| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gaofeng Cui, Yuansheng Li, Kai Ding, Shaodong Hao, Jinzhong Wang, Zhiyong Zhan. Attribution of Bax and mitochondrial permeability transition pore on cantharidin-induced apoptosis of Sf9 cells. Pesticide biochemistry and physiology. vol 142. 2018-01-26. PMID:29107253. |
attribution of bax and mitochondrial permeability transition pore on cantharidin-induced apoptosis of sf9 cells. |
2018-01-26 |
2023-08-13 |
Not clear |
| Gaofeng Cui, Yuansheng Li, Kai Ding, Shaodong Hao, Jinzhong Wang, Zhiyong Zhan. Attribution of Bax and mitochondrial permeability transition pore on cantharidin-induced apoptosis of Sf9 cells. Pesticide biochemistry and physiology. vol 142. 2018-01-26. PMID:29107253. |
to investigate the insecticidal mechanism of cantharidin, a promising biological pesticide substance from blister beetle, on sf9 cells, a cultured cell line derived from fall armyworm, spodoptera frugiperda, we preliminary studied the attribution of bax channel and mitochondrial permeability transition pore on cantharidin-induced mitochondrial apoptosis signal pathway. |
2018-01-26 |
2023-08-13 |
Not clear |
| YanFang Zheng, Yin Zhao, QingQing Luo, XiaoXia Liu, XiaoPing Liu, Ying Hu, Li Zo. Edaravone protects against cobalt chloride-induced dysfunctions in apoptosis and invasion in trophoblast cells. Molecular reproduction and development. vol 83. issue 7. 2018-01-24. PMID:27128210. |
metrics of apoptosis included measurement of cysteine-aspartic acid protease 3 (casp3) activity as well as bax and bcl2 expression. |
2018-01-24 |
2023-08-13 |
Not clear |
| YanFang Zheng, Yin Zhao, QingQing Luo, XiaoXia Liu, XiaoPing Liu, Ying Hu, Li Zo. Edaravone protects against cobalt chloride-induced dysfunctions in apoptosis and invasion in trophoblast cells. Molecular reproduction and development. vol 83. issue 7. 2018-01-24. PMID:27128210. |
cocl2 inhibited the proliferation of h8 cells, promoted apoptosis, and up-regulated casp3 activation and bax expression while inhibiting bcl2 expression. |
2018-01-24 |
2023-08-13 |
Not clear |
| YanFang Zheng, Yin Zhao, QingQing Luo, XiaoXia Liu, XiaoPing Liu, Ying Hu, Li Zo. Edaravone protects against cobalt chloride-induced dysfunctions in apoptosis and invasion in trophoblast cells. Molecular reproduction and development. vol 83. issue 7. 2018-01-24. PMID:27128210. |
edaravone significantly increased h8 cell proliferation; inhibited apoptosis by down-regulating casp3 activation and bax production while promoting bcl2 stability; and ameliorated the migration and invasion phenotypes associated with cocl2 treatment. |
2018-01-24 |
2023-08-13 |
Not clear |
| b' Iva Poto\\xc4\\x8dnjak, Dalibor Brozni\\xc4\\x87, Marija Kindl, Matija Kropek, Sanda Vladimir-Kne\\xc5\\xbeevi\\xc4\\x87, Robert Domitrovi\\xc4\\x8. Stevia and stevioside protect against cisplatin nephrotoxicity through inhibition of ERK1/2, STAT3, and NF-\\xce\\xbaB activation. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 107. issue Pt A. 2018-01-23. PMID:28666887.' |
induction of apoptosis and inhibition of the cell cycle in kidneys was evidenced by increased expression of p53, bax, caspase-9, and p21, proteolytic cleavage of poly (adp-ribose) polymerase (parp), with concomitant suppression of bcl-2 and cyclin d1 expression. |
2018-01-23 |
2023-08-13 |
mouse |
| Amit Kumar Chauhan, Namrata Mittra, Vinod Kumar, Devendra Kumar Patel, Chetna Sing. Inflammation and B-cell Lymphoma-2 Associated X Protein Regulate Zinc-Induced Apoptotic Degeneration of Rat Nigrostriatal Dopaminergic Neurons. Molecular neurobiology. vol 53. issue 8. 2018-01-22. PMID:26497033. |
on the contrary, zn augmented lipid peroxidation, activity of superoxide dismutase, expression of tnf-α, il-1β, bcl-xl, and p53-upregulated modulator of apoptosis (puma), and translocation of nf-κb and bax from the cytosol to the nucleus and mitochondria, respectively, with concomitant increase in the mitochondrial cytochrome c release and activation of procaspase-3 and -9. |
2018-01-22 |
2023-08-13 |
rat |
| Man Liu, Guoren Huang, Thomas T Y Wang, Xiangjun Sun, Liangli Lucy Y. 3-MCPD 1-Palmitate Induced Tubular Cell Apoptosis In Vivo via JNK/p53 Pathways. Toxicological sciences : an official journal of the Society of Toxicology. vol 151. issue 1. 2018-01-22. PMID:27008853. |
additionally, p53 knockout attenuated the apoptosis, and the apoptosis-related protein bax expression and cleaved caspase-3 activation induced by mpe in the p53 knockout c57bl/6 mice, whereas jnk inhibitor sp600125 but not erk inhibitor u0126 inhibited mpe-induced apoptosis, supporting the conclusion that jnk/p53 might play a critical role in the tubular cell apoptosis induced by mpe and other 3-mcpd fatty acid esters. |
2018-01-22 |
2023-08-13 |
mouse |
| Subburayan Karthikeyan, Sugeerappa Laxmanappa Hoti, Yasin Nazeer, Harsha Vasudev Hegd. Glaucarubinone sensitizes KB cells to paclitaxel by inhibiting ABC transporters via ROS-dependent and p53-mediated activation of apoptotic signaling pathways. Oncotarget. vol 7. issue 27. 2018-01-22. PMID:27304668. |
importantly, glu and/or ptx triggered apoptosis through the activation of pro-apoptotic proteins such as p53, bax, and caspase-9. |
2018-01-22 |
2023-08-13 |
human |
| Sharad Verma, Sukriti Goyal, Chetna Tyagi, Salma Jamal, Aditi Singh, Abhinav Grove. BIM (BCL-2 interacting mediator of cell death) SAHB (stabilized α helix of BCL2) not always convinces BAX (BCL-2-associated X protein) for apoptosis. Journal of molecular graphics & modelling. vol 67. 2018-01-19. PMID:27262527. |
bim (bcl-2 interacting mediator of cell death) sahb (stabilized α helix of bcl2) not always convinces bax (bcl-2-associated x protein) for apoptosis. |
2018-01-19 |
2023-08-13 |
Not clear |
| Sharad Verma, Sukriti Goyal, Chetna Tyagi, Salma Jamal, Aditi Singh, Abhinav Grove. BIM (BCL-2 interacting mediator of cell death) SAHB (stabilized α helix of BCL2) not always convinces BAX (BCL-2-associated X protein) for apoptosis. Journal of molecular graphics & modelling. vol 67. 2018-01-19. PMID:27262527. |
the interaction of bax (bcl-2-associated x protein) with bim (bcl-2 interacting mediator of cell death) sahb (stabilized α helix of bcl2) directly initiates bax-mediated mitochondrial apoptosis. |
2018-01-19 |
2023-08-13 |
Not clear |
| Si Shi, Kunbin Guo, Xiangyu Wang, Hao Chen, Jianbin Min, Shuhua Qi, Wei Zhao, Weirong L. Toxicity study of oxalicumone A, derived from a marine-derived fungus Penicillium oxalicum, in cultured renal epithelial cells. Molecular medicine reports. vol 15. issue 5. 2018-01-19. PMID:28260084. |
the results indicated that poa inhibited hk-2 cell growth and promoted apoptosis, by increasing levels of fas cell surface cell receptor and the b‑cell lymphoma 2 associated protein x apoptosis regulator (bax)/b‑cell lymphoma 2 apoptosis regulator (bcl-2) ratio. |
2018-01-19 |
2023-08-13 |
human |
| Hua-Dong Zhao, Hai-Li Tang, Ning-Ning Liu, Ya-Li Zhao, Qin-Qin Liu, Xiao-Shan Zhu, Lin-Tao Jia, Chun-Fang Gao, An-Gang Yang, Jun-Tang L. Targeting ubiquitin-specific protease 22 suppresses growth and metastasis of anaplastic thyroid carcinoma. Oncotarget. vol 7. issue 21. 2018-01-18. PMID:27145278. |
in vitro assays showed that usp22 depletion suppressed atc cell survival and proliferation by decreasing rb phosphorylation and cyclin d2, inactivating akt, and simultaneously upregulating rb; usp22 silencing restrained cell migration and invasion by inhibiting epithelial-mesenchymal transition; usp22 knockdown promoted mitochondrion- mediated and caspase-dependent apoptosis by upregulating bax and bid and promoting caspase-3 activation. |
2018-01-18 |
2023-08-13 |
Not clear |
| Daw-Shyong Perng, Yu-Hsin Tsai, Jonathan Cherng, Chih-Wei Kuo, Chih-Chung Shiao, Jaw-Ming Chern. Discovery of a novel anti-cancer agent targeting both topoisomerase I and II in hepatocellular carcinoma Hep 3B cells in vitro and in vivo: Cinnamomum verum component 2-methoxycinnamaldehyde. Journal of drug targeting. vol 24. issue 7. 2018-01-17. PMID:26707867. |
the results show that 2-mca suppressed proliferation and induced apoptosis as indicated by an up-regulation of pro-apoptotic bax and bak genes and down-regulation of anti-apoptotic bcl-2 and bcl-xl genes, mitochondrial membrane potential loss, cytochrome c release, activation of caspase 3 and 9, increase in the dna content in sub g1, and morphological characteristics of apoptosis. |
2018-01-17 |
2023-08-13 |
mouse |
| Shuang-An Li, Wei-Dan Jiang, Lin Feng, Yang Liu, Pei Wu, Jun Jiang, Sheng-Yao Kuang, Ling Tang, Wu-Neng Tang, Yong-An Zhang, Xu Tang, He-Qun Shi, Xiao-Qiu Zho. Dietary myo-inositol deficiency decreased the growth performances and impaired intestinal physical barrier function partly relating to nrf2, jnk, e2f4 and mlck signaling in young grass carp (Ctenopharyngodon idella). Fish & shellfish immunology. vol 67. 2018-01-17. PMID:28610850. |
(2) up-regulated cysteinyl aspartic acid-protease (caspase)-2, -3, -7, -8, -9, apoptotic protease activating factor-1 (apaf-1), bcl2-associated x protein (bax), fas ligand (fasl), gen-activated protein kinase (p38mapk) and c-jun n-terminal protein kinase (jnk) mrna levels, whereas down-regulated b-cell lymphoma-2 (bcl-2), inhibitor of apoptosis proteins (iap) and myeloid cell leukemia-1 (mcl-1) mrna levels in three intestinal segments of young grass carp (p < 0.05). |
2018-01-17 |
2023-08-13 |
Not clear |
| M M Flórez, H B Fêo, G N da Silva, R S Yamatogi, A J Aguiar, J P Araújo, N S Roch. Cell cycle kinetics, apoptosis rates and gene expressions of MDR-1, TP53, BCL-2 and BAX in transmissible venereal tumour cells and their association with therapy response. Veterinary and comparative oncology. vol 15. issue 3. 2018-01-16. PMID:26879698. |
cell cycle kinetics, apoptosis rates and gene expressions of mdr-1, tp53, bcl-2 and bax in transmissible venereal tumour cells and their association with therapy response. |
2018-01-16 |
2023-08-13 |
Not clear |
| Rouba Hage-Sleiman, Hisham Bahmad, Hadile Kobeissy, Zeinab Dakdouk, Firas Kobeissy, Ghassan Dbaib. Genomic alterations during p53-dependent apoptosis induced by γ-irradiation of Molt-4 leukemia cells. PloS one. vol 12. issue 12. 2018-01-16. PMID:29272311. |
similarly, at 8 hours the genes with altered expression were involved in the apoptosis signaling pathway (bax, bik and jun), p53 pathway (bax, cdkn1a and fas), oxidative stress response (fdxr and crot) and p53 pathway feedback loops 2 (mdm2 and cdkn1a). |
2018-01-16 |
2023-08-13 |
human |
| Aditi Banerjee, Hafiz Ahmed, Peixin Yang, Steven J Czinn, Thomas G Blanchar. Endoplasmic reticulum stress and IRE-1 signaling cause apoptosis in colon cancer cells in response to andrographolide treatment. Oncotarget. vol 7. issue 27. 2018-01-12. PMID:27166181. |
apoptosis signaling molecules bax, spliced xbp-1 and chop were also significantly increased. |
2018-01-12 |
2023-08-13 |
Not clear |
| Chun-Li Song, Bin Liu, Hong-Ying Diao, Yong-Feng Shi, Ji-Chang Zhang, Yang-Xue Li, Ning Liu, Yun-Peng Yu, Guan Wang, Jin-Peng Wang, Qian L. Down-regulation of microRNA-320 suppresses cardiomyocyte apoptosis and protects against myocardial ischemia and reperfusion injury by targeting IGF-1. Oncotarget. vol 7. issue 26. 2018-01-12. PMID:27175593. |
compared to h/r + nc group in vitro, mir-320 inhibition increased igf-1 mrna levels, inhibited cardiomyocyte apoptosis, down-regulated p-ask, p-jnk, p-p38, bax and caspase-3 levels, and up-regulated bcl-2 level. |
2018-01-12 |
2023-08-13 |
rat |
| Natarajan Suganthy, Dicson Sheeja Malar, Kasi Pandima Dev. Rhizophora mucronata attenuates beta-amyloid induced cognitive dysfunction, oxidative stress and cholinergic deficit in Alzheimer's disease animal model. Metabolic brain disease. vol 31. issue 4. 2018-01-12. PMID:27188290. |
furthermore, merm attenuated lipid peroxidation, protein oxidation, restored the antioxidant status and inhibited neuronal apoptosis by down-regulating the level of caspase 3 and bax protein. |
2018-01-12 |
2023-08-13 |
mouse |