| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jun Wang, Rongrong Chen, Xiaojuan Liu, Jianhong Shen, Yaohua Yan, Yilu Gao, Tao Tao, Jiansheng Sh. Hck Promotes Neuronal Apoptosis Following Intracerebral Hemorrhage. Cellular and molecular neurobiology. vol 37. issue 2. 2017-02-23. PMID:27053350. |
in addition, the temporary raise of hck expression was paralleled with the expression of p53, bax, and active caspase-3, suggesting that hck was involved in neuronal apoptosis. |
2017-02-23 |
2023-08-13 |
Not clear |
| Jun Wang, Rongrong Chen, Xiaojuan Liu, Jianhong Shen, Yaohua Yan, Yilu Gao, Tao Tao, Jiansheng Sh. Hck Promotes Neuronal Apoptosis Following Intracerebral Hemorrhage. Cellular and molecular neurobiology. vol 37. issue 2. 2017-02-23. PMID:27053350. |
hence, hck might promote neuronal apoptosis via p53 signaling pathway after ich. |
2017-02-23 |
2023-08-13 |
Not clear |
| Tingting Meng, Jie Wu, Hanxi Yi, Jingwen Liu, Binbin Lu, Ming Yuan, Xuan Huang, Hong Yuan, Fuqiang H. A spermine conjugated stearic acid-g-chitosan oligosaccharide polymer with different types of amino groups for efficient p53 gene therapy. Colloids and surfaces. B, Biointerfaces. vol 145. 2017-02-22. PMID:27289311. |
the therapeutic wild type p53 gene transfected by the sp-csosa polymer restored the function of aberrant p53 gene and induced obvious cell apoptosis and g1 phase arrest. |
2017-02-22 |
2023-08-13 |
Not clear |
| SeJin Kim, Seong Soo A A. Role of p53 isoforms and aggregations in cancer. Medicine. vol 95. issue 26. 2017-02-22. PMID:27368003. |
p53 is a master regulatory protein that is involved in diverse cellular metabolic processes such as apoptosis, dna repair, and cell cycle arrest. |
2017-02-22 |
2023-08-13 |
human |
| Tae Ho Kim, Jae Hyuck Chang, Hee Jin Lee, Jean A Kim, Yeon Soo Lim, Chang Whan Kim, Sok Won Ha. mRNA expression of CDH3, IGF2BP3, and BIRC5 in biliary brush cytology specimens is a useful adjunctive tool of cytology for the diagnosis of malignant biliary stricture. Medicine. vol 95. issue 27. 2017-02-21. PMID:27399126. |
immunohistochemistry for cadherin 3 (cdh3), p53, insulin-like growth factor ii mrna-binding protein 3 (igf2bp3), homeobox b7 (hoxb7), and baculoviral inhibitor of apoptosis repeat containing 5 (birc5) was performed in 4 benign and 4 malignant bile duct tissues. |
2017-02-21 |
2023-08-13 |
Not clear |
| Yanyan Zheng, Li Zhu, Lulu Fan, Wenna Zhao, Jianlong Wang, Xianxiao Hao, Yunhui Zhu, Xiufang Hu, Yaofeng Yuan, Jingwei Shao, Wenfeng Wan. Synthesis, SAR and pharmacological characterization of novel anthraquinone cation compounds as potential anticancer agents. European journal of medicinal chemistry. vol 125. 2017-02-21. PMID:27769031. |
compound 4a-induced apoptosis of a375 cells were showed to be associated with the dissipation of mitochondrial membrane potential (ΔΨm) as a result of the up-regulation of p53 and caspase-3. |
2017-02-21 |
2023-08-13 |
Not clear |
| Wenping Xu, Bo Wang, Mingjun Yang, Yang Zhang, Zhiping Xu, Yun Yang, Haijing Cao, Liming Ta. Tebufenozide induces G1/S cell cycle arrest and apoptosis in human cells. Environmental toxicology and pharmacology. vol 49. 2017-02-21. PMID:27960113. |
in addition, western blotting showed apoptosis was associated with the upregulation of p53, bax and cleaved-parp, as well as downregulation of bcl-2 and parp. |
2017-02-21 |
2023-08-13 |
human |
| Wenping Xu, Bo Wang, Mingjun Yang, Yang Zhang, Zhiping Xu, Yun Yang, Haijing Cao, Liming Ta. Tebufenozide induces G1/S cell cycle arrest and apoptosis in human cells. Environmental toxicology and pharmacology. vol 49. 2017-02-21. PMID:27960113. |
briefly, these results suggest that tebufenozide- induces cell cycle arrest and apoptosis through activating p53 protein in a bax- and bcl-2-triggered mitochondrial pathway. |
2017-02-21 |
2023-08-13 |
human |
| Rui Yamaguchi, Takatoshi Yamamoto, Arisa Sakamoto, Yasuji Ishimaru, Shinji Narahara, Hiroyuki Sugiuchi, Yasuo Yamaguch. A protease-activated receptor 2 agonist (AC-264613) suppresses interferon regulatory factor 5 and decreases interleukin-12p40 production by lipopolysaccharide-stimulated macrophages: Role of p53. Cell biology international. vol 40. issue 6. 2017-02-21. PMID:26833899. |
activation of protease-activated receptor 2 (par-2) upregulates p53 and suppresses apoptosis. |
2017-02-21 |
2023-08-13 |
human |
| Zilong Sun, Wen Zhang, Sujuan Li, Xingchen Xue, Ruiyan Niu, Lei Shi, Baojun Li, Xiaowen Wang, Jundong Wan. Altered miRNAs expression profiling in sperm of mice induced by fluoride. Chemosphere. vol 155. 2017-02-21. PMID:27108368. |
671 predicted target genes against the 16 altered mirnas were mainly involved in protease inhibitor activity, apoptosis, ubiquitin mediated proteolysis, and signaling pathways of calcium, jak-stat, mapk, p53, wnt, which were proved to be directly related to sperm quality. |
2017-02-21 |
2023-08-13 |
mouse |
| Junguo Ma, Yiyi Feng, Yang Liu, Xiaoyu L. PUMA and survivin are involved in the apoptosis of HepG2 cells induced by microcystin-LR via mitochondria-mediated pathway. Chemosphere. vol 157. 2017-02-21. PMID:27235693. |
moreover, we also found that p53 and bax might play an important role in mc-lr-induced apoptosis in hepg2 cells in which puma and survivin were involved. |
2017-02-21 |
2023-08-13 |
human |
| Hongyan Dong, Santokh Gill, Ivan H Curran, Andrew Williams, Byron Kuo, Michael G Wade, Carole L Yau. Toxicogenomic assessment of liver responses following subchronic exposure to furan in Fischer F344 rats. Archives of toxicology. vol 90. issue 6. 2017-02-20. PMID:26194646. |
mir-34a (a p53 target) was the only microrna significantly increased at the 2 mg/kg bw/day, providing evidence to support the importance of apoptosis and cell proliferation in furan hepatotoxicity. |
2017-02-20 |
2023-08-13 |
rat |
| Hongli Hou, Weipeng Xing, Wuyin L. Brahma-related gene 1 induces apoptosis in a p53-dependent manner in human rheumatoid fibroblast-like synoviocyte MH7A. Medicine. vol 95. issue 51. 2017-02-17. PMID:28002318. |
the interaction between brg1 and p53 was assessed by immunoprecipitation (ip).results showed that brg1 overexpression significantly suppressed mh7a cell viability and induced apoptosis (p < 0.01), and its knockdown had opposite effects. |
2017-02-17 |
2023-08-13 |
human |
| Hongli Hou, Weipeng Xing, Wuyin L. Brahma-related gene 1 induces apoptosis in a p53-dependent manner in human rheumatoid fibroblast-like synoviocyte MH7A. Medicine. vol 95. issue 51. 2017-02-17. PMID:28002318. |
however, the regulation on these factors was abrogated by p53 knockdown (p < 0.01).these findings suggest that brg1 may induce apoptosis and suppress inflammation in mh7a cells. |
2017-02-17 |
2023-08-13 |
human |
| Kaushik Banerjee, Satyajit Das, Saikat Majumder, Subrata Majumdar, Jaydip Biswas, Soumitra Kumar Choudhur. Modulation of cell death in human colorectal and breast cancer cells through a manganese chelate by involving GSH with intracellular p53 status. Molecular and cellular biochemistry. vol 427. issue 1-2. 2017-02-17. PMID:28012015. |
herein, we tried to decipher the underlying mechanism of the action of mn-n-(2-hydroxyacetophenone) glycinate (mnng) against differential p53 status bearing hct116, mcf-7, and mda-mb-468 cells on the backdrop of intracellular gsh level and reveal the role of p53 status in modulating gsh-dependant abrogation of mnng-induced apoptosis in these cancer cells. |
2017-02-17 |
2023-08-13 |
human |
| Kaushik Banerjee, Satyajit Das, Saikat Majumder, Subrata Majumdar, Jaydip Biswas, Soumitra Kumar Choudhur. Modulation of cell death in human colorectal and breast cancer cells through a manganese chelate by involving GSH with intracellular p53 status. Molecular and cellular biochemistry. vol 427. issue 1-2. 2017-02-17. PMID:28012015. |
thus p53 status with intracellular gsh is critical for the modulation of mnng-induced apoptosis. |
2017-02-17 |
2023-08-13 |
human |
| Shengming Sun, Zhimin Gu, Hongtuo Fu, Jian Zhu, Xianping Ge, Fujun Xua. Molecular cloning, characterization, and expression analysis of p53 from the oriental river prawn, Macrobrachium nipponense, in response to hypoxia. Fish & shellfish immunology. vol 54. 2017-02-17. PMID:27044329. |
once p53 is activated by a variety of cellular stresses, it transactivates downstream target genes and regulates the cell cycle and apoptosis. |
2017-02-17 |
2023-08-13 |
Not clear |
| Stefanie Santos, Amélia M Silva, Manuela Matos, Sandra M Monteiro, Ana R Álvar. Copper induced apoptosis in Caco-2 and Hep-G2 cells: Expression of caspases 3, 8 and 9, AIF and p53. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. vol 185-186. 2017-02-17. PMID:27046389. |
copper induced apoptosis in caco-2 and hep-g2 cells: expression of caspases 3, 8 and 9, aif and p53. |
2017-02-17 |
2023-08-13 |
Not clear |
| Stefanie Santos, Amélia M Silva, Manuela Matos, Sandra M Monteiro, Ana R Álvar. Copper induced apoptosis in Caco-2 and Hep-G2 cells: Expression of caspases 3, 8 and 9, AIF and p53. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. vol 185-186. 2017-02-17. PMID:27046389. |
then, considering the different apoptosis pathways, the expression of caspases 3, 8 and 9, apoptosis inducing factor (aif) and p53 genes was analyzed by quantitative real time pcr. |
2017-02-17 |
2023-08-13 |
Not clear |
| Daiying Zuo, Zhenfang Duan, Yuanyuan Jia, Tianxue Chu, Qiong He, Juan Yuan, Wei Dai, Zengqiang Li, Liguo Xing, Yingliang W. Amphipathic silica nanoparticles induce cytotoxicity through oxidative stress mediated and p53 dependent apoptosis pathway in human liver cell line HL-7702 and rat liver cell line BRL-3A. Colloids and surfaces. B, Biointerfaces. vol 145. 2017-02-17. PMID:27187187. |
amphipathic silica nanoparticles induce cytotoxicity through oxidative stress mediated and p53 dependent apoptosis pathway in human liver cell line hl-7702 and rat liver cell line brl-3a. |
2017-02-17 |
2023-08-13 |
human |