| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Manish K Yadav, Nandini M Manoli, SubbaRao V Madhunapantul. Comparative Assessment of Vitamin-B12, Folic Acid and Homocysteine Levels in Relation to p53 Expression in Megaloblastic Anemia. PloS one. vol 11. issue 10. 2017-06-13. PMID:27780269. |
however, it is not clear whether this apoptosis induction is due to elevated p53 level or due to any other mechanism. |
2017-06-13 |
2023-08-13 |
Not clear |
| Manish K Yadav, Nandini M Manoli, SubbaRao V Madhunapantul. Comparative Assessment of Vitamin-B12, Folic Acid and Homocysteine Levels in Relation to p53 Expression in Megaloblastic Anemia. PloS one. vol 11. issue 10. 2017-06-13. PMID:27780269. |
furthermore, it is also not fully known whether decreased vitamin-b12 and / or folate are responsible for apoptosis induction mediated by p53 in pre-erythroblasts. |
2017-06-13 |
2023-08-13 |
Not clear |
| Yan-Yan Sun, Lei Xiao, Dong Wang, Yan-Chao Ji, Yu-Peng Yang, Rong Ma, Xi-Hai Che. Triptolide inhibits viability and induces apoptosis in liver cancer cells through activation of the tumor suppressor gene p53. International journal of oncology. vol 50. issue 3. 2017-06-13. PMID:28098861. |
triptolide inhibits viability and induces apoptosis in liver cancer cells through activation of the tumor suppressor gene p53. |
2017-06-13 |
2023-08-13 |
Not clear |
| Yan-Yan Sun, Lei Xiao, Dong Wang, Yan-Chao Ji, Yu-Peng Yang, Rong Ma, Xi-Hai Che. Triptolide inhibits viability and induces apoptosis in liver cancer cells through activation of the tumor suppressor gene p53. International journal of oncology. vol 50. issue 3. 2017-06-13. PMID:28098861. |
treatment of hepg2 cells with p53 inhibitor, pifithrin-α prior to incubation with triptolide significantly prevented induction of cell apoptosis. |
2017-06-13 |
2023-08-13 |
Not clear |
| Yan-Yan Sun, Lei Xiao, Dong Wang, Yan-Chao Ji, Yu-Peng Yang, Rong Ma, Xi-Hai Che. Triptolide inhibits viability and induces apoptosis in liver cancer cells through activation of the tumor suppressor gene p53. International journal of oncology. vol 50. issue 3. 2017-06-13. PMID:28098861. |
suppression of p53 expression by sirna inhibited the expression of p53 as well as its target genes along with the prevention of apoptosis induction. |
2017-06-13 |
2023-08-13 |
Not clear |
| Yan-Yan Sun, Lei Xiao, Dong Wang, Yan-Chao Ji, Yu-Peng Yang, Rong Ma, Xi-Hai Che. Triptolide inhibits viability and induces apoptosis in liver cancer cells through activation of the tumor suppressor gene p53. International journal of oncology. vol 50. issue 3. 2017-06-13. PMID:28098861. |
in conclusion, triptolide inhibits viability and induces apoptosis in liver cancer cells through activation of the tumor suppressor gene p53. |
2017-06-13 |
2023-08-13 |
Not clear |
| Bor-Chin Cheng, Jui-Tai Chen, Shun-Tai Yang, Chung-Ching Chio, Shing-Hwa Liu, Ruei-Ming Che. Cobalt chloride treatment induces autophagic apoptosis in human glioma cells via a p53-dependent pathway. International journal of oncology. vol 50. issue 3. 2017-06-13. PMID:28197638. |
application of p53 small interference (si)rna into human u87-mg cells downregulated levels of this protein and simultaneously lowered hypoxia- and 3-ma-induced alterations in cell autophagy, apoptosis, and death. |
2017-06-13 |
2023-08-13 |
human |
| Bor-Chin Cheng, Jui-Tai Chen, Shun-Tai Yang, Chung-Ching Chio, Shing-Hwa Liu, Ruei-Ming Che. Cobalt chloride treatment induces autophagic apoptosis in human glioma cells via a p53-dependent pathway. International journal of oncology. vol 50. issue 3. 2017-06-13. PMID:28197638. |
the hypoxia-induced autophagy and apoptosis of dbtrg-05mg cells were significantly lowered by 3-ma pretreatment and p53 knockdown. |
2017-06-13 |
2023-08-13 |
human |
| Jian-Nan Li, Ye Yu, Yan-Fei Zhang, Zhi-Meng Li, Guang-Zhi Cai, Ji-Yu Gon. Synergy of Raddeanin A and cisplatin induced therapeutic effect enhancement in human hepatocellular carcinoma. Biochemical and biophysical research communications. vol 485. issue 2. 2017-06-13. PMID:28219642. |
interestingly, the molecule signals correlated to tumor cell apoptosis containing both of p53 and bax are simultaneously activated, but bcl-2 and survivin are all depressed in mrna level. |
2017-06-13 |
2023-08-13 |
human |
| Nicholas W Fischer, Aaron Prodeus, David Malkin, Jean Gariép. p53 oligomerization status modulates cell fate decisions between growth, arrest and apoptosis. Cell cycle (Georgetown, Tex.). vol 15. issue 23. 2017-06-12. PMID:27754743. |
p53 oligomerization status modulates cell fate decisions between growth, arrest and apoptosis. |
2017-06-12 |
2023-08-13 |
Not clear |
| Nicholas W Fischer, Aaron Prodeus, David Malkin, Jean Gariép. p53 oligomerization status modulates cell fate decisions between growth, arrest and apoptosis. Cell cycle (Georgetown, Tex.). vol 15. issue 23. 2017-06-12. PMID:27754743. |
activation of p53 through tetramerization is required for its tumor suppressive function by inducing transcriptional programs that lead to cell fate decisions such as cell cycle arrest or apoptosis. |
2017-06-12 |
2023-08-13 |
Not clear |
| Nicholas W Fischer, Aaron Prodeus, David Malkin, Jean Gariép. p53 oligomerization status modulates cell fate decisions between growth, arrest and apoptosis. Cell cycle (Georgetown, Tex.). vol 15. issue 23. 2017-06-12. PMID:27754743. |
we report that dimeric p53 variants are cytostatic and can arrest cell growth, but lack the ability to trigger apoptosis in p53-null cells. |
2017-06-12 |
2023-08-13 |
Not clear |
| Nicholas W Fischer, Aaron Prodeus, David Malkin, Jean Gariép. p53 oligomerization status modulates cell fate decisions between growth, arrest and apoptosis. Cell cycle (Georgetown, Tex.). vol 15. issue 23. 2017-06-12. PMID:27754743. |
in contrast, p53 tetramers induce rapid apoptosis and cell growth arrest, while a monomeric variant is functionally inactive, supporting cell growth. |
2017-06-12 |
2023-08-13 |
Not clear |
| Shinji Yasuhira, Masahiko Shibazaki, Masao Nishiya, Chihaya Maesaw. Paclitaxel-induced aberrant mitosis and mitotic slippage efficiently lead to proliferative death irrespective of canonical apoptosis and p53. Cell cycle (Georgetown, Tex.). vol 15. issue 23. 2017-06-12. PMID:27764550. |
paclitaxel-induced aberrant mitosis and mitotic slippage efficiently lead to proliferative death irrespective of canonical apoptosis and p53. |
2017-06-12 |
2023-08-13 |
Not clear |
| Shinji Yasuhira, Masahiko Shibazaki, Masao Nishiya, Chihaya Maesaw. Paclitaxel-induced aberrant mitosis and mitotic slippage efficiently lead to proliferative death irrespective of canonical apoptosis and p53. Cell cycle (Georgetown, Tex.). vol 15. issue 23. 2017-06-12. PMID:27764550. |
our results suggest that once cells have committed to slippage or aberrant mitosis they eventually undergo proliferative death irrespective of canonical apoptosis or p53 function. |
2017-06-12 |
2023-08-13 |
Not clear |
| Yong Yi, Deshi Chen, Juan Ao, Shengnan Sun, Min Wu, Xiaorong Li, Johann Bergholz, Yujun Zhang, Zhi-Xiong Xia. Metformin Promotes AMP-activated Protein Kinase-independent Suppression of ΔNp63α Protein Expression and Inhibits Cancer Cell Viability. The Journal of biological chemistry. vol 292. issue 13. 2017-06-12. PMID:28193839. |
in this study, we report that, under glucose deprivation, metformin inhibited expression of Δnp63α, a p53 family member involved in cell adhesion pathways, resulting in disruption of cell matrix adhesion and subsequent apoptosis in human squamous carcinoma cells. |
2017-06-12 |
2023-08-13 |
human |
| Esra Baytak, Qiang Gong, Burcu Akman, Hongling Yuan, Wing C Chan, Can Küçü. Whole transcriptome analysis reveals dysregulated oncogenic lncRNAs in natural killer/T-cell lymphoma and establishes MIR155HG as a target of PRDM1. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 39. issue 5. 2017-06-12. PMID:28468592. |
expression of zfas1, which is upregulated in natural killer/t-cell lymphoma cases, showed association with growth-regulating pathways such as stabilization of p53, regulation of apoptosis, cell cycle, or nuclear factor-kappa b signaling in normal and neoplastic natural killer cell samples. |
2017-06-12 |
2023-08-13 |
Not clear |
| Federica Rizzo, Dario Ronchi, Sabrina Salani, Monica Nizzardo, Francesco Fortunato, Andreina Bordoni, Giulia Stuppia, Roberto Del Bo, Daniela Piga, Romana Fato, Nereo Bresolin, Giacomo P Comi, Stefania Cort. Selective mitochondrial depletion, apoptosis resistance, and increased mitophagy in human Charcot-Marie-Tooth 2A motor neurons. Human molecular genetics. vol 25. issue 19. 2017-06-09. PMID:27506976. |
p53, bax, caspase 8, cleaved caspase 3, and the anti-apoptotic marker bcl2) demonstrated that cmt2a-mns are more resistant to apoptosis than wild-type mns. |
2017-06-09 |
2023-08-13 |
human |
| Geun-Hee Kwak, Hwa-Young Ki. MsrB3 deficiency induces cancer cell apoptosis through p53-independent and ER stress-dependent pathways. Archives of biochemistry and biophysics. vol 621. 2017-06-09. PMID:28389299. |
in this study, we investigated whether p53 and endoplasmic reticulum (er) stress are involved in msrb3 deficiency-induced cancer cell apoptosis using breast and colon cancer cells. |
2017-06-09 |
2023-08-13 |
Not clear |
| Nicolas J Barthelery, James J Manfred. Cerebellum Development and Tumorigenesis: A p53-Centric Perspective. Trends in molecular medicine. vol 22. issue 5. 2017-06-09. PMID:27085812. |
p53 has been associated with the induction of a variety of cellular outcomes including cell cycle arrest, senescence, and apoptosis. |
2017-06-09 |
2023-08-13 |
Not clear |