| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K S Nathiga Nambi, S Abdul Majeed, G Taju, Sridhar Sivasubbu, V Sarath Babu, A S Sahul Hamee. Effects of nicotine on zebrafish: A comparative response between a newly established gill cell line and whole gills. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. vol 195. 2017-03-30. PMID:28257922. |
in addition, the production of ros and the resulting oxidative stress resulted in increased expression of apoptosis related genes p53 and cas3.collectively, our result suggests that nicotine has the potential to induce reactive oxygen species (ros) production, oxidative stress and apoptosis in drg cell line and zebrafish. |
2017-03-30 |
2023-08-13 |
cat |
| Ga Bin Park, Sang Hyun Park, Daejin Kim, Yeong Seok Kim, Sung Ho Yoon, Dae Young Hu. Berberine induces mitochondrial apoptosis of EBV-transformed B cells through p53-mediated regulation of XAF1 and GADD45α. International journal of oncology. vol 49. issue 1. 2017-03-30. PMID:27121748. |
blocking phosphorylation of p38/jnk mapk and treatment with pft-α, a selective p53 inhibitor, effectively prevented apoptosis and the upregulation of phosphorylated p53, xaf1, and gadd45α. |
2017-03-30 |
2023-08-13 |
Not clear |
| Ga Bin Park, Sang Hyun Park, Daejin Kim, Yeong Seok Kim, Sung Ho Yoon, Dae Young Hu. Berberine induces mitochondrial apoptosis of EBV-transformed B cells through p53-mediated regulation of XAF1 and GADD45α. International journal of oncology. vol 49. issue 1. 2017-03-30. PMID:27121748. |
taken together, our results suggest that ros generation might be a predisposing event in berberine-induced mitochondrial apoptosis in ebv-transformed b cells through the upregulation of xaf1 and gadd45α expression by mapk and functional p53. |
2017-03-30 |
2023-08-13 |
Not clear |
| Dajun Liu, Huiping Shang, Ying Li. Stanniocalcin-1 Protects a Mouse Model from Renal Ischemia-Reperfusion Injury by Affecting ROS-Mediated Multiple Signaling Pathways. International journal of molecular sciences. vol 17. issue 7. 2017-03-29. PMID:27420048. |
furthermore, the levels of stc-1,p53, phosphorylated mitogen-activated protein kinase kinase (p-mekk-1), c-jun n-terminal kinase (p-jnk), extracellular signal-regulated kinase (p-erk), ikb kinase (p-ikk), nuclear factor (nf) κb, apoptosis signal-regulating kinase 1 (ask-1) and caspase-3 changed significantly in kidney cells isolated from a riri model when compared to those isolated from a sham control (p < 0.05). |
2017-03-29 |
2023-08-13 |
mouse |
| Arzu Zeynep Karabay, Asli Koc, Tulin Ozkan, Yalda Hekmatshoar, Asuman Sunguroglu, Fugen Aktan, Zeliha Buyukbingo. Methylsulfonylmethane Induces p53 Independent Apoptosis in HCT-116 Colon Cancer Cells. International journal of molecular sciences. vol 17. issue 7. 2017-03-28. PMID:27428957. |
methylsulfonylmethane induces p53 independent apoptosis in hct-116 colon cancer cells. |
2017-03-28 |
2023-08-13 |
Not clear |
| Arzu Zeynep Karabay, Asli Koc, Tulin Ozkan, Yalda Hekmatshoar, Asuman Sunguroglu, Fugen Aktan, Zeliha Buyukbingo. Methylsulfonylmethane Induces p53 Independent Apoptosis in HCT-116 Colon Cancer Cells. International journal of molecular sciences. vol 17. issue 7. 2017-03-28. PMID:27428957. |
in conclusion, our results show for the first time that msm induces apoptosis in hct-116 colon cancer cells regardless of their p53 status. |
2017-03-28 |
2023-08-13 |
Not clear |
| Arzu Zeynep Karabay, Asli Koc, Tulin Ozkan, Yalda Hekmatshoar, Asuman Sunguroglu, Fugen Aktan, Zeliha Buyukbingo. Methylsulfonylmethane Induces p53 Independent Apoptosis in HCT-116 Colon Cancer Cells. International journal of molecular sciences. vol 17. issue 7. 2017-03-28. PMID:27428957. |
since p53 is defective in >50% of tumors, the ability of msm to induce apoptosis independently of p53 may offer an advantage in anti-tumor therapy. |
2017-03-28 |
2023-08-13 |
Not clear |
| Sayantan Bhattacharyya, Vasanthakumar Sekar, Biswanath Majumder, Debapriya G Mehrotra, Samir Banerjee, Anup K Bhowmick, Neyaz Alam, Gautam K Mandal, Jaydip Biswas, Pradip K Majumder, Nabendu Murm. CDKN2A-p53 mediated antitumor effect of Lupeol in head and neck cancer. Cellular oncology (Dordrecht). vol 40. issue 2. 2017-03-27. PMID:28039610. |
the tumor suppressor protein p53 is known to control cell cycle arrest and apoptosis. |
2017-03-27 |
2023-08-13 |
Not clear |
| Hassan Moghtaderi, Houri Sepehri, Farnoosh Attar. Combination of arabinogalactan and curcumin induces apoptosis in breast cancer cells in vitro and inhibits tumor growth via overexpression of p53 level in vivo. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 88. 2017-03-27. PMID:28152473. |
combination of arabinogalactan and curcumin induces apoptosis in breast cancer cells in vitro and inhibits tumor growth via overexpression of p53 level in vivo. |
2017-03-27 |
2023-08-13 |
human |
| Charng Choon Wong, Siang Hui Lim, Sreenivasa Rao Sagineedu, Nordin Haji Lajis, Johnson Stansla. SRJ09, a promising anticancer drug lead: Elucidation of mechanisms of antiproliferative and apoptogenic effects and assessment of in vivo antitumor efficacy. Pharmacological research. vol 107. 2017-03-27. PMID:26940565. |
induction of apoptosis by srj09 in hct-116 cells which occurred independent of p53 and bcl-2 was inhibited in the presence of caspase 8 inhibitor, implicating the extrinsic apoptotic pathway. |
2017-03-27 |
2023-08-13 |
mouse |
| Cuiping Wu, Jinmei Zhang, Xiangang Cao, Qian Yang, Dequan Xi. Effect of Mir-122 on Human Cholangiocarcinoma Proliferation, Invasion, and Apoptosis Through P53 Expression. Medical science monitor : international medical journal of experimental and clinical research. vol 22. 2017-03-24. PMID:27472451. |
effect of mir-122 on human cholangiocarcinoma proliferation, invasion, and apoptosis through p53 expression. |
2017-03-24 |
2023-08-13 |
human |
| Cuiping Wu, Jinmei Zhang, Xiangang Cao, Qian Yang, Dequan Xi. Effect of Mir-122 on Human Cholangiocarcinoma Proliferation, Invasion, and Apoptosis Through P53 Expression. Medical science monitor : international medical journal of experimental and clinical research. vol 22. 2017-03-24. PMID:27472451. |
p53 is a classic tumor suppressor gene that can induce tumor cell apoptosis through various pathways. |
2017-03-24 |
2023-08-13 |
human |
| Cuiping Wu, Jinmei Zhang, Xiangang Cao, Qian Yang, Dequan Xi. Effect of Mir-122 on Human Cholangiocarcinoma Proliferation, Invasion, and Apoptosis Through P53 Expression. Medical science monitor : international medical journal of experimental and clinical research. vol 22. 2017-03-24. PMID:27472451. |
material and methods mir inhibitor or mimics was transfected to bile duct carcinoma cells to evaluate its function on proliferation, invasion, apoptosis, and p53 expression. |
2017-03-24 |
2023-08-13 |
human |
| Cuiping Wu, Jinmei Zhang, Xiangang Cao, Qian Yang, Dequan Xi. Effect of Mir-122 on Human Cholangiocarcinoma Proliferation, Invasion, and Apoptosis Through P53 Expression. Medical science monitor : international medical journal of experimental and clinical research. vol 22. 2017-03-24. PMID:27472451. |
results mir-122 overexpression reduced cell invasion and migration ability, and inhibited cell apoptosis and p53 expression. |
2017-03-24 |
2023-08-13 |
human |
| Sang Hyun Kim, Sung Il Choi, Kyu Yeoun Won, Sung-Jig Li. Distinctive interrelation of p53 with SCO2, COX, and TIGAR in human gastric cancer. Pathology, research and practice. vol 212. issue 10. 2017-03-23. PMID:27499152. |
p53, widely known as a tumor-suppressing gene, has recently been reported to regulate glucose metabolism in human cancers through the synthesis of cytochrome c oxidase 2 (sco2), cytochrome c oxidase complex (cox), and tp53-induced glycolysis and apoptosis regulator (tigar). |
2017-03-23 |
2023-08-13 |
human |
| Manel Boussabbeh, Intidhar Ben Salem, Faicel Belguesmi, Fadwa Neffati, Mohamed Fadhel Najjar, Salwa Abid-Essefi, Hassen Bach. Crocin protects the liver and kidney from patulin-induced apoptosis in vivo. Environmental science and pollution research international. vol 23. issue 10. 2017-03-23. PMID:26856859. |
the analysis of the protein expression in these organs revealed that pat-induced toxicity promotes the induction of apoptosis via the increase in p53, bax, and cytochrome c and the decrease in bcl2 expressions. |
2017-03-23 |
2023-08-13 |
mouse |
| Chang-Hong Cheng, Sheng-Wei Luo, Chao-Xia Ye, An-Li Wang, Zhi-Xun Gu. Identification, characterization and expression analysis of tumor suppressor protein p53 from pufferfish (Takifugu obscurus) after the Vibrio alginolyticus challenge. Fish & shellfish immunology. vol 59. 2017-03-21. PMID:27815196. |
the tumor suppressor protein p53 plays a critical role in cell cycle, apoptosis and dna repair. |
2017-03-21 |
2023-08-13 |
Not clear |
| Rui-Pei Chen, Zhen-Lun Huang, Li-Xuan Liu, Meng-Qi Xiang, Guo-Ping Li, Jia-Lin Feng, Bin Liu, Ling-Fei W. Involvement of endoplasmic reticulum stress and p53 in lncRNA MEG3-induced human hepatoma HepG2 cell apoptosis. Oncology reports. vol 36. issue 3. 2017-03-17. PMID:27432655. |
involvement of endoplasmic reticulum stress and p53 in lncrna meg3-induced human hepatoma hepg2 cell apoptosis. |
2017-03-17 |
2023-08-13 |
mouse |
| Rui-Pei Chen, Zhen-Lun Huang, Li-Xuan Liu, Meng-Qi Xiang, Guo-Ping Li, Jia-Lin Feng, Bin Liu, Ling-Fei W. Involvement of endoplasmic reticulum stress and p53 in lncRNA MEG3-induced human hepatoma HepG2 cell apoptosis. Oncology reports. vol 36. issue 3. 2017-03-17. PMID:27432655. |
these results indicate that meg3 inhibits cell proliferation and induces apoptosis, partially via the activation of the er stress and p53 pathway, in which nf‑κb signaling is required for p53 activation in er stress. |
2017-03-17 |
2023-08-13 |
mouse |
| Yu-Qing Li, Zoey Cheng, Shun Won. Differential Apoptosis Radiosensitivity of Neural Progenitors in Adult Mouse Hippocampus. International journal of molecular sciences. vol 17. issue 5. 2017-03-16. PMID:27331809. |
there was no evidence of radiation-induced apoptosis in the absence of the trp53 (p53) gene but absence of cdkn1a (p21) did not alter the apoptotic response. |
2017-03-16 |
2023-08-13 |
mouse |