| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yong Li, Xinyi Zhu, Wei Xiong, Qingyu Zhao, Youdong Zhou, Yujia Guo, Baohui Liu, Mingchang Li, Qianxue Chen, Xiaobing Jiang, Yangzhi Qi, Qingsong Ye, Gang Den. Brain-targeted ursolic acid nanoparticles for anti-ferroptosis therapy in subarachnoid hemorrhage. Journal of nanobiotechnology. vol 22. issue 1. 2024-10-19. PMID:39425081. |
subarachnoid hemorrhage (sah) is a life -threatening cerebrovascular disease, where early brain injury (ebi) stands as a primary contributor to mortality and unfavorable patient outcomes. |
2024-10-19 |
2024-10-21 |
Not clear |
| Jinshuo Yang, Qiaowei Wu, Yuchen Li, Yongzhi Zhang, Shuai Lan, Kaikun Yuan, Jiaxing Dai, Bowen Sun, Yuxiao Meng, Shancai Xu, Huaizhang Sh. BL-918 Alleviates Early Brain Injury in Rats After Subarachnoid Hemorrhage by Reducing Oxidative Stress and Promoting Mitophagy Through the ULK1/PINK1/Parkin Pathway. Free radical biology & medicine. 2024-10-05. PMID:39368518. |
oxidative stress plays a critical role in early brain injury (ebi) following subarachnoid hemorrhage (sah). |
2024-10-05 |
2024-10-08 |
rat |
| Xiaoyang Lu, Shu Yang, Qixiong Lu, Yuansheng Zhang, Zaihong Cha, Wei Huang, Tao L. Betulin ameliorates neuronal apoptosis and oxidative injury via DJ-1/Akt/Nrf2 signaling pathway after subarachnoid hemorrhage. CNS neuroscience & therapeutics. vol 30. issue 9. 2024-09-06. PMID:39238115. |
we aimed to resolve the uncertainty as to whether betulin exerted neuroprotection on early brain injury (ebi) caused by subarachnoid hemorrhage (sah), and to investigate the related molecular mechanisms. |
2024-09-06 |
2024-09-08 |
Not clear |
| Youdong Zhou, Hengyu Wang, Xinyi Zhu, Qingyu Zhao, Gang Deng, Yong Li, Qianxue Che. Improving anti-oxidant stress treatment of subarachnoid hemorrhage through self-assembled nanoparticles of oleanolic acid. Drug delivery. vol 31. issue 1. 2024-08-22. PMID:39169653. |
subarachnoid hemorrhage (sah) is a life-threatening acute hemorrhagic cerebrovascular disease, with early brain injury (ebi) being the main cause of high mortality and severe neurological dysfunction. |
2024-08-22 |
2024-08-24 |
Not clear |
| Hitoshi Kobata, Akira Sugie, Adam Tucker, Gemmalynn Sarapuddin, Hitomi Kimura, Hitoshi Takeshita, Munenori Morihara, Makiko Kawakam. High plasma D-dimer levels correlate with ictal infarction and poor outcomes in spontaneous subarachnoid hemorrhage. World neurosurgery. 2024-08-11. PMID:39128614. |
early brain injury (ebi) is the leading cause of poor outcomes in spontaneous subarachnoid hemorrhage (ssah). |
2024-08-11 |
2024-08-14 |
Not clear |
| Daniel Santana, Laura Llull, Alejandra Mosteiro, Leire Pedrosa, Gabriel Pujol, Luigi Zattera, Mariano Werner, Abraham Martín, Carles Justicia, Ángel Chamorro, Ramón Torné, Sergio Amar. Neuroaxonal Injury May Mediate the Association Between Hyperglycemia and Prognosis in Spontaneous Subarachnoid Hemorrhage. Molecular neurobiology. 2024-07-11. PMID:38992213. |
hyperglycemia during early brain injury (ebi) period after spontaneous subarachnoid hemorrhage (sah) is associated with poor outcome, but the underlying physiopathology is unknown. |
2024-07-11 |
2024-07-14 |
Not clear |
| Ming-Dong Wang, Qian-Hui Fu, Andrew Ni, Yun-Peng Yuan, Chun-Hui Li, Zhan-Xiang Wang, Hong Wan. The role of early cerebral edema and hematoma assessment in aneurysmal subarachnoid hemorrhage (a-SAH) in predicting early brain injury (EBI) and cognitive impairment: a case controlled study. International journal of surgery (London, England). vol 110. issue 6. 2024-06-27. PMID:38445521. |
the role of early cerebral edema and hematoma assessment in aneurysmal subarachnoid hemorrhage (a-sah) in predicting early brain injury (ebi) and cognitive impairment: a case controlled study. |
2024-06-27 |
2024-06-30 |
Not clear |
| Sheri Tuzi, Beate Kranawetter, Onnen Moerer, Veit Rohde, Dorothee Mielke, Vesna Malinov. Influence of cerebrospinal fluid drainage in the first days after aneurysm rupture on the severity of early brain injury following aneurysmal subarachnoid hemorrhage. Acta neurochirurgica. vol 166. issue 1. 2024-05-28. PMID:38805034. |
progressive cerebral edema with refractory intracranial hypertension (icp) requiring decompressive hemicraniectomy (dhc) is a severe manifestation of early brain injury (ebi) after aneurysmal subarachnoid hemorrhage (asah). |
2024-05-28 |
2024-06-02 |
Not clear |
| Gen Wang, Ning Li. NAD-Dependent Protein Deacetylase Sirtuin-1 Mediated Mitophagy Regulates Early Brain Injury After Subarachnoid Hemorrhage. Journal of inflammation research. vol 17. 2024-04-02. PMID:38562659. |
this study focuses on the role of sirt1 in neuroinflammation caused by early brain injury (ebi) after subarachnoid hemorrhage (sah), and explores its mechanism in mitophagy after sah. |
2024-04-02 |
2024-04-04 |
Not clear |
| Haocheng Zhang, Longbiao Xu, Yezhao He, Zeyu Zhang, Jiahao Zhang, Qian Yu, Yibo Liu, Xiaoyu Wang, Anke Zhang, Kaikai Wang, Yuanjian Fang, Sheng Che. Tat-NR2B9c attenuates oxidative stress via inhibition of PSD95-NR2B-nNOS complex after subarachnoid hemorrhage in rats. Neuropharmacology. 2024-03-23. PMID:38521229. |
oxidative stress plays important roles in the pathogenesis of early brain injury (ebi) after subarachnoid hemorrhage (sah). |
2024-03-23 |
2024-03-26 |
rat |
| Jiahui Hao, Tong Wang, Cheng Cao, Xiang Li, Haiying Li, Heng Gao, Jinquan Li, Haitao Shen, Gang Che. LPCAT3 exacerbates early brain injury and ferroptosis after subarachnoid hemorrhage in rats. Brain research. 2024-03-14. PMID:38484924. |
lysophosphatidylcholine acyltransferase 3 (lpcat3) is known to play a pivotal role in lipid metabolism, but its role in the early brain injury (ebi) following subarachnoid hemorrhage (sah) remains unclear. |
2024-03-14 |
2024-03-17 |
rat |
| Shunyan Yang, Binbin Tan, Jie Lin, Xia Wang, Congying Fu, Kaishan Wang, Jinyu Qian, Jin Liu, Jishu Xian, Liang Tan, Hua Feng, Yujie Chen, Lihua Wan. Monitoring of Perioperative Microcirculation Dysfunction by Near-Infrared Spectroscopy for Neurological Deterioration and Prognosis of Aneurysmal Subarachnoid Hemorrhage: An Observational, Longitudinal Cohort Study. Neurology and therapy. 2024-02-17. PMID:38367176. |
no evidence has established a direct causal relationship between early microcirculation disturbance after aneurysmal subarachnoid hemorrhage (asah) and neurological function prognosis, which is the key pathophysiological mechanism of early brain injury (ebi) in patients with asah. |
2024-02-17 |
2024-02-20 |
Not clear |
| Jianxiang Jin, Maosong Chen, Hongcai Wang, Shiwei Li, Lei Ma, Boding Wan. Schizandrin A attenuates early brain injury following subarachnoid hemorrhage through suppressing neuroinflammation. Molecular biology reports. vol 51. issue 1. 2024-01-29. PMID:38285214. |
early brain injury (ebi) is the vital factor in determining the outcome of subarachnoid hemorrhage (sah). |
2024-01-29 |
2024-01-31 |
human |
| Keke Zhang, Zhen Qin, Jinyan Chen, Gengyin Guo, Xiaokun Jiang, Feng Wang, Jianfeng Zhuang, Zhen Zhan. TRPV1 modulated NLRP3 inflammasome activation via calcium in experimental subarachnoid hemorrhage. Aging. vol 15. 2024-01-05. PMID:38180747. |
neuroinflammation plays a key role in early brain injury (ebi) of subarachnoid hemorrhage (sah), and nlrp3 inflammasome plays an important role in the development of neuroinflammation after sah, but the mechanism of nlrp3 inflammasome activation after sah is still unclear. |
2024-01-05 |
2024-01-07 |
Not clear |
| Zixuan Yuan, Xiaoming Zhou, Yan Zou, Bingtao Zhang, Yao Jian, Qi Wu, Shujuan Chen, Xin Zhan. Hypoxia Aggravates Neuron Ferroptosis in Early Brain Injury Following Subarachnoid Hemorrhage via NCOA4-Meditated Ferritinophagy. Antioxidants (Basel, Switzerland). vol 12. issue 12. 2023-12-23. PMID:38136217. |
the occurrence of early brain injury (ebi) significantly contributes to the unfavorable prognosis observed in patients with subarachnoid hemorrhage (sah). |
2023-12-23 |
2023-12-25 |
Not clear |
| Hui Liu, Dan Guo, Jiao Wang, Wenxu Zhang, Zechao Zhu, Kunyuan Zhu, Shijun Bi, Pengyu Pan, Guobiao Lian. Aloe-emodin from Sanhua Decoction inhibits neuroinflammation by regulating microglia polarization after subarachnoid hemorrhage. Journal of ethnopharmacology. 2023-12-20. PMID:38122912. |
subarachnoid hemorrhage (sah) triggers a cascade of events that lead to early brain injury (ebi), which contributes to poor outcomes and appears within 3 days after sah initiation. |
2023-12-20 |
2023-12-23 |
Not clear |
| Liuqing Sheng, Xiaolong Yao, Jianfeng Ye, Zhizhong Wang, Yinchun Chen, Jun Li, Mingchang L. Eriocitrin Alleviates Inflammation and Oxidative Stress in Subarachnoid Hemorrhage by Regulating DUSP14. Discovery medicine. vol 35. issue 179. 2023-12-07. PMID:38058079. |
inflammation and oxidative stress (os) are major causes of aneurysmal subarachnoid hemorrhage (asah)-induced early brain injury (ebi). |
2023-12-07 |
2023-12-10 |
Not clear |
| Weihan Wang, Cong Pang, Jiaxing Zhang, Lei Peng, Xianghua Zhang, Lin Shi, Hao Zhan. Takinib inhibits microglial M1 polarization and oxidative damage after subarachnoid hemorrhage by targeting TAK1-dependent NLRP3 inflammasome signaling pathway. Frontiers in immunology. vol 14. 2023-11-30. PMID:38035075. |
however, the effects of takinib on early brain injury (ebi) after subarachnoid hemorrhage (sah) and the underlying molecular mechanisms remain unknown. |
2023-11-30 |
2023-12-10 |
Not clear |
| Chengli Liu, Kun Yao, Qi Tian, Yujia Guo, Guijun Wang, Peibang He, Jianfeng Wang, Jian Wang, Zhan Zhang, Mingchang L. CXCR4-BTK axis mediate pyroptosis and lipid peroxidation in early brain injury after subarachnoid hemorrhage via NLRP3 inflammasome and NF-κB pathway. Redox biology. vol 68. 2023-11-18. PMID:37979447. |
this study aims to explore the effect of cxcr4 and btk on neuroinflammation in the pathogenesis of early brain injury (ebi) after subarachnoid hemorrhage (sah). |
2023-11-18 |
2023-11-20 |
mouse |
| Shengjie Tang, Niansheng Lai, Liang X. Neuronal pyroptosis mediated by STAT3 in early brain injury after subarachnoid hemorrhage. Brain research. 2023-11-10. PMID:37949309. |
neuroinflammation induced by early brain injury (ebi) seriously affects the prognosis of patients after subarachnoid hemorrhage (sah). |
2023-11-10 |
2023-11-20 |
mouse |