| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiao Ran, Tingting Xu, Hang Ruan, Xiaochuan Wang, Qin Zhan. Tissue Kallikrein Supplementation in Ischemic Phase Protects the Neurovascular Unit and Attenuates Reperfusion-Induced Injury in Ischemic Stroke. Pharmacological research. 2024-09-30. PMID:39349214. |
here, we established a causal link between lower baseline tk levels and an increased risk of stroke through a retrospective, multicenter cohort study involving 2,115 initially non-stroke subjects monitored for 5 years. |
2024-09-30 |
2024-10-03 |
human |
| Qin Zhang, Juan Tan, Li Wan, Chao Chen, Bin Wu, Xijian Ke, Rongxue Wu, Xiao Ra. Increase in Blood-Brain Barrier Permeability is Modulated by Tissue Kallikrein via Activation of Bradykinin B1 and B2 Receptor-Mediated Signaling. Journal of inflammation research. vol 14. 2021-09-14. PMID:34511968. |
although tissue kallikrein (tk) has used in the treatment of stroke in china, the role of tk in modulating bbb permeability is not clear. |
2021-09-14 |
2023-08-13 |
Not clear |
| Jia, Burggre. Developmental changes in chemoreceptive control of gill ventilation in larval bullfrogs (Rana catesbeiana). I. Reflex ventilatory responses to ambient hyperoxia, hypoxia and NaCN The Journal of experimental biology. vol 200. issue Pt 16. 2019-11-20. PMID:9320145. |
reflex ventilatory responses to ambient hyperoxia, hypoxia and nacn the time course of reflex changes in gill ventilation frequency, buccal pressure, branchial stroke volume and minute ventilation caused by a step-wise change in po2 of inspired water and by the introduction of nacn into the inspired water was measured in unanesthetized larval bullfrogs (rana catesbeiana) at developmental stages tk vvii, ixxi and xviixix. |
2019-11-20 |
2023-08-12 |
Not clear |
| Xiao Ran, Qin Zhang, Dao Wen Wan. Tissue Kallikrein Activity, Detected by a Novel Method, May Be a Predictor of Recurrent Stroke: A Case-Control Study. Disease markers. vol 2015. 2016-07-26. PMID:26451066. |
tissue kallikrein (tk) protein content in plasma has been shown to be negatively associated with both incident and recurrent strokes. |
2016-07-26 |
2023-08-13 |
Not clear |
| Xiao Ran, Qin Zhang, Dao Wen Wan. Tissue Kallikrein Activity, Detected by a Novel Method, May Be a Predictor of Recurrent Stroke: A Case-Control Study. Disease markers. vol 2015. 2016-07-26. PMID:26451066. |
the aims of this study were to develop a novel method for detecting tk activity and to investigate its association with event-free survival over 5 years in chinese first-ever stroke patients. |
2016-07-26 |
2023-08-13 |
Not clear |
| Qin Zhang, Hu Ding, Jiangtao Yan, Wei Wang, Aiqun Ma, Zhiming Zhu, Katherine Cianflone, Frank B Hu, Rutai Hui, Dao Wen Wan. Plasma tissue kallikrein level is negatively associated with incident and recurrent stroke: a multicenter case-control study in China. Annals of neurology. vol 70. issue 2. 2011-09-30. PMID:21823154. |
in this study, we investigated the association of tk levels with event-free survival over 5 years in chinese first-ever stroke patients. |
2011-09-30 |
2023-08-12 |
Not clear |
| Heike Beck, Sabine Raab, Ekaterini Copanaki, Matthias Heil, Alexander Scholz, Masabumi Shibuya, Thomas Deller, Marcia Machein, Karl H Plat. VEGFR-1 signaling regulates the homing of bone marrow-derived cells in a mouse stroke model. Journal of neuropathology and experimental neurology. vol 69. issue 2. 2010-03-15. PMID:20084017. |
because macrophages are recruited to sites of cerebral ischemic infarcts, we hypothesized that lack of vegfr-1 tk in bone marrow(bm) cells would affect the outcome in an experimental stroke model. |
2010-03-15 |
2023-08-12 |
mouse |