All Relations between Schizophrenia and middle frontal gyrus

Publication Sentence Publish Date Extraction Date Species
Yuhao Yao, Shufang Zhang, Boyao Wang, Xiaoyong Lin, Gaofeng Zhao, Hong Deng, Ying Che. Neural dysfunction underlying working memory processing at different stages of the illness course in schizophrenia: a comparative meta-analysis. Cerebral cortex (New York, N.Y. : 1991). vol 34. issue 7. 2024-07-03. PMID:38960703. the clinical high risk and first-episode psychosis groups exhibited overlapping hypoactivation in the right inferior parietal lobule, right middle frontal gyrus, and left superior parietal lobule, indicating key lesion sites in the early phase of schizophrenia. 2024-07-03 2024-07-10 Not clear
Xun Yang, Yuan Song, Yuhan Zou, Yilin Li, Jianguang Zen. Neural correlates of prediction error in patients with schizophrenia: evidence from an fMRI meta-analysis. Cerebral cortex (New York, N.Y. : 1991). 2023-12-07. PMID:38061699. our meta-analysis showed that, relative to healthy controls, schizophrenia patients showed increased activity in the precentral gyrus and middle frontal gyrus and reduced activity in the mesolimbic circuit, including the striatum, thalamus, amygdala, hippocampus, anterior cingulate cortex, insula, superior temporal gyrus, and cerebellum, when processing prediction errors. 2023-12-07 2023-12-17 Not clear
Huaigui Liu, Wei Li, Nana Liu, Jie Tang, Lixin Sun, Jiayuan Xu, Yuan Ji, Yingying Xie, Hao Ding, Zhaoxiang Ye, Chunshui Yu, Wen Qi. Structural covariances of prefrontal subregions selectively associate with dopamine-related gene coexpression and schizophrenia. Cerebral cortex (New York, N.Y. : 1991). 2023-03-19. PMID:36935097. moreover, based on a schizophrenia postmortem expression dataset, we found that the da genes coexpression of schizophrenia was significantly reduced between the middle frontal gyrus and hippocampus, in which 21 da genes showed significantly unsynchronized expression changes, and the 21 genes' brain expression were enriched in brain activity invoked by working memory, reward, speech production, and episodic memory. 2023-03-19 2023-08-14 human
Paris Alexandros Lalousis, Aanya Malaviya, Rachel Upthegrove, Kareen Heinze, Ana Diukova, Dorothee Auer, Peter Liddle, Pavan Mallikarju. Trait related aberrant connectivity in clinically stable patients with schizophrenia: A seed based resting state fMRI study. Brain imaging and behavior. 2022-10-14. PMID:36241961. compared with healthy controls, patients with schizophrenia showed increased connectivity between the left lingual gyrus and the middle frontal gyrus, and the cingulate cortex. 2022-10-14 2023-08-14 Not clear
Lisa Rauer, Sarah Trost, Aleksandra Petrovic, Oliver Grube. Cortical activation abnormalities in bipolar and schizophrenia patients in a combined oddball-incongruence paradigm. European archives of psychiatry and clinical neuroscience. vol 271. issue 8. 2021-11-05. PMID:32710172. furthermore, bipolar patients revealed diagnosis-specific hyperactivation in the left middle frontal gyrus, precentral gyrus, anteroventral prefrontal cortex and orbitofrontal cortex regions compared to schizophrenia patients and healthy individuals. 2021-11-05 2023-08-13 Not clear
Xu Li, Zheng-Hui Yi, Qin-Yu Lv, Min-Yi Chu, Hui-Xin Hu, Jin-Hong Wang, Jian-Ye Zhang, Eric E F Cheung, Raymond C K Cha. Clinical utility of the dual n-back task in schizophrenia: A functional imaging approach. Psychiatry research. Neuroimaging. vol 284. 2020-02-06. PMID:30658243. moreover, hypoactivation was observed at the right middle frontal gyrus and the posterior parietal regions in schizophrenia participants compared with healthy controls. 2020-02-06 2023-08-13 human
Feng Liu, Hongjun Tian, Jie Li, Shen Li, Chuanjun Zhu. Altered voxel-wise gray matter structural brain networks in schizophrenia: Association with brain genetic expression pattern. Brain imaging and behavior. vol 13. issue 2. 2019-08-12. PMID:29728906. compared with healthy controls, the patients with schizophrenia showed significantly increased structural covariance strength (scs) in the right orbital part of superior frontal gyrus and bilateral middle frontal gyrus, while decreased scs in the bilateral superior temporal gyrus and precuneus. 2019-08-12 2023-08-13 human
Andrea Cantisani, Katharina Stegmayer, Andrea Federspiel, Stephan Bohlhalter, Roland Wiest, Sebastian Walthe. Blood perfusion in left inferior and middle frontal gyrus predicts communication skills in schizophrenia. Psychiatry research. Neuroimaging. vol 274. 2019-03-21. PMID:29456122. blood perfusion in left inferior and middle frontal gyrus predicts communication skills in schizophrenia. 2019-03-21 2023-08-13 Not clear
Andrea Cantisani, Katharina Stegmayer, Andrea Federspiel, Stephan Bohlhalter, Roland Wiest, Sebastian Walthe. Blood perfusion in left inferior and middle frontal gyrus predicts communication skills in schizophrenia. Psychiatry research. Neuroimaging. vol 274. 2019-03-21. PMID:29456122. a negative linear association was noted between fc and rcbf in the left inferior and middle frontal gyrus, areas involved in language processing, suggesting a potential relationship between cerebral perfusion and prospective fc in schizophrenia. 2019-03-21 2023-08-13 Not clear
Toshiyuki Ohtani, Elisabetta Del Re, James J Levitt, Margaret Niznikiewicz, Jun Konishi, Takeshi Asami, Toshiro Kawashima, Tomohide Roppongi, Paul G Nestor, Martha E Shenton, Dean F Salisbury, Robert W McCarle. Progressive symptom-associated prefrontal volume loss occurs in first-episode schizophrenia but not in affective psychosis. Brain structure & function. vol 223. issue 6. 2019-02-28. PMID:29671056. the object of this study was to determine whether first-episode schizophrenia (fesz) and first-episode affective psychosis (feaff) patients show initial and progressive pfc gmv reduction in bilateral frontal pole, superior frontal gyrus (sfg), middle frontal gyrus (mfg), and inferior frontal gyrus (ifg) and examine their symptom associations. 2019-02-28 2023-08-13 human
Hans C van Mierlo, Catharina G K Wichers, Yujie He, Marjolein A M Sneeboer, Timothy R D J Radstake, René S Kahn, Jasper C A Broen, Lot D de Witt. Telomere quantification in frontal and temporal brain tissue of patients with schizophrenia. Journal of psychiatric research. vol 95. 2018-06-07. PMID:28910708. in this study we measured telomere length, a marker for cell senescence, in gray and white matter brain tissue from the medial frontal gyrus (mfg) and superior temporal gyrus (stg) of 9 patients with schizophrenia and 11 controls. 2018-06-07 2023-08-13 Not clear
Andrew B Poppe, Deanna M Barch, Cameron S Carter, James M Gold, John Daniel Ragland, Steven M Silverstein, Angus W MacDonal. Reduced Frontoparietal Activity in Schizophrenia Is Linked to a Specific Deficit in Goal Maintenance: A Multisite Functional Imaging Study. Schizophrenia bulletin. vol 42. issue 5. 2017-07-19. PMID:27060129. patients with schizophrenia (sz) previously demonstrated specific deficits in an executive function known as goal maintenance, associated with reduced middle frontal gyrus (mfg) activity. 2017-07-19 2023-08-13 Not clear
Raymond C K Chan, Jia Huang, Qing Zhao, Ya Wang, Yun-yao Lai, Nan Hong, David H K Shum, Eric F C Cheung, Xin Yu, Paola Dazza. Prefrontal cortex connectivity dysfunction in performing the Fist-Edge-Palm task in patients with first-episode schizophrenia and non-psychotic first-degree relatives. NeuroImage. Clinical. vol 9. 2016-09-06. PMID:26594623. in the contrast of fep vs. pt, patients with schizophrenia did not show areas of significant activation, while relatives and healthy controls showed significant activation of the left middle frontal gyrus. 2016-09-06 2023-08-13 human
Alex Kopelowicz, Roberto Zarate, Charles J Wallace, Robert Paul Liberman, Steven R Lopez, Jim Mint. Using the theory of planned behavior to improve treatment adherence in Mexican Americans with schizophrenia. Journal of consulting and clinical psychology. vol 83. issue 5. 2016-05-23. PMID:26030760. a novel multifamily group (mfg) intervention, informed by the theory of planned behavior (tpb), demonstrated efficacy in increasing medication adherence and decreasing rehospitalizations in schizophrenia patients. 2016-05-23 2023-08-13 Not clear
Jiajia Zhu, Chuanjun Zhuo, Wen Qin, Yongjie Xu, Lixue Xu, Xingyun Liu, Chunshui Y. Altered resting-state cerebral blood flow and its connectivity in schizophrenia. Journal of psychiatric research. vol 63. 2016-03-07. PMID:25812945. compared with the healthy controls, the schizophrenia patients exhibited increased cbf in the bilateral inferior temporal gyri, thalami and putamen and decreased cbf in the left insula and middle frontal gyrus and the bilateral anterior cingulate cortices and middle occipital gyri. 2016-03-07 2023-08-13 human
Mario Quarantelli, Olga Palladino, Anna Prinster, Vittorio Schiavone, Barbara Carotenuto, Arturo Brunetti, Angela Marsili, Margherita Casiello, Giovanni Muscettola, Marco Salvatore, Andrea de Bartolomei. Patients with poor response to antipsychotics have a more severe pattern of frontal atrophy: a voxel-based morphometry study of treatment resistance in schizophrenia. BioMed research international. vol 2014. 2015-11-02. PMID:25157354. post hoc direct comparison between the two schizophrenia subgroups demonstrated significantly reduced grey matter volumes in middle frontal gyrus bilaterally, in the dorsolateral aspects of left superior frontal gyrus extending into postcentral gyrus and in the right medial temporal cortex. 2015-11-02 2023-08-13 human
Karuna Subramaniam, Tracy L Luks, Coleman Garrett, Cleo Chung, Melissa Fisher, Srikantan Nagarajan, Sophia Vinogrado. Intensive cognitive training in schizophrenia enhances working memory and associated prefrontal cortical efficiency in a manner that drives long-term functional gains. NeuroImage. vol 99. 2015-04-13. PMID:24867353. we investigated whether intensive computerized cognitive training in schizophrenia could improve working memory performance and increase signal efficiency of associated middle frontal gyri (mfg) circuits in a functionally meaningful manner. 2015-04-13 2023-08-13 human
Karuna Subramaniam, Tracy L Luks, Coleman Garrett, Cleo Chung, Melissa Fisher, Srikantan Nagarajan, Sophia Vinogrado. Intensive cognitive training in schizophrenia enhances working memory and associated prefrontal cortical efficiency in a manner that drives long-term functional gains. NeuroImage. vol 99. 2015-04-13. PMID:24867353. schizophrenia participants showed impaired working memory, hypoactivation in left mfg, and no correlation between bilateral mfg signal and task performance. 2015-04-13 2023-08-13 human
Karuna Subramaniam, Tracy L Luks, Coleman Garrett, Cleo Chung, Melissa Fisher, Srikantan Nagarajan, Sophia Vinogrado. Intensive cognitive training in schizophrenia enhances working memory and associated prefrontal cortical efficiency in a manner that drives long-term functional gains. NeuroImage. vol 99. 2015-04-13. PMID:24867353. after training, schizophrenia participants improved their 2-back working memory performance and showed increased activation in left mfg. 2015-04-13 2023-08-13 human
Karuna Subramaniam, Tracy L Luks, Coleman Garrett, Cleo Chung, Melissa Fisher, Srikantan Nagarajan, Sophia Vinogrado. Intensive cognitive training in schizophrenia enhances working memory and associated prefrontal cortical efficiency in a manner that drives long-term functional gains. NeuroImage. vol 99. 2015-04-13. PMID:24867353. working memory impairments in schizophrenia and its underlying neural correlates in mfg can be improved by intensive computerized cognitive training; these improvements generalize beyond the trained task and are associated with enduring effects on cognition and functioning 6 months after the intervention. 2015-04-13 2023-08-13 human