| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Per Thunberg, David Fresnais, Paul Hamilton, Susanne Bejerot, Mats B Humbl. Immunomodulatory treatment may change functional and structural brain imaging in severe mental disorders. Brain, behavior, & immunity - health. vol 41. 2024-10-01. PMID:39350952. |
there were significant interactions (diagnosis x time) in connectivity between right posterior insula and two clusters encompassing basal ganglia and anterior frontal pole, and between left anterior insula and a cluster in basal ganglia, where connectivity decreased in ocd and increased in schizophrenia. |
2024-10-01 |
2024-10-03 |
Not clear |
| Megan Snelleksz, Brian Dea. Higher levels of AKT-interacting protein in the frontal pole from people with schizophrenia are limited to a sub-group who have a marked deficit in cortical muscarinic M1 receptors. Psychiatry research. vol 341. 2024-09-05. PMID:39236366. |
higher levels of akt-interacting protein in the frontal pole from people with schizophrenia are limited to a sub-group who have a marked deficit in cortical muscarinic m1 receptors. |
2024-09-05 |
2024-09-08 |
Not clear |
| Èlia Vila, Raquel Pinacho, Roger Prades, Teresa Tarragó, Elena Castro, Eva Munarriz-Cuezva, J Javier Meana, Ania Eugui-Anta, Mònica Roldan, América Vera-Montecinos, Belén Ramo. Inhibition of Prolyl Oligopeptidase Restores Prohibitin 2 Levels in Psychosis Models: Relationship to Cognitive Deficits in Schizophrenia. International journal of molecular sciences. vol 24. issue 7. 2023-04-13. PMID:37046989. |
to shed light on this, we measured the phb2 levels by immunoblot in a postmortem dorsolateral prefrontal cortex (dlpfc) of schizophrenia subjects, in the frontal pole of mice treated with the nmdar antagonists phencyclidine and dizocilpine, and in rat cortical astrocytes and neurons treated with dizocilpine. |
2023-04-13 |
2023-08-14 |
mouse |
| Adriana M Medina, Megan Hastings Hagenauer, David M Krolewski, Evan Hughes, Liam Cannon Thew Forrester, David M Walsh, Maria Waselus, Evelyn Richardson, Cortney A Turner, P Adolfo Sequeira, Preston M Cartagena, Robert C Thompson, Marquis P Vawter, Blynn G Bunney, Richard M Myers, Jack D Barchas, Francis S Lee, Alan F Schatzberg, William E Bunney, Huda Akil, Stanley J Watso. Neurotransmission-related gene expression in the frontal pole is altered in subjects with bipolar disorder and schizophrenia. Translational psychiatry. vol 13. issue 1. 2023-04-08. PMID:37031222. |
neurotransmission-related gene expression in the frontal pole is altered in subjects with bipolar disorder and schizophrenia. |
2023-04-08 |
2023-08-14 |
human |
| Jacob Levman, Priya Kabaria, Masahito Nangaku, Emi Takahash. Morphological Abnormalities in Early-Onset Schizophrenia Revealed by Structural Magnetic Resonance Imaging. Biology. vol 12. issue 3. 2023-03-29. PMID:36979045. |
results demonstrate statistically significant abnormal presentation of the curvature of select brain regions in early-onset schizophrenia with large effect sizes, inclusive of the pars orbitalis, pars triangularis, posterior cingulate cortex, frontal pole, orbital gyrus, lateral orbitofrontal gyrus, inferior occipital gyrus, as well as in medial occipito-temporal, lingual, and insular sulci. |
2023-03-29 |
2023-08-14 |
Not clear |
| Megan Snelleksz, Susan L Rossell, Andrew Gibbons, Jess Nithianantharajah, Brian Dea. Evidence that the frontal pole has a significant role in the pathophysiology of schizophrenia. Psychiatry research. vol 317. 2022-09-29. PMID:36174274. |
evidence that the frontal pole has a significant role in the pathophysiology of schizophrenia. |
2022-09-29 |
2023-08-14 |
Not clear |
| Megan Snelleksz, Susan L Rossell, Andrew Gibbons, Jess Nithianantharajah, Brian Dea. Evidence that the frontal pole has a significant role in the pathophysiology of schizophrenia. Psychiatry research. vol 317. 2022-09-29. PMID:36174274. |
these data argued that the frontal pole is significantly affected by the pathophysiology of schizophrenia. |
2022-09-29 |
2023-08-14 |
Not clear |
| Megan Snelleksz, Susan L Rossell, Andrew Gibbons, Jess Nithianantharajah, Brian Dea. Evidence that the frontal pole has a significant role in the pathophysiology of schizophrenia. Psychiatry research. vol 317. 2022-09-29. PMID:36174274. |
we detail the many structural, cellular and molecular abnormalities in the frontal pole from people with schizophrenia and present findings that argue the symptoms of schizophrenia are closely linked to dysfunction in this critical brain region. |
2022-09-29 |
2023-08-14 |
Not clear |
| Megan Snelleksz, Susan L Rossell, Andrew Gibbons, Jess Nithianantharajah, Brian Dea. Evidence that the frontal pole has a significant role in the pathophysiology of schizophrenia. Psychiatry research. vol 317. 2022-09-29. PMID:36174274. |
in this review we summarise the growing body of evidence to support the hypothesis that a dysfunctional frontal pole, due at least in part to its widespread effects on brain function, is making an important contribution to the pathophysiology of schizophrenia. |
2022-09-29 |
2023-08-14 |
Not clear |
| Megan Snelleksz, Susan L Rossell, Andrew Gibbons, Jess Nithianantharajah, Brian Dea. Evidence that the frontal pole has a significant role in the pathophysiology of schizophrenia. Psychiatry research. vol 317. 2022-09-29. PMID:36174274. |
recently published data suggested there are many more changes in gene expression in the frontal pole (brodmann's area (ba) 10) compared to the dorsolateral prefrontal cortex (ba 9) and the anterior cingulate cortex (ba 33) from patients with schizophrenia. |
2022-09-29 |
2023-08-14 |
Not clear |
| Akash Prasannakumar, Vittal Korann, Arpitha Jacob, Rose Dawn Bharath, Vijay Kumar, Shivarama Varambally, Ganesan Venkatasubramanian, Naren P Ra. Relation between frontal pole volumes and cognitive insight in Schizophrenia. Asian journal of psychiatry. vol 76. 2022-07-30. PMID:35907267. |
relation between frontal pole volumes and cognitive insight in schizophrenia. |
2022-07-30 |
2023-08-14 |
Not clear |
| Akash Prasannakumar, Vittal Korann, Arpitha Jacob, Rose Dawn Bharath, Vijay Kumar, Shivarama Varambally, Ganesan Venkatasubramanian, Naren P Ra. Relation between frontal pole volumes and cognitive insight in Schizophrenia. Asian journal of psychiatry. vol 76. 2022-07-30. PMID:35907267. |
the frontal pole (fp) is implicated in metacognitive function in healthy individuals, but its role is not well examined in schizophrenia. |
2022-07-30 |
2023-08-14 |
Not clear |
| H K Luckhoff, L Asmal, F Scheffler, L Phahladira, R Smit, L van den Heuvel, J P Fouche, S Seedat, R Emsley, S du Plessi. Associations between BMI and brain structures involved in food intake regulation in first-episode schizophrenia spectrum disorders and healthy controls. Journal of psychiatric research. vol 152. 2022-06-26. PMID:35753245. |
for the individual rois, schizophrenia diagnosis predicted thinner left and right frontal pole and right lateral ofc thickness, and increased bmi predicted thinner left and right caudal acc thickness. |
2022-06-26 |
2023-08-14 |
Not clear |
| Megan Snelleksz, Brian Dea. Lower levels of tubulin alpha 1b in the frontal pole in schizophrenia supports a role for changed cytoskeletal dynamics in the aetiology of the disorder. Psychiatry research. vol 303. 2021-10-27. PMID:34274903. |
lower levels of tubulin alpha 1b in the frontal pole in schizophrenia supports a role for changed cytoskeletal dynamics in the aetiology of the disorder. |
2021-10-27 |
2023-08-13 |
rat |
| Vikas B Raju, Ayushi Shukla, Arpitha Jacob, Rose Dawn Bharath, Vijay Kg Kumar, Shivarama Varambally, Ganesan Venkatasubramanian, Naren P Ra. The frontal pole and cognitive insight in schizophrenia. Psychiatry research. Neuroimaging. vol 308. 2021-05-20. PMID:33340961. |
the frontal pole and cognitive insight in schizophrenia. |
2021-05-20 |
2023-08-13 |
Not clear |
| Hirotaka Sekiguchi, Geoff Pavey, Brian Dea. Altered levels of dopamine transporter in the frontal pole and dorsal striatum in schizophrenia. NPJ schizophrenia. vol 5. issue 1. 2021-01-10. PMID:31792225. |
altered levels of dopamine transporter in the frontal pole and dorsal striatum in schizophrenia. |
2021-01-10 |
2023-08-13 |
human |
| Mu-Hong Chen, Wan-Chen Chang, Ya-Mei Bai, Kai-Lin Huang, Pei-Chi Tu, Tung-Ping Su, Cheng-Ta Li, Wei-Chen Lin, Shih-Jen Tsai, Ju-Wei Hs. Cortico-thalamic dysconnection in early-stage schizophrenia: a functional connectivity magnetic resonance imaging study. European archives of psychiatry and clinical neuroscience. vol 270. issue 3. 2020-11-06. PMID:30953128. |
the patients with early-stage schizophrenia had increased fc of the thalamus with the bilateral postcentral and temporal gyri, inferior occipital cortex, and temporal pole and decreased fc of the thalamus with the vestibulocerebellum and frontal pole compared with the controls. |
2020-11-06 |
2023-08-13 |
Not clear |
| Elizabeth Scarr, Madhara Udawela, Brian Dea. Changed frontal pole gene expression suggest altered interplay between neurotransmitter, developmental, and inflammatory pathways in schizophrenia. NPJ schizophrenia. vol 4. issue 1. 2020-09-30. PMID:29463818. |
changed frontal pole gene expression suggest altered interplay between neurotransmitter, developmental, and inflammatory pathways in schizophrenia. |
2020-09-30 |
2023-08-13 |
human |
| Ícaro A F Oliveira, Tiago M Guimarães, Roberto M Souza, Antônio C Dos Santos, João Paulo Machado-de-Sousa, Jaime E C Hallak, Renata F Leon. Brain functional and perfusional alterations in schizophrenia: an arterial spin labeling study. Psychiatry research. Neuroimaging. vol 272. 2019-05-30. PMID:29229240. |
schizophrenia patients had decreased cbf in the bilateral frontal pole and superior frontal gyrus, right medial frontal gyrus, triangular and opercular parts of the inferior frontal gyrus, posterior division of the left supramarginal gyrus, superior and inferior divisions of the left lateral occipital cortex, and bilateral occipital pole. |
2019-05-30 |
2023-08-13 |
Not clear |
| Toshiyuki Ohtani, Elisabetta Del Re, James J Levitt, Margaret Niznikiewicz, Jun Konishi, Takeshi Asami, Toshiro Kawashima, Tomohide Roppongi, Paul G Nestor, Martha E Shenton, Dean F Salisbury, Robert W McCarle. Progressive symptom-associated prefrontal volume loss occurs in first-episode schizophrenia but not in affective psychosis. Brain structure & function. vol 223. issue 6. 2019-02-28. PMID:29671056. |
the object of this study was to determine whether first-episode schizophrenia (fesz) and first-episode affective psychosis (feaff) patients show initial and progressive pfc gmv reduction in bilateral frontal pole, superior frontal gyrus (sfg), middle frontal gyrus (mfg), and inferior frontal gyrus (ifg) and examine their symptom associations. |
2019-02-28 |
2023-08-13 |
human |