| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chien-Feng Li, Ti-Chun Chan, Cheng-Tang Pan, Pichpisith Pierre Vejvisithsakul, Jia-Chen Lai, Szu-Yu Chen, Ya-Wen Hsu, Meng-Shin Shiao, Yow-Ling Shiu. Correction to: EMP2 induces cytostasis and apoptosis via the TGFβ/SMAD/SP1 axis and recruitment of P2RX7 in urinary bladder urothelial carcinoma. Cellular oncology (Dordrecht, Netherlands). 2024-09-03. PMID:39225904. |
correction to: emp2 induces cytostasis and apoptosis via the tgfβ/smad/sp1 axis and recruitment of p2rx7 in urinary bladder urothelial carcinoma. |
2024-09-03 |
2024-09-05 |
Not clear |
| Cheng Cheng, Jiaoyao Ma, Xiaoling Lu, Panpan Zhang, Xiaohan Wang, Luo Guo, Peifan Li, Ying Wei, Geng-Lin Li, Xia Gao, Yuqiu Zhang, Renjie Chai, Huawei Li, Shan Su. P2X7 receptor is required for the ototoxicity caused by aminoglycoside in developing cochlear hair cells. Neurobiology of disease. 2023-06-01. PMID:37263384. |
in addition, knocking-out p2rx7 did not significantly alter the hc count and auditory signal transduction, but it did inhibit mitochondria-dependent oxidative stress and apoptosis in the cochlea after neomycin exposure. |
2023-06-01 |
2023-08-14 |
mouse |
| Chien-Feng Li, Ti-Chun Chan, Cheng-Tang Pan, Pichpisith Pierre Vejvisithsakul, Jia-Chen Lai, Szu-Yu Chen, Ya-Wen Hsu, Meng-Shin Shiao, Yow-Ling Shiu. EMP2 induces cytostasis and apoptosis via the TGFβ/SMAD/SP1 axis and recruitment of P2RX7 in urinary bladder urothelial carcinoma. Cellular oncology (Dordrecht). vol 44. issue 5. 2021-10-15. PMID:34339014. |
emp2 induces cytostasis and apoptosis via the tgfβ/smad/sp1 axis and recruitment of p2rx7 in urinary bladder urothelial carcinoma. |
2021-10-15 |
2023-08-13 |
Not clear |
| Mohammad Javad Mousavi, Elham Farhadi, Mohammad Vodjgani, Jafar Karami, Mohammad Naghi Tahmasebi, Arash Sharafat Vaziri, Marzieh Asgari, Nima Rezaei, Shayan Mostafaei, Ahmadreza Jamshidi, Mahdi Mahmoud. Role of Fibroblast Activation Protein Alpha in Fibroblast-like Synoviocytes of Rheumatoid Arthritis. Iranian journal of allergy, asthma, and immunology. vol 20. issue 3. 2021-06-17. PMID:34134455. |
flss were divided into un-treated and talabostat-treated groups to evaluate the fap-α effect on the selected genes involved in cell cycle regulation (p21, p53, ccnd1), apoptosis (bcl-2, puma), and inflammatory and destructive behavior of flss (il-6, tgf-β1, mmp-2, mmp-9, p2rx7). |
2021-06-17 |
2023-08-13 |
Not clear |
| Jingjing Ding, Yanfei Cong, Fang Li, Bo Liu, Di Wu, Jianing Miao, Lili Wan. Muscle death participates in myofibrillar abnormalities in FHL1 knockout mice. Biochemical and biophysical research communications. vol 523. issue 1. 2020-09-10. PMID:31836140. |
p2rx7 induces cell death, such as autophagy, pyroptosis or apoptosis via cell-specific downstream signaling; however, the roles of p2rx7 in pyroptosis or apoptosis in myofibrillar abnormalities in fhl1 ko mice have not been well elucidated. |
2020-09-10 |
2023-08-13 |
mouse |
| Shulong J Hu, Bertrand Calippe, Sophie Lavalette, Christophe Roubeix, Fadoua Montassar, Michael Housset, Olivier Levy, Cecile Delarasse, Michel Paques, José-Alain Sahel, Florian Sennlaub, Xavier Guillonnea. Upregulation of P2RX7 in Cx3cr1-Deficient Mononuclear Phagocytes Leads to Increased Interleukin-1β Secretion and Photoreceptor Neurodegeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 18. 2015-07-24. PMID:25948251. |
p2rx7 and il-1β inhibition efficiently blunted cx3cr1-mp-dependent photoreceptor apoptosis in a monocyte/retina coculture system and in light-induced subretinal inflammation of cx3cr1-deficient mice in vivo. |
2015-07-24 |
2023-08-13 |
mouse |
| Paul Hofman, Julien Cherfils-Vicini, Marie Bazin, Marius Ilie, Thierry Juhel, Xavier Hébuterne, Eric Gilson, Annie Schmid-Alliana, Olivier Boyer, Sahil Adriouch, Valérie Vouret-Craviar. Genetic and pharmacological inactivation of the purinergic P2RX7 receptor dampens inflammation but increases tumor incidence in a mouse model of colitis-associated cancer. Cancer research. vol 75. issue 5. 2015-04-30. PMID:25564520. |
p2rx7 blockade enhanced proliferation of intestinal epithelial cells and protected them from apoptosis. |
2015-04-30 |
2023-08-13 |
mouse |
| Anfei Huang, Haitao Zhang, Si Chen, Fei Xia, Yi Yang, Fulu Dong, Di Sun, Sidong Xiong, Jinping Zhan. miR-34a expands myeloid-derived suppressor cells via apoptosis inhibition. Experimental cell research. vol 326. issue 2. 2014-09-26. PMID:24780820. |
the distinct mrna microarray profiles of mdscs of wild type and mir-34a over-expressing mdscs combined with the target prediction of mir-34a suggest that mir-34a may target genes such as p2rx7, tia1, and plekhf1 to inhibit the apoptosis of mdscs. |
2014-09-26 |
2023-08-13 |
mouse |
| Shoji Notomi, Toshio Hisatomi, Yusuke Murakami, Hiroto Terasaki, Shozo Sonoda, Ryo Asato, Atsunobu Takeda, Yasuhiro Ikeda, Hiroshi Enaida, Taiji Sakamoto, Tatsuro Ishibash. Dynamic increase in extracellular ATP accelerates photoreceptor cell apoptosis via ligation of P2RX7 in subretinal hemorrhage. PloS one. vol 8. issue 1. 2013-07-02. PMID:23308196. |
these hallmarks of photoreceptor cell apoptosis were prevented by brilliant blue g (bbg), a selective p2rx7 antagonist, which is an approved adjuvant in ocular surgery. |
2013-07-02 |
2023-08-12 |
mouse |
| Shoji Notomi, Toshio Hisatomi, Yusuke Murakami, Hiroto Terasaki, Shozo Sonoda, Ryo Asato, Atsunobu Takeda, Yasuhiro Ikeda, Hiroshi Enaida, Taiji Sakamoto, Tatsuro Ishibash. Dynamic increase in extracellular ATP accelerates photoreceptor cell apoptosis via ligation of P2RX7 in subretinal hemorrhage. PloS one. vol 8. issue 1. 2013-07-02. PMID:23308196. |
dynamic increase in extracellular atp accelerates photoreceptor cell apoptosis via ligation of p2rx7 in subretinal hemorrhage. |
2013-07-02 |
2023-08-12 |
mouse |
| Shoji Notomi, Toshio Hisatomi, Yusuke Murakami, Hiroto Terasaki, Shozo Sonoda, Ryo Asato, Atsunobu Takeda, Yasuhiro Ikeda, Hiroshi Enaida, Taiji Sakamoto, Tatsuro Ishibash. Dynamic increase in extracellular ATP accelerates photoreceptor cell apoptosis via ligation of P2RX7 in subretinal hemorrhage. PloS one. vol 8. issue 1. 2013-07-02. PMID:23308196. |
finally, in a mouse model of subretinal hemorrhage, photoreceptor cells degenerated through bbg-inhibitable apoptosis, suggesting that ligation of p2rx7 by extracellular atp may accelerate photoreceptor cell apoptosis in amd with subretinal hemorrhage. |
2013-07-02 |
2023-08-12 |
mouse |
| Shoji Notomi, Toshio Hisatomi, Takaaki Kanemaru, Atsunobu Takeda, Yasuhiro Ikeda, Hiroshi Enaida, Guido Kroemer, Tatsuro Ishibash. Critical involvement of extracellular ATP acting on P2RX7 purinergic receptors in photoreceptor cell death. The American journal of pathology. vol 179. issue 6. 2012-02-09. PMID:21983632. |
all hallmarks of photoreceptor apoptosis were prevented by premedication or co-application of brilliant blue g, a selective p2rx7 antagonist that is already approved for the staining of internal limiting membranes during ocular surgery. |
2012-02-09 |
2023-08-12 |
mouse |
| Monica L Gavala, Lindsay M Hill, Lisa Y Lenertz, Maya R Karta, Paul J Bertic. Activation of the transcription factor FosB/activating protein-1 (AP-1) is a prominent downstream signal of the extracellular nucleotide receptor P2RX7 in monocytic and osteoblastic cells. The Journal of biological chemistry. vol 285. issue 44. 2010-11-16. PMID:20813842. |
continuous exposure of p2rx7 to ligand can result in apoptosis in many cell types, including monocytic cells, whereas transient activation of p2rx7 is linked to inflammatory mediator production and the promotion of cell growth. |
2010-11-16 |
2023-08-12 |
mouse |