| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qingling Mu, Xin Wang, Kui Huang, Baoguo Xia, Shuna Bi, Yujie Kon. THUMPD3-AS1 inhibits ovarian cancer cell apoptosis through the miR-320d/ARF1 axis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 38. issue 13. 2024-07-04. PMID:38963337. |
additionally, mir-320d overexpression inhibited ovarian cancer cell viability and accelerated apoptosis, which was overturned by overexpression of arf1. |
2024-07-04 |
2024-07-10 |
human |
| Ze-Bo Jiang, Cong Xu, Wenjun Wang, Yi-Zhong Zhang, Ju-Min Huang, Ya-Jia Xie, Qian-Qian Wang, Xing-Xing Fan, Xiao-Jun Yao, Chun Xie, Xuan-Run Wang, Pei-Yu Yan, Yu-Po Ma, Qi-Biao Wu, Elaine Lai-Han Leun. Plumbagin suppresses non-small cell lung cancer progression through downregulating ARF1 and by elevating CD8 Pharmacological research. vol 169. 2021-10-04. PMID:33964470. |
plb promoted ros production, activated the endoplasmic reticulum (er) stress pathway, and induced cell apoptosis, accompanied by the decreased expression level of adp-ribosylation factor 1 (arf1) in nsclc cancer cells, and those effects of plb could be reversed by the pretreatment with n-acetyl-l-cysteine (nac). |
2021-10-04 |
2023-08-13 |
Not clear |
| Mami Sumiyoshi, Yui Kotani, Yuki Ikuta, Kazutomo Suzue, Madoka Ozawa, Tomoya Katakai, Taketo Yamada, Takaya Abe, Kana Bando, Shigeo Koyasu, Yasunori Kanaho, Toshio Watanabe, Satoshi Matsud. Arf1 and Arf6 Synergistically Maintain Survival of T Cells during Activation. Journal of immunology (Baltimore, Md. : 1950). vol 206. issue 2. 2021-05-10. PMID:33310872. |
in contrast, the lack of both arf1 and arf6, but neither arf1 nor arf6 deficiency alone, rendered naive t cells susceptible to apoptosis upon tcr stimulation because of imbalanced expression of bcl-2 family members. |
2021-05-10 |
2023-08-13 |
mouse |
| Charlotte Luchsinger, Marcelo Aguilar, Patricia V Burgos, Pamela Ehrenfeld, Gonzalo A Mardone. Functional disruption of the Golgi apparatus protein ARF1 sensitizes MDA-MB-231 breast cancer cells to the antitumor drugs Actinomycin D and Vinblastine through ERK and AKT signaling. PloS one. vol 13. issue 4. 2018-07-31. PMID:29614107. |
likewise, the combined treatment of cells with actinomycin d or vinblastine and brefeldin a or golgicide a, two disrupting agents of the arf1 function, resulted in similar effects on cell proliferation, cell migration and apoptosis. |
2018-07-31 |
2023-08-13 |
Not clear |
| Takayuki Hattori, Miho Watanabe-Takahashi, Isamu Shiina, Yoshimi Ohashi, Shingo Dan, Kiyotaka Nishikawa, Takao Yamori, Mikihiko Nait. M-COPA, a novel Golgi system disruptor, suppresses apoptosis induced by Shiga toxin. Genes to cells : devoted to molecular & cellular mechanisms. vol 21. issue 8. 2017-02-13. PMID:27302278. |
we report here that 2-methylcoprophilinamide (m-copa), a compound that induces disassembly of the golgi apparatus by inactivating adp-ribosylation factor 1 (arf1), suppresses stx-induced apoptosis. |
2017-02-13 |
2023-08-13 |
Not clear |
| Eric Haines, Sabrina Schlienger, Audrey Clain. The small GTPase ADP-Ribosylation Factor 1 mediates the sensitivity of triple negative breast cancer cells to EGFR tyrosine kinase inhibitors. Cancer biology & therapy. vol 16. issue 10. 2016-09-12. PMID:26176330. |
this may be explained by the observation that the depletion of arf1 suppressed gefitinib-mediated activation of key mediators of survival such as erk1/2, akt and src, while enhancing cascades leading to apoptosis such as the p38mapk and jnk pathways, modifying the bax/bcl2 ratio and cytochrome c release. |
2016-09-12 |
2023-08-13 |
Not clear |
| Maria Rosa Bani, Maria Ines Nicoletti, Nawal W Alkharouf, Carmen Ghilardi, David Petersen, Eugenio Erba, Edward A Sausville, Edison T Liu, Raffaella Giavazz. Gene expression correlating with response to paclitaxel in ovarian carcinoma xenografts. Molecular cancer therapeutics. vol 3. issue 2. 2004-11-22. PMID:14985451. |
most gene expression alterations were detected 24 h after paclitaxel administration and affected genes involved in various biological functions including cell cycle regulation and cell proliferation (cdc2, cdkn1a, plab, and top2a), apoptosis (bnip3 and pig8), signal transduction and transcriptional regulation (arf1, atf2, fos, gna11, hdac3, madh2, slug, and spry4), fatty acid biosynthesis and sterol metabolism (fdps, idi1, lipa, and sc5d), and ifn-mediated signaling (g1p3, ifi16, ifi27, ifitm1, and isg15). |
2004-11-22 |
2023-08-12 |
mouse |