| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dan Wu, Peirong Wang, Shiyao Wan. Low levels of Bax inhibitor-1 gene expression increase tunicamycin-induced apoptosis in human neuroblastoma SY5Y cells. Neural regeneration research. vol 7. issue 17. 2015-02-06. PMID:25657664. |
low levels of bax inhibitor-1 gene expression increase tunicamycin-induced apoptosis in human neuroblastoma sy5y cells. |
2015-02-06 |
2023-08-13 |
human |
| Dan Wu, Peirong Wang, Shiyao Wan. Low levels of Bax inhibitor-1 gene expression increase tunicamycin-induced apoptosis in human neuroblastoma SY5Y cells. Neural regeneration research. vol 7. issue 17. 2015-02-06. PMID:25657664. |
in control sh-sy5y cells, tunicamycin treatment induced endoplasmic reticulum stress-mediated apoptosis; however, after bax inhibitor-1 gene knockdown, cell survival rates were significantly decreased and the degree of apoptosis was significantly increased following tunicamycin treatment. |
2015-02-06 |
2023-08-13 |
human |
| Dan Wu, Peirong Wang, Shiyao Wan. Low levels of Bax inhibitor-1 gene expression increase tunicamycin-induced apoptosis in human neuroblastoma SY5Y cells. Neural regeneration research. vol 7. issue 17. 2015-02-06. PMID:25657664. |
our findings indicate that bax inhibitor-1 can delay apoptosis induced by endoplasmic reticulum stress. |
2015-02-06 |
2023-08-13 |
human |
| Syamala Soumyakrishnan, Thomas Divya, Srinivasan Kalayarasan, Narayanan Sriram, Ganapasam Sudhandira. Daidzein exhibits anti-fibrotic effect by reducing the expressions of Proteinase activated receptor 2 and TGFβ1/smad mediated inflammation and apoptosis in Bleomycin-induced experimental pulmonary fibrosis. Biochimie. vol 103. 2015-02-04. PMID:24769130. |
further, daidzein regulated the apoptosis by modulating the expressions of bcl-2, bax and caspase 3. |
2015-02-04 |
2023-08-13 |
rat |
| Bong-Seok Song, Seung-Bin Yoon, Bo-Woong Sim, Young-Hyun Kim, Jae-Jin Cha, Seon-A Choi, Kang-Jin Jeong, Ji-Su Kim, Jae-Won Huh, Sang-Rae Lee, Sang-Hyun Kim, Sun-Uk Kim, Kyu-Tae Chan. Valproic acid enhances early development of bovine somatic cell nuclear transfer embryos by alleviating endoplasmic reticulum stress. Reproduction, fertility, and development. vol 26. issue 3. 2015-02-02. PMID:23506644. |
furthermore, vpa greatly reduced cell apoptosis in scnt blastocysts, which was further evidenced by the increased levels of the anti-apoptotic transcript bcl-xl and decreased level of the pro-apoptotic transcript bax. |
2015-02-02 |
2023-08-12 |
cattle |
| Christian Schwarzer, Zhu Fu, Stacey Shuai, Salil Babbar, Guoping Zhao, Chi Li, Terry E Mache. Pseudomonas aeruginosa homoserine lactone triggers apoptosis and Bak/Bax-independent release of mitochondrial cytochrome C in fibroblasts. Cellular microbiology. vol 16. issue 7. 2015-02-02. PMID:24438098. |
the present work tested the involvement of bak and bax in c12-triggered apoptosis in mouse embryo fibroblasts (mef) by comparing mef isolated from embryos of wild-type (wt) and bax(-/-) /bak(-/-) (dko) mice. |
2015-02-02 |
2023-08-12 |
mouse |
| Xiaonan Lv, Peng Wang, Ru Bai, Yingying Cong, Siqingaowa Suo, Xiaofeng Ren, Chunying Che. Inhibitory effect of silver nanomaterials on transmissible virus-induced host cell infections. Biomaterials. vol 35. issue 13. 2015-02-02. PMID:24524838. |
tgev infection induced the occurring of apoptosis in swine testicle (st) cells, down-regulated the expression of bcl-2, up-regulated the expression of bax, altered mitochondrial membrane potential, activated p38 mapk signal pathway, and increased expression of p53 as evidenced by immunofluorescence assays, real-time pcr, flow cytometry and western blot. |
2015-02-02 |
2023-08-12 |
Not clear |
| Began Gopalan, Karthikeyan Narayanan, Zhiyuan Ke, Ting Lu, Yugen Zhang, Lang Zhu. Therapeutic effect of a multi-targeted imidazolium compound in hepatocellular carcinoma. Biomaterials. vol 35. issue 26. 2015-02-02. PMID:24912819. |
ibn-65 dose-dependently arrested cell cycle at g1 phase and was associated with the down-regulation of the cyclin-dependent kinase-4, -6, cyclin d1, and cyclin e. in addition, ibn-65 induced apoptosis by down-regulating survivin, bcl-2 and up-regulating bax, leading to sequential activation of caspase-3, caspase-9 and the cleavage of poly(adp-ribose) polymerase (parp). |
2015-02-02 |
2023-08-13 |
mouse |
| Joo-Young Kim, Bo-Rim Yi, Ryeo-Eun Go, Kyung-A Hwang, Ki-Hoan Nam, Kyung-Chul Cho. Methoxychlor and triclosan stimulates ovarian cancer growth by regulating cell cycle- and apoptosis-related genes via an estrogen receptor-dependent pathway. Environmental toxicology and pharmacology. vol 37. issue 3. 2015-01-29. PMID:24835555. |
as results, mxc and tcs induced bg-1 cell growth via regulating cyclin d1, p21 and bax genes related with cell cycle and apoptosis. |
2015-01-29 |
2023-08-13 |
Not clear |
| Basse Mame Birame, Wang Jigui, Yu Fuxian, Sun Jiazeng, Li Zhili, Liu Weiqua. Potentiation of Apoptin-induced apoptosis by Cecropin B-like antibacterial peptide ABPs1 in human HeLa cervical cancer cell lines is associated with membrane pore formation and caspase-3 activation. Journal of microbiology and biotechnology. vol 24. issue 6. 2015-01-26. PMID:24633228. |
taken together, our study suggests that abps1 combined with apoptin significantly inhibits hela cell proliferation, and induces cell apoptosis through membrane defects, up-regulation of bax expression, down-regulation of survivin expression, and activation of the caspase-3 pathway. |
2015-01-26 |
2023-08-12 |
human |
| Jian Zhang, Ju Wang, Jiu-Yang Jiang, Shang-Dian Liu, Kai Fu, Hong-Yu Li. Tanshinone IIA induces cytochrome c-mediated caspase cascade apoptosis in A549 human lung cancer cells via the JNK pathway. International journal of oncology. vol 45. issue 2. 2015-01-26. PMID:24888720. |
furthermore, tsiia induced a549 cell apoptosis as confirmed by typical morphological changes, with cytochrome c release from the mitochondria and bax translocation to the mitochondria. |
2015-01-26 |
2023-08-13 |
human |
| Lindsey L Kennedy, Laura A Hargrove, Allyson B Graf, Taylor C Francis, Kyle M Hodges, Quy P Nguyen, Yoshi Ueno, John F Greene, Fanyin Meng, Victoria D Huynh, Heather L Franci. Inhibition of mast cell-derived histamine secretion by cromolyn sodium treatment decreases biliary hyperplasia in cholestatic rodents. Laboratory investigation; a journal of technical methods and pathology. vol 94. issue 12. 2015-01-26. PMID:25365204. |
we assessed apoptosis using real-time pcr and ihc for bax. |
2015-01-26 |
2023-08-13 |
rat |
| Lin Zhang, Shilei Wang, Huanli Dong, Yu Li, Peng Wang, Shuhong Li, Yunliang Guo, Ruyong Ya. Spermine attenuates the preconditioning of diazoxide against transient focal cerebral ischemia in rats. Neurological research. vol 36. issue 7. 2015-01-24. PMID:24620960. |
the beneficial effects of diazoxide (improved neurological deficits, decreased infarct volume, and apoptosis, evidenced by the decreased expression of cytochrome c and bax) were significantly neutralized by spermine. |
2015-01-24 |
2023-08-12 |
rat |
| C J Vandenberg, E C Josefsson, K J Campbell, C James, K E Lawlor, B T Kile, S Cor. Loss of Bak enhances lymphocytosis but does not ameliorate thrombocytopaenia in BCL-2 transgenic mice. Cell death and differentiation. vol 21. issue 5. 2015-01-22. PMID:24464220. |
bax and bak are critical effectors of apoptosis. |
2015-01-22 |
2023-08-12 |
mouse |
| Rezan Demiralay, Nesrin Gürsan, Havva Erde. The effects of erdosteine and N-acetylcysteine on apoptotic and antiapoptotic markers in pulmonary epithelial cells in sepsis. The Eurasian journal of medicine. vol 45. issue 3. 2015-01-22. PMID:25610275. |
this study investigated the frequency of apoptosis in rat pulmonary epithelial cells after the injection of an intraperitoneal endotoxin lipopolysaccharide (lps), the effects of lps on apoptotic (bax, caspase-3) and antiapoptotic (bcl-2) markers during lung damage, and the protective effects of two known antioxidant agents, erdosteine and n-acetylcysteine (nac). |
2015-01-22 |
2023-08-13 |
rat |
| Ali Abdullah Alshatwi, Gowhar Shafi, Tarique Noorul Hasan, Naveed Ahmed Syed, Kholoud Khalid Khoj. Fenugreek induced apoptosis in breast cancer MCF-7 cells mediated independently by fas receptor change. Asian Pacific journal of cancer prevention : APJCP. vol 14. issue 10. 2015-01-21. PMID:24289578. |
apoptosis of mcf-7 cells was evidenced by investigating trypan blue exclusion, tunel and caspase 3, 8, 9, p53, fadd, bax and bak by real-time pcr assays inducing activities, in the presence of fme at 65 μg/ml for 24 and 48 hours. |
2015-01-21 |
2023-08-12 |
human |
| Hua-Jun Sun, Lin-Yi Meng, Yang Shen, Yi-Zhun Zhu, Hong-Rui Li. S-benzyl-cysteine-mediated cell cycle arrest and apoptosis involving activation of mitochondrial-dependent caspase cascade through the p53 pathway in human gastric cancer SGC-7901 cells. Asian Pacific journal of cancer prevention : APJCP. vol 14. issue 11. 2015-01-21. PMID:24377536. |
furthermore, western blotting indicated that sbc-induced apoptosis was accompanied by up-regulation of the expression of p53, bax and the down-regulation of bcl-2. |
2015-01-21 |
2023-08-12 |
human |
| Wei-Jun Liu, Jian-Guo Ren, Ting Li, Guo-Zheng Yu, Jin Zhang, Chang-Sheng Li, Zhi-Su Liu, Quan-Yan Li. 5-Aza-2<-deoxycytidine induces hepatoma cell apoptosis via enhancing methionine adenosyltransferase 1A expression and inducing S-adenosylmethionine production. Asian Pacific journal of cancer prevention : APJCP. vol 14. issue 11. 2015-01-21. PMID:24377546. |
furthermore, 5-aza-cdr inhibited the growth of huh7 cells and induced apoptosis and through down-regulation of bcl-2, up-regulation of bax and caspase-3. |
2015-01-21 |
2023-08-12 |
Not clear |
| Jingru Li, Yicheng Chen, Jiali Wan, Xin Liu, Chunrong Yu, Wenhua L. ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21((CIP1/WAF1)) in human cancer cells. British journal of pharmacology. vol 171. issue 13. 2015-01-20. PMID:24571452. |
abt-263 enhances sorafenib-induced apoptosis associated with akt activity and the expression of bax and p21((cip1/waf1)) in human cancer cells. |
2015-01-20 |
2023-08-12 |
human |
| Lu Luo, Jun Yang, Dongxiang Li. Integration and oligomerization of Bax protein in lipid bilayers characterized by single molecule fluorescence study. The Journal of biological chemistry. vol 289. issue 46. 2015-01-20. PMID:25288797. |
the study of bax integration and oligomerization at the single molecule level provides new evidences that may help elucidate the pore formation of bax and its regulatory mechanism in apoptosis. |
2015-01-20 |
2023-08-13 |
Not clear |