| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anthony F Lacagnina, Tri N Dong, Rasika R Iyer, Leonie F Boesch, Saqib Khan, Mazen K Mohamed, Roger L Cle. Ventral hippocampal interneurons govern extinction and relapse of contextual associations. Cell reports. vol 43. issue 11. 2024-10-19. PMID:39425930. |
these data suggest that ventral hippocampal sst-ins play a fundamental role in extinction that is independent of affective valence and may be related to their disruption of spontaneous emotional responses. |
2024-10-19 |
2024-10-22 |
Not clear |
| Alex Stefanov, Kiralyn Brakel, Josephina Rau, Rose M Joseph, Corey Guice, Kendall Araguz, Annebel Hemphill, Jessica Madry, Andrew Irion, Swapnil Dash, Karienn A Souza, Michelle A Hoo. Depression-like behavior is associated with deficits in cognition and hippocampal neurogenesis in a subset of spinally contused male, but not female, rats. Brain, behavior, and immunity. 2024-09-17. PMID:39288895. |
neurogenesis was also disrupted in only sci males in regions of the hippocampus responsible for affective outcomes. |
2024-09-17 |
2024-09-20 |
human |
| Junseop Lee, Jeongrak Park, Minseok Jeong, Seo-Jin Oh, Jong-Hyuk Yoon, Yong-Seok O. Anatomical topology of extrahippocampal projections from dorsoventral CA pyramidal neurons in mice. Frontiers in neuroanatomy. vol 18. 2024-08-07. PMID:39108929. |
among these, ca pns are known to project beyond the hippocampus into various limbic areas, critically influencing cognitive and affective behaviors. |
2024-08-07 |
2024-08-09 |
mouse |
| Marieka V DeVuono, Mina G Nashed, Mohammed H Sarikahya, Andrea Kocsis, Kendrick Lee, Sebastian R Vanin, Roger Hudson, Eryn P Lonnee, Walter J Rushlow, Daniel B Hardy, Steven R Laviolett. Prenatal tetrahydrocannabinol and cannabidiol exposure produce sex-specific pathophysiological phenotypes in the adolescent prefrontal cortex and hippocampus. Neurobiology of disease. 2024-07-03. PMID:38960101. |
these phenotypes were associated with sex and treatment-specific neuronal and gene transcriptional alterations in the prefrontal cortex, and ventral hippocampus, regions where the endocannabinoid system is implicated in affective and cognitive development. |
2024-07-03 |
2024-07-10 |
rat |
| Jayden A O'Brien, Paul J Austi. Minocycline Abrogates Individual Differences in Nerve Injury-Evoked Affective Disturbances in Male Rats and Prevents Associated Supraspinal Neuroinflammation. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 19. issue 1. 2024-06-15. PMID:38878098. |
individual differences in affective disturbances following nerve injury are therefore temporally related to altered microglial morphology and hippocampal neuronal activation, and are abrogated by minocycline. |
2024-06-15 |
2024-06-18 |
rat |
| Lianqing Zhang, Xinyue Hu, Yongbo Hu, Mengyue Tang, Hui Qiu, Ziyu Zhu, Yingxue Gao, Hailong Li, Weihong Kuang, Weidong J. Structural covariance network of the hippocampus-amygdala complex in medication-naïve patients with first-episode major depressive disorder. Psychoradiology. vol 2. issue 4. 2024-04-26. PMID:38665275. |
the hippocampus and amygdala are densely interconnected structures that work together in multiple affective and cognitive processes that are important to the etiology of major depressive disorder (mdd). |
2024-04-26 |
2024-04-28 |
Not clear |
| Mouloud Lamtai, Hajar Benmhammed, Sofia Azirar, Ayoub Rezqaoui, Oussama Zghari, Abdelghafour El Hamzaoui, Mohamed Yassine El Brouzi, Yassine Chahirou, Samir Bikri, Abdelhalem Mesfioui, Aboubaker El Hessn. Subchronic Exposure to Mixture of Cadmium, Copper, and Nickel Induces Neurobehavioral Deficits and Hippocampal Oxidative Stress of Wistar Rats. Biological trace element research. 2024-04-05. PMID:38578484. |
the present study was aimed at evaluating the influence of the subchronic exposure of cadmium (cd), copper (cu), and nickel (ni) mixtures on affective behaviors, memory impairment, and oxidative stress (os) in the hippocampus. |
2024-04-05 |
2024-04-07 |
rat |
| Mouloud Lamtai, Hajar Benmhammed, Sofia Azirar, Ayoub Rezqaoui, Oussama Zghari, Abdelghafour El Hamzaoui, Mohamed Yassine El Brouzi, Yassine Chahirou, Samir Bikri, Abdelhalem Mesfioui, Aboubaker El Hessn. Subchronic Exposure to Mixture of Cadmium, Copper, and Nickel Induces Neurobehavioral Deficits and Hippocampal Oxidative Stress of Wistar Rats. Biological trace element research. 2024-04-05. PMID:38578484. |
overall, this study underscores that subchronic exposure to the cd, cu, and ni mixture induces an os status and histological changes in the hippocampus, with important affective and cognitive behavior variations in rats. |
2024-04-05 |
2024-04-07 |
rat |
| Saiying Wang, Haijun Zhang, Rui Liu, Peijun Han, Qi Yang, Caiyan Cheng, Yue Chen, Zheng Rong, Chang Su, Fei Li, Gaofei Wei, Minggao Zhao, Le Yan. Influenza A Virus PB1-F2 Induces Affective Disorder by Interfering Synaptic Plasticity in Hippocampal Dentate Gyrus. Molecular neurobiology. 2024-03-15. PMID:38488981. |
in this study, we constructed and injected pb1-f2 into the hippocampal dentate gyrus (dg), a region closely associated with newborn neurons and neural development, to evaluate its influence on negative affective behaviors and learning performance in mice. |
2024-03-15 |
2024-03-18 |
mouse |
| Negar Nikbakht, Martin Pofahl, Albert Miguel-López, Fateme Kamali, Tatjana Tchumatchenko, Heinz Bec. Efficient encoding of aversive location by CA3 long-range projections. Cell reports. vol 43. issue 3. 2024-03-15. PMID:38489262. |
in mammals, the dorsal hippocampus mainly processes spatial information, while the intermediate to ventral hippocampal divisions receive affective information via the amygdala. |
2024-03-15 |
2024-03-18 |
mouse |
| Claudia Sagheddu, Tamara Stojanovic, Shima Kouhnavardi, Artem Savchenko, Ahmed M Hussein, Marco Pistis, Francisco J Monje, Roberto Plasenzotti, Mohammed Aufy, Christian R Studenik, Jana Lubec, Gert Lube. Cognitive performance in aged rats is associated with differences in distinctive neuronal populations in the ventral tegmental area and altered synaptic plasticity in the hippocampus. Frontiers in aging neuroscience. vol 16. 2024-03-12. PMID:38469164. |
the midbrain vta operates as a hub amidst affective and cognitive facets, processing sensory inputs related to motivated behaviours and hippocampal memory. |
2024-03-12 |
2024-03-14 |
rat |
| Alice Hill, Huzefa Khalil, Klaudia Laborc, Savannah Kounelis-Wuillaume, Swapnil Gavade, Colin Johnston, Benjamin H Singer, Joanna L Spencer-Sega. Corticosteroid Treatment During Sepsis Alters Hippocampal Function in Male and Female Survivors. Biological psychiatry global open science. vol 4. issue 1. 2024-02-01. PMID:38298779. |
in light of prior work that has shown persistent inflammation in sepsis survivors, we hypothesized that short-term corticosteroid treatment during illness would reverse the long-term impact of sepsis on inflammatory gene expression in the hippocampus and rescue associated changes to affective behaviors. |
2024-02-01 |
2024-02-03 |
Not clear |
| Yohan J John, Jingyi Wang, Daniel Bullock, Helen Barba. Amygdalar Excitation of Hippocampal Interneurons Can Lead to Emotion-driven Overgeneralization of Context. Journal of cognitive neuroscience. 2024-01-23. PMID:38261402. |
our model revealed an elegant circuit mechanism that mediates an affective "inverted u" phenomenonv: there is an optimal level of amygdalar input that enriches hippocampal context representations, but on either side of this zone, representations are impoverished. |
2024-01-23 |
2024-01-25 |
Not clear |
| Adam Garman, Allison Ash, Ellie Kokkinos, Dakota Nerland, Lori Winter, Cory Langreck, Morgan Forgette, Matthew J Girgenti, Mounira Banasr, Vanja Duri. Novel hippocampal genes involved in enhanced susceptibility to chronic pain-induced behavioral emotionality. European journal of pharmacology. 2023-12-22. PMID:38135263. |
furthermore, differentially expressed genes (degs) were further characterized in rodents stress models to determine whether their hippocampal dysregulation is driven by common stress responses vs. affective pain processing. |
2023-12-22 |
2023-12-25 |
rat |
| Marina Giglberger, Hannah L Peter, Gina-Isabelle Henze, Elisabeth Kraus, Christoph Bärtl, Julian Konzok, Ludwig Kreuzpointner, Peter Kirsch, Brigitte M Kudielka, Stefan Wüs. Neural responses to acute stress predict chronic stress perception in daily life over 13 months. Scientific reports. vol 13. issue 1. 2023-11-15. PMID:37968323. |
the importance of amygdala, hippocampus, and medial prefrontal cortex (mpfc) for the integration of neural, endocrine, and affective stress processing was shown in healthy participants and patients with stress-related disorders. |
2023-11-15 |
2023-11-20 |
human |
| Emily S Nichols, Michael Grace, Susana Correa, Barbra de Vrijer, Roy Eagleson, Charles A McKenzie, Sandrine de Ribaupierre, Emma G Duerde. Sex- and age-based differences in fetal and early childhood hippocampus maturation: a cross-sectional and longitudinal analysis. Cerebral cortex (New York, N.Y. : 1991). 2023-11-11. PMID:37950876. |
the hippocampus, essential for cognitive and affective processes, develops exponentially with differential trajectories seen in girls and boys, yet less is known about its development during early fetal life until early childhood. |
2023-11-11 |
2023-11-20 |
Not clear |
| Marc Dahlmanns, Maria Jesus Valero-Aracama, Jana Katharina Dahlmanns, Fang Zheng, Christian Alzheime. Tonic activin signaling shapes cellular and synaptic properties of CA1 neurons mainly in dorsal hippocampus. iScience. vol 26. issue 10. 2023-10-13. PMID:37829200. |
dorsal and ventral hippocampus serve different functions in cognition and affective behavior, but the underpinnings of this diversity at the cellular and synaptic level are not well understood. |
2023-10-13 |
2023-10-15 |
mouse |
| Veronika Kondev, Mustafa Najeed, Farhana Yasmin, Amanda Morgan, Niharika Loomba, Keenan Johnson, Danielle N Adank, Ao Dong, Eric Delpire, Yulong Li, Danny Winder, Brad A Grueter, Sachin Pate. Endocannabinoid release at ventral hippocampal-amygdala synapses regulates stress-induced behavioral adaptation. Cell reports. 2023-09-13. PMID:37703881. |
the ventral hippocampus (vhpc)-basolateral amygdala (bla) circuit has been implicated in the expression of negative affective states following stress exposure and is modulated by retrograde ecb signaling. |
2023-09-13 |
2023-10-07 |
Not clear |
| Nina Rouhani, Yael Niv, Michael J Frank, Lars Schwab. Multiple routes to enhanced memory for emotionally relevant events. Trends in cognitive sciences. 2023-07-21. PMID:37479601. |
this memory boost is commonly attributed to the elicited affective response, closely linked to noradrenergic and dopaminergic modulation of hippocampal plasticity. |
2023-07-21 |
2023-08-14 |
Not clear |
| Vinícius Fresca da Costa, Johana Caterin Caipa Ramírez, Stephany Viatela Ramírez, Julian Humberto Avalo-Zuluaga, Daniela Baptista-de-Souza, Lucas Canto-de-Souza, Cleopatra S Planeta, Javier Leonardo Rico Rodríguez, Ricardo Luiz Nunes-de-Souz. Emotional- and cognitive-like responses induced by social defeat stress in male mice are modulated by the BNST, amygdala, and hippocampus. Frontiers in integrative neuroscience. vol 17. 2023-06-28. PMID:37377628. |
we hypothesized that these affective, emotional, and cognitive consequences induced by sds are regulated via glutamatergic neurons located in the bed nucleus of the stria terminalis (bnst), amygdaloid complex, and hippocampus in mice. |
2023-06-28 |
2023-08-14 |
mouse |