| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tomoko Tadokoro, Asahiro Morishita, Shintaro Fujihara, Hisakazu Iwama, Toshiro Niki, Koji Fujita, Emiko Akashi, Shima Mimura, Kyoko Oura, Teppei Sakamoto, Takako Nomura, Joji Tani, Hisaaki Miyoshi, Hirohito Yoneyama, Takashi Himoto, Mitsuomi Hirashima, Tsutomu Masak. Galectin-9: An anticancer molecule for gallbladder carcinoma. International journal of oncology. vol 48. issue 3. 2016-11-10. PMID:26797414. |
gal-9 induced the apoptosis of gal-9-sensitive gbc cells by increasing the levels of caspase-cleaved keratin 18 and phosphorylated p53. |
2016-11-10 |
2023-08-13 |
human |
| Yiqiong Ma, Qian Yang, Xinghua Chen, Wei Liang, Zhilong Ren, Guohua Din. c-Abl contributes to glucose-promoted apoptosis via p53 signaling pathway in podocytes. Diabetes research and clinical practice. vol 113. 2016-11-10. PMID:26810274. |
c-abl contributes to glucose-promoted apoptosis via p53 signaling pathway in podocytes. |
2016-11-10 |
2023-08-13 |
Not clear |
| Hongling Zhao, Hongbo Wang, Frederick Bauzon, Zhonglei Lu, Hao Fu, Jinhua Cui, Liang Zh. Deletions of Retinoblastoma 1 (Rb1) and Its Repressing Target S Phase Kinase-associated protein 2 (Skp2) Are Synthetic Lethal in Mouse Embryogenesis. The Journal of biological chemistry. vol 291. issue 19. 2016-11-10. PMID:26966181. |
the brain apoptosis was independent of p53 but coincident with proliferation. |
2016-11-10 |
2023-08-13 |
mouse |
| Hongmei Cui, Xingyao Li, Chunhua Han, Qi-En Wang, Hongbo Wang, Han-Fei Ding, Junran Zhang, Chunhong Ya. The Stress-responsive Gene ATF3 Mediates Dichotomous UV Responses by Regulating the Tip60 and p53 Proteins. The Journal of biological chemistry. vol 291. issue 20. 2016-11-10. PMID:26994140. |
as a result, atf3 rather protected the p53 wild-type cells from uv-induced apoptosis. |
2016-11-10 |
2023-08-13 |
Not clear |
| Ricardo E Perez, Hong Shen, Lei Duan, Reuben H Kim, Terresa Kim, No-Hee Park, Carl G Mak. Modeling the Etiology of p53-mutated Cancer Cells. The Journal of biological chemistry. vol 291. issue 19. 2016-11-10. PMID:27022024. |
nutlin-3a occupies the p53-binding site in mdm2 and blocks p53-mdm2 interaction, resulting in the stabilization and activation of p53 and subsequent growth arrest or apoptosis. |
2016-11-10 |
2023-08-13 |
Not clear |
| Jinjin Tong, Dongdong Sun, Chao Yang, Yingxue Wang, Sichao Sun, Qing Li, Jun Bao, Yun Li. Serum starvation and thymidine double blocking achieved efficient cell cycle synchronization and altered the expression of p27, p53, bcl-2 in canine breast cancer cells. Research in veterinary science. vol 105. 2016-11-10. PMID:27033900. |
moreover, the expression of p27, p53 and bcl-2 genes was related to cyclical movements and apoptosis. |
2016-11-10 |
2023-08-13 |
cattle |
| Nithyananda Thorenoor, Petra Faltejskova-Vychytilova, Sonja Hombach, Jitka Mlcochova, Markus Kretz, Marek Svoboda, Ondrej Slab. Long non-coding RNA ZFAS1 interacts with CDK1 and is involved in p53-dependent cell cycle control and apoptosis in colorectal cancer. Oncotarget. vol 7. issue 1. 2016-11-07. PMID:26506418. |
we observed significant increase in p53 levels and parp cleavage in crc cell lines after zfas1 silencing indicating increase in apoptosis. |
2016-11-07 |
2023-08-13 |
Not clear |
| Nithyananda Thorenoor, Petra Faltejskova-Vychytilova, Sonja Hombach, Jitka Mlcochova, Markus Kretz, Marek Svoboda, Ondrej Slab. Long non-coding RNA ZFAS1 interacts with CDK1 and is involved in p53-dependent cell cycle control and apoptosis in colorectal cancer. Oncotarget. vol 7. issue 1. 2016-11-07. PMID:26506418. |
our data suggest that zfas1 may function as oncogene in crc by two main actions: (i) via destabilization of p53 and through (ii) interaction with cdk1/cyclin b1 complex leading to cell cycle progression and inhibition of apoptosis. |
2016-11-07 |
2023-08-13 |
Not clear |
| b' Zsuzs\\xc3\\xa1nna Pap, Izabella \\xc3\\x81gota Ily\\xc3\\xa9s, Simona Liliana Mocan, L\\xc3\\xb3r\\xc3\\xa1nd D\\xc3\\xa9nes, Monica Cristina Muic\\xc4\\x83 Nagy-Bota, Zolt\\xc3\\xa1n P\\xc3\\xa1vai, Annam\\xc3\\xa1ria Sz\\xc3\\xa1nt\\xc3\\xb. Changes in immunoexpression of p53, Ki-67, Ets-1, APAF-1 and PTEN in serrated and conventional colon adenomas. Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. vol 56. issue 4. 2016-11-07. PMID:26743285.' |
according to literature data, proteins like p53, ki-67, apaf-1, ets-1, pten contribute to inhibition of apoptosis and stimulation of proliferation. |
2016-11-07 |
2023-08-13 |
Not clear |
| Mehdi Mirsaeidi, Sanaz Gidfar, Ann Vu, Dean Schraufnage. Annexins family: insights into their functions and potential role in pathogenesis of sarcoidosis. Journal of translational medicine. vol 14. 2016-11-07. PMID:27071553. |
the mechanism of action of annexin a11 may be based upon alterations in delivering calcium to two different apoptosis pathways (caspase and p53). |
2016-11-07 |
2023-08-13 |
Not clear |
| S H Jung, H C Lee, D-M Yu, B C Kim, S M Park, Y-S Lee, H J Park, Y-G Ko, J-S Le. Heparan sulfation is essential for the prevention of cellular senescence. Cell death and differentiation. vol 23. issue 3. 2016-11-01. PMID:26250908. |
thus, blockade of either fgfr1 or akt prohibited p53 and p21 accumulation and cell fate switched from cellular senescence to apoptosis. |
2016-11-01 |
2023-08-13 |
mouse |
| S Fouchécourt, G Livera, S Messiaen, B Fumel, A-S Parent, J-C Marine, P Monge. Apoptosis of Sertoli cells after conditional ablation of murine double minute 2 (Mdm2) gene is p53-dependent and results in male sterility. Cell death and differentiation. vol 23. issue 3. 2016-11-01. PMID:26470726. |
inactivation of mdm2 in scs triggered p53 activation and apoptosis as early as 15.5 days post conception with significant increase in apoptotic scs. |
2016-11-01 |
2023-08-13 |
mouse |
| Eva Martini, Nadine Wittkopf, Claudia Günther, Moritz Leppkes, Hitoshi Okada, Alastair J Watson, Eva Podstawa, Ingo Backert, Kerstin Amann, Markus F Neurath, Christoph Becke. Loss of Survivin in Intestinal Epithelial Progenitor Cells Leads to Mitotic Catastrophe and Breakdown of Gut Immune Homeostasis. Cell reports. vol 14. issue 5. 2016-11-01. PMID:26832409. |
moreover, survivin-deficient animals showed induced phosphorylation of p53 and h2ax and increased levels of cell-intrinsic apoptosis in iecs. |
2016-11-01 |
2023-08-13 |
Not clear |
| Hee-Jin Ahn, Kwang-Soo Kim, Kyung-Won Shin, Kee-Hwan Lim, Jin-Ock Kim, Je-Yong Lee, Jiewan Kim, Ji-Hoon Park, Kyung-Min Yang, Kwang-Hyun Baek, Jeong-Jae Ko, Kyung-Soon Par. Ell3 stabilizes p53 following CDDP treatment via its effects on ubiquitin-dependent and -independent proteasomal degradation pathways in breast cancer cells. Oncotarget. vol 6. issue 42. 2016-10-31. PMID:26540344. |
under conditions of cellular stress, p53 is rapidly stabilized by post-translational modification, thereby escaping degradation and translocating to the nucleus where it activates genes related to cell cycle arrest or apoptosis. |
2016-10-31 |
2023-08-13 |
Not clear |
| Sang-Mi Woo, Youn Kynug Choi, Ah Jeong Kim, Sung-Gook Cho, Seong-Gyu K. p53 causes butein‑mediated apoptosis of chronic myeloid leukemia cells. Molecular medicine reports. vol 13. issue 2. 2016-10-31. PMID:26676515. |
p53 causes butein‑mediated apoptosis of chronic myeloid leukemia cells. |
2016-10-31 |
2023-08-13 |
Not clear |
| Sang-Mi Woo, Youn Kynug Choi, Ah Jeong Kim, Sung-Gook Cho, Seong-Gyu K. p53 causes butein‑mediated apoptosis of chronic myeloid leukemia cells. Molecular medicine reports. vol 13. issue 2. 2016-10-31. PMID:26676515. |
the present study demonstrated that butein-induced apoptosis was mediated by p53. |
2016-10-31 |
2023-08-13 |
Not clear |
| Sang-Mi Woo, Youn Kynug Choi, Ah Jeong Kim, Sung-Gook Cho, Seong-Gyu K. p53 causes butein‑mediated apoptosis of chronic myeloid leukemia cells. Molecular medicine reports. vol 13. issue 2. 2016-10-31. PMID:26676515. |
therefore, the present study suggested that p53 causes the butein-mediated apoptosis of leukemic cells. |
2016-10-31 |
2023-08-13 |
Not clear |
| Zodwa Dlamini, Charleen Rupnarain, Sarala Naicker, Rodney Hull, Zukile Mbit. Expression analysis and association of RBBP6 with apoptosis in colon cancers. Journal of molecular histology. vol 47. issue 2. 2016-10-31. PMID:26905308. |
the novel rbbp6 gene has been implicated in apoptosis due to its ability to bind both p53 and rb, as well as its structural and functional affiliation to ubiquitin and e3 ligases. |
2016-10-31 |
2023-08-13 |
Not clear |
| Khayal Al-Khayal, Maha Abdulla, Omar Al-Obeed, Wael Al Kattan, Ahmad Zubaidi, Mansoor-Ali Vaali-Mohammed, Abdulmalik Alsheikh, Rehan Ahma. Identification of the TP53-induced glycolysis and apoptosis regulator in various stages of colorectal cancer patients. Oncology reports. vol 35. issue 3. 2016-10-28. PMID:26675982. |
the tp53-induced glycolysis and apoptosis regulator (tigar) is a p53 target gene known to regulate glycolysis by acting as fructose bis-phosphatase (fbpase) and modulate reactive oxygen species. |
2016-10-28 |
2023-08-13 |
human |
| Minyue Jiang, Guangpei Chen, Na Lu, Yongjie Zhang, Shulei Jin, Andrew Karaplis, David Goltzman, Dengshun Mia. Deficiency of the parathyroid hormone-related peptide nuclear localization and carboxyl terminal sequences leads to premature skin ageing partially mediated by the upregulation of p27. Experimental dermatology. vol 24. issue 11. 2016-10-27. PMID:26121068. |
compared with wild-type littermates, pthrp ki mice displayed thinner skin and decreased subcutaneous fat and collagen fibres, decreased skin cell proliferation and increased apoptosis, higher expression of p27, p19 and p53 and lower expression of cyclin e and cdk2, and increased reactive oxygen species levels and decreased antioxidant capacity. |
2016-10-27 |
2023-08-13 |
mouse |