All Relations between apoptosis and bud31
Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Liwei Wei, Yisheng Li, Jiawang Chen, Yuanmei Wang, Jianmin Wu, Huanming Yang, Yi Zhan. Alternative splicing in ovarian cancer. Cell communication and signaling : CCS. vol 22. issue 1. 2024-10-19. PMID:39425166. |
additionally, experimental evidence has underscored the potential therapeutic utility of targeting alternative splicing events, exemplified by the observation that knockdown of splicing factor bud31 or antisense oligonucleotide-induced bcl2l12 exon skipping promotes apoptosis of ovarian cancer cells. |
2024-10-19 |
2024-10-21 |
Not clear |
Zixiang Wang, Shourong Wang, Junchao Qin, Xiyu Zhang, Gang Lu, Hongbin Liu, Haiyang Guo, Ligang Wu, Victoria O Shender, Changshun Shao, Beihua Kong, Zhaojian Li. Splicing factor BUD31 promotes ovarian cancer progression through sustaining the expression of anti-apoptotic BCL2L12. Nature communications. vol 13. issue 1. 2022-10-21. PMID:36271053. |
knockdown of bud31 or splice-switching antisense oligonucleotide treatment promotes exon 3 skipping and results in a truncated isoform of bcl2l12 that undergoes nonsense-mediated mrna decay, and the cells subsequently undergo apoptosis. |
2022-10-21 |
2023-08-14 |
Not clear |