| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ssu-Yu Chen, Jianli Wu, Yubin Chen, Ya-En Wang, Yasaman Setayeshpour, Chiara Federico, Alexander A Mestre, Chao-Chieh Lin, Jen-Tsan Ch. NINJ1 regulates ferroptosis via xCT antiporter interaction and CoA modulation. Cell death & disease. vol 15. issue 10. 2024-10-18. PMID:39424803. |
ninjurin-1 (ninj1), initially identified as a stress-induced protein in neurons, recently emerged as a key mediator of plasma membrane rupture (pmr) during apoptosis, necrosis, and pyroptosis. |
2024-10-18 |
2024-10-21 |
Not clear |
| Ssu-Yu Chen, Chao-Chieh Lin, Jianli Wu, Yubin Chen, Ya-En Wang, Yasaman Setayeshpour, Alexander Mestre, Jen-Tsan Ch. NINJ1 regulates ferroptosis via xCT antiporter interaction and CoA modulation. bioRxiv : the preprint server for biology. 2024-03-11. PMID:38464226. |
ninjurin-1 (ninj1), initially identified as a stress-induced protein in neurons, recently emerged as a key mediator of plasma membrane rupture during apoptosis, necrosis, and pyroptosis. |
2024-03-11 |
2024-03-14 |
Not clear |
| Nobuhiko Kayagaki, Irma B Stowe, Kamela Alegre, Ishan Deshpande, Shuang Wu, Zhonghua Lin, Opher S Kornfeld, Bettina L Lee, Juan Zhang, John Liu, Eric Suto, Wyne P Lee, Kellen Schneider, WeiYu Lin, Dhaya Seshasayee, Tushar Bhangale, Cecile Chalouni, Matthew C Johnson, Prajakta Joshi, Jan Mossemann, Sarah Zhao, Danish Ali, Neil M Goldenberg, Blayne A Sayed, Benjamin E Steinberg, Kim Newton, Joshua D Webster, Ryan L Kelly, Vishva M Dixi. Inhibiting membrane rupture with NINJ1 antibodies limits tissue injury. Nature. 2023-05-17. PMID:37196676. |
plasma membrane rupture (pmr) in dying cells undergoing pyroptosis or apoptosis requires the cell-surface protein ninj1 |
2023-05-17 |
2023-08-14 |
Not clear |
| Min Woo Kim, Ju-Hee Kang, Hyun Jin Jung, Se Yong Park, Jong-Ik Hwang, Je Kyung Seong, Yeo Sung Yoon, Seung Hyun O. Deficiency of Ninjurin1 attenuates LPS/D-galactosamine-induced acute liver failure by reducing TNF-α-induced apoptosis in hepatocytes. Journal of cellular and molecular medicine. 2022-09-07. PMID:36071453. |
also, ninj1 knock-down in l929 and aml12 cells and ninj1 ko in hepg2 cells ameliorated tnf-α-mediated apoptosis. |
2022-09-07 |
2023-08-14 |
mouse |
| Xin Wang, Jinbao Qin, Xing Zhang, Zhiyou Peng, Kaichuang Ye, Xiaoyu Wu, Xinrui Yang, Huihua Shi, Zhen Zhao, Xin Guo, Xiaobing Liu, Minyi Yin, Xinwu L. Functional blocking of Ninjurin1 as a strategy for protecting endothelial cells in diabetes mellitus. Clinical science (London, England : 1979). vol 132. issue 2. 2019-02-11. PMID:29263137. |
nerve injury-induced protein 1 (ninj1) is an adhesion molecule that not only contributes to inflammation but also regulates the apoptosis of endothelial cells. |
2019-02-11 |
2023-08-13 |
mouse |
| Xin Wang, Jinbao Qin, Xing Zhang, Zhiyou Peng, Kaichuang Ye, Xiaoyu Wu, Xinrui Yang, Huihua Shi, Zhen Zhao, Xin Guo, Xiaobing Liu, Minyi Yin, Xinwu L. Functional blocking of Ninjurin1 as a strategy for protecting endothelial cells in diabetes mellitus. Clinical science (London, England : 1979). vol 132. issue 2. 2019-02-11. PMID:29263137. |
additionally, blocking ninj1 inhibited the activation of caspase-3 and increased the bcl-2/bax ratio, thus inhibiting huvecs apoptosis induced by hg. |
2019-02-11 |
2023-08-13 |
mouse |
| Hye-Kyung Lee, Hahnbie Lee, Lidan Luo, Ja-Kyeong Le. Induction of Nerve Injury-Induced Protein 1 (Ninjurin 1) in Myeloid Cells in Rat Brain after Transient Focal Cerebral Ischemia. Experimental neurobiology. vol 25. issue 2. 2016-04-28. PMID:27122992. |
recently, ninj1 was found to act as a modulator of cell migration, angiogenesis, and apoptosis. |
2016-04-28 |
2023-08-13 |
rat |
| Seong-Jun Cho, Andrea Rossi, Yong-Sam Jung, Wensheng Yan, Gang Liu, Jin Zhang, Min Zhang, Xinbin Che. Ninjurin1, a target of p53, regulates p53 expression and p53-dependent cell survival, senescence, and radiation-induced mortality. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 23. 2013-08-06. PMID:23690620. |
taken together, we provided evidence that ninj1 is a p53 target and modulates p53 mrna translation and p53-dependent premature senescence, cell proliferation, apoptosis, and radiation-induced mortality in vitro and in vivo. |
2013-08-06 |
2023-08-12 |
mouse |
| Seong-Jun Cho, Andrea Rossi, Yong-Sam Jung, Wensheng Yan, Gang Liu, Jin Zhang, Min Zhang, Xinbin Che. Ninjurin1, a target of p53, regulates p53 expression and p53-dependent cell survival, senescence, and radiation-induced mortality. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 23. 2013-08-06. PMID:23690620. |
in addition, we found that ninj1 deficiency suppresses cell proliferation but enhances apoptosis and premature senescence in a p53-dependent manner. |
2013-08-06 |
2023-08-12 |
mouse |