manel Yahia, Fethi Bougrine, Besma Laabidi, Ramzi Khiari, Samir Ghozzi, Naoufel Berraies, Ammar Bouzian. [Prognostic value of markers of aggressiveness of urinary bladder tumours evaluated by immunohistochemistry]. La Tunisie medicale. vol 92. issue 3. 2015-05-18. PMID:24955967. |
aims: study the expression of the following immunohistochemical markers in tumours of the bladder: proliferating cell nuclear antigen (pcna), ki67 antigen (mib1), the c-erbb2 proto- antigene, the tumor suppressor gene p53, the receptor for epidermal growth factor (egf-r), the apoptosis suppressor gene bcl2, the carcinoembryonic antigen (cea) and epithelial membrane antigen (ema). |
2015-05-18 |
2023-08-13 |
Not clear |
| Dongmin Gu, Shuhong Wang, Isere Kuiatse, Hua Wang, Jin He, Yun Dai, Richard J Jones, Chad C Bjorklund, Jing Yang, Steven Grant, Robert Z Orlowsk. Inhibition of the MDM2 E3 Ligase induces apoptosis and autophagy in wild-type and mutant p53 models of multiple myeloma, and acts synergistically with ABT-737. PloS one. vol 9. issue 9. 2015-05-18. PMID:25181509. |
inhibition of the mdm2 e3 ligase induces apoptosis and autophagy in wild-type and mutant p53 models of multiple myeloma, and acts synergistically with abt-737. |
2015-05-18 |
2023-08-13 |
Not clear |
| Dongmin Gu, Shuhong Wang, Isere Kuiatse, Hua Wang, Jin He, Yun Dai, Richard J Jones, Chad C Bjorklund, Jing Yang, Steven Grant, Robert Z Orlowsk. Inhibition of the MDM2 E3 Ligase induces apoptosis and autophagy in wild-type and mutant p53 models of multiple myeloma, and acts synergistically with ABT-737. PloS one. vol 9. issue 9. 2015-05-18. PMID:25181509. |
a novel inhibitor of this complex, mi-63, was found to induce apoptosis in p53 wild-type myeloma models in association with activation of a p53-mediated cell death program. |
2015-05-18 |
2023-08-13 |
Not clear |
| Dongmin Gu, Shuhong Wang, Isere Kuiatse, Hua Wang, Jin He, Yun Dai, Richard J Jones, Chad C Bjorklund, Jing Yang, Steven Grant, Robert Z Orlowsk. Inhibition of the MDM2 E3 Ligase induces apoptosis and autophagy in wild-type and mutant p53 models of multiple myeloma, and acts synergistically with ABT-737. PloS one. vol 9. issue 9. 2015-05-18. PMID:25181509. |
in mutant p53 models, inhibition of mdm2 with mi-63 also activated apoptosis, albeit at higher concentrations, and this was associated with activation of autophagy. |
2015-05-18 |
2023-08-13 |
Not clear |
| Raushan K Singh, Kyongshin Cho, Satish K R Padi, Junru Yu, Manas Haldar, Tanmay Mandal, Changhui Yan, Gregory Cook, Bin Guo, Sanku Mallik, D K Srivastav. Mechanism of N-Acylthiourea-mediated activation of human histone deacetylase 8 (HDAC8) at molecular and cellular levels. The Journal of biological chemistry. vol 290. issue 10. 2015-05-18. PMID:25605725. |
whereas tm-2-51 selectively induced cell growth inhibition and apoptosis in sh-sy5y cells, it showed no such effects in be(2)-c cells, and this discriminatory feature appears to be encoded in the p53 genotype of the above cells. |
2015-05-18 |
2023-08-13 |
human |