| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Prachi Sharma, David E Stallknecht, Elizabeth W Howert. Epizootic haemorrhagic disease virus induced apoptosis in bovine carotid artery endothelium is p53 independent. Veterinaria italiana. vol 52. issue 3-4. 2017-04-28. PMID:27723048. |
in this study, we investigate the involvement of p53 in the induction of apoptosis in a us isolate of ehdv serotype 2 in cow endothelium. |
2017-04-28 |
2023-08-13 |
cattle |
| Prachi Sharma, David E Stallknecht, Elizabeth W Howert. Epizootic haemorrhagic disease virus induced apoptosis in bovine carotid artery endothelium is p53 independent. Veterinaria italiana. vol 52. issue 3-4. 2017-04-28. PMID:27723048. |
our results indicate that ehdv induces apoptosis through a p53 independent mechanism. |
2017-04-28 |
2023-08-13 |
cattle |
| Scott E Counts, Elliott J Mufso. Regulator of Cell Cycle (RGCC) Expression During the Progression of Alzheimer's Disease. Cell transplantation. vol 26. issue 4. 2017-04-28. PMID:27938491. |
in this regard, the multifunctional protein regulator of cell cycle (rgcc) has been implicated in driving g1/s and g2/m phase transitions through its interactions with cdc/cyclin-dependent kinase 1 (cdk1) and is induced by p53, which mediates apoptosis in neurons. |
2017-04-28 |
2023-08-13 |
human |
| Mingjie Lu, Chen Wang, Jian Wan. Tanshinone I induces human colorectal cancer cell apoptosis: The potential roles of Aurora A-p53 and survivin-mediated signaling pathways. International journal of oncology. vol 49. issue 2. 2017-04-25. PMID:27279458. |
tanshinone i markedly inhibited crc cell growth and induced apoptosis in crc cells with functional p53 protein. |
2017-04-25 |
2023-08-13 |
human |
| Mingjie Lu, Chen Wang, Jian Wan. Tanshinone I induces human colorectal cancer cell apoptosis: The potential roles of Aurora A-p53 and survivin-mediated signaling pathways. International journal of oncology. vol 49. issue 2. 2017-04-25. PMID:27279458. |
in tse cells with wild-type p53, data showed that tanshinone i mediated aurora a inhibition results in p53 upregulation, which is required for cell apoptosis. |
2017-04-25 |
2023-08-13 |
human |
| Mingjie Lu, Chen Wang, Jian Wan. Tanshinone I induces human colorectal cancer cell apoptosis: The potential roles of Aurora A-p53 and survivin-mediated signaling pathways. International journal of oncology. vol 49. issue 2. 2017-04-25. PMID:27279458. |
in crc cells with mutant p53 protein (not able to localize to the nucleus), however, aurora a knockdown failed to induce crc cell apoptosis. |
2017-04-25 |
2023-08-13 |
human |
| Mingjie Lu, Chen Wang, Jian Wan. Tanshinone I induces human colorectal cancer cell apoptosis: The potential roles of Aurora A-p53 and survivin-mediated signaling pathways. International journal of oncology. vol 49. issue 2. 2017-04-25. PMID:27279458. |
these observations were further substantiated by the pivotal role of survivin in tanshinone i mediated apoptosis in crc cells with p53 mutant. |
2017-04-25 |
2023-08-13 |
human |
| Monserrath Felix-Portillo, José A Martínez-Quintana, Marina Arenas-Padilla, Verónica Mata-Haro, Silvia Gómez-Jiménez, Gloria Yepiz-Plascenci. Hypoxia drives apoptosis independently of p53 and metallothionein transcript levels in hemocytes of the whiteleg shrimp Litopenaeus vannamei. Chemosphere. vol 161. 2017-04-24. PMID:27459156. |
hypoxia drives apoptosis independently of p53 and metallothionein transcript levels in hemocytes of the whiteleg shrimp litopenaeus vannamei. |
2017-04-24 |
2023-08-13 |
Not clear |
| Chih-Fu Cheng, Tzu-Ming Pa. Ankaflavin and Monascin Induce Apoptosis in Activated Hepatic Stellate Cells through Suppression of the Akt/NF-κB/p38 Signaling Pathway. Journal of agricultural and food chemistry. vol 64. issue 49. 2017-04-24. PMID:27960292. |
apoptosis and g1 phase arrest (g1 phase percentages: 76.1 ± 2.85% and 79.9 ± 1.80%, respectively, versus control cells 65.9 ± 4.94%; p < 0.05) correlated with increased p53 and p21 levels and caspase 3 activity and decreased cyclin d1 and bcl-2-family protein levels (p < 0.05, all cases). |
2017-04-24 |
2023-08-13 |
Not clear |
| Sheng Huaying, Yao Dong, Zhu Chihong, Qian Xiaoqian, Wan Danying, Feng Jiangu. Transglutaminase 2 Inhibitor KCC009 Induces p53-Independent Radiosensitization in Lung Adenocarcinoma Cells. Medical science monitor : international medical journal of experimental and clinical research. vol 22. 2017-04-24. PMID:28002389. |
background the expression of transglutaminase 2 (tg2) is correlated to dna damage repair and apoptosis through the p53 pathway. |
2017-04-24 |
2023-08-13 |
human |
| Anna Kakehashi, Vasily E Stefanov, Naomi Ishii, Takahiro Okuno, Hideki Fujii, Kazuaki Kawai, Norifumi Kawada, Hideki Wanibuch. Proteome Characteristics of Non-Alcoholic Steatohepatitis Liver Tissue and Associated Hepatocellular Carcinomas. International journal of molecular sciences. vol 18. issue 2. 2017-04-24. PMID:28218651. |
alterations in downstream protein expression pointed to significant activation of transforming growth factor β, smad family member 3, β-catenin, nrf2, srebp-lxrα and nuclear receptor-interacting protein 1 (nrip1), and inhibition of ppars and p53 in human nash biopsies and/or hccs, suggesting their involvement in accumulation of lipids, development of fibrosis, oxidative stress, cell proliferation and suppression of apoptosis in nash hepatocarcinogenesis. |
2017-04-24 |
2023-08-13 |
mouse |
| Lili Chen, Fangling Ji, Yongming Bao, Jing Xia, Lianying Guo, Jingyun Wang, Yachen L. Biocompatible cationic pullulan-g-desoxycholic acid-g-PEI micelles used to co-deliver drug and gene for cancer therapy. Materials science & engineering. C, Materials for biological applications. vol 70. issue Pt 1. 2017-04-21. PMID:27770912. |
more excitedly, in comparison with single dox or p53 delivery, the co-delivery of dox and gene p53 using pdp micelles displayed higher cytotoxicity, induced higher apoptosis rate of tumor cells and blocked more effectively the migration of cancer cells in vitro. |
2017-04-21 |
2023-08-13 |
mouse |
| Qing-Sheng Zhao, Ling-Ling Hu, Zhi-Dong Wang, Zhao-Pei Li, Ai-Wen Wang, Jing Li. Resveratrol-loaded folic acid-grafted dextran stearate submicron particles exhibits enhanced antitumor efficacy in non-small cell lung cancers. Materials science & engineering. C, Materials for biological applications. vol 72. 2017-04-20. PMID:28024576. |
we have found that apoptosis induced by rsv-df was associated with the higher expression of p53, caspase-3, and bax than the free rsv. |
2017-04-20 |
2023-08-13 |
Not clear |
| Václav Brázda, Jan Coufa. Recognition of Local DNA Structures by p53 Protein. International journal of molecular sciences. vol 18. issue 2. 2017-04-20. PMID:28208646. |
p53 plays critical roles in regulating cell cycle, apoptosis, senescence and metabolism and is commonly mutated in human cancer. |
2017-04-20 |
2023-08-13 |
human |
| Chun-Yen Liu, Chang-Hung Hsieh, Seung-Hun Kim, Jing-Ping Wang, Yu-Lin Ni, Chun-Li Su, Ching-Fa Yao, Kang Fan. An indolylquinoline derivative activates DNA damage response and apoptosis in human hepatocellular carcinoma cells. International journal of oncology. vol 49. issue 6. 2017-04-17. PMID:27748837. |
in brief, the study demonstrates that the effectiveness of emmq accentuated apoptosis of hepatocarcinoma cells by activating p53. |
2017-04-17 |
2023-08-13 |
human |
| Xia Zhang, Jingyu Hu, Yan Che. Betulinic acid and the pharmacological effects of tumor suppression (Review). Molecular medicine reports. vol 14. issue 5. 2017-04-17. PMID:27748864. |
the antitumor pharmacological effects of ba consist of triggering apoptosis via the mitochondrial pathway, regulating the cell cycle and the angiogenic pathway via factors, including specificity protein transcription factors, cyclin d1 and epidermal growth factor receptor, inhibiting the signal transducer and activator of transcription 3 and nuclear factor‑κb signaling pathways, preventing the invasion and metastasis of tumor cells, and affecting the expression of topoisomerase i, p53 and lamin b1. |
2017-04-17 |
2023-08-13 |
Not clear |
| Shin Kim, Dong Eun Kim, Taeg Kyu Kwon, Jinho Lee, Jong-Wook Par. The multi-target drug BAI induces apoptosis in various human cancer cells through modulation of Bcl-xL protein. International journal of oncology. vol 49. issue 6. 2017-04-17. PMID:27840907. |
furthermore, bai-induced apoptosis was strongly associated with downregulation of b-cell lymphoma-extra large (bcl-xl), but not bcl-2, and bai modulated the interactions among p53 and bcl-2 family proteins in human cancer cells. |
2017-04-17 |
2023-08-13 |
human |
| Srinivas R Sripathi, Weilue He, O'Donnell Sylvester, Musa Neksumi, Ji-Yeon Um, Thagriki Dluya, Paul S Bernstein, Wan Jin Jahn. Altered Cytoskeleton as a Mitochondrial Decay Signature in the Retinal Pigment Epithelium. The protein journal. vol 35. issue 3. 2017-04-13. PMID:27029380. |
specific cytoskeletal and nuclear protein-binding mechanisms may exist to regulate prohibitin-mediated reactions as key elements, including vimentin and p53, to control apoptosis in mitochondria and the nucleus. |
2017-04-13 |
2023-08-13 |
Not clear |
| Tomoko Sho, Toru Hachisuga, Toshinori Kawagoe, Rie Urabe, Tomoko Kurita, Seiji Kagami, Shohei Shimajiri, Yoshihisa Fujin. Expression of p53 in endometrial polyps with special reference to the p53 signature. Histology and histopathology. vol 31. issue 7. 2017-04-12. PMID:26727623. |
among the premenopausal emps, a multivariate analysis showed the labeling index (li) for ki-67 to correlate significantly with that for p53 (p<0.001), but not that for apoptosis. |
2017-04-12 |
2023-08-13 |
Not clear |
| Shanghui Zhou, Yun Zhu, Mubarak Mashrah, Xinyu Zhang, Zhijing He, Zhigang Yao, Chunye Zhang, Feng Guo, Yongjie Hu, Chenping Zhan. Expression pattern of DKK3, dickkopf WNT signaling pathway inhibitor 3, in the malignant progression of oral submucous fibrosis. Oncology reports. vol 37. issue 2. 2017-04-11. PMID:27959428. |
furthermore, through analysis of its co-expressed genes, ddk3 may deregulate wnt signaling, p53 signaling, apoptosis, ca2+ signaling and mitochondrial signaling pathways in oscc pathogenesis. |
2017-04-11 |
2023-08-13 |
Not clear |