All Relations between Schizophrenia and prefrontal cortex

Publication Sentence Publish Date Extraction Date Species
Sihang Yu, Shuai Wang, Hang Su. Effects of repetitive transcranial magnetic stimulation on inhibitory control in first-episode schizophrenia: behavioral and neural mechanisms. Frontiers in psychiatry. vol 15. 2024-11-19. PMID:39559278. repetitive transcranial magnetic stimulation (rtms) targeting the dorsolateral prefrontal cortex (dlpfc) may help improve inhibitory control, but its specific effects in schizophrenia remain uncertain. 2024-11-19 2024-11-22 Not clear
Deying Song, Daniel W Chung, G Bard Ermentrou. Mean-field analysis of synaptic alterations underlying deficient cortical gamma oscillations in schizophrenia. Journal of computational neuroscience. 2024-11-08. PMID:39514045. deficient gamma oscillations in the prefrontal cortex (pfc) of individuals with schizophrenia (sz) are proposed to arise from alterations in the excitatory drive to fast-spiking interneurons (e 2024-11-08 2024-11-16 Not clear
Anna S Huang, Ralf D Wimmer, Norman H Lam, Bin A Wang, Sahil Suresh, Maxwell J Roeske, Burkhard Pleger, Michael M Halassa, Neil D Woodwar. A prefrontal thalamocortical readout for conflict-related executive dysfunction in schizophrenia. Cell reports. Medicine. 2024-11-08. PMID:39515319. dorsolateral prefrontal cortex (dlpfc) deficits have been linked to schizophrenia executive dysfunction, but mechanistic details critical for treatment development remain unclear. 2024-11-08 2024-11-16 human
Takeshi Okuda, Sohei Kimoto, Rika Kawabata, Yufan Bian, Makoto Tsubomoto, Kazuya Okamura, John F Enwright, Mitsuru Kikuchi, David A Lewis, Takanori Hashimot. Alterations in inhibitory neuron subtype-selective transcripts in the prefrontal cortex: comparisons across schizophrenia and mood disorders. Psychological medicine. 2024-10-31. PMID:39478366. alterations in inhibitory neuron subtype-selective transcripts in the prefrontal cortex: comparisons across schizophrenia and mood disorders. 2024-10-31 2024-11-02 Not clear
Jiunn-Kae Wang, Prangya Parimita Sahu, Hsiao-Lun Ku, Yu-Hui Lo, Ying-Ru Chen, Che-Yin Lin, Philip Tsen. Enhancing visual working memory in schizophrenia: effects of frontoparietal theta tACS in low-performing patients. Schizophrenia (Heidelberg, Germany). vol 10. issue 1. 2024-10-27. PMID:39461954. additionally, we took advantage of this tagging feature and applied 6 hz transcranial alternating current stimulation (tacs) over the right dorsolateral prefrontal cortex (dlpfc) and right posterior parietal cortex (ppc)-which has previously been shown to enhance vwm in low-performing healthy individuals-to examine whether tacs would improve a specific stage or all stages of vwm processing in schizophrenia. 2024-10-27 2024-10-29 Not clear
Hannah Hughes, Lillian J Brady, Kirsten E Schoonove. GABAergic dysfunction in postmortem dorsolateral prefrontal cortex: implications for cognitive deficits in schizophrenia and affective disorders. Frontiers in cellular neuroscience. vol 18. 2024-10-09. PMID:39381500. gabaergic dysfunction in postmortem dorsolateral prefrontal cortex: implications for cognitive deficits in schizophrenia and affective disorders. 2024-10-09 2024-10-11 Not clear
Christin Schifani, Colin Hawco, Zafiris J Daskalakis, Tarek K Rajji, Benoit H Mulsant, Vinh Tan, Erin W Dickie, Iska Moxon-Emre, Daniel M Blumberger, Aristotle N Voinesko. Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment Reduces Variability in Brain Function in Schizophrenia: Data From a Double-Blind, Randomized, Sham-Controlled Trial. Schizophrenia bulletin. 2024-10-07. PMID:39373168. we perform a secondary analysis using data from a double-blind randomized controlled 4-week trial of 20 hz active versus sham rtms to dorsolateral prefrontal cortex (dlpfc) during a working memory task in participants with schizophrenia. 2024-10-07 2024-10-09 human
Ta-Chuan Yeh, Yen-Yue Lin, Nian-Sheng Tzeng, Yu-Chen Kao, Yong-An Chung, Chuan-Chia Chang, Hsu-Wei Fang, Hsin-An Chan. Effects of online high-definition transcranial direct current stimulation over left dorsolateral prefrontal cortex on predominant negative symptoms and EEG functional connectivity in patients with schizophrenia: a randomized, double-blind, controlled trial. Psychiatry and clinical neurosciences. 2024-09-25. PMID:39317963. effects of online high-definition transcranial direct current stimulation over left dorsolateral prefrontal cortex on predominant negative symptoms and eeg functional connectivity in patients with schizophrenia: a randomized, double-blind, controlled trial. 2024-09-25 2024-09-27 Not clear
Dylan J Kiltschewskij, William R Reay, Murray J Cairn. Schizophrenia is associated with altered DNA methylation variance. Molecular psychiatry. 2024-09-13. PMID:39271751. these blood-derived vmps were found to be overrepresented in genes previously associated with schizophrenia and amongst brain-enriched genes, with evidence of concordant changes at vmps in the cerebellum, hippocampus, prefrontal cortex, or striatum. 2024-09-13 2024-09-16 Not clear
Jianjun Weng, Xiaoli Zhu, Yu Ouyang, Yanqing Liu, Hongmei Lu, Jiakui Yao, Bo Pa. Identification of Immune-Related Biomarkers of Schizophrenia in the Central Nervous System Using Bioinformatic Methods and Machine Learning Algorithms. Molecular neurobiology. 2024-09-07. PMID:39243324. in this study, five datasets of schizophrenia post-mortem prefrontal cortex samples were downloaded from the geo database and then merged and de-batched for the analyses of differentially expressed genes (degs) and weighted gene co-expression network analysis (wgcna). 2024-09-07 2024-09-10 human
Ningping Feng, Ajeet Mandal, Ananya Jambhale, Pranav Narnur, Gang Chen, Nirmala Akula, Robin Kramer, Bhaskar Kolachana, Qing Xu, Francis J McMahon, Barbara K Lipska, Pavan K Auluck, Stefano Marenc. Schizophrenia risk-associated SNPs affect expression of microRNA 137 host gene: a postmortem study. Human molecular genetics. 2024-09-06. PMID:39239979. to elucidate the association of schizophrenia risk-associated snps in this genomic region, we examined the expression of both mature and immature transcripts of the mir-137 host gene (mir137hg) in the dorsolateral prefrontal cortex (dlpfc) and subgenual anterior cingulate cortex (sgacc) of postmortem brain samples of donors with schizophrenia and psychiatrically-unaffected controls using qpcr and rna-seq approaches. 2024-09-06 2024-09-08 Not clear
Masaya Yanagi, Mamoru Hashimot. Dysfunctional Parvalbumin Neurons in Schizophrenia and the Pathway to the Clinical Application of Kv3 Channel Modulators. International journal of molecular sciences. vol 25. issue 16. 2024-08-29. PMID:39201380. decreased kv3.1 levels have been observed in the prefrontal cortex of patients with schizophrenia, prompting the investigation of kv3 channel modulators for the treatment of schizophrenia. 2024-08-29 2024-09-01 Not clear
Feng-Ling Xu, Bao-Jie Wan. Hsa-miR-874-3p Reduces Endogenous Expression of RGS4-1 Isoform In Vitro. Genes. vol 15. issue 8. 2024-08-29. PMID:39202417. the level of the regulator of g-protein signaling 4-1 (rgs4-1) isoform, the longest rgs4 isoform, is significantly reduced in the dorsolateral prefrontal cortex (dlpfc) of people with schizophrenia. 2024-08-29 2024-09-04 Not clear
Wenpeng Hou, Xiangqin Qin, Hang Li, Qi Wang, Yushen Ding, Xiongying Chen, Ru Wang, Fang Dong, Qijing Bo, Xianbin Li, Fuchun Zhou, Chuanyue Wan. Interaction between BDNF Val66Met polymorphism and mismatch negativity for working memory capacity in schizophrenia. Schizophrenia (Heidelberg, Germany). vol 10. issue 1. 2024-08-22. PMID:39174571. the trial assessed the efficacy of transcranial direct current stimulation for enhancing working memory in clinically stable schizophrenia patients, who were randomly divided into three groups: dorsolateral prefrontal cortex stimulation, posterior parietal cortex stimulation, and sham stimulation groups. 2024-08-22 2024-08-25 Not clear
Amir-Homayun Hallajian, Kiomars Sharifi, Reza Rostami, Fahimeh Saeed, Shirin Mokarian Rajabi, Negin Zangenehnia, Zahra Amini, Zahra Askari, Fidel Vila-Rodriguez, Mohammad Ali Salehineja. Neurocognitive effects of 3 mA prefrontal electrical stimulation in schizophrenia: A randomized sham-controlled tDCS-fMRI study protocol. PloS one. vol 19. issue 8. 2024-08-16. PMID:39150917. schizophrenia (scz) is characterized by cognitive deficits that are linked to prefrontal cortex dysfunction. 2024-08-16 2024-08-19 Not clear
Claire E Tume, Sophie L Chick, Peter A Holmans, Elliott Rees, Michael C O'Donovan, Darren Cameron, Nicholas J Bra. Genetic Implication of Specific Glutamatergic Neurons of the Prefrontal Cortex in the Pathophysiology of Schizophrenia. Biological psychiatry global open science. vol 4. issue 5. 2024-08-05. PMID:39099730. genetic implication of specific glutamatergic neurons of the prefrontal cortex in the pathophysiology of schizophrenia. 2024-08-05 2024-08-07 human
Claire E Tume, Sophie L Chick, Peter A Holmans, Elliott Rees, Michael C O'Donovan, Darren Cameron, Nicholas J Bra. Genetic Implication of Specific Glutamatergic Neurons of the Prefrontal Cortex in the Pathophysiology of Schizophrenia. Biological psychiatry global open science. vol 4. issue 5. 2024-08-05. PMID:39099730. the prefrontal cortex (pfc) has been strongly implicated in the pathophysiology of schizophrenia. 2024-08-05 2024-08-07 human
Claire E Tume, Sophie L Chick, Peter A Holmans, Elliott Rees, Michael C O'Donovan, Darren Cameron, Nicholas J Bra. Genetic Implication of Specific Glutamatergic Neurons of the Prefrontal Cortex in the Pathophysiology of Schizophrenia. Biological psychiatry global open science. vol 4. issue 5. 2024-08-05. PMID:39099730. here, we combined high-resolution single-nuclei rna sequencing data from the human pfc with large-scale genomic data for schizophrenia to identify constituent cell populations likely to mediate genetic liability to the disorder. 2024-08-05 2024-08-07 human
A Dorsolateral Prefrontal Cortex Joint Neuron-Astrocyte Program Is Decreased in Schizophrenia and Aging. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 30. issue 4. 2024-08-05. PMID:39101258. a dorsolateral prefrontal cortex joint neuron-astrocyte program is decreased in schizophrenia and aging. 2024-08-05 2024-08-07 Not clear
N S Kolomeets, N A Uranov. Deficit of satellite oligodendrocytes of neurons in the rostral part of the head of the caudate nucleus in schizophrenia. European archives of psychiatry and clinical neuroscience. 2024-07-29. PMID:39073446. we previously reported a deficiency of myelinating oligodendrocytes (ol), oligodendrocyte progenitors (op) and satellite oligodendrocytes of neurons (sat-ol) in the prefrontal cortex and the inferior parietal cortex - cortical hubs of the frontoparietal cognitive network and default mode network (dmn) altered in schizophrenia. 2024-07-29 2024-08-02 Not clear